methyl-retinoate and Vitamin-A-Deficiency

methyl-retinoate has been researched along with Vitamin-A-Deficiency* in 1 studies

Other Studies

1 other study(ies) available for methyl-retinoate and Vitamin-A-Deficiency

Article	Year
Dihydroretinoic acids and their derivatives. Synthesis and biological activity. Journal of medicinal chemistry, 1977, Volume: 20, Issue:7 The syntheses of the ring and four side-chain dihydroretinoic acids and/or their esters, 3-7, are described. The syntheses of several other retinoids containing a substituted aromatic ring are also included. The biological activity of the compounds was evaluated in vivo in a chemically induced mouse skin papilloma test and in vitro in two vitamin A deficient assays. The activity observed for 1a, 1c, and 2a in the former test was partially retained in the dihydro derivatives 4b, 4c, and 6b. Similar results were found in the in vitro assays. Topics: Animals; Cells, Cultured; Cricetinae; Female; Mice; Neoplasms, Experimental; Organ Culture Techniques; Papilloma; RNA; Skin; Skin Neoplasms; Tretinoin; Vitamin A; Vitamin A Deficiency	1977

Article

Year

Dihydroretinoic acids and their derivatives. Synthesis and biological activity.

Journal of medicinal chemistry, 1977, Volume: 20, Issue:7

The syntheses of the ring and four side-chain dihydroretinoic acids and/or their esters, 3-7, are described. The syntheses of several other retinoids containing a substituted aromatic ring are also included. The biological activity of the compounds was evaluated in vivo in a chemically induced mouse skin papilloma test and in vitro in two vitamin A deficient assays. The activity observed for 1a, 1c, and 2a in the former test was partially retained in the dihydro derivatives 4b, 4c, and 6b. Similar results were found in the in vitro assays.

Topics: Animals; Cells, Cultured; Cricetinae; Female; Mice; Neoplasms, Experimental; Organ Culture Techniques; Papilloma; RNA; Skin; Skin Neoplasms; Tretinoin; Vitamin A; Vitamin A Deficiency

1977