methylcellulose and Mouth-Diseases

methylcellulose has been researched along with Mouth-Diseases* in 9 studies

Trials

2 trial(s) available for methylcellulose and Mouth-Diseases

Article	Year
Aqueous hydrocortisone mouthwash solution: clinical evaluation. Acta odontologica Scandinavica, 1998, Volume: 56, Issue:3 Patients often experience difficulties in applying topical steroids in orabase to the oral mucosa, particularly when large areas need to be covered. An aqueous hydrocortisone mouthwash solution has been developed, one that was anticipated to be more acceptable to patients. The solution contains hydrocortisone (0.3% w/v) in a 4.5% (w/v) 2-hydroxypropyl-beta-cyclodextrin solution. Hydroxypropylmethylcellulose (0.5% w/v) was used to increase the viscosity of the solution and to promote the hydrocortisonecyclodextrin complex. One hundred and two patients with aphthous ulceration, lichen planus, and other mucosal conditions used the mouthwash in an open clinical efficacy study. Most patients reported some or considerable improvement following a 2-week course of treatment with the mouthwash: 26 of 33 (78.8%) patients with aphthous ulceration were 'much better', as were 26 of 54 (48.1%) patients with lichen planus and 5 of 16 (31.3%) patients with other mucosal lesions. No serious side effects were reported. Aqueous mouthwash solutions offer a potential vehicle for topical steroid therapy of oral mucosal lesions. Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; beta-Cyclodextrins; Chelating Agents; Chemistry, Pharmaceutical; Child; Cyclodextrins; Excipients; Female; Humans; Hydrocortisone; Hypromellose Derivatives; Lichen Planus, Oral; Male; Methylcellulose; Middle Aged; Mouth Diseases; Mouth Mucosa; Mouthwashes; Pharmaceutic Aids; Pharmaceutical Vehicles; Remission Induction; Stomatitis, Aphthous; Treatment Outcome; Viscosity	1998
Treatment of oral ulcerations with Bacid (Lactobacillus acidophilus). Oral surgery, oral medicine, and oral pathology, 1970, Volume: 30, Issue:2 Topics: Analysis of Variance; Anti-Infective Agents, Local; Clinical Trials as Topic; Female; Herpes Simplex; Humans; Lactobacillus acidophilus; Male; Mental Disorders; Methylcellulose; Mouth Diseases; Mouthwashes; Stomatitis, Aphthous	1970

Article

Year

Aqueous hydrocortisone mouthwash solution: clinical evaluation.

Acta odontologica Scandinavica, 1998, Volume: 56, Issue:3

Patients often experience difficulties in applying topical steroids in orabase to the oral mucosa, particularly when large areas need to be covered. An aqueous hydrocortisone mouthwash solution has been developed, one that was anticipated to be more acceptable to patients. The solution contains hydrocortisone (0.3% w/v) in a 4.5% (w/v) 2-hydroxypropyl-beta-cyclodextrin solution. Hydroxypropylmethylcellulose (0.5% w/v) was used to increase the viscosity of the solution and to promote the hydrocortisonecyclodextrin complex. One hundred and two patients with aphthous ulceration, lichen planus, and other mucosal conditions used the mouthwash in an open clinical efficacy study. Most patients reported some or considerable improvement following a 2-week course of treatment with the mouthwash: 26 of 33 (78.8%) patients with aphthous ulceration were 'much better', as were 26 of 54 (48.1%) patients with lichen planus and 5 of 16 (31.3%) patients with other mucosal lesions. No serious side effects were reported. Aqueous mouthwash solutions offer a potential vehicle for topical steroid therapy of oral mucosal lesions.

Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; beta-Cyclodextrins; Chelating Agents; Chemistry, Pharmaceutical; Child; Cyclodextrins; Excipients; Female; Humans; Hydrocortisone; Hypromellose Derivatives; Lichen Planus, Oral; Male; Methylcellulose; Middle Aged; Mouth Diseases; Mouth Mucosa; Mouthwashes; Pharmaceutic Aids; Pharmaceutical Vehicles; Remission Induction; Stomatitis, Aphthous; Treatment Outcome; Viscosity

1998

Treatment of oral ulcerations with Bacid (Lactobacillus acidophilus).

Oral surgery, oral medicine, and oral pathology, 1970, Volume: 30, Issue:2

Topics: Analysis of Variance; Anti-Infective Agents, Local; Clinical Trials as Topic; Female; Herpes Simplex; Humans; Lactobacillus acidophilus; Male; Mental Disorders; Methylcellulose; Mouth Diseases; Mouthwashes; Stomatitis, Aphthous

1970

Other Studies

7 other study(ies) available for methylcellulose and Mouth-Diseases

Article	Year
Lozenges, mouthwashes and gargles. Drug and therapeutics bulletin, 1972, Apr-28, Volume: 10, Issue:9 Topics: Amphotericin B; Anesthetics, Local; Anti-Bacterial Agents; Anti-Infective Agents, Local; Humans; Hydrocortisone; Methylcellulose; Mouth Diseases; Mouthwashes; Pharyngeal Diseases; Tablets	1972
New long-lasting lozenge protectant vehicle for oral mucosal disease. New York state journal of medicine, 1969, Mar-01, Volume: 69, Issue:5 Topics: Delayed-Action Preparations; Humans; Methylcellulose; Mouth Diseases; Mouth Mucosa; Pharmaceutical Vehicles; Solubility	1969
Clinical investigation of the use of benzocaine in orabase. Journal - Connecticut State Dental Association, 1968, Volume: 42, Issue:3 Topics: Anesthesia, Dental; Benzocaine; Dentistry; Methylcellulose; Mouth Diseases; Occlusive Dressings; Ointments; Pain; Pectins; Polyethylenes; Tooth Extraction; Wound Healing	1968
Long-lasting lozenges: dissolution studies with CU 701-1 in patients with oral lesions and in volunteer (normal) subjects. Military medicine, 1968, Volume: 133, Issue:6 Topics: Adult; Delayed-Action Preparations; Glycols; Humans; Male; Methylcellulose; Mouth Diseases; Tablets; Time Factors	1968
Compatibility of a new adhesive vehicle (Orahesive) with other formulation bases. Annals of dentistry, 1967, Volume: 26, Issue:3 Topics: Drug Compounding; Drug Stability; Gelatin; Humans; Methylcellulose; Mineral Oil; Mouth Diseases; Occlusive Dressings; Pectins; Pharmaceutical Vehicles	1967
Preliminary clinical trials of a new oral adhesive bandage. Journal of biomedical materials research, 1967, Volume: 1, Issue:4 Topics: Bandages; Gelatin; Humans; Methylcellulose; Mouth Diseases; Mouth Mucosa; Occlusive Dressings; Polyethylenes; Tooth Extraction; Wound Healing	1967
The treatment of intraoral chemical burns. Journal of oral therapeutics and pharmacology, 1965, Volume: 2, Issue:2 Topics: Adolescent; Adult; Aged; Aspirin; Borates; Burns, Chemical; Child; Chlorpromazine; Humans; Mental Disorders; Methylcellulose; Middle Aged; Mouth Diseases; Promazine	1965