methyl-prednisolonate has been researched along with Edema* in 1 studies
1 other study(ies) available for methyl-prednisolonate and Edema
| Article | Year |
|---|---|
Antiinflammatory activity of two novel derivatives of prednisolone.
The antiinflammatory activity of two new steroids synthesized by modifying the 17 beta-ketol side chain of prednisolone to the glycolate and glyoxylate methyl esters has been investigated in the carrageenin pedal edema test in rats. The two ester derivatives retained anti-inflammatory potency, nearly equivalent to that of the parent compound, when administered subcutaneously at the site of inflammation. However, the glyoxylate ester, when administered by systemic route, showed a weaker suppression of inflammation. The glycolate ester showed a reverse trend in that it was more effective when it was administered by systemic route than when it was applied topically. Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Edema; Injections, Subcutaneous; Male; Prednisolone; Rats | 1980 |