methyldimethylaminoazobenzene has been researched along with Experimental Hepatoma in 161 studies
Methyldimethylaminoazobenzene: A very potent liver carcinogen.
3-methyl-4'-dimethylaminoazobenzene : A member of the class of azobenzenes that is azobenzene in which one of the phenyl groups is substituted at position 3 by a methyl group, while the other is substituted at position 4 by a dimethylamino group. It is a potent liver carcinogen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The resistance to progression to hepatocellular carcinoma is affected solely by Drh2." | 2.42 | Genetic resistance to chemical hepatocarcinogenesis in the DRH rat strain. ( Denda, A; Hiai, H; Higashi, K; Higashi, T, 2004) |
| "Time-course studies on the microsomal cytochrome P450s in the livers of carcinogen-resistant (DRH) and sensitive (Donryu) rats were carried out during a long-term administration of 3'-methyl-4-dimethylaminoazobenzene (3'-Me-DAB)." | 1.30 | Studies on the microsomal cytochrome P450s in the livers of carcinogen-resistant and sensitive rats during long-term administration of 3'-methyl-4-dimethylaminoazobenzene. ( Fukamachi, Y; Higashi, K; Hirano, T; Kawamoto, T; Yamamura, K; Yan, Y; Yang, M, 1997) |
| " At nodular and post-nodular stages biliary excretion of radioactive metabolites was decreased, although hepatic content of radioactivity was similar to controls not dosed with AAF." | 1.28 | Protein binding, nuclear translocation and biliary secretion of metabolites of 3'-methyl-N,N-dimethyl-4-aminoazobenzene during hepatocarcinogenesis in rats. ( Bhargava, MM; Levine, WG; Srinivasan, K, 1991) |
| "The long-term administration of 3'-methyl-4-dimethylaminoazobenzene (3'-Me-DAB) to rats causes marked changes in concentrations and synthesis of nucleic acids in the liver." | 1.27 | Biosynthesis of nuclear RNAs during 3'-methyl-4-dimethyl-aminoazobenzene hepatocarcinogenesis and in transplantable rat hepatomas. ( Dolezalová, V; Simícková, M, 1983) |
| " Drug resistance was not induced by chronic administration of the tumor promoters phenobarbital, choline-deficient diet, phorbol, nor with 2,3,7,8-tetrachlorodibenzo-p-dioxin, but was induced to a variable extent by three hepatotoxins (ethanol, methotrexate, carbon tetrachloride)." | 1.27 | Pleiotropic drug resistance in hepatocytes induced by carcinogens administered to rats. ( Carr, BI, 1987) |
| "025% 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) for two weeks combined with partial hepatectomy at the end of the first week and followed by long-term treatment with phenobarbital (PB) or 3'-methyl-4-dimethylaminoazobenzene (3'-Me-DAB) from week 3 to week 86 resulted in dose-dependent development of liver and thyroid neoplastic and preneoplastic lesions." | 1.27 | Dose-dependent induction of liver and thyroid neoplastic lesions by short-term administration of 2-amino-3-methylimidazo[4,5-f]quinoline combined with partial hepatectomy followed by phenobarbital or low dose 3'-methyl-4-dimethylaminoazobenzene promotion. ( Asamoto, M; Inoue, T; Ito, N; Nagao, M; Ogiso, T; Tsuda, H, 1988) |
| "MeCh both reduced the incidence of hepatic neoplasms induced by 3'-MeDAB and delayed their development." | 1.26 | 3-Methylcholanthrene-inhibition of hepatocarcinogenesis in the rat due to 3'-methyl-4-dimethylaminoazobenzene or 2-acetylamino-fluorene: a comparative study. ( Flaks, A; Flaks, B, 1982) |
| "Uracil incorporation was found to be gradually elevated during the early stage (about 2 weeks) of the carcinogenesis, although not in the normal rat liver homogenates contacted with the carcinogen for a short hours, and the elevated uptake was maintained until tumor induction." | 1.26 | Elevation of the salvage synthesis of ribonucleic acid in the rat liver during the induction of hepatoma with 3'-methyl-4-(dimethylamino)azobenzene. ( Fujisawa, M; Takeda, T; Tamemasa, O; Tezuka, M, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 103 (63.98) | 18.7374 |
| 1990's | 45 (27.95) | 18.2507 |
| 2000's | 13 (8.07) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, Y | 1 |
| Deng, WG | 1 |
| Li, YL | 1 |
| Sugiyama, T | 3 |
| Liu, H | 2 |
| Nobumoto, K | 1 |
| Yamada, Y | 1 |
| Higashi, K | 11 |
| Hiai, H | 5 |
| PETASNICK, JP | 1 |
| BROWN, RR | 1 |
| PRICE, JM | 1 |
| Nakamatsu, K | 1 |
| Nishimura, Y | 1 |
| Suzuki, M | 1 |
| Kanamori, S | 1 |
| Maenishi, O | 1 |
| Yasuda, Y | 1 |
| Denda, A | 3 |
| Higashi, T | 7 |
| Sano, T | 1 |
| Kagawa, M | 1 |
| Okuno, M | 2 |
| Ishibashi, N | 1 |
| Hashimoto, M | 2 |
| Yamamoto, M | 2 |
| Suzuki, R | 1 |
| Kohno, H | 1 |
| Matsushima-Nishiwaki, R | 2 |
| Takano, Y | 1 |
| Tsurumi, H | 2 |
| Kojima, S | 1 |
| Friedman, SL | 1 |
| Moriwaki, H | 4 |
| Tanaka, T | 4 |
| Merkulova, TI | 1 |
| Kropachev, KY | 1 |
| Timofeeva, OA | 1 |
| Vasiliev, GV | 1 |
| Levashova, ZB | 1 |
| Ilnitskaya, SI | 1 |
| Kobzev, VF | 1 |
| Pakharukova, MY | 1 |
| Bryzgalov, LO | 1 |
| Kaledin, VI | 1 |
| Chen, QR | 1 |
| Xiang, J | 1 |
| Liao, B | 1 |
| Liu, QB | 1 |
| Che, LH | 1 |
| Xue, L | 2 |
| Zhao, GQ | 1 |
| Ando, N | 1 |
| Shimizu, M | 1 |
| Fiala, S | 1 |
| Trout, EC | 1 |
| Ostrander, H | 1 |
| Fiala, AE | 1 |
| Kitagawa, T | 8 |
| Kayano, T | 2 |
| Mikami, K | 1 |
| Watanabe, R | 1 |
| Sugano, H | 3 |
| Torii, M | 1 |
| Kanai, K | 1 |
| Watabe, H | 1 |
| Oka, H | 1 |
| Oda, T | 1 |
| Schmidt, WN | 5 |
| Gronert, BJ | 3 |
| Page, DL | 4 |
| Briggs, RC | 2 |
| Hnilica, LS | 5 |
| Schwartz, CE | 2 |
| Gabryelak, T | 1 |
| Smith, CJ | 1 |
| Taylor, JM | 1 |
| Chiu, JF | 4 |
| McKusick, KB | 2 |
| Taga, H | 5 |
| Simícková, M | 3 |
| Dolezalová, V | 3 |
| Iwai, M | 4 |
| Dempo, K | 3 |
| Sasaki, M | 1 |
| Kaku, T | 1 |
| Satoh, M | 1 |
| Oyamada, M | 1 |
| Mori, M | 3 |
| Stratil, P | 1 |
| Kocent, A | 1 |
| Nĕmecek, R | 2 |
| French, BT | 1 |
| Hanausek-Walaszek, M | 1 |
| Walaszek, Z | 1 |
| Schumm, DE | 1 |
| Webb, TE | 1 |
| Sato, K | 2 |
| Hatayama, I | 2 |
| Hoshino, K | 1 |
| Imai, F | 1 |
| Tsuchida, S | 1 |
| Sato, T | 3 |
| Nishimura, K | 1 |
| Tatematsu, M | 1 |
| Ito, N | 8 |
| Kojima, J | 2 |
| Nakamura, N | 2 |
| Kanatani, M | 2 |
| Akiyama, M | 2 |
| Gotoh, M | 2 |
| Mochizuki, Y | 2 |
| Sawada, N | 2 |
| Tsukada, H | 2 |
| Flaks, B | 3 |
| Flaks, A | 3 |
| Jones, H | 1 |
| Milsom, A | 1 |
| Sato, A | 2 |
| Nakajima, T | 1 |
| Koyama, Y | 1 |
| Shirai, T | 3 |
| Daimon, M | 1 |
| Tsutsumi, K | 1 |
| Sato, J | 3 |
| Tsutsumi, R | 1 |
| Ishikawa, K | 1 |
| Muto, Y | 2 |
| Hino, O | 2 |
| Schmidt, CA | 1 |
| Hoffman, LH | 1 |
| Nomura, K | 2 |
| Miyagi, T | 2 |
| Goto, T | 1 |
| Tsuiki, S | 3 |
| Yanagi, S | 3 |
| Sakamoto, M | 2 |
| Ninomiya, Y | 1 |
| Kamiya, T | 2 |
| Modena, D | 1 |
| Ferioli, ME | 2 |
| Scalabrino, G | 3 |
| Mori, Y | 2 |
| Nagai, H | 1 |
| Hori, T | 1 |
| Niwa, T | 1 |
| Toyoshi, K | 1 |
| Koda, A | 1 |
| Kawada, K | 1 |
| Ojima, A | 1 |
| Morita, S | 1 |
| Kikuchi, S | 1 |
| Nishi, F | 1 |
| Okinaga, T | 1 |
| Moriguchi, Y | 1 |
| Bussaka, Y | 1 |
| Umezaki, N | 1 |
| Yano, K | 1 |
| Ohtake, H | 1 |
| Kojiro, M | 1 |
| Kawasaki, H | 1 |
| Huang, DP | 2 |
| Burkhardt, AL | 1 |
| Cote, G | 1 |
| Ishii, K | 1 |
| Okudaira, M | 1 |
| Shibata, H | 1 |
| Okabe, H | 1 |
| Sidransky, H | 1 |
| Verney, E | 1 |
| Yokoyama, S | 1 |
| Kaneko, A | 1 |
| Chisaka, N | 1 |
| Onoe, T | 2 |
| Furukawa, K | 1 |
| Takami, H | 1 |
| Abe, O | 1 |
| Knöchel, W | 1 |
| Patel, NT | 1 |
| Holoubek, V | 1 |
| Enomoto, K | 1 |
| Kashiwagi, T | 1 |
| Tohjoh, F | 1 |
| Tarui, Y | 1 |
| Koizumi, K | 1 |
| Tamiya-Koizumi, K | 1 |
| Fujii, T | 1 |
| Okuda, J | 1 |
| Kojima, K | 1 |
| Yamamoto, N | 1 |
| Takahashi, M | 2 |
| Fujii, J | 1 |
| Miyoshi, E | 2 |
| Hoshi, A | 1 |
| Taniguchi, N | 3 |
| Yamamoto, R | 4 |
| Iishi, H | 3 |
| Tatsuta, M | 4 |
| Yamamoto, T | 1 |
| Koike, K | 1 |
| Kanda, Y | 1 |
| Miyake, A | 1 |
| Tsuji, M | 3 |
| Terada, N | 4 |
| Sarkar, A | 1 |
| Mukherjee, B | 1 |
| Chatterjee, M | 1 |
| Kashiwadani, M | 2 |
| Kitagawa, Y | 1 |
| Kashima, K | 1 |
| Ibata, Y | 3 |
| Yasuda, K | 1 |
| Ikuyama, T | 1 |
| Watanabe, T | 1 |
| Minegishi, Y | 1 |
| Osanai, H | 1 |
| Nomura, M | 3 |
| Nakachiyama, M | 1 |
| Hida, T | 1 |
| Ohtaki, Y | 3 |
| Sudo, K | 2 |
| Aizawa, T | 1 |
| Aburada, M | 2 |
| Miyamoto, KI | 1 |
| Liao, D | 1 |
| Porsch-Hällström, I | 1 |
| Gustafsson, JA | 1 |
| Blanck, A | 1 |
| Horikawa, S | 1 |
| Kobayashi, Y | 1 |
| Terashima, H | 1 |
| Wada, K | 1 |
| Tsukada, K | 1 |
| Hirokawa S [corrected to Horikawa, S] | 1 |
| de Camargo, JL | 1 |
| Tsuda, H | 6 |
| Asamoto, M | 2 |
| Tagawa, Y | 1 |
| Wada, S | 1 |
| Nagase, S | 2 |
| Miyamoto, K | 2 |
| Hiramatsu, K | 1 |
| Kanitani, M | 1 |
| Lorenzini, EC | 1 |
| Buccellato, FR | 1 |
| Shimpo, K | 1 |
| Takahashi, H | 1 |
| Hibino, T | 1 |
| Kawai, K | 2 |
| Kimura, C | 1 |
| Nagatsu, T | 1 |
| Fujita, K | 1 |
| Saito, S | 1 |
| Hashimoto, N | 1 |
| Tokita, K | 1 |
| Toyoda, M | 1 |
| Suzuki, Y | 4 |
| Goldstein, BJ | 1 |
| Suzuki, H | 1 |
| Makino, H | 1 |
| Saito, Y | 1 |
| Yang, M | 1 |
| Yamamura, K | 2 |
| Yan, Y | 6 |
| Fukamachi, Y | 4 |
| Hirano, T | 3 |
| Kawamoto, T | 1 |
| Noda, K | 1 |
| Uozumi, N | 1 |
| Gao, CX | 1 |
| Suzuki, K | 1 |
| Hayashi, N | 2 |
| Hori, M | 1 |
| Ogasawara, H | 1 |
| Hiramoto, J | 1 |
| Shirahama, K | 1 |
| Furusaka, A | 1 |
| Hiyane, S | 1 |
| Nakada, T | 1 |
| Nagayama, K | 1 |
| Abe, T | 4 |
| Gotoh, S | 3 |
| Sugiura, T | 2 |
| Ichiba, M | 1 |
| Kitayama, W | 1 |
| Konishi, Y | 3 |
| Miura, M | 1 |
| Ikemura, K | 1 |
| Mise-Omata, S | 1 |
| Yamashita, U | 1 |
| Yamashiro, K | 2 |
| Ohtsuki, M | 1 |
| Hamada, Y | 1 |
| Todaka, N | 1 |
| Sakai, A | 1 |
| Tsurudome, Y | 1 |
| Ootsuyama, Y | 1 |
| Kido, R | 1 |
| Kasai, H | 1 |
| Wen, J | 1 |
| Zhao, G | 1 |
| Zeng, ZZ | 1 |
| Higashi, S | 1 |
| Onishi, S | 1 |
| Ueno, H | 1 |
| Mechitov, VI | 1 |
| Adler, VV | 1 |
| Shapot, VS | 1 |
| Abraham-Inpijn, L | 1 |
| Pitot, HC | 1 |
| Miller, EC | 1 |
| Miller, JA | 1 |
| Smith, LD | 2 |
| Emerson, RL | 1 |
| Nixon, LK | 1 |
| Kodama, M | 1 |
| Ohki, T | 1 |
| Saitô, H | 1 |
| Nagata, C | 1 |
| Tagashira, Y | 1 |
| Tamemasa, O | 1 |
| Tezuka, M | 1 |
| Fujisawa, M | 1 |
| Takeda, T | 1 |
| Nagarajan, B | 1 |
| Sukumar, S | 1 |
| Chai, KJ | 3 |
| Kim, JS | 1 |
| Lee, HK | 1 |
| Minote, H | 1 |
| Inoue, K | 1 |
| Higashide, S | 1 |
| Tobe, T | 1 |
| Takeuchi, E | 1 |
| Mori, C | 1 |
| Shiota, K | 1 |
| Yang, L | 1 |
| Tsutsui, S | 1 |
| Aruna, K | 1 |
| Sivaramakrishnan, VM | 1 |
| Xu, HY | 1 |
| Ohkusa, A | 1 |
| Yoshioka, H | 1 |
| Okafuji, T | 1 |
| Ishida, O | 1 |
| Fritz-Zieroth, B | 1 |
| Sakamoto, S | 2 |
| Hirai, H | 4 |
| Uchikoshi, T | 2 |
| Sunaga, T | 3 |
| Endo, Y | 3 |
| Kuwa, K | 2 |
| Kudo, H | 2 |
| Kawachi, Y | 2 |
| Kasahara, N | 2 |
| Dong, JM | 1 |
| Kilianska, Z | 1 |
| Fukuda, K | 1 |
| Lertprasertsuke, N | 2 |
| Shinoda, M | 2 |
| Takekoshi, S | 2 |
| Yoshimura, S | 1 |
| Watanabe, K | 2 |
| Ohkawa, K | 1 |
| Hatano, T | 1 |
| Takizawa, N | 1 |
| Yamada, K | 2 |
| Takada, K | 1 |
| Aida, Y | 1 |
| Maeyama, S | 1 |
| Takakuwa, T | 1 |
| Srinivasan, K | 1 |
| Levine, WG | 1 |
| Bhargava, MM | 1 |
| Su, WC | 1 |
| Sun, TP | 1 |
| Wu, FY | 1 |
| Wakusawa, S | 1 |
| Sanae, F | 1 |
| Sakai, R | 1 |
| Takeda, S | 1 |
| Fujii, Y | 1 |
| Karaki, Y | 1 |
| Munakata, S | 1 |
| Saeki, T | 1 |
| Hirota, S | 1 |
| Fujimaki, M | 1 |
| Tsutsumi, Y | 1 |
| Yamamoto, Y | 1 |
| Niki, E | 1 |
| Mack, DO | 1 |
| Reed, VL | 1 |
| Kato, T | 1 |
| Okamoto, R | 1 |
| Kim, YS | 4 |
| Paik, EM | 1 |
| Lee, MS | 1 |
| Kim, KS | 2 |
| Ahn, YH | 2 |
| Scoazec, JY | 3 |
| Hassan, N | 1 |
| Feldmann, G | 3 |
| Shibasaki, M | 1 |
| Sanjo, K | 1 |
| Bandai, Y | 1 |
| Imamura, H | 1 |
| Nomura, Y | 1 |
| Hirata, M | 1 |
| Chou, S | 1 |
| Minagawa, M | 1 |
| Ohashi, K | 1 |
| McKusick, K | 1 |
| Lamas, E | 2 |
| Schweighoffer, F | 1 |
| Van Els, C | 1 |
| Bachner, L | 1 |
| Márie, J | 1 |
| Kahn, A | 2 |
| Kamata, Y | 1 |
| Hasegawa, R | 3 |
| Kurata, Y | 1 |
| Masuda, A | 1 |
| Okuno, T | 1 |
| Okanoue, T | 1 |
| Takino, T | 2 |
| Kadofuku, T | 1 |
| Iino, S | 1 |
| Sugiura, M | 1 |
| Futagawa, S | 1 |
| Kohnoe, S | 1 |
| Maehara, Y | 1 |
| Endo, H | 2 |
| Zhang, JS | 1 |
| Moreau, A | 2 |
| Bernuau, D | 1 |
| Scott, RJ | 1 |
| Chakraborty, S | 1 |
| Sell, S | 1 |
| Hunt, JM | 1 |
| Dunsford, HA | 1 |
| Mutai, M | 1 |
| Imaida, K | 2 |
| Yamaguchi, S | 1 |
| Yamashita, M | 1 |
| Hiasa, Y | 1 |
| Kuroda, K | 3 |
| Akao, M | 3 |
| Ebisuno, S | 1 |
| Isohashi, F | 1 |
| Nakanishi, Y | 1 |
| Sakamoto, Y | 3 |
| Terayama, H | 1 |
| Shimizu, N | 1 |
| Fukuzumi, R | 1 |
| Hosoda, K | 1 |
| Hirose, K | 1 |
| Hirose, M | 1 |
| Fukui, R | 1 |
| Sekiyama, M | 1 |
| Yoshimoto, F | 2 |
| Tateishi, N | 2 |
| Miyazaki, M | 2 |
| Handa, Y | 1 |
| Carr, BI | 1 |
| Wahid, S | 1 |
| Nishikawa, A | 1 |
| Fujii, S | 1 |
| Kittler, JM | 1 |
| Meisler, NT | 1 |
| Thanassi, JW | 1 |
| Tsai, C | 1 |
| Kusumoto, Y | 1 |
| Harada, R | 1 |
| Shima, M | 1 |
| Nakata, K | 1 |
| Kono, K | 1 |
| Ishii, N | 1 |
| Koji, T | 1 |
| Nagataki, S | 1 |
| Makino, R | 1 |
| Sato, S | 1 |
| Esumi, H | 1 |
| Negishi, C | 1 |
| Takano, M | 1 |
| Sugimura, T | 1 |
| Tanaka, H | 1 |
| Guillouzo, A | 1 |
| Mori, H | 1 |
| Sugie, S | 1 |
| Kuniyasu, T | 1 |
| Iwata, H | 1 |
| Ni-i, H | 1 |
| Nishiwaki, A | 1 |
| Kim, SN | 1 |
| Winton, DJ | 1 |
| Ogiso, T | 2 |
| Inoue, T | 1 |
| Nagao, M | 1 |
| Koseki, M | 1 |
| Medvedev, ZA | 1 |
| Crowne, HM | 1 |
| Medvedeva, MN | 1 |
| Ueno, T | 1 |
| Takahashi, K | 1 |
| Matsuguchi, T | 1 |
| Ikejiri, K | 1 |
| Maurice, M | 1 |
| Xu, YD | 1 |
| Ninomiya, M | 1 |
| Seto, T | 1 |
| Makino, Y | 1 |
| Yamamoto, K | 1 |
| Tsuji, T | 1 |
| Hahm, KS | 1 |
| Lee, NJ | 1 |
| Tamura, S | 1 |
| Kikuchi, K | 1 |
| Hirai, R | 1 |
| Terao, K | 1 |
| Masui, T | 1 |
| Tsukidate, K | 1 |
| Taki, T | 1 |
| Katayama, K | 1 |
| Sorof, S | 1 |
| Custer, RP | 1 |
| Cho, MY | 1 |
| Takahashi, S | 1 |
| Hasuike, A | 1 |
| Kumazawa, K | 1 |
| Nakano, T | 1 |
| Masuda, S | 1 |
| Nishii, T | 1 |
| Takamisawa, I | 1 |
| Sugioka, Y | 1 |
| Fujii-Kuriyama, Y | 1 |
| Muramatsu, M | 1 |
| Cote, GJ | 1 |
| Lastra, BA | 1 |
| Cook, JR | 1 |
| Ashby, J | 1 |
| Elliott, BM | 1 |
| Keen, W | 1 |
| Riley, E | 1 |
| Aquino, TM | 1 |
| Porta, EA | 1 |
| Sablan, HM | 1 |
| Dorado, RD | 1 |
1 review available for methyldimethylaminoazobenzene and Experimental Hepatoma
| Article | Year |
|---|---|
Genetic resistance to chemical hepatocarcinogenesis in the DRH rat strain.
Topics: Animals; Carcinoma, Hepatocellular; DNA Adducts; Hepatectomy; Hepatocytes; Immunity, Innate; Liver N | 2004 |
160 other studies available for methyldimethylaminoazobenzene and Experimental Hepatoma
| Article | Year |
|---|---|
[Quantitative analysis of p53 and related genes mRNA in rat hepatocarcinogenesis induced by 3'-Me-DAB].
Topics: Actins; Albumins; alpha-Fetoproteins; Animals; Genes, p53; Glutathione Transferase; Liver; Liver Neo | 2003 |
Modulation of genetic resistance to hepatocarcinogenesis in DRH rats by partial hepatectomy.
Topics: Animals; Carcinogens; Cell Division; Genetic Predisposition to Disease; Hepatectomy; Liver Neoplasms | 2003 |
The effect of feeding 3'-methyl-4-dimethylaminoazobenzene on tryptophan metabolism of rats.
Topics: Animals; Carcinogens; Liver; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; p-Dimethy | 1961 |
Erythropoietin/erythropoietin-receptor system as an angiogenic factor in chemically induced murine hepatic tumors.
Topics: Animals; Capillaries; Erythropoietin; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Li | 2004 |
Role of resistant Drh1 locus in chemical carcinogen-induced hepatocarcinogenesis in rats: analysis with a speed congenic strain.
Topics: Administration, Oral; Animals; Apoptosis; Carcinogens; Cell Cycle; Cell Transformation, Neoplastic; | 2005 |
Prevention of rat hepatocarcinogenesis by acyclic retinoid is accompanied by reduction in emergence of both TGF-alpha-expressing oval-like cells and activated hepatic stellate cells.
Topics: Actins; Adenoma; Animals; Antineoplastic Agents; Carcinoma; Disease Models, Animal; Disease Progress | 2005 |
Species-specific effects of the hepatocarcinogens 3'-methyl-4-dimethyl-aminoazobenzene and ortho-aminoazotoluene in mouse and rat liver.
Topics: Animals; Carcinogens; Cell Nucleus; Diethylnitrosamine; Enzyme Induction; Glucocorticoids; Hepatocyt | 2005 |
[Evolutive characters of oval cells in experimental hepatocarcinogenesis].
Topics: Animals; Carcinoma, Hepatocellular; Cholangiocarcinoma; Hepatocytes; Immunohistochemistry; Liver; Li | 2007 |
Expression of retinoid X receptor alpha is decreased in 3'-methyl-4-dimethylaminoazobenzene-induced hepatocellular carcinoma in rats.
Topics: Adenoma; Animals; beta Catenin; Blotting, Western; Carcinoma, Hepatocellular; Cell Nucleus; Cyclin D | 2007 |
gamma-Glutamyltransferase and the inhibition of azo dye-produced neoplasia by concomitant administration of disulfiram.
Topics: Animals; Disulfiram; gamma-Glutamyltransferase; Hyperplasia; Liver; Liver Neoplasms, Experimental; M | 1980 |
Promotion of hepatocarcinogenesis in vivo and in vitro.
Topics: Animals; Epidermal Growth Factor; gamma-Glutamyltransferase; In Vitro Techniques; Liver; Liver Neopl | 1983 |
Effect of BCG on hepatocarcinogenesis of the rat induced by 3'-methyl-4-(dimethylamino)azobenzene.
Topics: alpha-Fetoproteins; Animals; Immunity, Cellular; Liver Neoplasms, Experimental; Male; Methyldimethyl | 1980 |
Antigenic changes in nonhistone proteins during azo dye hepatocarcinogenesis.
Topics: Animals; Cell Nucleus; Chromatin; Chromosomal Proteins, Non-Histone; Epitopes; Liver; Liver Neoplasm | 1982 |
The expression of alpha-fetoprotein and albumin genes in rat liver during chemical carcinogenesis.
Topics: alpha-Fetoproteins; Animals; Kinetics; Liver; Liver Neoplasms, Experimental; Methyldimethylaminoazob | 1982 |
Cytokeratin and nonhistone protein antigenic changes in rat liver during azo dye but not hepatotoxin feeding.
Topics: 1-Naphthylisothiocyanate; Animals; Antigens; Chromosomal Proteins, Non-Histone; Keratins; Liver; Liv | 1983 |
The effect of active immunization of rats with heterologous alpha-fetoprotein upon hepatocarcinogenesis induced by 3'-methyl-4-dimethylaminoazobenzene.
Topics: alpha-Fetoproteins; Animals; Immune Sera; Immunization; Liver Neoplasms, Experimental; Male; Methyld | 1983 |
Biosynthesis of nuclear RNAs during 3'-methyl-4-dimethyl-aminoazobenzene hepatocarcinogenesis and in transplantable rat hepatomas.
Topics: Animals; Cell Nucleus; DCMP Deaminase; Female; Liver; Liver Neoplasms; Liver Neoplasms, Experimental | 1983 |
Immunocytochemical investigation of alpha-fetoprotein-positive cells in hepatocarcinogenesis and hepatomas induced by 3'-ME-DAB.
Topics: alpha-Fetoproteins; Animals; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Rat | 1983 |
Immunohistochemical studies on alpha-fetoprotein- and albumin-containing cells in the liver during ontogenesis and early stage of 3'-Me-DAB hepatocarcinogenesis.
Topics: Albumins; alpha-Fetoproteins; Animals; Female; Liver; Liver Neoplasms, Experimental; Male; Methyldim | 1983 |
Alpha-fetoprotein (AFP) and alpha 2-macroglobulin (alpha 2-M) as the markers of distinct responses of hepatocytes to carcinogens in the rat: carcinogenesis.
Topics: Acute-Phase Proteins; alpha-Fetoproteins; alpha-Macroglobulins; Animals; Blood Proteins; Carcinogens | 1983 |
Nucleocytoplasmic release of repetitive DNA transcripts in carcinogenesis correlates with a 60 kilodalton cytoplasmic protein.
Topics: Animals; Cell Nucleus; Cytoplasm; Cytosol; Female; Kinetics; Liver; Liver Neoplasms, Experimental; M | 1984 |
Enzyme deviation patterns in primary rat hepatomas induced by sequential administration of two chemically different carcinogens.
Topics: 2-Acetylaminofluorene; Age Factors; Animals; Carcinogens; Diethylnitrosamine; Dose-Response Relation | 1981 |
Glycosaminoglycans in 3'-methyl-4-dimethylaminoazobenzene-induced rat hepatic cancer.
Topics: Adenoma, Bile Duct; Animals; Glycosaminoglycans; Liver; Liver Neoplasms, Experimental; Male; Methyld | 1982 |
Matrical inclusions of peroxisomes induced by clofibrate in preneoplastic hepatocytes of rats fed 3'-methyl-4-dimethyl-aminoazobenzene.
Topics: Animals; Clofibrate; Inclusion Bodies; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobe | 1982 |
Effects of inhibiting hepatocarcinogenesis upon the early fine structural changes induced in rat hepatocytes by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Carcinogens; Liver; Liver Neoplasms, Experimental; Lysosomes; Male; Methylcholanthrene; Met | 1983 |
Chromosomal protein antigens formed in experimental hepatocarcinogenesis by azo dyes.
Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Carcinogens; Chromosomes; Liver; Liver Neoplasms; Liver | 1983 |
Dietary carbohydrate level as a modifying factor of 3'-methyl-4-dimethylaminoazobenzene liver carcinogenesis in rats.
Topics: Animals; Biotransformation; Body Weight; Dietary Carbohydrates; Liver Neoplasms, Experimental; Male; | 1984 |
Changes of aldolase A and B messenger RNA levels in rat liver during azo-dye-induced hepatocarcinogenesis.
Topics: Animals; Fructose-Bisphosphate Aldolase; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Met | 1984 |
Antitumor activity of vitamin A and its derivatives.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Diet; Dose-Response Relationship, | 1984 |
Existence of a practical threshold dose for the hepatocarcinogen 3'-methyl-4-(dimethyl-amino) azobenzene in rat liver.
Topics: Adenosine Triphosphatases; Animals; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoa | 1981 |
Nuclear matrix antigens in azo dye-induced primary rat hepatomas.
Topics: Amino Acids; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Carbohydrates; Carcinoma 256, Walk | 1984 |
Dose-response studies on promoting and anticarcinogenic effects of phenobarbital and DDT in the rat hepatocarcinogenesis.
Topics: Animals; DDT; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Methyldi | 1984 |
Sialidase of rat hepatomas: qualitative and quantitative comparison with rat liver sialidase.
Topics: Animals; Hydrogen-Ion Concentration; Liver; Liver Neoplasms, Experimental; Lysosomes; Male; Methyldi | 1984 |
Decrease in L-type pyruvate kinase activity in rat liver by some promoters of hepatocarcinogenesis.
Topics: Animals; Carbon Tetrachloride Poisoning; Carcinogens; Diethylnitrosamine; Isoenzymes; Isomerism; Liv | 1984 |
Permanent decrease in activity of ornithine decarboxylase antizyme in rat liver during chemical hepatocarcinogenesis.
Topics: Animals; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Ornith | 1983 |
Correlation of deoxycytidylate deaminase activity with cell proliferation during hepatocarcinogenesis and tumour growth in transplantable rat hepatomas.
Topics: Aflatoxins; Animals; Cell Division; DCMP Deaminase; Liver; Liver Neoplasms, Experimental; Methyldime | 1980 |
Tumorigenicity of 3'-hydroxymethyl, 3'-formyl, and 3'-carboxy derivatives of 4-(dimethylamino)azobenzene in rat liver.
Topics: Animals; Body Weight; Carcinogens; Diet; Liver; Liver Neoplasms, Experimental; Male; Methyldimethyla | 1981 |
3-Methylcholanthrene-inhibition of hepatocarcinogenesis in the rat due to 3'-methyl-4-dimethylaminoazobenzene or 2-acetylamino-fluorene: a comparative study.
Topics: 2-Acetylaminofluorene; Animals; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methylcholanth | 1982 |
[Distribution of 67Ga-citrate in 3'-methyl-4-dimethylaminoazobenzene-induced hepatoma of rats].
Topics: Animals; Autoradiography; Gallium Radioisotopes; Liver Neoplasms; Liver Neoplasms, Experimental; Mal | 1982 |
The alteration of gene expression in rat liver during chemical carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Gene Expression Regulation; Liver Neoplasms, | 1983 |
Inhibitory effects of autologous hepatic tumor suspension on the development of liver cell carcinoma in rats.
Topics: Animals; Antigens, Neoplasm; Liver Cirrhosis; Liver Neoplasms, Experimental; Male; Methyldimethylami | 1983 |
Acute effects of selected hepatotoxic agents on polyribosomes and protein synthesis in the livers of rats fed purified diets containing hepatocarcinogens.
Topics: 2-Acetylaminofluorene; Acute Disease; Animals; Carbon Tetrachloride; Carcinogens; Chemical and Drug | 1982 |
Histochemical and cytochemical study of butyrylcholinesterase activity in rat hepatocellular carcinomas induced by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Butyrylcholinesterase; Cholinesterases; Histocytochemistry; Liver Neoplasms, Experimental; | 1982 |
Hepatocytes with extraperoxisomal catalase in rats fed 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Catalase; Clofibrate; Enzyme Activation; Histocytochemistry; Liver Neoplasms, Experimental; | 1982 |
Alterations of cytoplasmic proteins in rat hepatomas during the administration of chemical carcinogen.
Topics: Animals; Carcinogens; Cytoplasm; Electrophoresis; Liver Neoplasms, Experimental; Male; Methyldimethy | 1980 |
Polysomal poly(A)+ RNA in liver of rats fed 3'-methyl-4-dimethylaminoazobenzene and in hepatoma induced by the same carcinogen.
Topics: Animals; DNA; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Nucleic Aci | 1980 |
Demonstration of embryonic-type hemoglobin in extramedullary hematopoietic cells in the liver during experimental liver carcinogenesis by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Bone Marrow; Hematopoietic Stem Cells; Hemoglobin E; Hemoglobins, Abnormal; Liver; Liver Ne | 1980 |
[Glycylproline dipeptidyl aminopeptidase activities in serum and liver of rats during 3'-methyl DAB administration (author's transl)].
Topics: Aminopeptidases; Animals; Dipeptides; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylamin | 1980 |
Comparative study of the phospholipid composition of plasma membranes isolated from rat primary hepatomas induced by 3'-methyl-4-dimethylaminoazobenzene and from normal growing rat livers.
Topics: Animals; Animals, Newborn; Cell Membrane; Liver; Liver Neoplasms, Experimental; Liver Regeneration; | 1980 |
Carcinogen daily dose-dependence of the biological features and development rate of hepatocellular carcinomas induced by 3'-methyl-4-dimethylaminoazobenzene in the rat.
Topics: alpha-Fetoproteins; Animals; Cell Differentiation; Liver Neoplasms; Liver Neoplasms, Experimental; M | 1994 |
Elevation of aldose reductase gene expression in rat primary hepatoma and hepatoma cell lines: implication in detoxification of cytotoxic aldehydes.
Topics: Aldehyde Reductase; Aldehydes; Animals; Antibody Specificity; Blotting, Northern; Carcinogens; Cell | 1995 |
Correlation between serum prolactin levels and hepatocellular tumorigenesis induced by 3'-methyl-4-dimethylaminoazobenzene in mice.
Topics: Adenoma; Animals; Bromocriptine; Estrogens; Female; Liver Neoplasms, Experimental; Methyldimethylami | 1995 |
Inhibition of 3'-methyl-4-dimethylaminoazobenzene-induced hepatocarcinogenesis in rat by dietary beta-carotene: changes in hepatic anti-oxidant defense enzyme levels.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; beta Carotene; Carotenoids; Diet; gamma-Glutamyltran | 1995 |
Immunocytochemical investigation of rat gamma-glutamyl transpeptidase in chemically-induced hepatocarcinogenesis using monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Bile Canaliculi; Cell Membrane; Epithelium; gamma-Glutamyltransfera | 1994 |
Effect of voluntary exercise on 3'-methyl-4-dimethylaminoazobenzene-induced hepatomas in male Jc1:Wistar rats.
Topics: Alkaline Phosphatase; Animals; Eating; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experiment | 1993 |
Gomisin A, a lignan component of Schizandora fruits, inhibits development of preneoplastic lesions in rat liver by 3'-methyl-4-dimethylamino-azobenzene.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Cell Nucleus; Cyclooctanes; Dioxoles; Drugs, Chinese | 1994 |
Sex differences at the initiation stage of rat liver carcinogenesis--influence of growth hormone.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme | 1993 |
Expression of non-hepatic-type S-adenosylmethionine synthetase isozyme in rat hepatomas induced by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Isoenzymes; Liver Neoplasms, Experimental; Male; Me | 1993 |
Modifying effects of chemicals on the development of liver preneoplastic placental glutathione S-transferase positive foci in analbuminemic and Sprague-Dawley rats.
Topics: Acetylglucosaminidase; Animals; Butylated Hydroxyanisole; Carcinogens; Clofibrate; Diethylnitrosamin | 1993 |
Suppression by oestrogen of hepatocellular tumourigenesis induced in mice by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Crosses, Genetic; Drug Implants; Estradiol; Female; Gluco | 1993 |
Effects of gomisin A on the promotor action and serum bile acid concentration in hepatocarcinogenesis induced by 3'-methyl-4-dimethylamino-azobenzene.
Topics: Animals; Anticarcinogenic Agents; Bile Acids and Salts; Body Weight; Carcinogens; Cyclooctanes; Deox | 1995 |
Different patterns of expression of ornithine decarboxylase mRNAs in rat liver after acute administration of hepatocarcinogens.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Division; Enzyme Induction; Gene Expression; Kinet | 1996 |
Inhibition of hepatocellular carcinoma development and erythrocyte polyamine levels in ODS rats fed on 3'-methyl-4-dimethylaminoazobenzene by hemicalcium ascorbate, 2-O-octadecylascorbic acid, and ascorbyl palmitate.
Topics: Animals; Antimutagenic Agents; Ascorbic Acid; Body Weight; Carcinogens; Erythrocytes; Free Radical S | 1996 |
Changes of expressions of phosphotyrosine phosphatases in rat hepatocellular carcinoma induced by 3'-methyl-4-dimethylamino-azobenzene.
Topics: Animals; Carcinogens; Cell Membrane; Cytosol; Gene Expression; Liver; Liver Neoplasms, Experimental; | 1996 |
Studies on the microsomal cytochrome P450s in the livers of carcinogen-resistant and sensitive rats during long-term administration of 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 | 1997 |
High expression of alpha-1-6 fucosyltransferase during rat hepatocarcinogenesis.
Topics: Aging; Animals; Carbohydrate Sequence; Carcinogens; Fucosyltransferases; Gene Expression; Liver; Liv | 1998 |
Hepatocyte growth factor stimulates DNA synthesis in rat preneoplastic hepatocytes but not in liver carcinoma cells.
Topics: Animals; Bromodeoxyuridine; DNA; Hepatocyte Growth Factor; Humans; Immunohistochemistry; Liver Neopl | 1998 |
Different responses other than the formation of DNA-adducts between the livers of carcinogen-resistant rats (DRH) and carcinogen-sensitive rats (Donryu) to 3'-methyl-4-dimethylaminoazobenzene administration.
Topics: Animals; Carcinogens; DNA Adducts; DNA Damage; Drug Resistance; Gene Expression; Gene Expression Reg | 1998 |
Genetic properties for the suppression of development of putative preneoplastic glutathione S-transferase placental form-positive foci in the liver of carcinogen-resistant DRH strain rats.
Topics: Animals; Blotting, Northern; Body Weight; Cell Division; Crosses, Genetic; Diethylnitrosamine; DNA; | 1999 |
Reduced T cell response in carcinogen-sensitive Donryu rats compared with carcinogen-resistant DRH rats.
Topics: Animals; Antibody Formation; Antigen-Presenting Cells; Antigens, Differentiation, T-Lymphocyte; Carc | 1999 |
Blunt cell growth potential in carcinogen resistant inbred DRH rats.
Topics: Animals; Carcinogens; Cell Division; Cells, Cultured; Drug Resistance; Fibroblasts; Inbreeding; Live | 2000 |
Investigation of possible involvement of several genes related to development of hepatocarcinogenesis in rats.
Topics: alpha-Fetoproteins; Animals; Base Sequence; Enhancer Elements, Genetic; Gene Expression Regulation, | 2000 |
Analyses of oxidative DNA damage and its repair activity in the livers of 3'-methyl-4-dimethylaminoazobenzene-treated rodents.
Topics: Animals; Carcinogens; Coloring Agents; Disease Susceptibility; DNA; DNA Damage; DNA Repair; DNA-Form | 2000 |
[The characteristics and significance of oncogenes expression in oval cells cultivated in vitro].
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression; Genes, myc; Genes, ras; | 1998 |
Resistance of DRH strain rats to chemical carcinogenesis of liver: genetic analysis of later progression stage.
Topics: Animals; Carcinoma, Hepatocellular; Chromosome Mapping; Crosses, Genetic; Disease Progression; Femal | 2002 |
[Liver reactivity to glucocorticoids in the process of chemical hepatic carcinogenesis].
Topics: Animals; Dexamethasone; DNA, Neoplasm; Enzyme Induction; Glucocorticoids; Hepatectomy; Indoleamine-P | 1979 |
Alpha-foetoprotein during chemically induced hepatocellular carcinoma in rats.
Topics: Aflatoxins; alpha-Fetoproteins; Animals; Bile; Liver Neoplasms; Liver Neoplasms, Experimental; Male; | 1978 |
Promotion by dietary phenobarbital of hepatocarcinogenesis by 2-methyl-N,N-dimethyl-4-aminoazobenzene in the rat.
Topics: Animals; Drug Synergism; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dimet | 1979 |
Enhancing effect of phenobarbital on the development of enzyme-altered islands and hepatocellular carcinomas initiated by 3'-methyl-4-(dimethylamino) azobenzene or diethylnitrosamine.
Topics: Adenosine Triphosphatases; Animals; Diethylnitrosamine; Drug Synergism; Liver; Liver Neoplasms, Expe | 1978 |
Effect of hepatocarcinogens on the adenine purine nucleotide cycle during the initiation phase of carcinogenesis.
Topics: 2-Acetylaminofluorene; Adenylosuccinate Lyase; Adenylosuccinate Synthase; AMP Deaminase; Animals; Ca | 1979 |
Biphasic change of proton magnetic relaxation times during azo-dye hepatocarcinogenesis.
Topics: Animals; Body Water; Hyperplasia; Liver Neoplasms, Experimental; Magnetic Resonance Spectroscopy; Ma | 1978 |
Elevation of the salvage synthesis of ribonucleic acid in the rat liver during the induction of hepatoma with 3'-methyl-4-(dimethylamino)azobenzene.
Topics: Animals; Cells, Cultured; Culture Techniques; Liver; Liver Neoplasms, Experimental; Male; Methyldime | 1978 |
Changes in polyamine content during hepatocarcinogenesis.
Topics: Animals; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; Polyamines; Rats | 1978 |
Expressions of c-fos and c-myc genes during 3'-methyl-4-dimethylaminoazobenzene (3'-MeDAB)-induced rat hepatocarcinoma.
Topics: Animals; Blotting, Southern; DNA; Female; Gene Expression; Genes, fos; Genes, myc; Liver Neoplasms, | 1992 |
Immunohistochemical study on epidermal growth factor (EGF) receptor during carcinogenesis in the rat liver.
Topics: Adenoma, Bile Duct; Animals; ErbB Receptors; Immunohistochemistry; Liver; Liver Neoplasms, Experimen | 1992 |
[Pathologic-ultrasonographic comparative study of carcinomatous lesions of experimental hepatic carcinoma in rats].
Topics: Animals; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Rats; Rats, Wist | 1992 |
Promoting effect of ovariectomy on hepatocellular tumorigenesis induced in mice by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Aging; Animals; Animals, Newborn; Female; Incidence; Liver Neoplasms, Experimental; Methyldimethylam | 1992 |
Anticarcinogenic effects of some Indian plant products.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Body Weight; Carcinoma, Squamous C | 1992 |
[Dynamic changes of fibronectin, DNA and morphology of the nuclei of experimental hepatoma in rats].
Topics: Animals; DNA, Neoplasm; Fibronectins; Image Processing, Computer-Assisted; Immunohistochemistry; Liv | 1992 |
[Evaluation of US contrast medium (LEVOVIST) to experimental liver cancer].
Topics: Animals; Contrast Media; Drug Evaluation; Image Enhancement; Liver Neoplasms, Experimental; Methyldi | 1992 |
Thymidine kinase and alpha-fetoprotein as biochemical markers of hepatocarcinogenesis induced by 3'-methyl-4-dimethylaminoazobenzene treatment in rats.
Topics: alpha-Fetoproteins; Animals; Biomarkers, Tumor; Isoenzymes; Kinetics; Liver; Liver Neoplasms, Experi | 1990 |
The appearance of hepatoma-associated chromosomal non-histone proteins in rat liver after a single dose of 3'-MDAB followed by treatment of phenobarbital.
Topics: alpha-Fetoproteins; Animals; Biomarkers, Tumor; Cell Nucleus; Chromatin; Chromosomal Proteins, Non-H | 1990 |
Suppression of messenger ribonucleic acid for glutathione peroxidase in chemically induced rat hepatocellular carcinoma and its biological significance.
Topics: Animals; Blotting, Northern; Glutathione Peroxidase; Immunohistochemistry; Liver Neoplasms, Experime | 1990 |
The facilitated effect of retinol on rat hepatocarcinogenesis induced by 3'-methyl-4-dimethylaminoazobenzene.
Topics: alpha-Fetoproteins; Animals; Body Weight; Carrier Proteins; gamma-Glutamyltransferase; Liver Neoplas | 1991 |
[Inhibitory effect of UFT on rat hepatocarcinogenesis induced by 3'-methyl-4-dimethylaminoazobenzene and phenobarbital promotion].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Liver Neoplasms, Experimental; Male; Methyl | 1991 |
Protein binding, nuclear translocation and biliary secretion of metabolites of 3'-methyl-N,N-dimethyl-4-aminoazobenzene during hepatocarcinogenesis in rats.
Topics: 2-Acetylaminofluorene; Animals; Bile; Body Weight; Carcinogens; Cell Nucleus; Chromatography, Gel; C | 1991 |
The in vitro and in vivo cytotoxicity of menadione (vitamin K3) against rat transplantable hepatoma induced by 3'-methyl-4-dimethyl-aminoazobenzene.
Topics: Animals; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Neoplasm Transplantatio | 1991 |
Effects of gomisin A on hepatocarcinogenesis by 3'-methyl-4-dimethylaminoazobenzene in rats.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Cyclooctanes; Dioxoles; Lignans; Liver Neoplasms, Exp | 1991 |
Roles of ovaries and testes in hepatocellular tumorigenesis induced in mice by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Adenoma; Animals; Clone Cells; Female; Isoenzymes; Liver Neoplasms; Liver Neoplasms, Experimental; M | 1991 |
Appearance of a carcinoid-like pattern in rat hepatic tumors induced by 3'-methyl-4-dimethyl-aminoazobenzene.
Topics: Animals; Carcinoid Tumor; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; p-Dime | 1991 |
Different effects of carbon tetrachloride on carcinogen-induced hepatocellular carcinoma and normal liver of the rat: lowered lipid peroxidation and accelerated necrosis in cancer.
Topics: Animals; Ascorbic Acid; Azo Compounds; Carbon Tetrachloride; Fatty Acids; Fatty Liver; Lipid Peroxid | 1991 |
Retinyl acetate inhibition of 3'-methyl-4-dimethyl-aminoazobenzene induced hepatic neoplasia.
Topics: Adenylosuccinate Lyase; Animals; Diterpenes; Female; gamma-Glutamyltransferase; Liver; Liver Neoplas | 1990 |
[Thymidine kinase activities in sera and liver tissues during hepatocarcinogenesis in rats treated with 3'-methyl-4-dimethylaminoazobenzene (3'-MeDAB)].
Topics: Animals; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Rats; Thymidine | 1990 |
A study on the regulation of translocation of glucose transporters during hepatocarcinogenesis induced by 3'-Me DAB.
Topics: Animals; Blotting, Western; Cell Membrane; Cytochalasin B; Glucose; Liver Neoplasms, Experimental; M | 1990 |
Bile canalicular alterations in hepatocyte nodules induced by 3'-methyl-4-dimethylaminoazobenzene in the rat: morphological clues on their pathogenesis and relevance to the neoplastic process.
Topics: Animals; Bile Canaliculi; Bile Ducts, Intrahepatic; Liver; Liver Neoplasms, Experimental; Male; Meth | 1990 |
[Effects of intra-arterial infusion of degradable starch microspheres on liver tissue blood flow].
Topics: Animals; Infusions, Intra-Arterial; Liver Circulation; Liver Neoplasms, Experimental; Male; Methyldi | 1990 |
Cell specificity of rat cytokeratin p39 during azo dye-induced hepatocarcinogenesis.
Topics: Animals; Azo Compounds; Histocytochemistry; Immunoenzyme Techniques; Keratins; Liver; Liver Neoplasm | 1985 |
Modifications of the expression of liver-specific and non-specific messenger RNAs during azo-dye hepatocarcinogenesis.
Topics: alpha-Fetoproteins; Animals; Fructose-Bisphosphate Aldolase; Gene Expression Regulation; Liver; Live | 1985 |
The prevention of chemical hepatocarcinogenesis in rats by combining active and passive immunization with alpha-fetoprotein.
Topics: Adenoma, Bile Duct; alpha-Fetoproteins; Animals; Antibodies; Antibody Formation; Antibody Specificit | 1985 |
Effect of timing of partial hepatectomy on the induction of preneoplastic liver foci in rats given hepatocarcinogens.
Topics: 2-Acetylaminofluorene; Animals; gamma-Glutamyltransferase; Hepatectomy; Hexachlorocyclohexane; Liver | 1986 |
Biological significance of AFP-positive cells in rat livers with hyperplastic nodules induced by 3'-Me-DAB; combined immunocytochemical and radioautographical studies.
Topics: alpha-Fetoproteins; Animals; Autoradiography; Histocytochemistry; Hyperplasia; Liver; Liver Neoplasm | 1987 |
Detection of the changes in serum proteins during chemical hepatocarcinogenesis by two-dimensional electrophoresis under non-denaturing conditions.
Topics: alpha-Fetoproteins; Animals; Blood Proteins; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Conce | 1987 |
[The effect of a mixture of tegafur with uracil (UFT) on hepatocarcinogenesis in rats induced by 3'-methyl-4-dimethylaminoazobenzene. I. The influence on production of alpha-fetoprotein].
Topics: alpha-Fetoproteins; Animals; Antineoplastic Combined Chemotherapy Protocols; Liver Neoplasms, Experi | 1988 |
Difference in gene expression between azo-dye-induced primary hepatomas and corresponding transplantable ascites hepatoma lines in rats.
Topics: Albumins; alpha-Fetoproteins; Alpha-Globulins; Animals; Apolipoprotein A-I; Apolipoproteins A; Ascit | 1988 |
[The pathological bases for the increase of serum alpha-fetoprotein level during hepatocarcinogenesis in rats].
Topics: alpha-Fetoproteins; Animals; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Methy | 1987 |
Demonstration by light and ultrastructural immunoperoxidase study of alpha-fetoprotein-positive non-hepatoma cells and hepatoma cells during 3'-methyl-4-dimethylaminoazobenzene hepatocarcinogenesis.
Topics: alpha-Fetoproteins; Animals; Carcinogens; Immunoenzyme Techniques; Immunohistochemistry; Liver Neopl | 1988 |
Cellular expression of alpha-fetoprotein gene and its relation to albumin gene expression during rat azo-dye hepatocarcinogenesis.
Topics: Albumins; alpha-Fetoproteins; Animals; Cell Division; Liver; Liver Neoplasms, Experimental; Male; Me | 1989 |
Change in the ploidy state of rat liver cells during chemical hepatocarcinogenesis and its relationship to the increased expression of alpha-fetoprotein.
Topics: alpha-Fetoproteins; Animals; Flow Cytometry; Gene Expression; Immunoenzyme Techniques; Liver; Liver | 1989 |
Synergistic effects of low-dose hepatocarcinogens in induction of glutathione S-transferase P-positive foci in the rat liver.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Carbazoles; Carcinogens; Diethylnitrosamine; Drug Sy | 1989 |
Effect of ethanol on hepatocarcinogenesis initiated in rats with 3'-methyl-4-dimethylaminoazobenzene in the absence of liver injuries.
Topics: Animals; Cholesterol; Drug Synergism; Ethanol; Liver; Liver Neoplasms, Experimental; Male; Methyldim | 1989 |
Inhibitory effect of fumaric acid on 3'-methyl-4-(dimethylamino)azobenzene-induced hepatocarcinogenesis in rats.
Topics: Animals; Antineoplastic Agents; Fumarates; Liver Neoplasms, Experimental; Male; Methyldimethylaminoa | 1989 |
The biphasic change of cytosolic acetyl-CoA hydrolase in rat liver during 3'-methyl-4-dimethylaminoazobenzene hepatocarcinogenesis.
Topics: Acetyl-CoA Hydrolase; Animals; Cytosol; Enzyme-Linked Immunosorbent Assay; Immunodiffusion; Liver; L | 1989 |
Calciferin and cathepsin D-like acid protease in serum in acute and chronic liver injuries in rats and humans.
Topics: Acute Disease; Animals; Cathepsin D; Chronic Disease; Female; Hepatectomy; Humans; Liver; Liver Dise | 1989 |
Promoting effects of phenobarbital and 3'-methyl-4-dimethylaminoazobenzene on the appearance of gamma-glutamyltranspeptidase positive foci in rat liver pretreated with varying doses of diethylnitrosamine.
Topics: Animals; Cocarcinogenesis; Diethylnitrosamine; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Ex | 1985 |
Decreased induction of gamma-glutamyltransferase activity by 3'-methyl-4-dimethylaminoazobenzene in the liver of rats given carcinogen-containing diet for several generations.
Topics: Animals; Animals, Newborn; Drug Resistance; Enzyme Induction; Female; gamma-Glutamyltransferase; Glu | 1986 |
Promotion of 3'-methyl-4-dimethylaminoazobenzene-initiated adult rat liver cells to malignant state by phenobarbital in culture.
Topics: Animals; Cell Cycle; Cell Transformation, Neoplastic; Epithelium; gamma-Glutamyltransferase; Liver; | 1986 |
Pleiotropic drug resistance in hepatocytes induced by carcinogens administered to rats.
Topics: 2-Acetylaminofluorene; Adaptation, Physiological; Animals; Carcinogens; Drug Resistance; gamma-Gluta | 1987 |
In vivo and in vitro test for growth potential of liver cells from rats during early stage of hepatocarcinogenesis by 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Cell Division; In Vitro Techniques; Liver; Liver Neoplasms, Experimental; Male; Methyldimet | 1989 |
High expression of an N-acetylglucosaminyltransferase III in 3'-methyl DAB-induced hepatoma and ascites hepatoma.
Topics: Aging; Animals; Animals, Newborn; Carbohydrate Conformation; Carbohydrate Sequence; Female; Fetus; G | 1988 |
Azo dye-induced alterations in vitamin B-6 metabolism and in pyridoxal 5'-phosphate-binding proteins in rat liver.
Topics: Animals; Cytosol; Densitometry; Enzyme-Linked Immunosorbent Assay; Liver; Liver Neoplasms, Experimen | 1986 |
Effect of intrahepatic arterial infusion of 131I-labelled lipiodol on hepatocellular carcinoma of rat.
Topics: Animals; Injections, Intra-Arterial; Iodine Radioisotopes; Iodized Oil; Liver; Liver Neoplasms, Expe | 1986 |
Presence of albumin-positive cells in the liver of analbuminemic rats and their increase on treatment with hepatocarcinogens.
Topics: 2-Acetylaminofluorene; Age Factors; Animals; Diethylnitrosamine; Hepatectomy; Liver; Liver Neoplasms | 1986 |
Detection of mRNAs present at low concentrations in rat liver by in situ hybridization: application to the study of metabolic regulation and azo dye hepatocarcinogenesis.
Topics: Animals; DNA; DNA, Recombinant; Fructose-Bisphosphate Aldolase; Liver; Liver Neoplasms, Experimental | 1987 |
Hepatocarcinogenic activities of hydroxymethyl derivatives of 4-(N,N-dimethylamino)azobenzene in ACI/N rats.
Topics: Animals; Biotransformation; Carcinogens; Hydroxylation; Liver Neoplasms, Experimental; Methyldimethy | 1987 |
A study of the regulation of the glucose transporter in the plasma membranes of hepatoma cells induced by 3'-Me DAB.
Topics: Animals; Cell Membrane; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Microsom | 1987 |
Quantitative electron microscopy of carcinogen-induced alterations in hepatocyte rough endoplasmic reticulum. I. Chronic effect of 3'MeDAB and short-term effects of azo dyes of different carcinogenic potentials.
Topics: Animals; Endoplasmic Reticulum; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobe | 1988 |
Dose-dependent induction of liver and thyroid neoplastic lesions by short-term administration of 2-amino-3-methylimidazo[4,5-f]quinoline combined with partial hepatectomy followed by phenobarbital or low dose 3'-methyl-4-dimethylaminoazobenzene promotion.
Topics: 2-Acetylaminofluorene; Animals; Cocarcinogenesis; Dose-Response Relationship, Drug; Hepatectomy; Liv | 1988 |
Comparative study of the levels of sialyltransferases responsible for the formation of sugar chains in glycoproteins and gangliosides in rat liver and hepatomas.
Topics: Animals; Gangliosides; Glycolipids; Glycoproteins; Liver; Liver Neoplasms, Experimental; Lung Neopla | 1988 |
Age related variations of hepatocarcinogenic effect of azo dye (3'-MDAB) as linked to the level of hepatocyte polyploidization.
Topics: Aging; Animals; Histones; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; | 1988 |
Reactivation of rat insulin-like growth factor II gene during hepatocarcinogenesis.
Topics: Animals; Blotting, Northern; Cell Transformation, Neoplastic; Female; Gene Expression Regulation; Ge | 1988 |
Analysis of hepatocyte plasma membrane polarity during rat azo dye hepatocarcinogenesis using monoclonal antibodies directed against domain-associated antigens.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens, Neoplasm; Antigens, Surface; Cell D | 1988 |
[Pathological study of hepatocarcinogenesis in rats induced by 3'-Me-DAB].
Topics: Animals; Cell Transformation, Neoplastic; Liver Neoplasms, Experimental; Male; Methyldimethylaminoaz | 1988 |
Inhibitory effects of synthetic acidic retinoid and polyprenoic acid on the development of hepatoma in rats induced by 3'-methyl-N, N-dimethyl-4-aminoazobenzene.
Topics: Animals; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Pyridines; Rats; Rats, | 1988 |
Specific lectin bindings to oval cells and proliferated bile ductules.
Topics: 1-Naphthylisothiocyanate; 2-Acetylaminofluorene; Animals; Bile Ducts; Binding Sites; Epithelial Cell | 1988 |
Characterization of tumor specific antigens on the plasma membrane surface of rat hepatomas induced by 3'-Me DAB and identification of the common tumor specific antigens from rat hepatomas induced by different chemical hepatocarcinogens.
Topics: 2-Acetylaminofluorene; Animals; Antigens, Neoplasm; Antigens, Surface; Diethylnitrosamine; Liver Neo | 1988 |
Tyrosine protein kinase in preneoplastic and neoplastic rat liver.
Topics: Affinity Labels; Animals; Antibodies; Diethylnitrosamine; Liver Neoplasms, Experimental; Male; Methy | 1988 |
Persistently decreased hepatic levels of 5'-deoxy-5'-methylthioadenosine during regeneration of and chemical carcinogenesis in rat liver.
Topics: Animals; Hepatectomy; Inosine; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Methy | 1986 |
Inhibitory effect of fumaric acid on hepatocarcinogenesis by thioacetamide in rats.
Topics: Acetamides; Animals; Fumarates; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobe | 1987 |
Inhibition of neoplastic development in rat liver, kidney, oesophagus and forestomach by 4,4'-diaminodiphenylmethane administration.
Topics: 2-Acetylaminofluorene; Aniline Compounds; Animals; Esophageal Neoplasms; Kidney Neoplasms; Liver Neo | 1987 |
Time course of dolichol and dolichyl phosphate during chemical carcinogenesis in rat liver.
Topics: Acyl Coenzyme A; Animals; Diethylnitrosamine; Diterpenes; Dolichol Phosphates; Dolichols; Hepatectom | 1987 |
Promoting and anticarcinogenic effects of phenobarbital and DDT in the rat hepatocarcinogenesis.
Topics: Animals; Cocarcinogenesis; DDT; Drug Interactions; Liver Neoplasms, Experimental; Male; Methyldimeth | 1986 |
Elevated expression and cell cycle deregulation of a mitosis-associated target polypeptide of a carcinogen in hyperplastic and malignant rat hepatocytes.
Topics: 2-Acetylaminofluorene; Adenoma; Animals; Cell Cycle; Hyperplasia; Liver; Liver Neoplasms, Experiment | 1987 |
Surface properties of cell membrane in early stage of transformed cell. I. Early detection of transformed cell by concanavalin A. II. Properties of plasma membrane of transformed rat liver cell induced by 3'-Me DAB.
Topics: Animals; Cell Membrane; Cell Transformation, Neoplastic; Concanavalin A; Liver Neoplasms, Experiment | 1985 |
Enhancement of hepatocarcinogenesis by sorbitan fatty acid ester, a liver pyruvate kinase activity-reducing substance.
Topics: Animals; Bile Ducts; Body Weight; Hemangioma; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; | 1985 |
A search for nuclear RNA lost in azo dye-induced transplantable hepatoma.
Topics: Animals; Cell Nucleus; Liver; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; Nucleic | 1985 |
Comparison of drug-metabolizing activities in the livers of carcinogen-sensitive parent rats and carcinogen-resistant descendants.
Topics: Animals; Benzopyrene Hydroxylase; Biotransformation; Cytochrome P-450 Enzyme System; Drug Resistance | 1985 |
Changes in polypeptide pattern of rat liver cells during chemical hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Aging; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Liver; L | 1985 |
Oncogene expression in rat hepatomas and during hepatocarcinogenesis.
Topics: Animals; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Oncogenes; Rats; Rats, | 1985 |
Studies in vivo to investigate the status of 4-N-pyrrolidinylazobenzene as a pure cancer initiating agent to the rat liver.
Topics: Animals; Azo Compounds; Carcinogens; DNA Repair; Liver; Liver Neoplasms, Experimental; Male; Methyld | 1985 |
Effects of selenium supplementation on hepatocarcinogenesis in rats.
Topics: Animals; Body Weight; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Org | 1985 |