methyldimethylaminoazobenzene has been researched along with Experimental Neoplasms in 50 studies
Methyldimethylaminoazobenzene: A very potent liver carcinogen.
3-methyl-4'-dimethylaminoazobenzene : A member of the class of azobenzenes that is azobenzene in which one of the phenyl groups is substituted at position 3 by a methyl group, while the other is substituted at position 4 by a dimethylamino group. It is a potent liver carcinogen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The chronobiology of ornithine decarboxylase (ODC) activity in livers was investigated in noninbred Sprague-Dawley rats fed for 5 months with a basal diet or diets with 3-methyl-4'-(dimethylamino)azobenzene (3-Me-DAB) that were oncogenic or caused bile duct hyperplasia (1-naphthylisothiocyanate) (NIT)." | 3.66 | Changes in th circadian rhythm of ornithine decarboxylase in rat liver during chemical hepatocarcinogenesis. ( Ferioli, ME; Fraschini, F; Majorino, G; Modena, D; Puerari, M; Scalabrino, G, 1981) |
| "However, mutations and chromosomal aberrations were significantly induced by N-acetoxy-4-methylaminoazobenzene, an active metabolite of 4-dimethylaminoazobenzene or 3'-Me-DAB in the presence of liver microsomes." | 1.26 | Effect of 3'-methyl-4-dimethylaminoazobenzene in the induction of malignant transformation and of 8-azaguanine-resistant mutations and chromosomal aberrations in a diploid clone derived from normal rat liver cells in culture. ( Sato, J; Tokiwa, T, 1982) |
| "The fractions separated from the hepatoma were stimulated more than those of kidney by gamma-glutamyl group acceptor." | 1.26 | Higher transpeptidation activity and broad acceptor specificity of gamma-glutamyltransferases of tumors. ( Higashi, T; Nakashima, K; Naruse, A; Nomura, T; Tateishi, N, 1976) |
| "The urine of 90% of hepatoma-bearing rats contained AFP at the time of killing." | 1.26 | Excretion of alpha-foetoprotein in the urine of rats during exposure to 3'-methyl-4-dimethylaminoazobenzene. ( Boss, JH; Okon, E; Rosenmann, E; Zajicek, G, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MEECHAN, RJ | 1 |
| McCAFFERTY, DE | 1 |
| JONES, RS | 1 |
| HADJIOLOV, D | 1 |
| OLSON, KB | 1 |
| EDWARDS, CF | 1 |
| HEGGEN, GE | 1 |
| STEIN, AA | 1 |
| RICHARDSON, HL | 1 |
| STIER, AR | 1 |
| BORSOS-NACHTNEBEL, E | 1 |
| Kojima, J | 2 |
| Kanatani, M | 2 |
| Nakamura, N | 2 |
| Kashiwagi, T | 1 |
| Tohjoh, F | 1 |
| Akiyama, M | 2 |
| Kojima, S | 2 |
| Hama, Y | 1 |
| Kubodera, A | 2 |
| Blackburn, GR | 1 |
| Andrews, JP | 1 |
| Custer, RP | 1 |
| Sorof, S | 1 |
| Fujii, K | 1 |
| Weber, A | 2 |
| Le Provost, E | 1 |
| Boisnard-Rissel, M | 1 |
| Berges, J | 1 |
| Schapira, F | 1 |
| Guillouzo, A | 1 |
| Daoud, AH | 1 |
| Griffin, AC | 1 |
| Pitot, HC | 1 |
| Goldsworthy, T | 1 |
| Moran, S | 1 |
| Sirica, AE | 1 |
| Weeks, J | 1 |
| Sasaki, T | 1 |
| Flaks, B | 1 |
| Flaks, A | 1 |
| Milsom, A | 1 |
| Tokiwa, T | 1 |
| Sato, J | 1 |
| Cottreau, D | 1 |
| Henry, J | 1 |
| Phan Dinh Tuy, F | 1 |
| Skala, H | 1 |
| Kahn, A | 1 |
| Scalabrino, G | 1 |
| Ferioli, ME | 1 |
| Puerari, M | 1 |
| Modena, D | 1 |
| Fraschini, F | 1 |
| Majorino, G | 1 |
| Hino, O | 1 |
| Kitagawa, T | 1 |
| Kitagawa, Y | 1 |
| Kuroiwa, Y | 1 |
| Tateishi, N | 1 |
| Higashi, T | 1 |
| Nomura, T | 1 |
| Naruse, A | 1 |
| Nakashima, K | 1 |
| Fiala, S | 1 |
| Pragani, B | 1 |
| Reuber, MD | 1 |
| Onoé, T | 4 |
| Kaneko, A | 3 |
| Dempo, K | 3 |
| Ogawa, K | 2 |
| Minase, T | 1 |
| Fujita, S | 1 |
| Ishizuka, H | 1 |
| Kamimura, N | 1 |
| Kaneda, H | 1 |
| Ariga, K | 1 |
| Ichihara, A | 1 |
| Boss, JH | 1 |
| Zajicek, G | 1 |
| Okon, E | 1 |
| Rosenmann, E | 1 |
| Smith, CJ | 1 |
| Kelleher, PC | 1 |
| Carruthers, C | 2 |
| Baumler, A | 2 |
| Neilson, A | 2 |
| Tchipysheva, TA | 1 |
| Guelstein, VI | 1 |
| Bannikov, GA | 1 |
| Stratil, P | 1 |
| Dolezalová, V | 1 |
| Nĕmecek, R | 1 |
| Simícková, M | 1 |
| Enomoto, K | 1 |
| Mori, M | 1 |
| Lafond, MG | 1 |
| Calabrese, EJ | 1 |
| Labuc, GE | 1 |
| Blunck, JM | 2 |
| Katayama, S | 1 |
| Yamaguchi, I | 1 |
| Nakano, Y | 1 |
| Fukuda, M | 1 |
| Kuroda, K | 1 |
| Akao, M | 1 |
| Harris, CL | 1 |
| Kerns, FT | 1 |
| St Clair, W | 1 |
| Pressman, D | 1 |
| Yoshida, Y | 2 |
| Yokoyama, S | 1 |
| Lambooy, JP | 1 |
| Itabashi, M | 1 |
| Mochizuki, Y | 1 |
| Tsukada, H | 1 |
| Reddy, KP | 1 |
| Buschmann, RJ | 1 |
| Chomet, B | 1 |
| Chisaka, N | 1 |
| Sato, K | 1 |
| Takaya, S | 1 |
| Imai, F | 1 |
| Hatayama, I | 1 |
| Ito, N | 1 |
| Toh, BH | 1 |
| Cauchi, MN | 1 |
| Cook, PC | 1 |
| Muller, HK | 1 |
| Boyd, H | 1 |
| Martin, TJ | 1 |
| Ricco, JB | 1 |
| Franco, D | 1 |
| Morin, J | 1 |
| Decloître, F | 1 |
| Bismuth, H | 1 |
| Kobliakov, VA | 1 |
| Riabykh, TP | 1 |
| Masuda, H | 1 |
| Shichijo, S | 1 |
| Takeuchi, M | 1 |
| Crowther, CE | 1 |
| Farber, E | 1 |
| Solt, D | 1 |
| Cameron, R | 1 |
| Laishes, B | 1 |
| Medline, A | 1 |
| Mack, DO | 1 |
| Lewis, EM | 1 |
| Butler, EM | 1 |
| Archer, WH | 1 |
| Smith, LD | 1 |
2 reviews available for methyldimethylaminoazobenzene and Experimental Neoplasms
| Article | Year |
|---|---|
Properties of incomplete carcinogens and promoters in hepatocarcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; Hepate | 1982 |
Is the selenium drinking water standard justified?
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adolescent; Animals; Antineoplastic Agents; Carcinogens; Chromosom | 1979 |
48 other studies available for methyldimethylaminoazobenzene and Experimental Neoplasms
| Article | Year |
|---|---|
3-Methylcholanthrene as an inhibitor of hepatic cancer induced by 3'-methyl-4-dimethylaminoazobenzene in the diet of the rat: a determination of the time relationships.
Topics: Animals; Bile Duct Neoplasms; Diet; Liver Neoplasms; Methylcholanthrene; Methyldimethylaminoazobenze | 1953 |
HISTOCHEMICAL STUDIES OF CHOLESTEROL IN THE SUPRARENAL CORTEX OF RATS IN LIVER CANCEROGENESIS INDUCED BY 3-METHYL 4-DIMETHYLAMINOAZOBENZENE.
Topics: Adrenal Glands; Cholesterol; Histocytochemistry; Lipid Metabolism; Liver Neoplasms; Methyldimethylam | 1964 |
ANALYSIS OF THE LIVERS AND TUMORS FOR FOURTEEN TRACE ELEMENTS OF RATS FED 3'-METHYL-4-DIMETHYLAMINOAZOBENZENE (3'-ME-DAB).
Topics: Carcinoma; Carcinoma, Hepatocellular; Copper; Dietary Proteins; Histocytochemistry; Iron; Liver; Liv | 1964 |
Liver tumor inhibition and adrenal histologic responses in rats to which 3'-methyl-4-dimethylaminoazobenzene and 20-methylcholanthrene were simultaneously administered.
Topics: Animals; Liver Neoplasms; Methylcholanthrene; Methyldimethylaminoazobenzene; Neoplasms, Experimental | 1952 |
Serum and liver glycylproline dipeptidyl aminopeptidase activity in rats with experimental hepatic cancer.
Topics: Aminopeptidases; Animals; Dipeptides; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Male; Methy | 1980 |
Glucose-6-phosphate dehydrogenase and gama-glutamyltranspeptidase activities in the liver during chemically induced hepatocarcinogenesis in rats and mice.
Topics: Animals; Diet; Diethylnitrosamine; gamma-Glutamyltransferase; Glucosephosphate Dehydrogenase; Liver; | 1981 |
Early events during liver carcinogenesis involving two carcinogen:protein complexes.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Carcinoma, Hepatocellular; Cytosol; Ethionine; Female; | 1981 |
Glycosaminoglycans in 3'-methyl-4-dimethylaminoazobenzene-induced rat hepatic cancer.
Topics: Adenoma, Bile Duct; Animals; Glycosaminoglycans; Liver; Liver Neoplasms, Experimental; Male; Methyld | 1982 |
Induction of tumors in transplacental or neonatal mice administered 3'-methyl-4-dimethylaminoazobenzene or 4-aminoazobenzene.
Topics: Adenoma; Animals; Azo Compounds; Carcinogens; Female; Liver Neoplasms; Lung Neoplasms; Lymphoma; Mat | 1983 |
Localization of fetal aldolases during early stages of azo-dye hepatocarcinogenesis in rat.
Topics: Animals; Fluorescent Antibody Technique; Fructose-Bisphosphate Aldolase; Immunoenzyme Techniques; Is | 1980 |
Effect of retinoic acid, butylated hydroxytoluene, selenium and sorbic acid on azo-dye hepatocarcinogenesis.
Topics: Animals; Drug Interactions; Fatty Acids, Unsaturated; Liver Neoplasms; Male; Methyldimethylaminoazob | 1980 |
[Changes of 67Ga-citrate accumulation in the rat liver during feeding with chemical carcinogen 3'-methyl-4-dimethylaminoazobenzene (author's transl)].
Topics: Animals; Gallium Radioisotopes; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplas | 1982 |
A comparative study of ultrastructural changes induced by chronic treatment with 3'-methyl-4-dimethylaminoazobenzene and the non-carcinogen 3'-methyl-4-diethylaminoazobenzene in the rat hepatocyte.
Topics: Animals; Diet; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; | 1982 |
Effect of 3'-methyl-4-dimethylaminoazobenzene in the induction of malignant transformation and of 8-azaguanine-resistant mutations and chromosomal aberrations in a diploid clone derived from normal rat liver cells in culture.
Topics: Animals; Azaguanine; Cell Transformation, Neoplastic; Chromosome Aberrations; Clone Cells; Drug Resi | 1982 |
Protein kinases of rat liver during hepatocarcinogenesis induced by an azo dye.
Topics: Animals; Chromatography, DEAE-Cellulose; Electrophoresis, Cellulose Acetate; Liver Neoplasms; Male; | 1983 |
Changes in th circadian rhythm of ornithine decarboxylase in rat liver during chemical hepatocarcinogenesis.
Topics: 1-Naphthylisothiocyanate; Animals; Bile Ducts; Carboxy-Lyases; Carcinogens; Circadian Rhythm; Hyperp | 1981 |
Effect of diazepam on hepatocarcinogenesis in the rat.
Topics: Animals; Diazepam; Diet; Drug Interactions; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenz | 1982 |
Change in intracellular pH of rat liver during azo-dye carcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Growth; Hydrogen-Ion Concentra | 1976 |
Higher transpeptidation activity and broad acceptor specificity of gamma-glutamyltransferases of tumors.
Topics: Amino Acids; Animals; Animals, Newborn; Carcinoma, Hepatocellular; Cattle; Enzyme Activation; Female | 1976 |
Inhibition of 3'-methyl-4-dimethylaminoazobenezene-induced hepatocarcinogenesis by portacaval shunt.
Topics: Animals; Biotransformation; Carcinoma, Hepatocellular; gamma-Glutamyltransferase; Glutathione; Hyper | 1978 |
Alpha-Fetoprotein and early histological changes of hepatic tissue in DAB-hepatocarcinogenesis.
Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Fetal Proteins; Liver; Liver Neoplasms; Meth | 1975 |
The alpha-fetoprotein-producing cells in the early stage of the experimental liver cancer.
Topics: alpha-Fetoproteins; Animals; Fetal Proteins; Fluorescent Antibody Technique; Liver Neoplasms; Male; | 1975 |
Isozyme patterns of branched-chain amino acid transaminase during cellular differentiation and carcinogenesis.
Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Cell Differentiation; Cell Transformation, N | 1975 |
Excretion of alpha-foetoprotein in the urine of rats during exposure to 3'-methyl-4-dimethylaminoazobenzene.
Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Female; Liver Neoplasms; Methyldimethylamino | 1977 |
Induction of hepatomas secreting large amounts of alpha-fetoprotein.
Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Methyldimethylaminoazobenze | 1977 |
A distinctive antigen present in liver carcinomas induced by 3'-methyl-p-dimethylaminoazobenzene.
Topics: Adenoma, Bile Duct; alpha-Fetoproteins; Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Carcinoma | 1977 |
alpha-fetoprotein-containing cells in the early stages of liver carcinogenesis induced by 3'-methyl-4-dimethyl-aminoazobenzene and 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Liver; Liver Neoplasms; Methyldimethylaminoazobe | 1977 |
Relationship between alpha-fetoprotein positive cells and precancerous lesions in rat liver during 3'-methyl-4-dimethylaminoazobenzene carcinogenesis.
Topics: alpha-Fetoproteins; Animals; Cell Transformation, Neoplastic; Female; Fluorescent Antibody Technique | 1979 |
Histopathological and ultrastructural study on extramedullary hematopoietic foci in early stage of 3'-methyl-4-(dimethylamino)azobenzene hepatocarcinogenesis.
Topics: Animals; Cytoplasm; Hematopoietic System; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzen | 1978 |
Inhibition of 3'-methyl-4-dimethylaminoazobenzene (3'MeDAB)-induced hepatocarcinogenesis in the rat: chloramphenicol inhibits N,N-dimethylaniline N-oxidase and in vitro binding of [3H]3'MeDAB to protein but not to RNA.
Topics: Aniline Compounds; Animals; Chloramphenicol; Diet; In Vitro Techniques; Liver Neoplasms; Male; Methy | 1979 |
[Proceedings: Differentation of LDH pI isozyme in 3'-MeDAB-induced liver neoplasms].
Topics: Animals; Carcinoma, Hepatocellular; Isoenzymes; L-Lactate Dehydrogenase; Liver Neoplasms; Methyldime | 1975 |
Effect of Capsella bursa-pastoris on liver catalase activity in rats fed 3'-methyl-4-(dimethylamino)azobenzene.
Topics: Animals; Carcinoma, Hepatocellular; Catalase; China; Japan; Liver; Liver Neoplasms; Male; Methyldime | 1975 |
RNA sulfurtransferase activity in rat liver and chemically induced hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Histocytochemistry; Liver; Liver Neoplasms; Male; Methyldimethyl | 1975 |
Binding of the azocarcinogen 3'-methyl-p-dimethylaminoazobenzene to cellular components of normal rat liver and azocarcinogen-induced hepatomas.
Topics: Adenoma, Bile Duct; Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Membrane; Cell Nucleus; | 1975 |
Some properties and electrophoretic patterns of rat liver esterases in relation to hepatocarcinogenesis by 3'-methyl-4-(dimethylamino) azobenzene.
Topics: Acetates; Animals; Carcinoma, Hepatocellular; Cholinesterases; Cysteine; Electrophoresis, Cellulose | 1976 |
Influence of riboflavin antagonists on azo dye hepatoma induction in the rat.
Topics: Animals; Carcinoma, Hepatocellular; Flavins; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; N | 1976 |
Changes in peroxisomes in preneoplastic liver of rats induced by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Carcinoma, Hepatocellular; Catalase; Cell Differentiation; Clofibrate; Enzyme Induction; Hy | 1977 |
Cholangiocarcinomas induced by feeding 3'-methyl-4-dimethylaminoazobenzene to rats. Histopathology and ultrastructure.
Topics: Adenoma, Bile Duct; Animals; Basement Membrane; Cell Membrane; Cell Nucleus; Diet; Golgi Apparatus; | 1977 |
Appearance of intestinal type of tumor cells in hepatoma tissue induced by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Cytoplasmic Granules; Intestines; Isoenzym | 1978 |
Different deviation patterns of carbohydrate-metabolizing enzymes in primary rat hepatomas induced by different chemical carcinogens.
Topics: 2-Acetylaminofluorene; Animals; Carbohydrate Metabolism; Carcinogens; Carcinoma, Hepatocellular; Cel | 1978 |
Increased expression of actin-like contractile protein in preneoplastic and neoplastic lesions in rat liver.
Topics: Actins; Animals; Contractile Proteins; Fluorescent Antibody Technique; Hepatectomy; Liver Neoplasms; | 1977 |
The effect of propranolol on induction of rat liver tumors by a chemical carcinogen.
Topics: Animals; Diet; Drug Interactions; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, E | 1977 |
Modifications of 3'-methyl-4-dimethylaminoazobenzene carcinogenesis of rat liver and carcinogen metabolism by portacaval anastomosis.
Topics: Animals; Body Weight; Inactivation, Metabolic; Liver; Liver Neoplasms; Male; Methyldimethylaminoazob | 1977 |
[Respiration of the cells and isolated mitochondria of the rat liver in the early stages of hepatocarcinogenesis].
Topics: 2-Acetylaminofluorene; Animals; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Mitochondria, | 1977 |
Glycopeptide and glycosaminoglycans in the process of hepatic cancer induced by 3'-methyl-DAB.
Topics: Animals; Glycopeptides; Glycosaminoglycans; Hexosamines; Hexoses; Liver Neoplasms; Male; Methyldimet | 1978 |
Enhancement of azo dye carcinogenesis by dietary sodium sulphate.
Topics: Acetanilides; Animals; Azo Compounds; Body Weight; Diet; Drug Synergism; Liver; Liver Cirrhosis; Liv | 1975 |
Newer insights into the pathogenesis of liver cancer.
Topics: Aflatoxins; Animals; Cell Division; Cell Transformation, Neoplastic; Diethylnitrosamine; Dimethylnit | 1977 |
A comparison of succinyladenylate lyase activity and serum sialic acid as markers of malignancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenosine Triphosphatases; Adenylosuccinate Lyase; Animals; Clinic | 1985 |