methylcellulose and Pancytopenia

methylcellulose has been researched along with Pancytopenia* in 1 studies

Other Studies

1 other study(ies) available for methylcellulose and Pancytopenia

Article	Year
Increased susceptibility to pneumococci after ligation of the splenic artery in experimental hypersplenism. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1983, Volume: 15, Issue:2 22 male Sprague-Dawley rats were divided into two groups, of which group I received methylcellulose and group II saline intraperitoneally for 12 weeks. After ligation of the splenic artery of the animals in group I and sham operation of the rats in group II, the injections were continued for a further 9 weeks. At the operation, the group I animals all showed signs of hypersplenism with anemia, and leuko- and thrombocytopenia. The platelet counts normalized after the operation, a marked leukocytosis developed and the anemia was further aggravated. At the end of the study, the animals were challenged with 4 x 10(6) colony-forming units of pneumococci type 1, resulting in deaths of 11 of 12 animals in group I, in contrast to survival of all 10 rats in group II (p = 0.000017). Topics: Animals; Hypersplenism; Leukocytosis; Ligation; Male; Methylcellulose; Pancytopenia; Pneumococcal Infections; Rats; Rats, Inbred Strains; Splenic Artery	1983

Article

Year

Increased susceptibility to pneumococci after ligation of the splenic artery in experimental hypersplenism.

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1983, Volume: 15, Issue:2

22 male Sprague-Dawley rats were divided into two groups, of which group I received methylcellulose and group II saline intraperitoneally for 12 weeks. After ligation of the splenic artery of the animals in group I and sham operation of the rats in group II, the injections were continued for a further 9 weeks. At the operation, the group I animals all showed signs of hypersplenism with anemia, and leuko- and thrombocytopenia. The platelet counts normalized after the operation, a marked leukocytosis developed and the anemia was further aggravated. At the end of the study, the animals were challenged with 4 x 10(6) colony-forming units of pneumococci type 1, resulting in deaths of 11 of 12 animals in group I, in contrast to survival of all 10 rats in group II (p = 0.000017).

Topics: Animals; Hypersplenism; Leukocytosis; Ligation; Male; Methylcellulose; Pancytopenia; Pneumococcal Infections; Rats; Rats, Inbred Strains; Splenic Artery

1983