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methyldimethylaminoazobenzene and Abnormalities, Autosome

methyldimethylaminoazobenzene has been researched along with Abnormalities, Autosome in 7 studies

Methyldimethylaminoazobenzene: A very potent liver carcinogen.
3-methyl-4'-dimethylaminoazobenzene : A member of the class of azobenzenes that is azobenzene in which one of the phenyl groups is substituted at position 3 by a methyl group, while the other is substituted at position 4 by a dimethylamino group. It is a potent liver carcinogen.

Research Excerpts

ExcerptRelevanceReference
"However, mutations and chromosomal aberrations were significantly induced by N-acetoxy-4-methylaminoazobenzene, an active metabolite of 4-dimethylaminoazobenzene or 3'-Me-DAB in the presence of liver microsomes."1.26Effect of 3'-methyl-4-dimethylaminoazobenzene in the induction of malignant transformation and of 8-azaguanine-resistant mutations and chromosomal aberrations in a diploid clone derived from normal rat liver cells in culture. ( Sato, J; Tokiwa, T, 1982)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyazaki, M3
Wahid, S1
Matsuura, K1
Tsunashima, M1
Nakabayashi, H1
Miyano, K1
Sato, J6
Tokiwa, T3
Nishiyama, S1
Yoshimoto, J1
Lafond, MG1
Calabrese, EJ1
Handa, Y2
Hishinuma, T1
Degawa, M1
Hashimoto, Y1

Reviews

1 review available for methyldimethylaminoazobenzene and Abnormalities, Autosome

ArticleYear
Is the selenium drinking water standard justified?
    Medical hypotheses, 1979, Volume: 5, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adolescent; Animals; Antineoplastic Agents; Carcinogens; Chromosom

1979

Other Studies

6 other studies available for methyldimethylaminoazobenzene and Abnormalities, Autosome

ArticleYear
Effect of 3'-methyl-4-dimethylaminoazobenzene on liver cells from adult rat in primary culture.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1982, Volume: 181, Issue:1

    Topics: Animals; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome

1982
Cytological alteration of cultured rat liver cells by 3'-methyl-4-dimethylaminoazobenzene with special reference to chromosome changes, changes of growth patterns at a colony level and alpha-fetoprotein production.
    Acta medica Okayama, 1980, Volume: 34, Issue:3

    Topics: alpha-Fetoproteins; Animals; Cell Division; Cell Line; Chromosome Aberrations; Liver; Methyldimethyl

1980
Effect of 3'-methyl-4-dimethylaminoazobenzene in the induction of malignant transformation and of 8-azaguanine-resistant mutations and chromosomal aberrations in a diploid clone derived from normal rat liver cells in culture.
    In vitro, 1982, Volume: 18, Issue:6

    Topics: Animals; Azaguanine; Cell Transformation, Neoplastic; Chromosome Aberrations; Clone Cells; Drug Resi

1982
Transformation of primary cultured and co-cultured adult rat liver cells by 3'-methyl-4-dimethylaminoazobenzene.
    Acta medica Okayama, 1985, Volume: 39, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; DNA; Female; gamm

1985
Effect of phenobarbital on adult rat liver cells treated with 3'-methyl-4-dimethylaminoazobenzene in primary culture.
    Journal of cancer research and clinical oncology, 1985, Volume: 110, Issue:3

    Topics: Animals; Cells, Cultured; Chromosome Aberrations; Dimethyl Sulfoxide; Dose-Response Relationship, Dr

1985
Malignant transformation of rat liver cells by N-benzoyloxy-3'-methyl-4-methylaminoazobenzene and its related compound.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:1

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; DNA

1986
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