methylcellulose and Myopia

We conducted a study to evaluate the shortterm effect on intraocular pressure (IOP) following extracapsular cataract extraction using either sodium hyaluronate 1% or hydroxypropyl methylcellulose 2%. In both groups a non-significant rise in IOP at day 1 was followed by a significant decline in IOP at day 3 to values below the pre-operative level (p < 0.05). At day 7 both groups had returned to pre-operative values. Post-operatively, spikes in intraocular pressure (> 25 mmHg) were seen equally in both groups. Patients with pre-operatively diagnosed open-angle glaucoma, high myopia and diabetic retinopathy are considered to be at high risk concerning post-operatively elevated IOP, but with small variation these patients followed the main trend.

Topics: Adult; Aged; Aged, 80 and over; Cataract Extraction; Diabetic Retinopathy; Female; Glaucoma, Open-Angle; Humans; Hyaluronic Acid; Hypromellose Derivatives; Intraocular Pressure; Lenses, Intraocular; Male; Methylcellulose; Middle Aged; Myopia; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Risk Factors

To analyze and compare the postoperative outcomes of eyes with accidental intraoperative inversion of implantable collamer lens (ICL) and viscocannula-assisted reinversion in high myopia.. Retrospective observational case comparison.. Institutional practice.. Consecutive eyes with accidental intraoperative inversion of ICL and viscocannula-assisted reinversion from January 2007 to September 2010 were analyzed retrospectively. They were compared with the fellow eyes with normal ICL implantation at 1 month, 6 months, and 2 years.. Uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), corneal pachymetry, endothelial cell loss, intraocular pressure, lens transparency, anterior chamber depth, and postoperative uveitis.. A total of 206 myopic eyes had ICL implantation. Eight eyes (3.8%) of 8 patients had accidental intraoperative reinversion. Their fellow eyes had normal ICL implantation. There was no significant change (P = .611) in UCVA (reinverted and fellow eyes) at 2 years. There was no significant difference in postoperative UCVA (P = .611) and BCVA (P = .854) between the reinverted and the fellow eyes. The mean endothelial loss at 1 month, 6 months, and 2 years was 0.96% ± 0.5%, 0.92% ± 0.63%, and 0.89% ± 0.52% respectively in the reinverted eyes. There was no significant difference in the endothelial loss between the 2 groups at 1 month (P = .753), 6 months (P = .834), and 2 years (P = .916). One out of 8 eyes with reinversion had postoperative corneal edema, which resolved at 48 hours. None of the eyes reported uveitis or glaucoma. There was no loss of lens transparency.. Intraoperative inversion can occur during insertion of ICL and viscocannula-assisted reinversion can be performed without significant complications.

Topics: Anterior Chamber; Cell Count; Corneal Endothelial Cell Loss; Corneal Topography; Endothelium, Corneal; Humans; Hypromellose Derivatives; Iatrogenic Disease; Intraocular Pressure; Intraoperative Complications; Lens Implantation, Intraocular; Medical Errors; Methylcellulose; Myopia; Phakic Intraocular Lenses; Refraction, Ocular; Reoperation; Retrospective Studies; Treatment Outcome; Viscoelastic Substances; Visual Acuity

Topics: Humans; Intraoperative Complications; Lens Implantation, Intraocular; Medical Errors; Methylcellulose; Myopia; Phakic Intraocular Lenses; Viscoelastic Substances

Ciliary muscle function in patients with Adie's syndrome was studied retrospectively in 122 patients and prospectively in 17 patients. When a careful history was taken, two thirds of the patients had ciliary muscle-related symptoms. Most of the patients with Adie's syndrome had a moderate accomodative paresis, but there was a strong tendency for the ciliary muscle to recover with time. Many patients showed a tonicity of accommodation, especially those who had had the condition for several years. Astigmatism could be induced with accommodation in one third of patients. This may be related to segmental paralysis of the ciliary muscle. Seventy-three percent of the patients showed supersensitivity of the ciliary muscle in the involved eye, when both eyes were treated with a mixture of 0.25% pilocarpine hydrochloride and hydroxypropyl methylcellulose (Isopto Carpine). This may be a clinical aid in diagnosing Adie's syndrome. Two patients were found to have bilateral ciliary muscle dysfunction but only unilateral pupillary abnormalities. These two patients may have had a "pupil-sparing" Adie's syndrome.

Topics: Accommodation, Ocular; Adie Syndrome; Adolescent; Adult; Astigmatism; Child; Ciliary Body; Female; Humans; Male; Methylcellulose; Myopia; Pilocarpine; Prospective Studies; Pupil; Retrospective Studies