methyldopa has been researched along with Cardiomegaly in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (86.05) | 18.7374 |
| 1990's | 6 (13.95) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FLEMING, PR | 1 |
| CHAMBERLAIN, DA; HOWARD, J | 1 |
| Frohlich, ED; Pegram, BL | 1 |
| Ruskoaho, H | 1 |
| Chandler, T; Franklin, BB; Muhammad, A; Plappert, T; Reichek, N; St John Sutton, M | 1 |
| Drayer, JI; Gardin, JM; Lipson, JL; Weber, MA | 1 |
| Blumenstein, BA; Cotsonis, GA; Douglas, MB; Felner, JM; Hall, WD; Knudtson, ML; Porter, VD; Schlant, RC; Unger, DJ; Wollam, GL | 1 |
| Fernandez, PG; Furlong, L; Gill, V; Kim, BK; Ko, P; Lewis, H; McDonald, J; McManamon, P; Nolan, R; Reichek, N | 1 |
| Hilewitz, H; Rogel, S; Weinstein, M | 1 |
| Condorelli, M; Cuocolo, A; De Luca, N; De Simone, A; Ricciardelli, B; Rosiello, G; Trimarco, B; Veniero, AM; Volpe, M | 1 |
| Bentivoglio, M; Corea, L; Motolese, M; Verdecchia, P | 1 |
| Hallbäck-Nordlander, MI; Lundin, SA | 1 |
| Frohlich, ED | 2 |
| Frohlich, ED; Ishise, S; Pegram, BL | 2 |
| Limas, CJ; Spier, SS | 1 |
| Fouad, FM; Nakashima, Y; Salcedo, EE; Tarazi, RC | 1 |
| Abassi, ZA; Cuda, G; Golomb, E; Keiser, HR; Panchal, VR; Stylianou, M; Trachewsky, D | 1 |
| Bumpus, FM; Sen, S; Tarazi, RC | 2 |
| Herget, J; Suggett, A | 1 |
| Falase, AO | 1 |
| Herget, J; Suggett, AJ | 1 |
| Dolce, E; Pieri, R; Pirrelli, R | 1 |
| Manegold, C; Patzschke, U | 1 |
| Anderson, SC; Davis, JW; Tomanek, RJ | 1 |
| Markenson, JA; Sherman, RL | 1 |
| Endo, T; Izumiyama, T; Komatus, H; Kubota, T; Nagata, H; Oba, M; Yamada, T | 1 |
| Frohlich, ED; Tarazi, RC | 1 |
| Van Hoof, R | 1 |
| Cífková, R; Frídl, P; Niederle, P; Skibová, J; Widimský, J | 1 |
| Horio, T; Kohno, M; Kurihara, N; Murakawa, K; Takeda, T; Yasunari, K; Yokokawa, K | 1 |
| Fontan, M; Gallo, A; Gómez Llambi, H; Kuraja, I; Massadi, A; Taquini, CM | 1 |
| Motz, W; Strauer, BE | 1 |
| Zähringer, J | 1 |
| Agati, L; Dagianti, A; Fedele, F; Penco, M; Sciomer, S | 1 |
| Leppäluoto, J; Ruskoaho, H | 1 |
| Henderson, S; Massie, BM; Parmley, WW; Sievers, R; Szlachcic, J; Tubau, JF; Wikman-Coffelt, J | 1 |
| Feldstein, CA; Olivieri, AO; Sabarís, RP | 1 |
| Fernandez, PG; Kim, BK; Lee, CC; Snedden, W | 1 |
| Bumpus, FM; Khairallah, PA; Sen, S; Tarazi, RC | 1 |
| Branche, G; Chiles, B; Garnier, C; Kilcoyne, MM; Soland, T; Thomson, GE; Williams, M | 1 |
5 review(s) available for methyldopa and Cardiomegaly
| Article | Year |
|---|---|
Cardiovascular adjustment to antiadrenergic agents.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cardiovascular System; Hemodynamics; Hypertension; Male; Methyldopa; Rats; Rats, Inbred Strains; Vasodilator Agents | 1983 |
Regression of cardiac hypertrophy with drug treatment in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Collagen; Diuretics; Heart; Hemodynamics; Humans; Hypertension; Methyldopa; Myocardium; Myosins; Ornithine Decarboxylase; Polyamines; Rats; Rats, Inbred SHR; Vascular Resistance; Vasodilator Agents | 1984 |
Methyldopa. Mechanisms and treatment 25 years later.
Topics: Carboxy-Lyases; Cardiomegaly; Cardiovascular System; Hemodynamics; Humans; Methyldopa; Physical Exertion; Posture; Receptors, Adrenergic, alpha; Renin; Synaptic Transmission | 1980 |
Is arterial pressure the sole factor responsible for hypertensive cardiac hypertrophy?
Topics: Angiotensins; Animals; Blood Pressure; Cardiomegaly; Humans; Hypertension; Methyldopa; Rats; Renin; Sympatholytics | 1979 |
Left ventricular hypertrophy: dissociation of structural and functional effects by therapy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Cardiomegaly; Humans; Hypertension; Methyldopa; Rats; Rats, Inbred SHR | 1991 |
5 trial(s) available for methyldopa and Cardiomegaly
| Article | Year |
|---|---|
Time course of regression of left ventricular hypertrophy in treated hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Clinical Trials as Topic; Drug Therapy, Combination; Echocardiography; Electrocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Organ Size; Prospective Studies; Random Allocation; Time Factors | 1983 |
The correlation of changes in systolic blood pressure with regional anatomical regression of hypertensive left ventricular hypertrophy in patients on chronic antihypertensive therapy (greater than 1 year): alpha-methyldopa compared to propranolol.
Topics: Adult; Blood Pressure; Cardiomegaly; Echocardiography; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Middle Aged; Myocardium; Propranolol | 1984 |
Left ventricular hypertrophy in elderly hypertensive patients: a report from the European Working Party on High Blood Pressure in the Elderly trial.
Topics: Aged; Cardiomegaly; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Survival Rate; Triamterene | 1991 |
Comparison between the effects of urapidil and methyldopa on left ventricular hypertrophy and haemodynamics in humans.
Topics: Adult; Aged; Antihypertensive Agents; Cardiomegaly; Clinical Trials as Topic; Double-Blind Method; Echocardiography; Female; Hemodynamics; Humans; Male; Methyldopa; Middle Aged; Piperazines; Random Allocation | 1988 |
A novel therapeutic approach for reversal of left ventricular hypertrophy and blood pressure control in hypertensive patients treated with alpha-methyldopa or propranolol.
Topics: Adult; Blood Pressure; Cardiomegaly; Clinical Trials as Topic; Echocardiography; Female; Heart Rate; Heart Ventricles; Humans; Hypertension; Male; Methyldopa; Middle Aged; Posture; Propranolol | 1985 |
33 other study(ies) available for methyldopa and Cardiomegaly
| Article | Year |
|---|---|
HYPERTENSIVE HEART DISEASE.
Topics: Angina Pectoris; Cardiomegaly; Coronary Disease; Drug Therapy; Dyspnea; Dyspnea, Paroxysmal; Electrocardiography; Fundus Oculi; Guanethidine; Heart Auscultation; Humans; Hypertension; Methyldopa; Ophthalmoscopy; Radiography, Thoracic | 1964 |
GUANETHIDINE AND METHYLDOPA: A HAEMODYNAMIC STUDY.
Topics: Blood Circulation; Blood Pressure Determination; Cardiomegaly; Drug Therapy; Dye Dilution Technique; Electrocardiography; Exercise Test; Guanethidine; Hemodynamics; Humans; Hypertension; Methyldopa; Pharmacology; Posture; Statistics as Topic | 1964 |
Reversal of left ventricular hypertrophy by antihypertensive therapy.
Topics: Antihypertensive Agents; Cardiomegaly; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Time Factors | 1982 |
Effect of long-term antihypertensive therapy on cardiac anatomy in patients with essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Heart Rate; Heart Septum; Humans; Hydrochlorothiazide; Hypertension; Long-Term Care; Male; Methyldopa; Middle Aged; Myocardium | 1983 |
The effect of single-dose methyldopa and diuretic on BP and left ventricular mass.
Topics: Adult; Aged; Amiloride; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines; Stroke Volume; Time Factors | 1984 |
[Effects of long-term treatment with various antihypertensive drugs on the cardiac mass and on the hemodynamics of patients with essential arterial hypertension].
Topics: Adult; Cardiac Output; Cardiomegaly; Clonidine; Echocardiography; Heart; Humans; Hypertension; Methyldopa; Metoprolol; Middle Aged | 1983 |
Echocardiography in clinical pharmacology: developing new concepts on the pathophysiology of left ventricular hypertrophy in arterial hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Echocardiography; Humans; Hypertension; Methyldopa | 1983 |
Regression of structural cardiovascular changes by antihypertensive therapy in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cardiovascular System; Circadian Rhythm; Felodipine; Heart Rate; Hypertension; Methyldopa; Metoprolol; Nifedipine; Rats; Rats, Inbred SHR; Time Factors | 1984 |
Disparate effects of methyldopa and clonidine on cardiac mass and haemodynamics in rats.
Topics: Animals; Body Weight; Cardiomegaly; Clonidine; Hemodynamics; Hypertension; Methyldopa; Myocardium; Organ Size; Rats; Regional Blood Flow | 1980 |
Effect of antihypertensive therapy on calcium transport by cardiac sarcoplasmic reticulum of SHRs.
Topics: Adenosine Triphosphatases; Animals; Biological Transport; Calcium; Cardiomegaly; Hydralazine; Hypertension; Male; Methyldopa; Myocardium; Rats; Sarcoplasmic Reticulum | 1980 |
Effect of methyldopa, clonidine, and hydralazine on cardiac mass and haemodynamics in Wistar Kyoto and spontaneously hypertensive rats.
Topics: Animals; Cardiomegaly; Clonidine; Heart; Hemodynamics; Hydralazine; Hypertension; Methyldopa; Organ Size; Rats; Rats, Inbred Strains | 1982 |
Reversal of left ventricular hypertrophy in hypertensive patients treated with methyldopa. Lack of association with blood pressure control.
Topics: Adult; Blood Pressure; Cardiac Volume; Cardiomegaly; Echocardiography; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Myocardial Contraction | 1982 |
Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats.
Topics: Actins; Angiotensin II; Animals; Base Sequence; Biphenyl Compounds; Blood Pressure; Captopril; Cardiomegaly; DNA; DNA Primers; Dose-Response Relationship, Drug; Gene Expression; Genes, fos; Heart; Hydralazine; Hydroxyproline; Imidazoles; Isoproterenol; Labetalol; Losartan; Male; Methyldopa; Molecular Sequence Data; Myocardium; Myosins; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrazoles; Transcription, Genetic | 1994 |
Biochemical changes associated with development and reversal of cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Animals; Cardiomegaly; DNA; Hydroxyproline; Hypertension; Methyldopa; Myocardium; Myosins; Organ Size; Rats; RNA | 1976 |
Proceedings: Effect of alpha-methyldopa on pulmonary hypertension induced by chronic hypoxia in rats.
Topics: Animals; Cardiomegaly; Hypertension, Pulmonary; Hypoxia; Methyldopa; Rats | 1976 |
Cardiomegaly of unknown origin among Nigerian adults: role of hypertension in its aetiology.
Topics: Adolescent; Adult; Aged; Alcoholic Beverages; Benzothiadiazines; Blood Pressure; Cardiomegaly; Cardiomyopathies; Child; Diet; Digoxin; Diuretics; Female; Furosemide; Heart Failure; Humans; Hypertension; Male; Methyldopa; Middle Aged; Nigeria; Sodium Chloride Symporter Inhibitors | 1977 |
Effect of alpha-methyldopa on the pulmonary vascular changes induced by chronic hypoxia in rats.
Topics: Animals; Blood Pressure; Cardiomegaly; Hypertension, Pulmonary; Hypoxia; Male; Methyldopa; Pulmonary Artery; Rats | 1977 |
Cardiac hypertrophy and antihypertensive therapy.
Topics: Animals; Cardiomegaly; DNA; Hydroxyproline; Hypertension; Male; Methyldopa; Minoxidil; Myocardium; Propranolol; Pyrimidines; Rats; Renin; RNA | 1977 |
[Alphamethyldopa and the catecholamine content of the hypertrophic myocardium].
Topics: Animals; Blood Pressure; Cardiomegaly; Catecholamines; Desoxycorticosterone; Heart; Methyldopa; Myocardium; Organ Size; Rats; Vanilmandelic Acid | 1978 |
[Regression of left ventricular hypertophy in the ECG during antihypertensive treatment: preliminary observations (author's transl)].
Topics: Adult; Aged; Cardiomegaly; Chlorthalidone; Electrocardiography; Female; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; Reserpine | 1979 |
The effects of alpha-methyldopa on cardiac hypertrophy in spontaneously hypertensive rats: ultrastructural, stereological, and morphometric analysis.
Topics: Animals; Cardiomegaly; Endocardium; Hypertension; Male; Methyldopa; Microscopy, Electron; Myocardium; Pericardium; Rats | 1979 |
Renal involvement in progressive systemic sclerosis: prolonged survival with aggressive antihypertensive management.
Topics: Adult; Antihypertensive Agents; Cardiomegaly; Digoxin; Drug Therapy, Combination; Female; Furosemide; Humans; Hydralazine; Hypertension, Malignant; Hypertension, Renal; Kidney Diseases; Methyldopa; Minoxidil; Propranolol; Scleroderma, Systemic; Time Factors | 1979 |
Effects of antihypertensive treatment on left ventricular hypertrophy in patients with essential hypertension.
Topics: Adult; Aged; Animals; Antihypertensive Agents; Cardiomegaly; Electrocardiography; Female; Heart Ventricles; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; Propranolol; Rats; Trichlormethiazide | 1979 |
Cardiac hypertrophy in hypertension.
Topics: Blood Pressure; Cardiac Output; Cardiac Volume; Cardiomegaly; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echocardiography; Follow-Up Studies; Humans; Hypertension; Male; Methyldopa; Metipranolol; Middle Aged; Pindolol; Propanolamines | 1990 |
Effect on atrial natriuretic peptides of chronic treatment with alpha-methyldopa and hydralazine in spontaneously hypertensive rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Heart Atria; Heart Ventricles; Hydralazine; Hypertension; Male; Methyldopa; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors | 1990 |
[Effect of alpha methyldopa on heart in renovascular hypertension].
Topics: Animals; Blood Pressure; Cardiomegaly; Heart Rate; Hypertension, Renovascular; Isoproterenol; Male; Methyldopa; Myocardial Contraction; Organ Size; Rats; Rats, Inbred Strains | 1990 |
[What is safe in the therapy of hypertensive heart disease?].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clonidine; Coronary Disease; Digitalis Glycosides; Diuretics; Female; Heart Failure; Hemodynamics; Humans; Hypertension; Methyldopa; Pregnancy; Rats; Vasodilator Agents | 1985 |
[Regression of biochemical changes in heart muscle hypertrophy].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Collagen; Humans; Hypertension; Isoenzymes; Methyldopa; Muscle Proteins; Myosins | 1985 |
Left ventricular filling pattern in hypertensive patients after reversal of myocardial hypertrophy.
Topics: Blood Pressure; Cardiac Volume; Cardiomegaly; Echocardiography; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Myocardial Contraction | 1987 |
Immunoreactive atrial natriuretic peptide in ventricles, atria, hypothalamus, and plasma of genetically hypertensive rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cardiomegaly; Heart Rate; Hypertension; Hypothalamus; Kidney; Male; Methyldopa; Minoxidil; Myocardium; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1988 |
Diltiazem prevents hypertrophy progression, preserves systolic function, and normalises myocardial oxygen utilisation in the spontaneously hypertensive rat.
Topics: Animals; Cardiomegaly; Coronary Circulation; Diltiazem; Heart; Hypertension; In Vitro Techniques; Methyldopa; Myocardium; Myosins; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole | 1987 |
Cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Age Factors; Angiotensin II; Animals; Cardiomegaly; DNA; Heart Ventricles; Hydralazine; Hypertension; Methyldopa; Organ Size; Rats; Rats, Inbred Strains; Renin | 1974 |
Characteristics of hypertension in the black population.
Topics: Adult; Angiotensin II; Animals; Black or African American; Cardiomegaly; Cerebrovascular Disorders; Chlorthalidone; Coronary Disease; Drug Therapy, Combination; Female; Guanethidine; Heart Ventricles; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; New York City; Rabbits; Radioimmunoassay; Renin; Sodium; Spironolactone | 1974 |