Page last updated: 2024-10-31

methyl salicylate and Conjunctivitis, Allergic

methyl salicylate has been researched along with Conjunctivitis, Allergic in 26 studies

methyl salicylate: used in over-the-counter liniments, ointments, lotions for relief of musculoskeletal aches and pains; has hemolytic effect on human & sheep erythrocytes; RN given refers to parent cpd; structure in Merck Index, 9th ed, #5990
methyl salicylate : A benzoate ester that is the methyl ester of salicylic acid.

Conjunctivitis, Allergic: Conjunctivitis due to hypersensitivity to various allergens.

Research Excerpts

ExcerptRelevanceReference
" This study investigated the clinical efficacy, safety and dose-response relationship of SLIT in children suffering from rhinoconjunctivitis with/without asthma."2.72Clinical efficacy and safety of sublingual immunotherapy with tree pollen extract in children. ( Jacobsen, L; Koivikko, A; Ljørring, C; Savolainen, J; Valovirta, E, 2006)
"All subjects had moderate to severe hay fever symptoms, but at inclusion none reported asthma with need of daily treatment."2.70Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study). ( Dreborg, S; Ferdousi, HA; Halken, S; Høst, A; Jacobsen, L; Koivikko, A; Koller, DY; Möller, C; Niggemann, B; Norberg, LA; Urbanek, R; Valovirta, E; Wahn, U, 2002)
"High-dose, subcutaneous IT is efficacious and safe in patients with severe birch pollen rhinoconjunctivitis and asthma."2.70The safety and efficacy of subcutaneous birch pollen immunotherapy - a one-year, randomised, double-blind, placebo-controlled study. ( Bødtger, U; Jacobi, HH; Malling, HJ; Poulsen, LK, 2002)
"Five patients with seasonal allergic conjunctivitis (SAC) and five healthy subjects were included for validation purposes."1.38Conjunctival provocation with airborne allergen in patients with atopic keratoconjunctivitis. ( Gafvelin, G; Montan, PG; Nivenius, E; Van der Ploeg, I; Van Hage, M, 2012)
" High dosages of allergen were more effective while mode of dosing up did not seem to matter."1.35CD-sens: a biological measure of immunological changes stimulated by ASIT. ( Cardell, LO; Johansson, SG; Nopp, A; Oman, H, 2009)
"An episode of treated allergic rhinitis, rhinosinusitus, or conjunctivitis (ARC) was defined as the association of an oral antihistamine and a local antiallergic drug on the same prescription."1.34Short-term effect of pollen exposure on antiallergic drug consumption. ( Caillaud, D; Delmas, MC; Fuhrman, C; Lecadet, J; Sarter, H; Thibaudon, M; Zeghnoun, A, 2007)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's16 (61.54)29.6817
2010's9 (34.62)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Ishida, W1
Kishimoto, T1
Takaiwa, F1
Fukuda, K1
Buczyłko, K1
van der Werf, JF1
Boot, D1
van Ree, R1
Ellis, AK1
Tenn, MW1
Steacy, LM1
Adams, DE1
Day, AG1
Walker, TJ1
Nolte, H1
Couroux, P1
Ipsen, H1
Stage, BS2
Damkjaer, JT1
Steffensen, MA1
Salapatek, AM1
Lund, K1
Würtzen, PA1
Pfaar, O1
Bachert, C1
Kuna, P2
Panzner, P2
Džupinová, M1
Klimek, L1
van Nimwegen, MJ1
Boot, JD1
Yu, D1
Opstelten, DJE1
de Kam, PJ1
Biedermann, T1
Valovirta, E3
Andersson, M1
de Blay, F1
Thrane, D1
Jacobsen, SH1
Winther, L1
Caillaud, D2
Martin, S1
Segala, C1
Besancenot, JP1
Clot, B1
Thibaudon, M2
Moingeon, P1
Floch, VB1
Airouche, S1
Baron-Bodo, V1
Nony, E1
Mascarell, L1
Tagawa, Y1
Namba, K1
Nakazono, Y1
Iwata, D1
Ishida, S1
Pauli, G2
Larsen, TH1
Rak, S2
Horak, F1
Pastorello, E1
Valenta, R3
Purohit, A1
Arvidsson, M1
Kavina, A1
Schroeder, JW1
Mothes, N1
Spitzauer, S1
Montagut, A1
Galvain, S1
Melac, M1
André, C1
Poulsen, LK2
Malling, HJ2
Nopp, A1
Cardell, LO1
Johansson, SG1
Oman, H1
Nivenius, E1
Van der Ploeg, I1
Gafvelin, G1
Van Hage, M1
Montan, PG1
Movérare, R1
Westritschnig, K1
Svensson, M1
Hayek, B1
Bende, M1
Sorva, R1
Haahtela, T2
Elfman, L1
Laaidi, M1
Laaidi, K1
Rigollet, S1
Jahnz-Rózyk, K1
Targowski, T1
Głodzinska-Wyszogrodzka, E1
Płusa, T1
Roever, AC1
Heine, G1
Zuberbier, T1
Worm, M1
Helintö, M1
Renkonen, R1
Tervo, T1
Vesaluoma, M1
Saaren-Seppälä, H1
Kirveskari, J1
Heinrich, C1
Scheynius, A1
Kihlström, A1
Hedlin, G1
Pershagen, G1
Troye-Blomberg, M1
Härfast, B1
Lilja, G1
Jacobsen, L2
Ljørring, C1
Koivikko, A2
Savolainen, J1
Ridolo, E1
Albertini, R1
Giordano, D1
Soliani, L1
Usberti, I1
Dall'Aglio, PP1
Fuhrman, C1
Sarter, H1
Delmas, MC1
Zeghnoun, A1
Lecadet, J1
Jenmalm, MC1
Van Snick, J1
Cormont, F1
Salman, B1
Riediker, M1
Monn, C1
Koller, T1
Stahel, WA1
Wüthrich, B1
Möller, C1
Dreborg, S1
Ferdousi, HA1
Halken, S1
Høst, A1
Koller, DY1
Niggemann, B1
Norberg, LA1
Urbanek, R1
Wahn, U1
Bødtger, U1
Jacobi, HH1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Impact of Grass SLIT Treatment on Birch Pollen Induced Allergic Rhinitis - a Pilot Evaluation[NCT02394600]Phase 493 participants (Actual)Interventional2015-04-30Completed
A Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Assess the Clinical Efficacy and Safety of SUBLIVAC FIX Birch Immunotherapy in Patients Suffering From Allergic Rhinitis/Rhinoconjunctivitis Caused by Birch Pollen.[NCT02231307]Phase 3406 participants (Actual)Interventional2014-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Total Nasal Symptom Score (TNSS) From Baseline to Post-treatment.

"To determine the effect of 4 months of treatment with Grastek® on the symptoms of birch pollen induced AR in participants with both timothy grass pollen-induced and birch pollen-induced allergen rhinitis (AR)~TNSS is comprised of the sum of 4 symptoms: runny nose, itchy nose sneezing and nasal congestion. Each of these symptoms are evaluated based on a 4 point Likert scale from 0-3. 0 = no symptoms, 1 = mild symptoms, 2 = moderate symptoms and 3 = severe symptoms. TNSS can therefore have a range from 0 to 12." (NCT02394600)
Timeframe: 4 months

InterventionScores on a scale (Mean)
Grastek2.3
Placebo2.2

Reviews

1 review available for methyl salicylate and Conjunctivitis, Allergic

ArticleYear
Allergen immunotherapy for birch pollen-allergic patients: recent advances.
    Immunotherapy, 2016, Volume: 8, Issue:5

    Topics: Animals; Antigens, Plant; Betula; Clinical Trials as Topic; Conjunctivitis, Allergic; Desensitizatio

2016

Trials

11 trials available for methyl salicylate and Conjunctivitis, Allergic

ArticleYear
Accelerated Up-Dosing of Subcutaneous Immunotherapy with a Registered Allergoid Birch Pollen Preparation.
    International archives of allergy and immunology, 2017, Volume: 172, Issue:3

    Topics: Administration, Cutaneous; Adolescent; Adult; Allergens; Antigens, Plant; Asthma; Betula; Child; Con

2017
Lack of effect of Timothy grass pollen sublingual immunotherapy tablet on birch pollen-induced allergic rhinoconjunctivitis in an environmental exposure unit.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2018, Volume: 120, Issue:5

    Topics: Administration, Sublingual; Adolescent; Adult; Aged; Allergens; Betula; Biomarkers; Conjunctivitis,

2018
A birch sublingual allergy immunotherapy tablet reduces rhinoconjunctivitis symptoms when exposed to birch and oak and induces IgG
    Allergy, 2019, Volume: 74, Issue:2

    Topics: Adolescent; Adult; Aged; Betula; Conjunctivitis, Allergic; Female; Humans; Immunoglobulin E; Immunog

2019
Sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma.
    The Journal of allergy and clinical immunology, 2019, Volume: 143, Issue:3

    Topics: Adolescent; Adult; Aged; Allergens; Antigens, Plant; Asthma; Betula; Conjunctivitis, Allergic; Doubl

2019
The SQ tree SLIT-tablet is highly effective and well tolerated: Results from a randomized, double-blind, placebo-controlled phase III trial.
    The Journal of allergy and clinical immunology, 2019, Volume: 143, Issue:3

    Topics: Adolescent; Adult; Aged; Allergens; Betula; Child; Conjunctivitis, Allergic; Double-Blind Method; Hu

2019
Evaluating the efficacy of epinastine ophthalmic solution using a conjunctivitis allergen challenge model in patients with birch pollen allergic conjunctivitis.
    Allergology international : official journal of the Japanese Society of Allergology, 2017, Volume: 66, Issue:2

    Topics: Adult; Allergens; Anti-Allergic Agents; Betula; Biomarkers; Conjunctivitis, Allergic; Dibenzazepines

2017
Efficacy of recombinant birch pollen vaccine for the treatment of birch-allergic rhinoconjunctivitis.
    The Journal of allergy and clinical immunology, 2008, Volume: 122, Issue:5

    Topics: Adult; Allergens; Anti-Allergic Agents; Betula; Conjunctivitis, Allergic; Desensitization, Immunolog

2008
Comparison of nasal immunohistology in patients with seasonal rhinoconjunctivitis treated with topical steroids or specific allergen immunotherapy.
    Allergy, 2005, Volume: 60, Issue:5

    Topics: Administration, Topical; Adult; Antigens, CD1; Betula; Biopsy; Conjunctivitis, Allergic; Desensitiza

2005
Clinical efficacy and safety of sublingual immunotherapy with tree pollen extract in children.
    Allergy, 2006, Volume: 61, Issue:10

    Topics: Administration, Sublingual; Adolescent; Allergens; Alnus; Betula; Case-Control Studies; Child; Child

2006
Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study).
    The Journal of allergy and clinical immunology, 2002, Volume: 109, Issue:2

    Topics: Adolescent; Asthma; Betula; Bronchial Provocation Tests; Child; Conjunctivitis, Allergic; Desensitiz

2002
The safety and efficacy of subcutaneous birch pollen immunotherapy - a one-year, randomised, double-blind, placebo-controlled study.
    Allergy, 2002, Volume: 57, Issue:4

    Topics: Adult; Allergens; Antibody Specificity; Betula; Conjunctivitis, Allergic; Desensitization, Immunolog

2002

Other Studies

14 other studies available for methyl salicylate and Conjunctivitis, Allergic

ArticleYear
Prophylactic and Therapeutic Effects of Oral Immunotherapy on Birch Pollen-Induced Allergic Conjunctivitis in Mice with a Rice-Based Edible Vaccine Expressing a Hypoallergenic Birch Pollen Allergen.
    Cells, 2021, 11-30, Volume: 10, Issue:12

    Topics: Administration, Oral; Allergens; Animals; Betula; Conjunctivitis, Allergic; Desensitization, Immunol

2021
Effects of airborne birch pollen levels on clinical symptoms of seasonal allergic rhinoconjunctivitis.
    International archives of allergy and immunology, 2014, Volume: 163, Issue:1

    Topics: Adult; Air Pollutants; Allergens; Betula; Conjunctivitis, Allergic; Female; Humans; Male; Middle Age

2014
CD-sens: a biological measure of immunological changes stimulated by ASIT.
    Allergy, 2009, Volume: 64, Issue:5

    Topics: Allergens; Basophils; Betula; Conjunctivitis, Allergic; Desensitization, Immunologic; Humans; Immuno

2009
Conjunctival provocation with airborne allergen in patients with atopic keratoconjunctivitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2012, Volume: 42, Issue:1

    Topics: Adult; Aged; Air Pollution; Allergens; Betula; Conjunctiva; Conjunctivitis, Allergic; Cytokines; Fem

2012
Different IgE reactivity profiles in birch pollen-sensitive patients from six European populations revealed by recombinant allergens: an imprint of local sensitization.
    International archives of allergy and immunology, 2002, Volume: 128, Issue:4

    Topics: Adolescent; Adult; Aged; Allergens; Antibody Specificity; Antigens, Plant; Asthma; Betula; Calcium-B

2002
[Pollen counts and allergies in Burgundy: profile and perspectives].
    European annals of allergy and clinical immunology, 2003, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Air; Allergens; Asthma; Betula; Child; Conjunctivitis, Allergic; Environmental Mo

2003
Cc-chemokine eotaxin as a marker of efficacy of specific immunotherapy in patients with intermittent IgE-mediated allergic rhinoconjunctivitis.
    Allergy, 2003, Volume: 58, Issue:7

    Topics: Administration, Inhalation; Adult; Allergens; Anti-Allergic Agents; Betula; Biomarkers; Chemokines,

2003
Allergen-mediated modulation of CD23 expression is interferon-gamma and interleukin-10 dependent in allergic and non-allergic individuals.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2003, Volume: 33, Issue:11

    Topics: Adult; Allergens; B-Lymphocytes; Betula; Cells, Cultured; Conjunctivitis, Allergic; Down-Regulation;

2003
Direct in vivo monitoring of acute allergic reactions in human conjunctiva.
    Journal of immunology (Baltimore, Md. : 1950), 2004, Mar-01, Volume: 172, Issue:5

    Topics: Acute Disease; Adult; Allergens; Betula; Cell Adhesion Molecules; Chemotaxis, Leukocyte; Conjunctiva

2004
Immunoglobulin G4-antibodies to rBet v 1 and risk of sensitization and atopic disease in the child.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:12

    Topics: Air Pollutants; Allergens; Betula; Chi-Square Distribution; Child, Preschool; Conjunctivitis, Allerg

2005
Airborne pollen concentrations and the incidence of allergic asthma and rhinoconjunctivitis in northern Italy from 1992 to 2003.
    International archives of allergy and immunology, 2007, Volume: 142, Issue:2

    Topics: Adult; Ambrosia; Animals; Animals, Domestic; Asthma; Betula; Conjunctivitis, Allergic; Female; Human

2007
Short-term effect of pollen exposure on antiallergic drug consumption.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2007, Volume: 99, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Anti-Allergic Agents; Antigens, Plant; Betula; Child; Child, P

2007
Allergen-induced Th1 and Th2 cytokine secretion in relation to specific allergen sensitization and atopic symptoms in children.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2001, Volume: 31, Issue:10

    Topics: Allergens; Animals; Antibodies; Asthma; Betula; Cats; Child; Child Welfare; Conjunctivitis, Allergic

2001
Air pollutants enhance rhinoconjunctivitis symptoms in pollen-allergic individuals.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2001, Volume: 87, Issue:4

    Topics: Adult; Air Pollutants; Allergens; Betula; Conjunctivitis, Allergic; Environmental Exposure; Female;

2001