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methyldimethylaminoazobenzene and Cocarcinogenesis

methyldimethylaminoazobenzene has been researched along with Cocarcinogenesis in 7 studies

Methyldimethylaminoazobenzene: A very potent liver carcinogen.
3-methyl-4'-dimethylaminoazobenzene : A member of the class of azobenzenes that is azobenzene in which one of the phenyl groups is substituted at position 3 by a methyl group, while the other is substituted at position 4 by a dimethylamino group. It is a potent liver carcinogen.

Cocarcinogenesis: The combination of two or more different factors in the production of cancer.

Research Excerpts

ExcerptRelevanceReference
"025% 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) for two weeks combined with partial hepatectomy at the end of the first week and followed by long-term treatment with phenobarbital (PB) or 3'-methyl-4-dimethylaminoazobenzene (3'-Me-DAB) from week 3 to week 86 resulted in dose-dependent development of liver and thyroid neoplastic and preneoplastic lesions."1.27Dose-dependent induction of liver and thyroid neoplastic lesions by short-term administration of 2-amino-3-methylimidazo[4,5-f]quinoline combined with partial hepatectomy followed by phenobarbital or low dose 3'-methyl-4-dimethylaminoazobenzene promotion. ( Asamoto, M; Inoue, T; Ito, N; Nagao, M; Ogiso, T; Tsuda, H, 1988)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mori, Y1
Niwa, T1
Toyoshi, K1
Pitot, HC1
Goldsworthy, T1
Moran, S1
Sirica, AE1
Weeks, J1
Yamamoto, R1
Tatsuta, M1
Yamamoto, T1
Terada, N1
Dong, JM1
Kilianska, Z1
Fukuda, K1
Chiu, JF1
Shirai, T1
Hosoda, K1
Hirose, K1
Hirose, M1
Ito, N2
Tsuda, H1
Asamoto, M1
Ogiso, T1
Inoue, T1
Nagao, M1
Kitagawa, T1

Reviews

1 review available for methyldimethylaminoazobenzene and Cocarcinogenesis

ArticleYear
Properties of incomplete carcinogens and promoters in hepatocarcinogenesis.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; Hepate

1982

Other Studies

6 other studies available for methyldimethylaminoazobenzene and Cocarcinogenesis

ArticleYear
Participation of cytochrome P450 in mutagenic activation of the carcinogen 3'-hydroxymethyl-N,N-dimethyl-4-aminoazobenzene and its N-demethylated compounds by rat liver.
    Mutation research, 1983, Volume: 122, Issue:1

    Topics: Animals; Biotransformation; Carcinogens; Cocarcinogenesis; Cytochrome P-450 Enzyme System; Liver; Me

1983
The later administration of progesterone more rapidly activates dormant mouse mammary tumor cells initiated by 3'-methyl-4-dimethylaminoazobenzene.
    Cancer letters, 1996, Feb-27, Volume: 100, Issue:1-2

    Topics: Aging; Animals; Carcinogens; Cocarcinogenesis; Drug Interactions; Estradiol; Female; Mammary Neoplas

1996
The appearance of hepatoma-associated chromosomal non-histone proteins in rat liver after a single dose of 3'-MDAB followed by treatment of phenobarbital.
    Cancer letters, 1990, Jun-15, Volume: 51, Issue:3

    Topics: alpha-Fetoproteins; Animals; Biomarkers, Tumor; Cell Nucleus; Chromatin; Chromosomal Proteins, Non-H

1990
Promoting effects of phenobarbital and 3'-methyl-4-dimethylaminoazobenzene on the appearance of gamma-glutamyltranspeptidase positive foci in rat liver pretreated with varying doses of diethylnitrosamine.
    Cancer letters, 1985, Sep-15, Volume: 28, Issue:2

    Topics: Animals; Cocarcinogenesis; Diethylnitrosamine; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Ex

1985
Dose-dependent induction of liver and thyroid neoplastic lesions by short-term administration of 2-amino-3-methylimidazo[4,5-f]quinoline combined with partial hepatectomy followed by phenobarbital or low dose 3'-methyl-4-dimethylaminoazobenzene promotion.
    Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:6

    Topics: 2-Acetylaminofluorene; Animals; Cocarcinogenesis; Dose-Response Relationship, Drug; Hepatectomy; Liv

1988
Promoting and anticarcinogenic effects of phenobarbital and DDT in the rat hepatocarcinogenesis.
    Toxicologic pathology, 1986, Volume: 14, Issue:3

    Topics: Animals; Cocarcinogenesis; DDT; Drug Interactions; Liver Neoplasms, Experimental; Male; Methyldimeth

1986