Page last updated: 2024-08-21

methylazoxymethanol acetate and Disease Models, Animal

methylazoxymethanol acetate has been researched along with Disease Models, Animal in 146 studies

Research

Studies (146)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (3.42)	18.7374
1990's	14 (9.59)	18.2507
2000's	33 (22.60)	29.6817
2010's	72 (49.32)	24.3611
2020's	22 (15.07)	2.80

Authors

Authors	Studies
Grace, AA; Sved, AF; Weeks, JJ	1
Cash, D; Davies, C; Gomes, FV; Grace, AA; Kiemes, A; Modinos, G; Simmons, C; Singh, N; Stone, JM; Turkheimer, F; Uliana, DL; Vernon, AC	1
An, Y; Lan, Y; Li, GY; Li, ML; Peng, Y	1
D'Addario, C; Di Bartolomeo, M; Di Martino, S; Di Marzo, V; Drago, F; Iannotti, FA; Micale, V; Piscitelli, F; Ruda-Kucerova, J; Stark, T; Wotjak, CT	1
Grace, AA; Zhu, X	2
Boley, AM; Eassa, NE; Elam, HB; Lodge, DJ; McCoy, AM; Perez, SM	1
Berta, B; Dusa, D; Gálosi, R; Kállai, V; Karádi, Z; Kertes, E; Kovács, A; László, K; Lénárd, L; Ollmann, T; Péczely, L; Tóth, A; Zagoracz, O	1
Chen, GY; Chen, L; Cheng, Y; Du, Y; Li, XS	1
Kopciuch, D; Kus, K; Murawiecka, P; Nowakowska, E; Paczkowska, A; Ratajczak, P; Słodzińska, I; Zaprutko, T	1
Gzielo, K; Holuj, M; Litwa, E; Nikiforuk, A; Popik, P; Potasiewicz, A; Socha, L	1
Babinska, Z; Bucolo, C; D'Addario, C; Di Bartolomeo, M; Di Marco, R; Di Marzo, V; Drago, F; Drazanova, E; Fedotova, J; Giurdanella, G; Iannotti, FA; Kratka, L; Mechoulam, R; Micale, V; Pekarik, V; Piscitelli, F; Platania, CBM; Ruda-Kucerova, J; Salomone, S; Starcuk, Z; Stark, T; Sulcova, A; Wotjak, CT	1
Boley, AM; Carless, MA; Donegan, JJ; Glenn, JP; Lodge, DJ	1
Babinska, Z; Hammer, T; Horska, K; Karpisek, M; Kotolova, H; Micale, V; Prochazka, J; Ruda-Kucerova, J; Stark, T	1
Bienertova-Vasku, J; Horska, K; Hruska, P; Kucera, J; Kuruczova, D; Micale, V; Ruda-Kucerova, J	1
Hu, LB; Huang, J; Ling, Y; Shen, HW; Xu, L; Zhang, XQ	1
Grace, AA; Sonnenschein, SF	2
Cabungcal, JH; Cuenod, M; Do, KQ; Grace, AA; Uliana, DL; Zhu, X	1
Kim, EJ; Kim, MJ; Lee, M; Yum, MS	1
Bilecki, W; Chmelova, M; Maćkowiak, M; Majcher-Maślanka, I; Wawrzczak-Bargieła, A	1
Babinska, Z; Micale, V; Ruda-Kucerova, J; Stark, T	1
Gálosi, R; Kállai, J; Kállai, V; Karádi, Z; László, K; Lénárd, L; Ollmann, T; Péczely, L; Petykó, Z; Szabó, I; Tóth, A	1
Elefant, F; Gao, WJ; Gulchina, Y; Snyder, MA; Xu, SJ	1
Alsiö, J; Bussey, TJ; Dourado, T; Gamallo-Lana, B; Lei, M; Mar, AC; Nilsson, SRO; Robbins, TW; Saksida, LM	1
Gomes, FV; Grace, AA; Zhu, X	1
Gill, KM; Grace, AA; Miller, SA	1
Bator, E; Latusz, J; Maćkowiak, M; Wędzony, K	1
Feng, GF; Hu, M; Li, CJ; Liu, JX; Liu, Y; Xu, JH; Yuan, B; Zhu, K	1
Bator, E; Głowacka, U; Latusz, J; Maćkowiak, M; Mudlaff, K; Radaszkiewicz, A	1
Azizi, M; Kashani, IR; Mokhtari, T; Nadji, SA; Omidi, N; Pasbakhsh, P; Pourabdollah, M; Sadr, M; Zendehdel, A	1
Grace, AA; Neves, GA	1
Edelson, JR; Gomes, FV; Grace, AA; Volk, DW	1
Gao, WJ; Han, G; Snyder, MA; Wang, MJ; Xing, B	1
Fenton, AA; Levy, ERJ; O'Reilly, KC; Patino, AV; Perica, MI	1
Huang, H; Huo, C; Liu, X; Ye, H; Zhao, J; Zhao, T	1
Gill, KM; Grace, AA; Sonnenschein, SF	1
Aivaliotis, M; Chalkiadaki, K; Chatzaki, E; Kyriazidis, E; Sidiropoulou, K; Stavroulaki, V; Velli, A; Vouvoutsis, V	1
Holuj, M; Nikiforuk, A; Piotrowska, D; Popik, P; Potasiewicz, A; Wojcik, M; Zajda, K	1
Babinska, Z; Bari, M; D'Addario, C; Di Bartolomeo, M; Di Marco, R; Di Marzo, V; Drago, F; Drazanova, E; Giurdanella, G; Iannotti, FA; Maccarrone, M; Mechoulam, R; Micale, V; Pekarik, V; Piscitelli, F; Ruda-Kucerova, J; Salomone, S; Starcuk, Z; Stark, T; Sulcova, A; Wotjak, CT	1
Donegan, JJ; Lodge, DJ; Perez, SM	1
Lin, JR; Nakagawasai, O; Nemoto, W; Odaira, T; Onogi, H; Sakuma, W; Srivastava, LK; Takahashi, K; Tan-No, K	1
Donny, EC; Grace, AA; Rupprecht, LE; Sved, AF; Weeks, JJ	1
Drago, F; Drazanova, E; Kratka, L; Kuchar, M; Maryska, M; Micale, V; Ruda-Kucerova, J; Starcuk, Z; Stark, T	1
Battaglia, GS; Cagnoli, C; Cipelletti, B; Colciaghi, F; de Curtis, M; Locatelli, D; Nobili, P; Zambon, S	1
Lodge, DJ	1
Abbah, J; Juliano, SL	1
Guo, N; Kimura, R; Osumi, N; Suto, F; Yanagawa, Y; Yoshizaki, K	1
Juliano, SL; Poluch, S	1
Lodge, DJ; Perez, SM	1
Abbah, J; Braga, MF; Juliano, SL	1
Cook, JM; Gill, KM; Grace, AA; Poe, MM	1
Chen, L; Lodge, DJ; Perez, SM	2
Gill, KM; Grace, AA	1
Carreno, FR; Frazer, A; Lodge, DJ; Perez, SM	1
Chen, SH; Gean, PW; Hsiao, YH; Hung, HC	1
Gomes, FV; Grace, AA; Guimarães, FS	1
Allen, P; Grace, AA; McGuire, P; Modinos, G	1
Jellett, AP; Jenks, K; Lucas, M; Scott, RC	1
Bannerman, DM; Gastambide, F; Janhunen, SK; Karjalainen, M; Palmer, C; Svard, H; Taylor, AM; Tricklebank, M	1
Goda, SA; Hunt, MJ; Kasicki, S; Olszewski, M; Piasecka, J; Rejniak, K; Whittington, MA	1
Bellinger, SA; Kleven, GA	1
Gálosi, R; Kállai, J; Kállai, V; Karádi, Z; Lénárd, L; Petykó, Z; Szabó, I; Tóth, A	1
Howe, WM; Kozak, R; Oomen, C; Tierney, PL; Young, DA	1
Aguilar, DD; Carless, MA; Giuffrida, A; Lodge, DJ; Neary, JL; Perez, SM	1
Bator, E; Latusz, J; Maćkowiak, M; Radaszkiewicz, A; Wędzony, K	1
Giermaziak, W; Kus, K; Murawiecka, P; Nowakowska, E; Ratajczak, P; Słodzińska, I	1
Grace, AA	1
Du, Y; Grace, AA	2
Amchova, P; Babinska, Z; Drago, F; Micale, V; Ruda-Kucerova, J; Stark, T; Sulcova, A	1
Gomes, FV; Grace, AA; Rincón-Cortés, M	1
Coman, D; de Graaf, RA; Groman, SM; Herman, P; Hyder, F; Jiang, L; Kaneko, G; Rao, J; Rich, K; Sanganahalli, BG; Taylor, JR; Wang, H	1
Fenton, AA; O'Reilly, KC; Perica, MI	1
Akbari, M; Beyer, C; Eqlimi, E; Mortezaee, K; Omidi, A; Ragerdi Kashani, I; Zendedel, A	1
Babinska, Z; Carlo Altamura, A; Cremaschi, L; D'Addario, C; Dell'Osso, B; Di Bartolomeo, M; Drago, F; Maccarrone, M; Micale, V; Palazzo, M; Pucci, M; Stark, T; Sulcova, A	1
Ferguson, BR; Gao, WJ; Gulchina, Y; Hu, XQ; Li, F; Li, ML; Li, YC; Monaco, SA; Xing, B	1
Bártová, E; Dekker, FJ; Dražanová, E; Kašpárek, T; Komůrková, D; Kozubek, S; Krejčí, J; Legartová, S; Mechoulam, R; Micale, V; Rudá-Kučerová, J; Seiser, C; Štark, T; Šulcová, A; Szymanski, W; Večeřa, J; Weitzer, G	1
Fan, QY; Fazio, V; Hallene, K; Janigro, D; Marchi, N; Ramakrishna, S	1
Grace, AA; Lodge, DJ	4
Kisby, G; Palmer, V; Spencer, PS	1
Behrens, MM; Grace, AA; Lodge, DJ	1
Chu, K; Jung, KH; Kang, KM; Kim, JH; Kim, M; Lee, SK; Lee, ST; Park, HK; Park, KI; Roh, JK	1
Jay, TM; Krebs, MO; Le Pen, G	1
Balosso, S; Battaglia, G; Carriero, G; Colciaghi, F; Finardi, A; Frasca, A; Locatelli, D; Nobili, P; Vezzani, A	1
Cotel, MC; Edgar, DM; Jones, MW; McCarthy, AP; O'Neill, MJ; Phillips, KG; Tricklebank, M; Wafford, KA	1
Aras, S; Cook, JM; Gill, KM; Grace, AA; Lodge, DJ	1
Collingridge, GL; Cotel, MC; O'Neill, MJ; Sanderson, TM; Sher, E; Tricklebank, MD	1
Cifelli, P; Gill, KM; Grace, AA; Valenti, O	1
Doisy, ET; Jürgen Wenzel, H; Schwartzkroin, PA; Tschuluun, N	1
Bahn, S; Cheng, TM; Collingridge, GL; Fitzjohn, SM; Guest, PC; Harris, LW; Holmes, E; Hradetzky, E; Lakics, V; Malik, N; O'Neill, MJ; Rahmoune, H; Sanderson, TM; Schoeffmann, S; Sher, E; Sherwood, JL; Tricklebank, MD; Tsang, TM	1
Schwartzkroin, PA; Wenzel, HJ	1
Belujon, P; Grace, AA; Patton, MH	2
Asher, A; Lodge, DJ; Perez, SM; Shah, A	1
Lodge, DJ; Shah, A	1
Baraban, SC; Calcagnotto, ME; Paredes, MF	1
Baraban, SC; Barbaro, NM; Smyth, MD	1
Baraban, SC; Calcagnotto, ME	2
Bigl, V; Rossner, S	1
Bassanini, S; Battaglia, G; Cattabeni, F; Di Luca, M; Pagliardini, S; Saglietti, L; Setola, V	1
Bassanini, S; Battaglia, G; Cattabeni, F; Di Luca, M; Gardoni, F; Pagliardini, S; Setola, V	1
Feldon, J; Jongen-Rêlo, AL; Leng, A; Lüber, M; Pothuizen, HH; Weber, L	1
Bae, YC; Cho, JH; Choi, BJ; Choi, IS; Jung, SC; Kim, JH; Lee, MG	1
Gourevitch, R; Jay, TM; Krebs, MO; Le Pen, G; Rocher, C	1
Cortez, MA; McKerlie, C; Serbanescu, I; Snead, OC	1
Didriksen, M; Flagstad, P; Glenthøj, BY	1
Arnfred, S; Cumming, P; Gjedde, A; Hansen, AK; Hemmingsen, R; Jelsing, J; Olsen, AK; Pakkenberg, B	1
Corfas, G; Gierdalski, M; Juliano, SL; Sardi, SP	1
Didriksen, M; Flagstad, P; Leist, M; Michael-Titus, AT; Penschuck, S	1
Baraban, SC; Paredes, M; Pleasure, SJ	1
Geyer, MA; Ghajarnia, M; Grace, AA; Jentsch, JD; Moore, H	1
Baraban, SC; Berger, O; Li, G; Paredes, MF; Pleasure, SJ	1
Gourevitch, R; Hazane, F; Hoareau, C; Jay, TM; Krebs, MO; Le Pen, G	1
Bassanini, S; Battaglia, G; Caccia, S; Chimenti, S; Gagliardi, B; Guiso, G; Marchi, N; Noé, F; Ravizza, T; Rizzi, M; Vezzani, A	1
Featherstone, RE; Fletcher, PJ; Kapur, S; Nobrega, JN; Rizos, Z	1
Baraban, SC; Harrington, EP; Möddel, G; Najm, IM	1
Chessel, A; Garcia, R; Krebs, MO; Le Pen, G; Léna, I	1
Bassanini, S; Battaglia, G; Cipolla, M; Finardi, A; Hallene, K; Janigro, D; Santaguida, S	1
Falsig, J; Geist, MA; Leist, M; Podhorna, J; Volbracht, C	1
Juliano, SL; Schaefer, AW	1
Dumas, RM; Fernandez, K; Haddad, RK; Vorhees, CV	1
de Feo, MR; Mecarelli, O; Ricci, GF	1
Lam, LK; Zhang, J	1
Abcarian, H; Kako, H; Misumi, A; Nelson, RL; Nelson, TM; Rizk, S; Sky-Peck, H	1
Alabaster, O; Nikula, KJ; Shivapurkar, N; Tanaka, T; Tang, ZC	1
Hara, A; Mori, H; Nagao, M; Nakagama, H; Sugimura, T; Suzui, M; Ushijima, T; Yoshimi, N	1
Germano, IM; Sperber, EF	1
Koch, T; Korf, J; Talamini, LM; Ter Horst, GJ	1
Avanzini, G; Battaglia, G; Cattabeni, F; Colacitti, C; Di Luca, M; Franceschetti, S; Sancini, G; Spreafico, R	1
Baraban, SC; Ben-Ari, Y; Chevassus-au-Louis, N; Gaïarsa, JL	1
Aloe, L; Angelucci, F; Fiore, M; Koch, T; Korf, J; Talamini, L	1
Jacobs, KM; Kharazia, VN; Prince, DA	1
Baraban, SC; Castro, PA; Cooper, EC; Lowenstein, DH	1
Davies, P; Minger, SL	2
Batshaw, ML; Hyman, SL; Mercugliano, M	1
Ding, JL; Hee, PL; Lam, TJ	1
Archer, T; Fredriksson, A; Jonsson, G; Lewander, T; Luthman, J; Söderberg, U; Sundström, E	1
Fournie, JW; Hawkins, WE; Overstreet, RM; Walker, WW	1
Abbracchio, MP; Balduini, W; Cattabeni, F; Cecchini, T; Cimino, M; Gazzanelli, GC; Lombardelli, G; Peruzzi, G	1

Reviews

9 review(s) available for methylazoxymethanol acetate and Disease Models, Animal

Article	Year
Insights on current and novel antipsychotic mechanisms from the MAM model of schizophrenia. Neuropharmacology, 2020, Volume: 163 Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Hippocampus; Male; Methylazoxymethanol Acetate; Mice; Rats; Schizophrenia; Ventral Tegmental Area	2020
Translating the MAM model of psychosis to humans. Trends in neurosciences, 2015, Volume: 38, Issue:3 Topics: Animals; Brain; Disease Models, Animal; Humans; Methylazoxymethanol Acetate; Psychotic Disorders	2015
Developmental pathways of motor dysfunction. Developmental psychobiology, 2015, Volume: 57, Issue:4 Topics: Animals; Brain; Disease Models, Animal; Female; Guinea Pigs; Methylazoxymethanol Acetate; Mice; Motor Skills Disorders; Pregnancy; Prenatal Exposure Delayed Effects; Rats	2015
Adolescence as a period of vulnerability and intervention in schizophrenia: Insights from the MAM model. Neuroscience and biobehavioral reviews, 2016, Volume: 70 Topics: Adolescent; Animals; Brain; Disease Models, Animal; Dopamine; Humans; Methylazoxymethanol Acetate; Rats; Schizophrenia	2016
Hippocampal dysfunction and disruption of dopamine system regulation in an animal model of schizophrenia. Neurotoxicity research, 2008, Volume: 14, Issue:2-3 Topics: Animals; Disease Models, Animal; Dopamine; Female; Gestational Age; Hippocampus; Humans; Methylazoxymethanol Acetate; Neural Pathways; Nucleic Acid Synthesis Inhibitors; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Schizophrenia; Signal Transduction	2008
Are developmental dysplastic lesions epileptogenic? Epilepsia, 2012, Volume: 53 Suppl 1 Topics: Animals; Carcinogens; Disease Models, Animal; Epilepsy; Female; Humans; Malformations of Cortical Development; Methylazoxymethanol Acetate; Mice; Mice, Knockout; Phosphotransferases; Pregnancy; Rats; Tuberous Sclerosis	2012
Amyloid precursor protein processing in vivo--insights from a chemically-induced constitutive overactivation of protein kinase C in Guinea pig brain. Current medicinal chemistry, 2003, Volume: 10, Issue:10 Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Brain Diseases; Disease Models, Animal; Endopeptidases; Enzyme Activation; Female; Guinea Pigs; Isoenzymes; Methylazoxymethanol Acetate; Microcephaly; Mutation; Peptide Hydrolases; Pregnancy; Protein Kinase C; Protein Processing, Post-Translational	2003
Cortical malformations and epilepsy: new insights from animal models. Epilepsia, 1999, Volume: 40, Issue:7 Topics: Abnormalities, Drug-Induced; Animals; Cerebral Cortex; Disease Models, Animal; Epilepsy; Hippocampus; Humans; Methylazoxymethanol Acetate; Mice; Mice, Knockout; Mitosis; Mutation; Nervous System Malformations; Neural Conduction; Neural Pathways; Rats; Rats, Mutant Strains; Teratogens	1999
Mechanisms underlying epileptogenesis in cortical malformations. Epilepsy research, 1999, Volume: 36, Issue:2-3 Topics: Abnormalities, Drug-Induced; Animals; Cerebral Cortex; Disease Models, Animal; Epilepsy; Humans; Methylazoxymethanol Acetate; Nucleic Acid Synthesis Inhibitors; Synaptic Transmission	1999

Other Studies

137 other study(ies) available for methylazoxymethanol acetate and Disease Models, Animal

Article	Year
Nicotine Administration Normalizes Behavioral and Neurophysiological Perturbations in the MAM Rodent Model of Schizophrenia. The international journal of neuropsychopharmacology, 2021, 12-08, Volume: 24, Issue:12 Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Hippocampus; Male; Methylazoxymethanol Acetate; Nicotine; Prepulse Inhibition; Rats; Rats, Sprague-Dawley; Schizophrenia; Self Medication; Ventral Tegmental Area	2021
GABA Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2022, Volume: 47, Issue:3 Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Hippocampus; Methylazoxymethanol Acetate; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2022
LY395756 promotes NR2B expression via activation of AKT/CREB signaling in the juvenile methylazoxymethanol mice model of schizophrenia. Brain and behavior, 2022, Volume: 12, Issue:2 Topics: Amino Acids, Dicarboxylic; Animals; Bridged Bicyclo Compounds; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Methylazoxymethanol Acetate; Mice; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Signal Transduction	2022
Early Blockade of CB1 Receptors Ameliorates Schizophrenia-like Alterations in the Neurodevelopmental MAM Model of Schizophrenia. Biomolecules, 2022, 01-10, Volume: 12, Issue:1 Topics: Animals; Disease Models, Animal; Female; Methylazoxymethanol Acetate; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Schizophrenia	2022
Use of prepubertal environment enrichment to prevent dopamine dysregulation in a neurodevelopmental rat model of schizophrenia risk. STAR protocols, 2022, 03-18, Volume: 3, Issue:1 Topics: Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Female; Male; Methylazoxymethanol Acetate; Pregnancy; Rats; Schizophrenia	2022
Congenital blindness does not protect against a schizophrenia-related phenotype in rodents. Schizophrenia research, 2023, Volume: 258 Topics: Animals; Blindness; Corticosterone; Disease Models, Animal; Female; Male; Methylazoxymethanol Acetate; Phenotype; Rats; Rats, Sprague-Dawley; Rodentia; Schizophrenia	2023
Cognitive performance of the MAM-E17 schizophrenia model rats in different age-periods. Behavioural brain research, 2020, 02-03, Volume: 379 Topics: Age Factors; Animals; Behavior, Animal; Cognitive Dysfunction; Disease Models, Animal; Female; Hippocampus; Male; Maze Learning; Memory, Short-Term; Methylazoxymethanol Acetate; Neurotoxins; Rats; Rats, Wistar; Reward; Schizophrenia; Sexual Maturation	2020
A Network Analysis of Epigenetic and Transcriptional Regulation in a Neurodevelopmental Rat Model of Schizophrenia With Implications for Translational Research. Schizophrenia bulletin, 2020, 04-10, Volume: 46, Issue:3 Topics: Adult; Animals; Disease Models, Animal; Epigenesis, Genetic; Female; Hippocampus; Humans; Male; Methylazoxymethanol Acetate; MicroRNAs; Neurodevelopmental Disorders; Neurotoxins; Prefrontal Cortex; Pregnancy; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; RNA, Messenger; Schizophrenia; Sequence Analysis, RNA; Transcription, Genetic; Translational Research, Biomedical	2020
Memory deterioration based on the tobacco smoke exposure and methylazoxymethanol acetate administration vs. aripiprazole, olanzapine and enrichment environment conditions. Pharmacology, biochemistry, and behavior, 2020, Volume: 189 Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Cognition; Disease Models, Animal; Female; Male; Methylazoxymethanol Acetate; Morris Water Maze Test; Neurotoxins; Olanzapine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Schizophrenia; Spatial Memory; Tobacco Smoke Pollution; Treatment Outcome	2020
Social dysfunction in the neurodevelopmental model of schizophrenia in male and female rats: Behavioural and biochemical studies. Neuropharmacology, 2020, 06-15, Volume: 170 Topics: Animals; Disease Models, Animal; Female; Male; Methylazoxymethanol Acetate; Neurotoxins; Oxytocin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Oxytocin; Schizophrenia; Schizophrenic Psychology; Social Behavior; Vocalization, Animal	2020
Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment. Biochemical pharmacology, 2020, Volume: 177 Topics: Animals; Antipsychotic Agents; Brain; Cannabidiol; Cerebrovascular Circulation; Disease Models, Animal; Female; Gene Expression Regulation; Haloperidol; Magnetic Resonance Imaging; Male; Methylazoxymethanol Acetate; Models, Molecular; Molecular Dynamics Simulation; Pregnancy; Prenatal Exposure Delayed Effects; Puberty; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Schizophrenia	2020
Developmental alterations in the transcriptome of three distinct rodent models of schizophrenia. PloS one, 2020, Volume: 15, Issue:6 Topics: Animals; Behavior, Animal; Disease Models, Animal; Female; Gene Expression Profiling; Growth and Development; Hippocampus; Malnutrition; Methylazoxymethanol Acetate; Poly I-C; Pregnancy; Rats; Rats, Sprague-Dawley; Schizophrenia	2020
Metabolic profile of methylazoxymethanol model of schizophrenia in rats and effects of three antipsychotics in long-acting formulation. Toxicology and applied pharmacology, 2020, 11-01, Volume: 406 Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Female; Haloperidol; Lipid Metabolism; Male; Metabolome; Methylazoxymethanol Acetate; Olanzapine; Rats, Sprague-Dawley; Risperidone; Schizophrenia	2020
Interacting effects of the MAM model of schizophrenia and antipsychotic treatment: Untargeted proteomics approach in adipose tissue. Progress in neuro-psychopharmacology & biological psychiatry, 2021, 06-08, Volume: 108 Topics: Adipose Tissue; Animals; Antipsychotic Agents; Disease Models, Animal; Female; Haloperidol; Intra-Abdominal Fat; Methylazoxymethanol Acetate; Olanzapine; Pregnancy; Prenatal Exposure Delayed Effects; Proteomics; Rats; Rats, Sprague-Dawley; Risperidone; Schizophrenia; Signal Transduction; TOR Serine-Threonine Kinases	2021
Prepubertal Environmental Enrichment Prevents Dopamine Dysregulation and Hippocampal Hyperactivity in MAM Schizophrenia Model Rats. Biological psychiatry, 2021, 02-01, Volume: 89, Issue:3 Topics: Animals; Disease Models, Animal; Dopamine; Hippocampus; Methylazoxymethanol Acetate; Rats; Rats, Sprague-Dawley; Schizophrenia	2021
Diminished excitatory synaptic transmission correlates with impaired spatial working memory in neurodevelopmental rodent models of schizophrenia. Pharmacology, biochemistry, and behavior, 2021, Volume: 202 Topics: Animals; Behavior, Animal; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; Male; Memory, Short-Term; Methylazoxymethanol Acetate; Mice; Mice, Inbred C57BL; Neurodevelopmental Disorders; Prefrontal Cortex; Pregnancy; Pyramidal Cells; Schizophrenia; Schizophrenic Psychology; Social Isolation; Spatial Memory; Synaptic Transmission	2021
Peripubertal mGluR2/3 Agonist Treatment Prevents Hippocampal Dysfunction and Dopamine System Hyperactivity in Adulthood in MAM Model of Schizophrenia. Schizophrenia bulletin, 2021, 10-21, Volume: 47, Issue:6 Topics: Age Factors; Amino Acids; Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Agonists; Hippocampus; Male; Methylazoxymethanol Acetate; Neurotoxins; Rats; Receptors, Metabotropic Glutamate; Schizophrenia; Ventral Tegmental Area	2021
Thalamic reticular nucleus impairments and abnormal prefrontal control of dopamine system in a developmental model of schizophrenia: prevention by N-acetylcysteine. Molecular psychiatry, 2021, Volume: 26, Issue:12 Topics: Acetylcysteine; Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Methylazoxymethanol Acetate; Rats; Schizophrenia; Thalamic Nuclei	2021
Reduced risk aversion and impaired short-term memory in juvenile rats with malformation of cortical development. Behavioural brain research, 2021, 08-27, Volume: 412 Topics: Affect; Animals; Anxiety; Behavior, Animal; Brain; Cognition; Cues; Disease Models, Animal; Female; Hippocampus; Male; Malformations of Cortical Development; Maze Learning; Memory, Short-Term; Methylazoxymethanol Acetate; Motor Activity; Neurogenesis; Rats; Rats, Sprague-Dawley; Risk Reduction Behavior; Risk-Taking; Spatial Memory	2021
Inhibition of BET Proteins during Adolescence Affects Prefrontal Cortical Development: Relevance to Schizophrenia. International journal of molecular sciences, 2021, Aug-13, Volume: 22, Issue:16 Topics: Adolescent; Adolescent Development; Animals; Azepines; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Humans; Long-Term Potentiation; Male; Methylazoxymethanol Acetate; Prefrontal Cortex; Proteomics; Rats; Recognition, Psychology; Schizophrenia; Sex Characteristics; Triazoles	2021
Suppression of Methamphetamine Self-Administration by Ketamine Pre-treatment Is Absent in the Methylazoxymethanol (MAM) Rat Model of Schizophrenia. Neurotoxicity research, 2017, Volume: 32, Issue:1 Topics: Analysis of Variance; Animals; Central Nervous System Stimulants; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Ketamine; Locomotion; Methamphetamine; Methylazoxymethanol Acetate; Rats; Rats, Sprague-Dawley; Schizophrenia; Self Administration	2017
The MAM-E17 schizophrenia rat model: Comprehensive behavioral analysis of pre-pubertal, pubertal and adult rats. Behavioural brain research, 2017, 08-14, Volume: 332 Topics: Aging; Animals; Anxiety; Disease Models, Animal; Exploratory Behavior; Female; Hippocampus; Male; Methylazoxymethanol Acetate; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Prepulse Inhibition; Rats, Wistar; Rotarod Performance Test; Schizophrenia; Schizophrenic Psychology	2017
Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia. Journal of neurochemistry, 2017, Volume: 143, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cognition Disorders; Disease Models, Animal; Epigenesis, Genetic; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation, Developmental; In Vitro Techniques; Male; Methylazoxymethanol Acetate; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2017
MAM-E17 rat model impairments on a novel continuous performance task: effects of potential cognitive enhancing drugs. Psychopharmacology, 2017, Volume: 234, Issue:19 Topics: Animals; Attention; Cognition; Disease Models, Animal; Executive Function; Male; Methylazoxymethanol Acetate; Neurotoxins; Nootropic Agents; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Schizophrenia; Treatment Outcome	2017
The methylazoxymethanol acetate rat model: molecular and epigenetic effect in the developing prefrontal cortex: An Editorial Highlight for 'Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM Journal of neurochemistry, 2017, Volume: 143, Issue:3 Topics: Animals; Disease Models, Animal; Epigenesis, Genetic; Female; Methylazoxymethanol Acetate; Neurotoxins; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Schizophrenia	2017
Impaired contextual fear-conditioning in MAM rodent model of schizophrenia. Schizophrenia research, 2018, Volume: 195 Topics: Action Potentials; Amphetamine; Animals; Central Nervous System Stimulants; Conditioning, Classical; Disease Models, Animal; Dopaminergic Neurons; Fear; Female; Learning Disabilities; Locomotion; Male; Methylazoxymethanol Acetate; Neurotoxins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Schizophrenia; Time Factors; Ventral Tegmental Area	2018
Adolescent environmental enrichment prevents the emergence of schizophrenia-like abnormalities in a neurodevelopmental model of schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2018, Volume: 28, Issue:1 Topics: Animals; Disease Models, Animal; Environment; Histones; Housing, Animal; Male; Methylazoxymethanol Acetate; Prefrontal Cortex; Random Allocation; Rats, Wistar; Schizophrenia; Schizophrenic Psychology; Sexual Maturation; Site-Specific DNA-Methyltransferase (Adenine-Specific)	2018
Ablation of aberrant neurogenesis fails to attenuate cognitive deficit of chronically epileptic mice. Epilepsy research, 2018, Volume: 142 Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Cognition Disorders; Disease Models, Animal; Doublecortin Domain Proteins; Green Fluorescent Proteins; Hippocampus; Homeodomain Proteins; Ki-67 Antigen; Male; Maze Learning; Methylazoxymethanol Acetate; Mice; Microtubule-Associated Proteins; Muscarinic Agonists; Neurogenesis; Neuropeptides; Pilocarpine; Proto-Oncogene Proteins c-fos; Status Epilepticus; Transduction, Genetic; Tumor Suppressor Proteins	2018
Adolescent Social Isolation Affects Schizophrenia-Like Behavior in the MAM-E17 Model of Schizophrenia. Neurotoxicity research, 2018, Volume: 34, Issue:2 Topics: Age Factors; Animals; Carcinogens; Disease Models, Animal; Embryo, Mammalian; Female; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Interpersonal Relations; Locomotion; Methylazoxymethanol Acetate; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Recognition, Psychology; Schizophrenia; Schizophrenic Psychology; Sensory Gating; Social Isolation; Statistics, Nonparametric	2018
Therapeutic effect of perinatal exogenous melatonin on behavioral and histopathological changes and antioxidative enzymes in neonate mouse model of cortical malformation. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2018, Volume: 68 Topics: Animals; Animals, Newborn; Antioxidants; Carcinogens; Catalase; Disease Models, Animal; Exploratory Behavior; Female; Gene Expression Regulation, Developmental; Glutathione Peroxidase; Intermediate Filaments; Malformations of Cortical Development; Malondialdehyde; Maze Learning; Melatonin; Methylazoxymethanol Acetate; Mice; Mice, Inbred BALB C; Nitroprusside; Pregnancy; Prenatal Exposure Delayed Effects; Superoxide Dismutase; Tryptamines	2018
α7 Nicotinic receptor-modulating agents reverse the hyperdopaminergic tone in the MAM model of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:8 Topics: Action Potentials; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Basolateral Nuclear Complex; Disease Models, Animal; Dopaminergic Neurons; Hippocampus; Male; Methylazoxymethanol Acetate; Random Allocation; Rats, Sprague-Dawley; Schizophrenia; Ventral Tegmental Area	2018
Altered brain cannabinoid 1 receptor mRNA expression across postnatal development in the MAM model of schizophrenia. Schizophrenia research, 2018, Volume: 201 Topics: Animals; Brain; Disease Models, Animal; Gene Expression Regulation, Developmental; In Situ Hybridization; Male; Methylazoxymethanol Acetate; Random Allocation; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; RNA, Messenger; Schizophrenia	2018
Juvenile treatment with mGluR2/3 agonist prevents schizophrenia-like phenotypes in adult by acting through GSK3β. Neuropharmacology, 2018, 07-15, Volume: 137 Topics: Amino Acids; Animals; Antipsychotic Agents; Bridged Bicyclo Compounds, Heterocyclic; Dendritic Spines; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Glycogen Synthase Kinase 3 beta; Learning Disabilities; Methylazoxymethanol Acetate; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Schizophrenia; Tissue Culture Techniques	2018
Sub-circuit alterations in dorsal hippocampus structure and function after global neurodevelopmental insult. Brain structure & function, 2018, Volume: 223, Issue:8 Topics: Animals; Disease Models, Animal; Epilepsy; Female; Hippocampus; Male; Membrane Potentials; Methylazoxymethanol Acetate; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Long-Evans; Schizophrenia; Synapses	2018
Abnormalities in behaviour, histology and prefrontal cortical gene expression profiles relevant to schizophrenia in embryonic day 17 MAM-Exposed C57BL/6 mice. Neuropharmacology, 2018, 09-15, Volume: 140 Topics: Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertrophy; Lateral Ventricles; Male; Methylazoxymethanol Acetate; Mice; Mice, Inbred C57BL; Motor Activity; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Prepulse Inhibition; Schizophrenia; Schizophrenic Psychology; Sex Characteristics; Social Behavior; Transcriptome	2018
State-dependent effects of the D Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:3 Topics: Animals; Apomorphine; Aripiprazole; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopaminergic Neurons; Electroencephalography; Haloperidol; Male; Methylazoxymethanol Acetate; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Ventral Tegmental Area	2019
Development of the MAM model of schizophrenia in mice: Sex similarities and differences of hippocampal and prefrontal cortical function. Neuropharmacology, 2019, Volume: 144 Topics: Animals; Auditory Perception; Disease Models, Animal; Fear; Female; Hippocampus; Long-Term Potentiation; Male; Memory; Methylazoxymethanol Acetate; Mice; Mice, Inbred C57BL; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Prepulse Inhibition; Proteome; Reflex, Startle; Schizophrenia; Schizophrenic Psychology; Sex Characteristics	2019
Evaluation of ultrasonic vocalizations in a neurodevelopmental model of schizophrenia during the early life stages of rats. Neuropharmacology, 2019, 03-01, Volume: 146 Topics: Animals; Disease Models, Animal; Female; Male; Methylazoxymethanol Acetate; Pregnancy; Rats; Schizophrenia; Social Behavior; Ultrasonics; Vocalization, Animal	2019
Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia. Neuropharmacology, 2019, 03-01, Volume: 146 Topics: Amides; Animals; Arachidonic Acids; Cannabidiol; Disease Models, Animal; Endocannabinoids; Ethanolamines; Female; Glycerides; Hippocampus; Interpersonal Relations; Male; Methylazoxymethanol Acetate; Motor Activity; Oleic Acids; Palmitic Acids; Piperidines; Polyunsaturated Alkamides; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Puberty; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Recognition, Psychology; RNA, Messenger; Schizophrenia	2019
Effect of estrous cycle on schizophrenia-like behaviors in MAM exposed rats. Behavioural brain research, 2019, 04-19, Volume: 362 Topics: Amphetamine; Animals; Behavior, Animal; Disease Models, Animal; Estrous Cycle; Female; Hippocampus; Methylazoxymethanol Acetate; Parvalbumins; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Schizophrenia; Sensory Gating	2019
Prenatal treatment with methylazoxymethanol acetate as a neurodevelopmental disruption model of schizophrenia in mice. Neuropharmacology, 2019, 05-15, Volume: 150 Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Clozapine; Disease Models, Animal; Female; Haloperidol; Hippocampus; Methylazoxymethanol Acetate; Mice; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Prepulse Inhibition; Risperidone; Schizophrenia	2019
Nicotine Self-administration Is Not Increased in the Methylazoxymethanol Acetate Rodent Model of Schizophrenia. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2020, 02-06, Volume: 22, Issue:2 Topics: Animals; Animals, Newborn; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Male; Methylazoxymethanol Acetate; Nicotine; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Schizophrenia; Self Administration; Sucrose	2020
Different effects of prenatal MAM vs. perinatal THC exposure on regional cerebral blood perfusion detected by Arterial Spin Labelling MRI in rats. Scientific reports, 2019, 04-15, Volume: 9, Issue:1 Topics: Animals; Behavior Observation Techniques; Cerebrovascular Circulation; Circle of Willis; Disease Models, Animal; Dronabinol; Female; Hippocampus; Humans; Magnetic Resonance Angiography; Male; Methylazoxymethanol Acetate; Neurogenesis; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Schizophrenia; Sensorimotor Cortex	2019
Targeting PSD95-nNOS interaction by Tat-N-dimer peptide during status epilepticus is neuroprotective in MAM-pilocarpine rat model. Neuropharmacology, 2019, 07-15, Volume: 153 Topics: Animals; Disease Models, Animal; Disks Large Homolog 4 Protein; Female; Methylazoxymethanol Acetate; Neuroprotective Agents; Nitric Oxide Synthase Type I; Peptides; Pilocarpine; Pregnancy; Protein Binding; Random Allocation; Rats; Rats, Sprague-Dawley; Status Epilepticus	2019
The MAM rodent model of schizophrenia. Current protocols in neuroscience, 2013, Volume: Chapter 9 Topics: Animals; Brain; Clinical Protocols; Disease Models, Animal; Female; Fetal Development; Male; Methylazoxymethanol Acetate; Neurotoxins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Schizophrenia	2013
Altered migratory behavior of interneurons in a model of cortical dysplasia: the influence of elevated GABAA activity. Cerebral cortex (New York, N.Y. : 1991), 2014, Volume: 24, Issue:9 Topics: Animals; Blotting, Western; Cell Movement; Disease Models, Animal; Ferrets; GABA-A Receptor Antagonists; Interneurons; K Cl- Cotransporters; Malformations of Cortical Development; Methylazoxymethanol Acetate; Neocortex; Receptors, GABA-A; Symporters; Tissue Culture Techniques; Video Recording	2014
A sensitive period for GABAergic interneurons in the dentate gyrus in modulating sensorimotor gating. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Apr-10, Volume: 33, Issue:15 Topics: Age Factors; Animals; Behavior, Animal; Critical Period, Psychological; Dendrites; Dentate Gyrus; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin-Like Kinases; Drug Interactions; Environment; GABA Agonists; GABAergic Neurons; Inhibition, Psychological; Interneurons; Intracellular Signaling Peptides and Proteins; Male; Methylazoxymethanol Acetate; Mice; Mice, Inbred C57BL; Microinjections; Microtubule-Associated Proteins; Muscimol; Neurogenesis; Neuropeptides; Prefrontal Cortex; Protein Serine-Threonine Kinases; Schizophrenia; Sensory Gating	2013
Fine-tuning of neurogenesis is essential for the evolutionary expansion of the cerebral cortex. Cerebral cortex (New York, N.Y. : 1991), 2015, Volume: 25, Issue:2 Topics: Animals; Animals, Newborn; Biological Evolution; Disease Models, Animal; Eye Proteins; Ferrets; Homeodomain Proteins; Lissencephaly; Methylazoxymethanol Acetate; Mice; Neural Stem Cells; Neurogenesis; Neuroglia; Neurons; Paired Box Transcription Factors; Parietal Lobe; PAX6 Transcription Factor; Repressor Proteins; Stem Cell Niche; Temporal Lobe	2015
Hippocampal interneuron transplants reverse aberrant dopamine system function and behavior in a rodent model of schizophrenia. Molecular psychiatry, 2013, Volume: 18, Issue:11 Topics: Action Potentials; Amphetamine; Animals; Disease Models, Animal; Dopaminergic Neurons; Female; Hippocampus; Interneurons; Male; Median Eminence; Methylazoxymethanol Acetate; Motor Activity; Rats; Schizophrenia	2013
Targeted disruption of layer 4 during development increases GABAA receptor neurotransmission in the neocortex. Journal of neurophysiology, 2014, Volume: 111, Issue:2 Topics: Animals; Disease Models, Animal; Female; Ferrets; Inhibitory Postsynaptic Potentials; Malformations of Cortical Development; Methylazoxymethanol Acetate; Miniature Postsynaptic Potentials; Neocortex; Pregnancy; Protein Subunits; Pyramidal Cells; Receptors, GABA-A; Teratogens	2014
Prior antipsychotic drug treatment prevents response to novel antipsychotic agent in the methylazoxymethanol acetate model of schizophrenia. Schizophrenia bulletin, 2014, Volume: 40, Issue:2 Topics: Allosteric Regulation; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Diazepam; Disease Models, Animal; Dopamine; Dopamine Agents; Dopaminergic Neurons; Drug Interactions; Female; GABA Agonists; Haloperidol; Hippocampus; Imidazoles; Locomotion; Male; Methylazoxymethanol Acetate; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Schizophrenia; Sodium Chloride; Substance Withdrawal Syndrome; Ventral Tegmental Area	2014
An augmented dopamine system function is present prior to puberty in the methylazoxymethanol acetate rodent model of schizophrenia. Developmental neurobiology, 2014, Volume: 74, Issue:9 Topics: Action Potentials; Amphetamine; Animals; Disease Models, Animal; Dopamine; Dopamine Agents; Dopaminergic Neurons; Dose-Response Relationship, Drug; Hippocampus; Methylazoxymethanol Acetate; Motor Activity; Neural Pathways; Parvalbumins; Pedunculopontine Tegmental Nucleus; Rats, Sprague-Dawley; Schizophrenia; Sexual Maturation; Ventral Tegmental Area	2014
Corresponding decrease in neuronal markers signals progressive parvalbumin neuron loss in MAM schizophrenia model. The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:10 Topics: Age Factors; Analysis of Variance; Animals; Cell Death; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Methylazoxymethanol Acetate; Neurons; Neurotoxins; Parvalbumins; Rats; Receptors, Neurokinin-1; Schizophrenia	2014
Alterations in dopamine system function across the estrous cycle of the MAM rodent model of schizophrenia. Psychoneuroendocrinology, 2014, Volume: 47 Topics: Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Estrous Cycle; Female; Humans; Male; Methylazoxymethanol Acetate; Pregnancy; Rats; Rats, Sprague-Dawley; Schizophrenia; Signal Transduction; Vaginal Smears	2014
Vagal nerve stimulation reverses aberrant dopamine system function in the methylazoxymethanol acetate rodent model of schizophrenia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Jul-09, Volume: 34, Issue:28 Topics: Action Potentials; Animals; Disease Models, Animal; Dopaminergic Neurons; Hippocampus; Humans; Male; Methylazoxymethanol Acetate; Neurotoxins; Rats; Rats, Sprague-Dawley; Schizophrenia; Treatment Outcome; Vagus Nerve Stimulation	2014
Social interaction rescues memory deficit in an animal model of Alzheimer's disease by increasing BDNF-dependent hippocampal neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Dec-03, Volume: 34, Issue:49 Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Dentate Gyrus; Diphtheria Toxin; Disease Models, Animal; Flavones; Gene Knockdown Techniques; Hippocampus; Housing, Animal; Male; Memory Disorders; Methylazoxymethanol Acetate; Mice; Mice, Transgenic; Neurogenesis; Presenilin-1; Social Behavior	2014
Effects of pubertal cannabinoid administration on attentional set-shifting and dopaminergic hyper-responsivity in a developmental disruption model of schizophrenia. The international journal of neuropsychopharmacology, 2014, Dec-13, Volume: 18, Issue:2 Topics: Amphetamine; Animals; Attention; Benzoxazines; Cannabinoids; Central Nervous System Stimulants; Disease Models, Animal; Dopaminergic Neurons; Executive Function; Female; Male; Methylazoxymethanol Acetate; Morpholines; Motor Activity; Naphthalenes; Neuropsychological Tests; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Schizophrenia; Schizophrenic Psychology; Ventral Tegmental Area	2014
Standard dose valproic acid does not cause additional cognitive impact in a rodent model of intractable epilepsy. Epilepsy research, 2015, Volume: 110 Topics: Animals; Animals, Newborn; Anticonvulsants; Cognition; Cognition Disorders; Disease Models, Animal; Epilepsy; Female; Flurothyl; Hippocampus; Malformations of Cortical Development; Maze Learning; Methylazoxymethanol Acetate; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Sprague-Dawley; Seizures; Survival Analysis; Valproic Acid	2015
Alterations in spatial memory and anxiety in the MAM E17 rat model of hippocampal pathology in schizophrenia. Psychopharmacology, 2015, Volume: 232, Issue:21-22 Topics: Animals; Anxiety; Disease Models, Animal; Hippocampus; Male; Memory, Short-Term; Methylazoxymethanol Acetate; Rats; Schizophrenia; Spatial Memory	2015
Aberrant high frequency oscillations recorded in the rat nucleus accumbens in the methylazoxymethanol acetate neurodevelopmental model of schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry, 2015, Aug-03, Volume: 61 Topics: Animals; Antipsychotic Agents; Brain Waves; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; Male; Methylazoxymethanol Acetate; Neurotoxins; Nucleus Accumbens; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Schizophrenia	2015
[MAM-E17 schizophrenia rat model]. Psychiatria Hungarica : A Magyar Pszichiatriai Tarsasag tudomanyos folyoirata, 2015, Volume: 30, Issue:1 Topics: Animals; Behavior, Animal; Brain; Cognition; Disease Models, Animal; Frontal Lobe; Hippocampus; Limbic System; Locomotion; Methylazoxymethanol Acetate; Movement Disorders; Neurotoxins; Rats; Schizophrenia; Schizophrenic Psychology; Social Behavior	2015
MAM (E17) rodent developmental model of neuropsychiatric disease: disruptions in learning and dysregulation of nucleus accumbens dopamine release, but spared executive function. Psychopharmacology, 2015, Volume: 232, Issue:21-22 Topics: Amphetamine; Animals; Conditioning, Classical; Disease Models, Animal; Dopamine; Executive Function; Learning; Male; Methylazoxymethanol Acetate; Motivation; Nucleus Accumbens; Rats, Sprague-Dawley; Reward; Schizophrenia; Schizophrenic Psychology	2015
Schizophrenia-Like Phenotype Inherited by the F2 Generation of a Gestational Disruption Model of Schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:2 Topics: Animals; Disease Models, Animal; DNA Methylation; Dopaminergic Neurons; Female; Hippocampus; Male; Methylation; Methylazoxymethanol Acetate; Parvalbumins; Phenotype; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Schizophrenia; Transcription Factors; Ventral Tegmental Area	2016
Valproic acid (VPA) reduces sensorimotor gating deficits and HDAC2 overexpression in the MAM animal model of schizophrenia. Pharmacological reports : PR, 2015, Volume: 67, Issue:6 Topics: Acetylation; Animals; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Histone Deacetylase 2; Histones; Male; Methylazoxymethanol Acetate; Prefrontal Cortex; Rats; Schizophrenia; Sensory Gating; Valproic Acid	2015
Biochemical and cognitive impairments observed in animal models of schizophrenia induced by prenatal stress paradigm or methylazoxymethanol acetate administration. Acta neurobiologiae experimentalis, 2015, Volume: 75, Issue:3 Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cognition Disorders; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Escape Reaction; Female; Gestational Age; Male; Maze Learning; Methylazoxymethanol Acetate; Motor Activity; Neurotoxins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Schizophrenia	2015
Dopamine System Dysregulation and the Pathophysiology of Schizophrenia: Insights From the Methylazoxymethanol Acetate Model. Biological psychiatry, 2017, 01-01, Volume: 81, Issue:1 Topics: Animals; Brain; Disease Models, Animal; Dopamine; Humans; Methylazoxymethanol Acetate; Neurons; Rats; Schizophrenia	2017
Amygdala Hyperactivity in MAM Model of Schizophrenia is Normalized by Peripubertal Diazepam Administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:10 Topics: Action Potentials; Administration, Oral; Amygdala; Animals; Animals, Newborn; Anti-Anxiety Agents; Anxiety; Conditioning, Psychological; Diazepam; Disease Models, Animal; Fear; Female; Hippocampus; Male; Maze Learning; Methylazoxymethanol Acetate; Neurons; Neurotoxins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Schizophrenia	2016
Reactivity to addictive drugs in the methylazoxymethanol (MAM) model of schizophrenia in male and female rats. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2017, Volume: 18, Issue:2 Topics: Alcohol Drinking; Animals; Behavior, Animal; Disease Models, Animal; Female; Male; Methamphetamine; Methylazoxymethanol Acetate; Pregnancy; Rats; Rats, Sprague-Dawley; Schizophrenia; Sex Characteristics	2017
Loss of Parvalbumin in the Hippocampus of MAM Schizophrenia Model Rats Is Attenuated by Peripubertal Diazepam. The international journal of neuropsychopharmacology, 2016, Volume: 19, Issue:11 Topics: Animals; Antipsychotic Agents; Behavior, Animal; Diazepam; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Female; Gestational Age; Hippocampus; Interneurons; Methylazoxymethanol Acetate; Parvalbumins; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Schizophrenia; Schizophrenic Psychology; Sexual Maturation	2016
Hypofrontality and Posterior Hyperactivity in Early Schizophrenia: Imaging and Behavior in a Preclinical Model. Biological psychiatry, 2017, 03-15, Volume: 81, Issue:6 Topics: Animals; Behavior, Animal; Biomarkers; Brain; Decision Making; Diffusion Tensor Imaging; Disease Models, Animal; Female; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Methylazoxymethanol Acetate; Multimodal Imaging; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reversal Learning; Reward; Schizophrenia; Schizophrenic Psychology	2017
Memory deficits with intact cognitive control in the methylazoxymethanol acetate (MAM) exposure model of neurodevelopmental insult. Neurobiology of learning and memory, 2016, Volume: 134 Pt B Topics: Animals; Behavior, Animal; Disease Models, Animal; Executive Function; Female; Hippocampus; Hyperkinesis; Male; Memory Disorders; Methylazoxymethanol Acetate; Prefrontal Cortex; Pregnancy; Rats; Rats, Long-Evans; Schizophrenia; Spatial Memory	2016
Prenatal transplantation of epidermal neural crest stem cells in malformation of cortical development mouse model. Microscopy research and technique, 2017, Volume: 80, Issue:4 Topics: Animals; Calcium-Binding Proteins; Cell- and Tissue-Based Therapy; Cells, Cultured; Cerebral Cortex; Chemokine CXCL12; Chick Embryo; Corpus Callosum; Disease Models, Animal; DNA-Binding Proteins; Doublecortin Domain Proteins; Doublecortin Protein; Epithelial Cells; Female; Glial Fibrillary Acidic Protein; Hair Follicle; Homeodomain Proteins; Methylazoxymethanol Acetate; Mice; Mice, Inbred BALB C; Microfilament Proteins; Microtubule-Associated Proteins; Nerve Tissue Proteins; Nestin; Neural Crest; Neural Stem Cells; Neurogenesis; Neuropeptides; Nuclear Proteins; Pregnancy; Receptors, CXCR4; Tissue Culture Techniques	2017
A preliminary study of endocannabinoid system regulation in psychosis: Distinct alterations of CNR1 promoter DNA methylation in patients with schizophrenia. Schizophrenia research, 2017, Volume: 188 Topics: Animals; Bipolar Disorder; Cohort Studies; CpG Islands; Depressive Disorder, Major; Disease Models, Animal; DNA Methylation; Endocannabinoids; Female; Gene Expression Regulation; Humans; Leukocytes, Mononuclear; Male; Methylazoxymethanol Acetate; Middle Aged; Prefrontal Cortex; Promoter Regions, Genetic; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Schizophrenia	2017
Juvenile treatment with a novel mGluR2 agonist/mGluR3 antagonist compound, LY395756, reverses learning deficits and cognitive flexibility impairments in adults in a neurodevelopmental model of schizophrenia. Neurobiology of learning and memory, 2017, Volume: 140 Topics: Amino Acids, Dicarboxylic; Animals; Brain; Bridged Bicyclo Compounds; Cognition; Cognition Disorders; Disease Models, Animal; Learning; Methylazoxymethanol Acetate; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2017
HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animals. Journal of cellular physiology, 2018, Volume: 233, Issue:1 Topics: Acetylation; Animals; Antipsychotic Agents; Brain; Cannabinoid Receptor Antagonists; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Gestational Age; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Methylazoxymethanol Acetate; Mice, Inbred C57BL; Neural Cell Adhesion Molecules; Neurogenesis; Neurons; Protein Processing, Post-Translational; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Schizophrenia; Signal Transduction; SOXB1 Transcription Factors; Time Factors	2018
Combined effects of prenatal inhibition of vasculogenesis and neurogenesis on rat brain development. Neurobiology of disease, 2008, Volume: 32, Issue:3 Topics: Aging; Animals; Animals, Newborn; Blood Vessels; Blood-Brain Barrier; Brain; Brain Chemistry; Brain Edema; Disease Models, Animal; Gliosis; Hippocampus; Malformations of Cortical Development; Methylazoxymethanol Acetate; Mossy Fibers, Hippocampal; Neovascularization, Physiologic; Nervous System; Neurogenesis; Rats; Rats, Sprague-Dawley; Thalidomide	2008
The ALS/PDC syndrome of Guam and the cycad hypothesis. Neurology, 2009, Feb-03, Volume: 72, Issue:5 Topics: alpha-Synuclein; Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Bacterial Toxins; Causality; Cyanobacteria Toxins; Cycas; Dementia; Disease Models, Animal; Epidemiologic Research Design; Epidemiologic Studies; Flour; Guam; Hazardous Substances; Humans; Incidence; Indonesia; Japan; Marine Toxins; Methylazoxymethanol Acetate; Microcystins; Nerve Degeneration; Parkinsonian Disorders; Plant Extracts; Syndrome; Tauopathies	2009
A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Feb-25, Volume: 29, Issue:8 Topics: Analysis of Variance; Animals; Behavior, Animal; Biological Clocks; Conditioning, Psychological; Disease Models, Animal; Electroencephalography; Evoked Potentials; Fear; Female; Glutamate Decarboxylase; Hippocampus; Interneurons; Male; Methylazoxymethanol Acetate; Neural Inhibition; Neurotoxins; Parvalbumins; Prefrontal Cortex; Pregnancy; Rats; Schizophrenia; Spectrum Analysis	2009
Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia. Behavioural brain research, 2009, Dec-07, Volume: 204, Issue:2 Topics: Animals; Brain; Disease Models, Animal; Female; Hyperkinesis; Memory, Short-Term; Methylazoxymethanol Acetate; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Schizophrenia; Schizophrenic Psychology; Sensory Gating	2009
Role of cortical dysplasia in epileptogenesis following prolonged febrile seizure. Epilepsia, 2010, Volume: 51, Issue:9 Topics: Animals; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Hippocampus; Humans; Malformations of Cortical Development; Methylazoxymethanol Acetate; Mossy Fibers, Hippocampal; Rats; Rats, Sprague-Dawley; Sclerosis; Seizures, Febrile; Synapses	2010
Effect of antipsychotics on spontaneous hyperactivity and hypersensitivity to MK-801-induced hyperactivity in rats prenatally exposed to methylazoxymethanol. Journal of psychopharmacology (Oxford, England), 2011, Volume: 25, Issue:6 Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; Female; Hyperkinesis; Methylazoxymethanol Acetate; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Schizophrenia	2011
Divergent activation of ventromedial and ventrolateral dopamine systems in animal models of amphetamine sensitization and schizophrenia. The international journal of neuropsychopharmacology, 2012, Volume: 15, Issue:1 Topics: Action Potentials; Amphetamine; Animals; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Dyskinesia, Drug-Induced; Female; Male; Methylazoxymethanol Acetate; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Schizophrenia; Ventral Tegmental Area	2012
Status epilepticus-induced pathologic plasticity in a rat model of focal cortical dysplasia. Brain : a journal of neurology, 2011, Volume: 134, Issue:Pt 10 Topics: Animals; Cerebral Cortex; Disease Models, Animal; Malformations of Cortical Development; Methylazoxymethanol Acetate; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Status Epilepticus	2011
Differential effects of NMDA antagonists on high frequency and gamma EEG oscillations in a neurodevelopmental model of schizophrenia. Neuropharmacology, 2012, Volume: 62, Issue:3 Topics: Animals; Biphenyl Compounds; Brain Waves; Cerebral Cortex; Cross-Over Studies; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Male; Methylazoxymethanol Acetate; Pregnancy; Propionates; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2012
A novel α5GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:9 Topics: Allosteric Regulation; Amphetamine; Animals; Benzodiazepines; Diazepam; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Female; GABA Agonists; Hippocampus; Humans; Hyperkinesis; Imidazoles; Male; Methylazoxymethanol Acetate; Neurotoxins; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Schizophrenia; Ventral Tegmental Area	2011
Alterations in hippocampal excitability, synaptic transmission and synaptic plasticity in a neurodevelopmental model of schizophrenia. Neuropharmacology, 2012, Volume: 62, Issue:3 Topics: Animals; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; Hippocampus; Male; Methylazoxymethanol Acetate; Neuronal Plasticity; Organ Culture Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Schizophrenia; Synaptic Transmission	2012
Antipsychotic drugs rapidly induce dopamine neuron depolarization block in a developmental rat model of schizophrenia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Aug-24, Volume: 31, Issue:34 Topics: Action Potentials; Animals; Animals, Newborn; Antipsychotic Agents; Cell Polarity; Disease Models, Animal; Dopamine; Female; Inhibitory Postsynaptic Potentials; Male; Methylazoxymethanol Acetate; Neural Inhibition; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Reaction Time; Schizophrenia; Ventral Tegmental Area	2011
Initiation of epileptiform activity in a rat model of periventricular nodular heterotopia. Epilepsia, 2011, Volume: 52, Issue:12 Topics: Action Potentials; Animals; Disease Models, Animal; Epilepsy; Female; Hippocampus; In Vitro Techniques; Lysine; Male; Methylazoxymethanol Acetate; Neocortex; Neurons; Periventricular Nodular Heterotopia; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Teratogens	2011
The methylazoxymethanol acetate (MAM-E17) rat model: molecular and functional effects in the hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:2 Topics: Animals; Disease Models, Animal; Female; Frontal Lobe; Gene Expression Regulation; Hippocampus; Humans; Male; Metabolomics; Methylazoxymethanol Acetate; Pregnancy; Prenatal Exposure Delayed Effects; Proteomics; Rats; Schizophrenia; Synaptic Transmission	2012
Disruption of prefrontal cortical-hippocampal balance in a developmental model of schizophrenia: reversal by sulpiride. The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:3 Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Female; Hippocampus; Long-Term Potentiation; Male; Methylazoxymethanol Acetate; Prefrontal Cortex; Pregnancy; Rats; Rats, Sprague-Dawley; Schizophrenia; Sulpiride	2013
Hippocampal deep brain stimulation reverses physiological and behavioural deficits in a rodent model of schizophrenia. The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:6 Topics: Action Potentials; Amphetamine; Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Deep Brain Stimulation; Disease Models, Animal; Dopaminergic Neurons; Female; Hippocampus; Hyperkinesis; Male; Mental Disorders; Methylazoxymethanol Acetate; Neurotoxins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Schizophrenia; Ventral Tegmental Area	2013
Role of the prefrontal cortex in altered hippocampal-accumbens synaptic plasticity in a developmental animal model of schizophrenia. Cerebral cortex (New York, N.Y. : 1991), 2014, Volume: 24, Issue:4 Topics: Analysis of Variance; Animals; Disease Models, Animal; Female; Hippocampus; Male; Methylazoxymethanol Acetate; Neural Pathways; Neuronal Plasticity; Neurons; Neurotoxins; Nucleus Accumbens; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Schizophrenia; Synapses	2014
A loss of hippocampal perineuronal nets produces deficits in dopamine system function: relevance to the positive symptoms of schizophrenia. Translational psychiatry, 2013, Jan-15, Volume: 3 Topics: Amphetamine; Analysis of Variance; Animals; Chondroitin ABC Lyase; Chondroitin Sulfate Proteoglycans; Disease Models, Animal; Dopamine; Hippocampus; Immunohistochemistry; Interneurons; Male; Methylazoxymethanol Acetate; Parvalbumins; Rats; Rats, Sprague-Dawley; Schizophrenia	2013
Heterotopic neurons with altered inhibitory synaptic function in an animal model of malformation-associated epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Sep-01, Volume: 22, Issue:17 Topics: Animals; Carrier Proteins; Choristoma; Disease Models, Animal; Epilepsy; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Membrane Proteins; Membrane Transport Proteins; Methylazoxymethanol Acetate; Nervous System Malformations; Neural Inhibition; Neurons; Organic Anion Transporters; Patch-Clamp Techniques; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Synapses	2002
Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia. Epilepsy research, 2002, Volume: 50, Issue:3 Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Disease Models, Animal; Electroencephalography; Epilepsy; Ethosuximide; Female; Hippocampus; In Vitro Techniques; Lamotrigine; Methylazoxymethanol Acetate; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazines; Valproic Acid	2002
An examination of calcium current function on heterotopic neurons in hippocampal slices from rats exposed to methylazoxymethanol. Epilepsia, 2003, Volume: 44, Issue:3 Topics: Animals; Calcium; Calcium Channels; Choristoma; Disease Models, Animal; Electrophysiology; Epilepsy; Female; Hippocampus; Humans; In Vitro Techniques; Methylazoxymethanol Acetate; Nervous System Malformations; Neurons; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Teratogens	2003
Neurogenesis in cerebral heterotopia induced in rats by prenatal methylazoxymethanol treatment. Cerebral cortex (New York, N.Y. : 1991), 2003, Volume: 13, Issue:7 Topics: Animals; Brain Diseases; Bromodeoxyuridine; Cerebral Cortex; Choristoma; Disease Models, Animal; Female; Methylazoxymethanol Acetate; Microscopy, Confocal; Morphogenesis; Neurons; Phenotype; Pregnancy; Rats; Rats, Sprague-Dawley	2003
The NMDA receptor complex is altered in an animal model of human cerebral heterotopia. Journal of neuropathology and experimental neurology, 2003, Volume: 62, Issue:6 Topics: Animals; Animals, Newborn; Autoradiography; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Membrane; Cerebral Cortex; Choristoma; Cloning, Molecular; Disease Models, Animal; Disks Large Homolog 4 Protein; Female; Hippocampus; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Matched-Pair Analysis; Membrane Proteins; Methylazoxymethanol Acetate; Microscopy, Confocal; Nerve Tissue Proteins; Peptide Fragments; Phosphorylation; Pregnancy; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Subcellular Fractions	2003
The prenatal methylazoxymethanol acetate treatment: a neurodevelopmental animal model for schizophrenia? Behavioural brain research, 2004, Mar-02, Volume: 149, Issue:2 Topics: Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Body Weight; Brain; Cognition; Disease Models, Animal; Dose-Response Relationship, Radiation; Embryo, Mammalian; Emotions; Female; Inhibition, Psychological; Male; Methylazoxymethanol Acetate; Motor Activity; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Protein Synthesis Inhibitors; Rats; Reflex, Startle; Schizophrenia; Schizophrenic Psychology; Sex Factors	2004
Excitability of CA1 neurons in the model of malformation-associated epilepsy. Neuroreport, 2004, Jul-19, Volume: 15, Issue:10 Topics: Animals; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Epilepsy; Evoked Potentials; Female; GABA Antagonists; Hippocampus; Male; Methylazoxymethanol Acetate; Neurons; Potassium Acetate; Pregnancy; Rats; Rats, Sprague-Dawley	2004
Working memory deficits in adult rats after prenatal disruption of neurogenesis. Behavioural pharmacology, 2004, Volume: 15, Issue:4 Topics: Abnormalities, Drug-Induced; Animals; Disease Models, Animal; Drug Administration Schedule; Female; Hippocampus; Male; Maze Learning; Memory Disorders; Methylazoxymethanol Acetate; Organ Size; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Time Factors	2004
Refractory atypical absence seizures in rat: a two hit model. Epilepsy research, 2004, Volume: 62, Issue:1 Topics: Animals; Anticholesteremic Agents; Brain; Disease Models, Animal; Drug Resistance; Electroencephalography; Epilepsy, Absence; Female; Methylazoxymethanol Acetate; Pregnancy; Prenatal Exposure Delayed Effects; Protein Synthesis Inhibitors; Rats; Rats, Long-Evans; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride	2004
Cognitive deficits caused by late gestational disruption of neurogenesis in rats: a preclinical model of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:2 Topics: Animals; Association Learning; Cognition Disorders; Conditioning, Operant; Disease Models, Animal; Exploratory Behavior; Female; Maze Learning; Methylazoxymethanol Acetate; Nervous System; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Performance; Rats; Rats, Wistar; Recognition, Psychology; Reversal Learning; Schizophrenia; Swimming; Teratogens	2005
A volumetric screening procedure for the Göttingen minipig brain. Experimental brain research, 2005, Volume: 162, Issue:4 Topics: Algorithms; Anatomy, Cross-Sectional; Animals; Brain; Cell Count; Disease Models, Animal; Female; Methylazoxymethanol Acetate; Nervous System Malformations; Pilot Projects; Pregnancy; Prenatal Exposure Delayed Effects; Swine; Swine, Miniature; Teratogens	2005
Prolonged NMDA-mediated responses, altered ifenprodil sensitivity, and epileptiform-like events in the malformed hippocampus of methylazoxymethanol exposed rats. Journal of neurophysiology, 2005, Volume: 94, Issue:1 Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Methylazoxymethanol Acetate; N-Methylaspartate; Patch-Clamp Techniques; Piperidines; Rats	2005
Endogenous neuregulin restores radial glia in a (ferret) model of cortical dysplasia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Sep-14, Volume: 25, Issue:37 Topics: Animals; Animals, Newborn; Cerebral Cortex; Disease Models, Animal; Female; Ferrets; In Vitro Techniques; Methylazoxymethanol Acetate; Neuregulins; Neuroglia; Pregnancy; Prenatal Exposure Delayed Effects; Teratogens	2005
Decrease in parvalbumin-expressing neurons in the hippocampus and increased phencyclidine-induced locomotor activity in the rat methylazoxymethanol (MAM) model of schizophrenia. The European journal of neuroscience, 2006, Volume: 23, Issue:1 Topics: Analysis of Variance; Animals; Behavior, Animal; Cell Count; Disease Models, Animal; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Gene Expression; Hippocampus; Immunohistochemistry; Methylazoxymethanol Acetate; Motor Activity; Neurons; Parvalbumins; Phencyclidine; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Schizophrenia; Time Factors	2006
Embryonic and early postnatal abnormalities contributing to the development of hippocampal malformations in a rodent model of dysplasia. The Journal of comparative neurology, 2006, Mar-01, Volume: 495, Issue:1 Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Movement; Cell Proliferation; Cerebral Cortex; Choristoma; Disease Models, Animal; Epilepsy; Female; Hippocampus; Methylazoxymethanol Acetate; Nervous System Malformations; Neuroglia; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Stem Cells; Teratogens	2006
A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: implications for the neuropathology of schizophrenia. Biological psychiatry, 2006, Aug-01, Volume: 60, Issue:3 Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Cognition Disorders; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Gait Disorders, Neurologic; Methylazoxymethanol Acetate; Neurons; Neurotoxins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; Schizophrenia	2006
Stromal-derived factor-1 (CXCL12) regulates laminar position of Cajal-Retzius cells in normal and dysplastic brains. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-13, Volume: 26, Issue:37 Topics: Animals; Cell Differentiation; Cell Movement; Cerebral Cortex; Chemokine CXCL12; Chemokines, CXC; Disease Models, Animal; Methylazoxymethanol Acetate; Nervous System Malformations; Neurons; Rats; Rats, Sprague-Dawley; Receptors, CXCR4; Stem Cells; Teratogens	2006
Peri-pubertal maturation after developmental disturbance: a model for psychosis onset in the rat. Neuroscience, 2006, Dec-01, Volume: 143, Issue:2 Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Brain; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Inhibition, Psychological; Interpersonal Relations; Maze Learning; Methylazoxymethanol Acetate; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Psychotic Disorders; Rats; Recognition, Psychology; Reflex, Startle; Time Factors	2006
Determinants of drug brain uptake in a rat model of seizure-associated malformations of cortical development. Neurobiology of disease, 2006, Volume: 24, Issue:3 Topics: Animals; Anticonvulsants; Astrocytes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Capillary Permeability; Choristoma; Disease Models, Animal; Drug Resistance; Endothelial Cells; Epilepsy; Female; Hippocampus; Male; Matched-Pair Analysis; Methylazoxymethanol Acetate; Ondansetron; Pregnancy; Rats; RNA, Messenger; Seizures; Serum Albumin	2006
Gestational methylazoxymethanol acetate treatment impairs select cognitive functions: parallels to schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2 Topics: Animals; Atrophy; Brain; Brain Damage, Chronic; Cognition Disorders; Discrimination Learning; Disease Models, Animal; Female; Learning Disabilities; Male; Methylazoxymethanol Acetate; Neuropsychological Tests; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Performance; Rats; Reinforcement, Psychology; Schizophrenia; Teratogens	2007
Altered glutamate receptor - transporter expression and spontaneous seizures in rats exposed to methylazoxymethanol in utero. Epilepsia, 2007, Volume: 48, Issue:1 Topics: Amino Acid Transport System X-AG; Amygdala; Animals; Cerebral Cortex; Choristoma; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Female; Hippocampus; Immunohistochemistry; Maternal-Fetal Exchange; Methylazoxymethanol Acetate; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Seizures; Teratogens; Vesicular Glutamate Transport Protein 2	2007
Alterations in prefrontal glutamatergic and noradrenergic systems following MK-801 administration in rats prenatally exposed to methylazoxymethanol at gestational day 17. Psychopharmacology, 2007, Volume: 192, Issue:3 Topics: Animals; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Male; Methylazoxymethanol Acetate; Microdialysis; Motor Activity; Norepinephrine; Nucleus Accumbens; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2007
Early cerebrovascular and parenchymal events following prenatal exposure to the putative neurotoxin methylazoxymethanol. Neurobiology of disease, 2007, Volume: 26, Issue:2 Topics: Abnormalities, Drug-Induced; Animals; Aquaporin 1; Brain; Cerebral Arteries; Cerebral Cortex; Disease Models, Animal; Female; Methylazoxymethanol Acetate; Neovascularization, Physiologic; Nervous System Malformations; Neurotoxins; Pokeweed Mitogens; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Teratogens; Vascular Endothelial Growth Factor A	2007
Wide spectrum modulation by KP-544 in models relevant for neuronal survival. Neuroreport, 2007, Apr-16, Volume: 18, Issue:6 Topics: Animals; Astrocytes; Cell Death; Cell Survival; Cerebellum; Cyclohexanols; Disease Models, Animal; Drug Synergism; Female; Male; Methylazoxymethanol Acetate; Nerve Growth Factor; Neurites; Neurons; Neuroprotective Agents; Neurotoxins; PC12 Cells; Pregnancy; Pyrimidines; Rats; Schizophrenia	2007
Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Oct-17, Volume: 27, Issue:42 Topics: Action Potentials; Animals; Disease Models, Animal; Dopamine; Hippocampus; Male; Methylazoxymethanol Acetate; Rats; Rats, Sprague-Dawley; Schizophrenia	2007
Migration of transplanted neural progenitor cells in a ferret model of cortical dysplasia. Experimental neurology, 2008, Volume: 210, Issue:1 Topics: Amino Acids; Analysis of Variance; Animals; Animals, Newborn; Cell Culture Techniques; Cell Movement; Cell Proliferation; Disease Models, Animal; Embryo, Mammalian; Female; Ferrets; Malformations of Cortical Development; Methylazoxymethanol Acetate; Mice; Nerve Tissue Proteins; Neurons; Organ Culture Techniques; Pregnancy; Prenatal Exposure Delayed Effects; Stem Cell Transplantation; Stem Cells	2008
Pervasive hyperactivity and long-term learning impairments in rats with induced micrencephaly from prenatal exposure to methylazoxymethanol. Brain research, 1984, Volume: 317, Issue:1 Topics: Animals; Azo Compounds; Body Weight; Brain; Disease Models, Animal; Female; Humans; Hyperkinesis; Intellectual Disability; Learning Disabilities; Male; Methylazoxymethanol Acetate; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Spatial Behavior	1984
Seizure susceptibility in immature rats with micrencephaly induced by prenatal exposure to methylazoxymethanol acetate. Pharmacological research, 1995, Volume: 31, Issue:2 Topics: Age Factors; Animals; Bicuculline; Body Weight; Brain; Disease Models, Animal; Female; Humans; Infant, Newborn; Kainic Acid; Maternal-Fetal Exchange; Methylazoxymethanol Acetate; Pregnancy; Rats; Rats, Wistar; Seizures	1995
Colonoscopic colostomy model in rats for colon tumorigenesis studies. Carcinogenesis, 1994, Volume: 15, Issue:8 Topics: 1,2-Dimethylhydrazine; Animals; Colonic Neoplasms; Colonoscopy; Colostomy; Dimethylhydrazines; Disease Models, Animal; Male; Methylazoxymethanol Acetate; Rats; Rats, Inbred F344	1994
The effect of dietary selenium deficiency on acute colorectal mucosal nucleotoxicity induced by several carcinogens in the rodent. American journal of surgery, 1996, Volume: 172, Issue:1 Topics: Animals; Carcinogenicity Tests; Carcinogens; Colorectal Neoplasms; Deficiency Diseases; Disease Models, Animal; Intestinal Mucosa; Male; Methylazoxymethanol Acetate; Mitosis; Monomethylhydrazine; Rats; Rats, Sprague-Dawley; Selenium; Tumor Stem Cell Assay	1996
Absence of p53 gene mutations in rat colon carcinomas induced through the synergistic interaction between methylazoxymethanol and X-irradiation. Cancer letters, 1997, Feb-26, Volume: 113, Issue:1-2 Topics: Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Disease Models, Animal; Immunohistochemistry; Male; Methylazoxymethanol Acetate; Neoplasms, Radiation-Induced; Point Mutation; Rats; Tumor Suppressor Protein p53; Whole-Body Irradiation	1997
No involvement of APC gene mutations in ulcerative colitis-associated rat colon carcinogenesis induced by 1-hydroxyanthraquinone and methylazoxymethanol acetate. Molecular carcinogenesis, 1997, Volume: 20, Issue:4 Topics: Animals; Anthraquinones; Base Sequence; Carcinogens; Colitis, Ulcerative; Colonic Neoplasms; Disease Models, Animal; DNA Primers; Genes, APC; Genes, ras; Humans; Male; Methylazoxymethanol Acetate; Mutagenesis; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Rats; Rats, Inbred F344	1997
Transplacentally induced neuronal migration disorders: an animal model for the study of the epilepsies. Journal of neuroscience research, 1998, Feb-15, Volume: 51, Issue:4 Topics: Animals; Behavior, Animal; Body Weight; Brain; Brain Mapping; Cell Movement; Disease Models, Animal; Electroencephalography; Epilepsy; Female; Gestational Age; Hippocampus; Litter Size; Maternal-Fetal Exchange; Methylazoxymethanol Acetate; Neurons; Organ Size; Pregnancy; Rats; Rats, Sprague-Dawley; Seizures	1998
Methylazoxymethanol acetate-induced abnormalities in the entorhinal cortex of the rat; parallels with morphological findings in schizophrenia. Brain research, 1998, Apr-13, Volume: 789, Issue:2 Topics: Animals; Disease Models, Animal; Entorhinal Cortex; Female; Frontal Lobe; Gestational Age; Gyrus Cinguli; Hippocampus; Immunohistochemistry; Isoenzymes; Male; Methylazoxymethanol Acetate; Occipital Lobe; Pregnancy; Prenatal Exposure Delayed Effects; Protein Kinase C; Rats; Rats, Wistar; Schizophrenia	1998
Altered connections between neocortical and heterotopic areas in methylazoxymethanol-treated rat. Epilepsy research, 1998, Volume: 32, Issue:1-2 Topics: Animals; Axonal Transport; Brain; Brain Diseases; Choristoma; Disease Models, Animal; Female; Functional Laterality; Gestational Age; Humans; Methylazoxymethanol Acetate; Neocortex; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Teratogens	1998
Prenatal methylazoxymethanol acetate alters behavior and brain NGF levels in young rats: a possible correlation with the development of schizophrenia-like deficits. Neuropharmacology, 1999, Volume: 38, Issue:6 Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Brain; Disease Models, Animal; Exploratory Behavior; Female; Methylazoxymethanol Acetate; Nerve Growth Factors; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Schizophrenia; Social Behavior; Substance P	1999
Hippocampal heterotopia lack functional Kv4.2 potassium channels in the methylazoxymethanol model of cortical malformations and epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Sep-01, Volume: 21, Issue:17 Topics: 4-Aminopyridine; Action Potentials; Animals; Cerebral Cortex; Choristoma; Delayed Rectifier Potassium Channels; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Female; Hippocampus; Immunohistochemistry; In Situ Hybridization; In Vitro Techniques; Methylazoxymethanol Acetate; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Pregnancy; Prenatal Exposure Delayed Effects; Pyramidal Cells; Rats; RNA, Messenger; Shab Potassium Channels; Shal Potassium Channels; Somatosensory Cortex; Tetraethylammonium	2001
Persistent innervation of the rat neocortex by basal forebrain cholinergic neurons despite the massive reduction of cortical target neurons. II. Neurochemical analysis. Experimental neurology, 1992, Volume: 117, Issue:2 Topics: Acetylcholinesterase; Aging; Alzheimer Disease; Animals; Brain; Cerebral Cortex; Choline O-Acetyltransferase; Disease Models, Animal; Female; Fetus; Gestational Age; Methylazoxymethanol Acetate; Neurons; Pregnancy; Prosencephalon; Rats; Rats, Inbred Strains; Somatostatin	1992
Persistent innervation of the rat neocortex by basal forebrain cholinergic neurons despite the massive reduction of cortical target neurons. I. Morphometric analysis. Experimental neurology, 1992, Volume: 117, Issue:2 Topics: Acetylcholine; Aging; Alzheimer Disease; Animals; Cerebral Cortex; Disease Models, Animal; Female; Fetus; Gestational Age; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Male; Methylazoxymethanol Acetate; Neurons; Pregnancy; Prosencephalon; Rats; Rats, Inbred Strains	1992
Behavioral deficits in rats with minimal cortical hypoplasia induced by methylazoxymethanol acetate. Pediatrics, 1990, Volume: 85, Issue:3 Pt 2 Topics: Animals; Attention Deficit Disorder with Hyperactivity; Azo Compounds; Brain Chemistry; Cerebral Cortex; Disease Models, Animal; Female; Learning Disabilities; Methylazoxymethanol Acetate; Microcephaly; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains	1990
Differential susceptibility of a fish, tilapia Oreochromis mossambicus (Teleostei, Cichlidae) to hepatocarcinogenesis by diethylnitrosamine and methylazoxymethanol acetate. Carcinogenesis, 1989, Volume: 10, Issue:3 Topics: Animals; Azo Compounds; Cells, Cultured; Diethylnitrosamine; Disease Models, Animal; Female; Fish Diseases; gamma-Glutamyltransferase; Liver Neoplasms, Experimental; Male; Methylazoxymethanol Acetate; Perciformes; Tyrosine Transaminase	1989
Prenatal methylazoxymethanol treatment potentiates d-amphetamine- and methylphenidate-induced motor activity in male and female rats. Pharmacology & toxicology, 1988, Volume: 63, Issue:4 Topics: Animals; Attention Deficit Disorder with Hyperactivity; Azo Compounds; Dextroamphetamine; Disease Models, Animal; Drug Synergism; Female; Fetus; Male; Methylazoxymethanol Acetate; Methylphenidate; Motor Activity; Rats; Receptors, Dopamine	1988
Intraocular neoplasms induced by methylazoxymethanol acetate in Japanese medaka (Oryzias latipes). Journal of the National Cancer Institute, 1986, Volume: 76, Issue:3 Topics: Age Factors; Animals; Azo Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Eye Neoplasms; Fishes; Methylazoxymethanol Acetate; Neuroectodermal Tumors, Primitive, Peripheral; Retinoblastoma	1986
Microencephalic rats as a model for cognitive disorders. Clinical neuropharmacology, 1986, Volume: 9 Suppl 3 Topics: Animals; Azo Compounds; Cognition Disorders; Disease Models, Animal; Female; Gestational Age; Learning Disabilities; Methylazoxymethanol Acetate; Microcephaly; Motor Activity; Pregnancy; Rats; Reflex	1986