Page last updated: 2024-08-23

methyldopa and Cardiomegaly

methyldopa has been researched along with Cardiomegaly in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199037 (86.05)18.7374
1990's6 (13.95)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
FLEMING, PR1
CHAMBERLAIN, DA; HOWARD, J1
Frohlich, ED; Pegram, BL1
Ruskoaho, H1
Chandler, T; Franklin, BB; Muhammad, A; Plappert, T; Reichek, N; St John Sutton, M1
Drayer, JI; Gardin, JM; Lipson, JL; Weber, MA1
Blumenstein, BA; Cotsonis, GA; Douglas, MB; Felner, JM; Hall, WD; Knudtson, ML; Porter, VD; Schlant, RC; Unger, DJ; Wollam, GL1
Fernandez, PG; Furlong, L; Gill, V; Kim, BK; Ko, P; Lewis, H; McDonald, J; McManamon, P; Nolan, R; Reichek, N1
Hilewitz, H; Rogel, S; Weinstein, M1
Condorelli, M; Cuocolo, A; De Luca, N; De Simone, A; Ricciardelli, B; Rosiello, G; Trimarco, B; Veniero, AM; Volpe, M1
Bentivoglio, M; Corea, L; Motolese, M; Verdecchia, P1
Hallbäck-Nordlander, MI; Lundin, SA1
Frohlich, ED2
Frohlich, ED; Ishise, S; Pegram, BL2
Limas, CJ; Spier, SS1
Fouad, FM; Nakashima, Y; Salcedo, EE; Tarazi, RC1
Abassi, ZA; Cuda, G; Golomb, E; Keiser, HR; Panchal, VR; Stylianou, M; Trachewsky, D1
Bumpus, FM; Sen, S; Tarazi, RC2
Herget, J; Suggett, A1
Falase, AO1
Herget, J; Suggett, AJ1
Dolce, E; Pieri, R; Pirrelli, R1
Manegold, C; Patzschke, U1
Anderson, SC; Davis, JW; Tomanek, RJ1
Markenson, JA; Sherman, RL1
Endo, T; Izumiyama, T; Komatus, H; Kubota, T; Nagata, H; Oba, M; Yamada, T1
Frohlich, ED; Tarazi, RC1
Van Hoof, R1
Cífková, R; Frídl, P; Niederle, P; Skibová, J; Widimský, J1
Horio, T; Kohno, M; Kurihara, N; Murakawa, K; Takeda, T; Yasunari, K; Yokokawa, K1
Fontan, M; Gallo, A; Gómez Llambi, H; Kuraja, I; Massadi, A; Taquini, CM1
Motz, W; Strauer, BE1
Zähringer, J1
Agati, L; Dagianti, A; Fedele, F; Penco, M; Sciomer, S1
Leppäluoto, J; Ruskoaho, H1
Henderson, S; Massie, BM; Parmley, WW; Sievers, R; Szlachcic, J; Tubau, JF; Wikman-Coffelt, J1
Feldstein, CA; Olivieri, AO; Sabarís, RP1
Fernandez, PG; Kim, BK; Lee, CC; Snedden, W1
Bumpus, FM; Khairallah, PA; Sen, S; Tarazi, RC1
Branche, G; Chiles, B; Garnier, C; Kilcoyne, MM; Soland, T; Thomson, GE; Williams, M1

Reviews

5 review(s) available for methyldopa and Cardiomegaly

ArticleYear
Cardiovascular adjustment to antiadrenergic agents.
    The American journal of medicine, 1983, Sep-26, Volume: 75, Issue:3A

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cardiovascular System; Hemodynamics; Hypertension; Male; Methyldopa; Rats; Rats, Inbred Strains; Vasodilator Agents

1983
Regression of cardiac hypertrophy with drug treatment in spontaneously hypertensive rats.
    Medical biology, 1984, Volume: 62, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Collagen; Diuretics; Heart; Hemodynamics; Humans; Hypertension; Methyldopa; Myocardium; Myosins; Ornithine Decarboxylase; Polyamines; Rats; Rats, Inbred SHR; Vascular Resistance; Vasodilator Agents

1984
Methyldopa. Mechanisms and treatment 25 years later.
    Archives of internal medicine, 1980, Volume: 140, Issue:7

    Topics: Carboxy-Lyases; Cardiomegaly; Cardiovascular System; Hemodynamics; Humans; Methyldopa; Physical Exertion; Posture; Receptors, Adrenergic, alpha; Renin; Synaptic Transmission

1980
Is arterial pressure the sole factor responsible for hypertensive cardiac hypertrophy?
    The American journal of cardiology, 1979, Oct-22, Volume: 44, Issue:5

    Topics: Angiotensins; Animals; Blood Pressure; Cardiomegaly; Humans; Hypertension; Methyldopa; Rats; Renin; Sympatholytics

1979
Left ventricular hypertrophy: dissociation of structural and functional effects by therapy.
    Advances in experimental medicine and biology, 1991, Volume: 308

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Cardiomegaly; Humans; Hypertension; Methyldopa; Rats; Rats, Inbred SHR

1991

Trials

5 trial(s) available for methyldopa and Cardiomegaly

ArticleYear
Time course of regression of left ventricular hypertrophy in treated hypertensive patients.
    The American journal of medicine, 1983, Sep-26, Volume: 75, Issue:3A

    Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Clinical Trials as Topic; Drug Therapy, Combination; Echocardiography; Electrocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Organ Size; Prospective Studies; Random Allocation; Time Factors

1983
The correlation of changes in systolic blood pressure with regional anatomical regression of hypertensive left ventricular hypertrophy in patients on chronic antihypertensive therapy (greater than 1 year): alpha-methyldopa compared to propranolol.
    Current medical research and opinion, 1984, Volume: 8, Issue:10

    Topics: Adult; Blood Pressure; Cardiomegaly; Echocardiography; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Middle Aged; Myocardium; Propranolol

1984
Left ventricular hypertrophy in elderly hypertensive patients: a report from the European Working Party on High Blood Pressure in the Elderly trial.
    The American journal of medicine, 1991, Volume: 90, Issue:3A

    Topics: Aged; Cardiomegaly; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Survival Rate; Triamterene

1991
Comparison between the effects of urapidil and methyldopa on left ventricular hypertrophy and haemodynamics in humans.
    Drugs, 1988, Volume: 35 Suppl 6

    Topics: Adult; Aged; Antihypertensive Agents; Cardiomegaly; Clinical Trials as Topic; Double-Blind Method; Echocardiography; Female; Hemodynamics; Humans; Male; Methyldopa; Middle Aged; Piperazines; Random Allocation

1988
A novel therapeutic approach for reversal of left ventricular hypertrophy and blood pressure control in hypertensive patients treated with alpha-methyldopa or propranolol.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:4

    Topics: Adult; Blood Pressure; Cardiomegaly; Clinical Trials as Topic; Echocardiography; Female; Heart Rate; Heart Ventricles; Humans; Hypertension; Male; Methyldopa; Middle Aged; Posture; Propranolol

1985

Other Studies

33 other study(ies) available for methyldopa and Cardiomegaly

ArticleYear
HYPERTENSIVE HEART DISEASE.
    The Practitioner, 1964, Volume: 193

    Topics: Angina Pectoris; Cardiomegaly; Coronary Disease; Drug Therapy; Dyspnea; Dyspnea, Paroxysmal; Electrocardiography; Fundus Oculi; Guanethidine; Heart Auscultation; Humans; Hypertension; Methyldopa; Ophthalmoscopy; Radiography, Thoracic

1964
GUANETHIDINE AND METHYLDOPA: A HAEMODYNAMIC STUDY.
    British heart journal, 1964, Volume: 26

    Topics: Blood Circulation; Blood Pressure Determination; Cardiomegaly; Drug Therapy; Dye Dilution Technique; Electrocardiography; Exercise Test; Guanethidine; Hemodynamics; Humans; Hypertension; Methyldopa; Pharmacology; Posture; Statistics as Topic

1964
Reversal of left ventricular hypertrophy by antihypertensive therapy.
    European heart journal, 1982, Volume: 3 Suppl A

    Topics: Antihypertensive Agents; Cardiomegaly; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Time Factors

1982
Effect of long-term antihypertensive therapy on cardiac anatomy in patients with essential hypertension.
    The American journal of medicine, 1983, Sep-26, Volume: 75, Issue:3A

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Heart Rate; Heart Septum; Humans; Hydrochlorothiazide; Hypertension; Long-Term Care; Male; Methyldopa; Middle Aged; Myocardium

1983
The effect of single-dose methyldopa and diuretic on BP and left ventricular mass.
    Archives of internal medicine, 1984, Volume: 144, Issue:8

    Topics: Adult; Aged; Amiloride; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines; Stroke Volume; Time Factors

1984
[Effects of long-term treatment with various antihypertensive drugs on the cardiac mass and on the hemodynamics of patients with essential arterial hypertension].
    Cardiologia (Rome, Italy), 1983, Volume: 28, Issue:8

    Topics: Adult; Cardiac Output; Cardiomegaly; Clonidine; Echocardiography; Heart; Humans; Hypertension; Methyldopa; Metoprolol; Middle Aged

1983
Echocardiography in clinical pharmacology: developing new concepts on the pathophysiology of left ventricular hypertrophy in arterial hypertension.
    International journal of clinical pharmacology research, 1983, Volume: 3, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Echocardiography; Humans; Hypertension; Methyldopa

1983
Regression of structural cardiovascular changes by antihypertensive therapy in spontaneously hypertensive rats.
    Journal of hypertension, 1984, Volume: 2, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cardiovascular System; Circadian Rhythm; Felodipine; Heart Rate; Hypertension; Methyldopa; Metoprolol; Nifedipine; Rats; Rats, Inbred SHR; Time Factors

1984
Disparate effects of methyldopa and clonidine on cardiac mass and haemodynamics in rats.
    Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6

    Topics: Animals; Body Weight; Cardiomegaly; Clonidine; Hemodynamics; Hypertension; Methyldopa; Myocardium; Organ Size; Rats; Regional Blood Flow

1980
Effect of antihypertensive therapy on calcium transport by cardiac sarcoplasmic reticulum of SHRs.
    Cardiovascular research, 1980, Volume: 14, Issue:12

    Topics: Adenosine Triphosphatases; Animals; Biological Transport; Calcium; Cardiomegaly; Hydralazine; Hypertension; Male; Methyldopa; Myocardium; Rats; Sarcoplasmic Reticulum

1980
Effect of methyldopa, clonidine, and hydralazine on cardiac mass and haemodynamics in Wistar Kyoto and spontaneously hypertensive rats.
    Cardiovascular research, 1982, Volume: 16, Issue:1

    Topics: Animals; Cardiomegaly; Clonidine; Heart; Hemodynamics; Hydralazine; Hypertension; Methyldopa; Organ Size; Rats; Rats, Inbred Strains

1982
Reversal of left ventricular hypertrophy in hypertensive patients treated with methyldopa. Lack of association with blood pressure control.
    The American journal of cardiology, 1982, Volume: 49, Issue:4

    Topics: Adult; Blood Pressure; Cardiac Volume; Cardiomegaly; Echocardiography; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Myocardial Contraction

1982
Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats.
    The American journal of physiology, 1994, Volume: 267, Issue:4 Pt 2

    Topics: Actins; Angiotensin II; Animals; Base Sequence; Biphenyl Compounds; Blood Pressure; Captopril; Cardiomegaly; DNA; DNA Primers; Dose-Response Relationship, Drug; Gene Expression; Genes, fos; Heart; Hydralazine; Hydroxyproline; Imidazoles; Isoproterenol; Labetalol; Losartan; Male; Methyldopa; Molecular Sequence Data; Myocardium; Myosins; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrazoles; Transcription, Genetic

1994
Biochemical changes associated with development and reversal of cardiac hypertrophy in spontaneously hypertensive rats.
    Cardiovascular research, 1976, Volume: 10, Issue:2

    Topics: Animals; Cardiomegaly; DNA; Hydroxyproline; Hypertension; Methyldopa; Myocardium; Myosins; Organ Size; Rats; RNA

1976
Proceedings: Effect of alpha-methyldopa on pulmonary hypertension induced by chronic hypoxia in rats.
    The Journal of physiology, 1976, Volume: 258, Issue:1

    Topics: Animals; Cardiomegaly; Hypertension, Pulmonary; Hypoxia; Methyldopa; Rats

1976
Cardiomegaly of unknown origin among Nigerian adults: role of hypertension in its aetiology.
    British heart journal, 1977, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Aged; Alcoholic Beverages; Benzothiadiazines; Blood Pressure; Cardiomegaly; Cardiomyopathies; Child; Diet; Digoxin; Diuretics; Female; Furosemide; Heart Failure; Humans; Hypertension; Male; Methyldopa; Middle Aged; Nigeria; Sodium Chloride Symporter Inhibitors

1977
Effect of alpha-methyldopa on the pulmonary vascular changes induced by chronic hypoxia in rats.
    Clinical science and molecular medicine, 1977, Volume: 53, Issue:4

    Topics: Animals; Blood Pressure; Cardiomegaly; Hypertension, Pulmonary; Hypoxia; Male; Methyldopa; Pulmonary Artery; Rats

1977
Cardiac hypertrophy and antihypertensive therapy.
    Cardiovascular research, 1977, Volume: 11, Issue:5

    Topics: Animals; Cardiomegaly; DNA; Hydroxyproline; Hypertension; Male; Methyldopa; Minoxidil; Myocardium; Propranolol; Pyrimidines; Rats; Renin; RNA

1977
[Alphamethyldopa and the catecholamine content of the hypertrophic myocardium].
    Bollettino della Societa italiana di biologia sperimentale, 1978, Feb-24, Volume: 53, Issue:24

    Topics: Animals; Blood Pressure; Cardiomegaly; Catecholamines; Desoxycorticosterone; Heart; Methyldopa; Myocardium; Organ Size; Rats; Vanilmandelic Acid

1978
[Regression of left ventricular hypertophy in the ECG during antihypertensive treatment: preliminary observations (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1979, Jun-08, Volume: 104, Issue:23

    Topics: Adult; Aged; Cardiomegaly; Chlorthalidone; Electrocardiography; Female; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; Reserpine

1979
The effects of alpha-methyldopa on cardiac hypertrophy in spontaneously hypertensive rats: ultrastructural, stereological, and morphometric analysis.
    Cardiovascular research, 1979, Volume: 13, Issue:3

    Topics: Animals; Cardiomegaly; Endocardium; Hypertension; Male; Methyldopa; Microscopy, Electron; Myocardium; Pericardium; Rats

1979
Renal involvement in progressive systemic sclerosis: prolonged survival with aggressive antihypertensive management.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:10

    Topics: Adult; Antihypertensive Agents; Cardiomegaly; Digoxin; Drug Therapy, Combination; Female; Furosemide; Humans; Hydralazine; Hypertension, Malignant; Hypertension, Renal; Kidney Diseases; Methyldopa; Minoxidil; Propranolol; Scleroderma, Systemic; Time Factors

1979
Effects of antihypertensive treatment on left ventricular hypertrophy in patients with essential hypertension.
    Journal of the American Geriatrics Society, 1979, Volume: 27, Issue:11

    Topics: Adult; Aged; Animals; Antihypertensive Agents; Cardiomegaly; Electrocardiography; Female; Heart Ventricles; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; Propranolol; Rats; Trichlormethiazide

1979
Cardiac hypertrophy in hypertension.
    Cor et vasa, 1990, Volume: 32, Issue:1

    Topics: Blood Pressure; Cardiac Output; Cardiac Volume; Cardiomegaly; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echocardiography; Follow-Up Studies; Humans; Hypertension; Male; Methyldopa; Metipranolol; Middle Aged; Pindolol; Propanolamines

1990
Effect on atrial natriuretic peptides of chronic treatment with alpha-methyldopa and hydralazine in spontaneously hypertensive rats.
    American journal of hypertension, 1990, Volume: 3, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Heart Atria; Heart Ventricles; Hydralazine; Hypertension; Male; Methyldopa; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors

1990
[Effect of alpha methyldopa on heart in renovascular hypertension].
    Medicina, 1990, Volume: 50, Issue:2

    Topics: Animals; Blood Pressure; Cardiomegaly; Heart Rate; Hypertension, Renovascular; Isoproterenol; Male; Methyldopa; Myocardial Contraction; Organ Size; Rats; Rats, Inbred Strains

1990
[What is safe in the therapy of hypertensive heart disease?].
    Der Internist, 1985, Volume: 26, Issue:12

    Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clonidine; Coronary Disease; Digitalis Glycosides; Diuretics; Female; Heart Failure; Hemodynamics; Humans; Hypertension; Methyldopa; Pregnancy; Rats; Vasodilator Agents

1985
[Regression of biochemical changes in heart muscle hypertrophy].
    Zeitschrift fur Kardiologie, 1985, Volume: 74 Suppl 7

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Collagen; Humans; Hypertension; Isoenzymes; Methyldopa; Muscle Proteins; Myosins

1985
Left ventricular filling pattern in hypertensive patients after reversal of myocardial hypertrophy.
    International journal of cardiology, 1987, Volume: 17, Issue:2

    Topics: Blood Pressure; Cardiac Volume; Cardiomegaly; Echocardiography; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Myocardial Contraction

1987
Immunoreactive atrial natriuretic peptide in ventricles, atria, hypothalamus, and plasma of genetically hypertensive rats.
    Circulation research, 1988, Volume: 62, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cardiomegaly; Heart Rate; Hypertension; Hypothalamus; Kidney; Male; Methyldopa; Minoxidil; Myocardium; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1988
Diltiazem prevents hypertrophy progression, preserves systolic function, and normalises myocardial oxygen utilisation in the spontaneously hypertensive rat.
    Cardiovascular research, 1987, Volume: 21, Issue:8

    Topics: Animals; Cardiomegaly; Coronary Circulation; Diltiazem; Heart; Hypertension; In Vitro Techniques; Methyldopa; Myocardium; Myosins; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole

1987
Cardiac hypertrophy in spontaneously hypertensive rats.
    Circulation research, 1974, Volume: 35, Issue:5

    Topics: Age Factors; Angiotensin II; Animals; Cardiomegaly; DNA; Heart Ventricles; Hydralazine; Hypertension; Methyldopa; Organ Size; Rats; Rats, Inbred Strains; Renin

1974
Characteristics of hypertension in the black population.
    Circulation, 1974, Volume: 50, Issue:5

    Topics: Adult; Angiotensin II; Animals; Black or African American; Cardiomegaly; Cerebrovascular Disorders; Chlorthalidone; Coronary Disease; Drug Therapy, Combination; Female; Guanethidine; Heart Ventricles; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; New York City; Rabbits; Radioimmunoassay; Renin; Sodium; Spironolactone

1974