Page last updated: 2024-10-31

methyl parathion and Pregnancy

methyl parathion has been researched along with Pregnancy in 24 studies

Methyl Parathion: The methyl homolog of parathion. An effective, but highly toxic, organothiophosphate insecticide and cholinesterase inhibitor.
parathion-methyl : A C-nitro compound that is 4-nitrophenol substituted by a (dimethoxyphosphorothioyl)oxy group at position 4.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" The dosage of the two pesticides were (0, 1/300, 1/95 and 1/30) LD50, respectively."1.34[Studies on DNA damage of the neuron cell in rat offspring induced by cypermerthrin and methylparathrion during embryo exposure]. ( Liu, P; Wang, F; Wang, J; Wu, X, 2007)
" Pharmacokinetic studies showed that methyl parathion disappeared monoexponentially from plasma and tissues."1.31Placental transfer and pharmacokinetics of a single dermal dose of [14C]methyl parathion in rats. ( Abdel-Rahman, AA; Abou-Donia, MB; Abu-Qare, AW; Kishk, AM, 2000)
" Following application of methyl parathion, peak inhibition of maternal and fetal brain AChE activity occurred at 48 h and 24 h after dosing (17% and 48% of control activity, respectively)."1.31Inhibition of cholinesterase enzymes following a single dermal dose of chlorpyrifos and methyl parathion, alone and in combination, in pregnant rats. ( Abdel-Rahman, A; Abou-Donia, MB; Abu-Qare, AW; Brownie, C; Kishk, AM, 2001)
"The number of chromosome aberrations observed in bone marrow cells and spermatogonia, and the frequency of pre- and postimplantation foetal lethality obtained in a dominant lethal mutation assay, did not conclusively prove that the tested compounds produced a mutagenic effect."1.27Absence of genetic and cytogenetic effects in mice treated by the organophosphorus insecticide parathion, its methyl analogue, and paraoxon. ( Degraeve, N; Moutschen, J, 1984)
" With T alone, rats of the postnatal group were dosed daily with 6 mg/kg for 21 days, while in the perinatal study females received 6 mg/kg daily from Day 7 of pregnancy until parturition."1.26Behavioral effects of methyl parathion and toxaphene exposure in rats. ( Crowder, LA; Lanzaro, GC; Whitson, RS, 1980)
" Prenatal toxic action of the pesticides used today may be detrimental to human and animal health."1.26[Studies on the prenatally toxic effect of parathionemethyl in Wistar rats compared to cyclophosphamide and trypan blue]. ( Fuchs, V; Golbs, S; Kühnert, M; Osswald, F, 1976)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199010 (41.67)18.7374
1990's5 (20.83)18.2507
2000's7 (29.17)29.6817
2010's1 (4.17)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Zhang, J1
Li, Z1
Dai, Y1
Guo, J1
Qi, X1
Liu, P2
Lv, S1
Lu, D1
Liang, W1
Chang, X1
Cao, Y1
Wu, C1
Zhou, Z1
Nair, R1
Singh, VJ1
Salian, SR1
Kalthur, SG1
D'Souza, AS1
Shetty, PK1
Mutalik, S1
Kalthur, G1
Adiga, SK1
McCann, KG1
Moomey, CM1
Runkle, KD1
Hryhorczuk, DO1
Clark, JM1
Barr, DB1
Levario-Carrillo, M1
Olave, ME1
Corral, DC1
Alderete, JG1
Gagioti, SM1
Bevilacqua, E1
Wang, J1
Wu, X1
Wang, F1
Degraeve, N1
Moutschen, J1
Gupta, RC2
Thornburg, JE2
Stedman, DB1
Welsch, F2
Várnagy, L2
Korzenszky, M1
Fáncsi, T1
Crowder, LA1
Lanzaro, GC1
Whitson, RS1
Sortur, SM1
Kaliwal, BB1
Abu-Qare, AW3
Abdel-Rahman, AA1
Kishk, AM2
Abou-Donia, MB3
Abdel-Rahman, A1
Brownie, C1
Howard, MD1
Pope, CN2
Fuchs, V1
Golbs, S1
Kühnert, M1
Osswald, F1
Goncharuk, EI1
Sidorenko, GI1
Golubchikov, MV2
Prokopovich, AS1
Chakraborti, TK1
Chapman, ML1
Farrar, JD1
Arthun, D1
Radulovic, LL1
LaFerla, JJ1
Kulkarni, AP1
Rech, RH1
Lovell, KL1
Déli, E1
Uzokwu, M1
Karash, IuM2
Chizhov, AIa2
Evgen'eva, IA1
Egorova, EB1
Filimonov, VG1

Other Studies

24 other studies available for methyl parathion and Pregnancy

ArticleYear
Urinary para-nitrophenol levels of pregnant women and cognitive and motor function of their children aged 2 years: Evidence from the SMBCS (China).
    Ecotoxicology and environmental safety, 2022, Oct-01, Volume: 244

    Topics: Biomarkers; China; Cognition; Cohort Studies; Female; Gas Chromatography-Mass Spectrometry; Humans;

2022
Methyl parathion inhibits the nuclear maturation, decreases the cytoplasmic quality in oocytes and alters the developmental potential of embryos of Swiss albino mice.
    Toxicology and applied pharmacology, 2014, Sep-15, Volume: 279, Issue:3

    Topics: Animals; Blastocyst; Cell Count; Cell Nucleus; Cytoplasm; Embryonic Development; Female; Fetus; Germ

2014
Chicago area methyl parathion response.
    Environmental health perspectives, 2002, Volume: 110 Suppl 6

    Topics: Adolescent; Adult; Aged; Chicago; Child; Child, Preschool; Environment; Environmental Exposure; Envi

2002
Placental morphology of rats prenatally exposed to methyl parathion.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2004, Volume: 55, Issue:6

    Topics: Administration, Oral; Animals; Body Weight; Diet; Dose-Response Relationship, Drug; Female; Fetal Re

2004
[Studies on DNA damage of the neuron cell in rat offspring induced by cypermerthrin and methylparathrion during embryo exposure].
    Wei sheng yan jiu = Journal of hygiene research, 2007, Volume: 36, Issue:3

    Topics: Animals; Animals, Newborn; Brain; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; Fema

2007
Absence of genetic and cytogenetic effects in mice treated by the organophosphorus insecticide parathion, its methyl analogue, and paraoxon.
    Toxicology, 1984, Volume: 32, Issue:2

    Topics: Animals; Bone Marrow; Chromosome Aberrations; Female; Genes, Dominant; Genes, Lethal; Male; Methyl M

1984
Effect of subchronic administration of methyl parathion on in vivo protein synthesis in pregnant rats and their conceptuses.
    Toxicology and applied pharmacology, 1984, Mar-15, Volume: 72, Issue:3

    Topics: Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Female; Fetus; Maternal-Fetal E

1984
Teratological examination of the insecticide methylparathion (Wofatox 50 EC) on pheasant embryos. 1. Morphological study.
    Veterinary research communications, 1984, Volume: 8, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Bird Diseases; Birds; Female; Methyl

1984
Behavioral effects of methyl parathion and toxaphene exposure in rats.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 1980, Volume: 15, Issue:4

    Topics: Administration, Oral; Age Factors; Animals; Animals, Newborn; Behavior, Animal; Female; Insecticides

1980
Effect of methyl parathion formulation on estrous cycle and reproductive performance in albino rats.
    Indian journal of experimental biology, 1999, Volume: 37, Issue:2

    Topics: Animals; Estrus; Female; Insecticides; Litter Size; Methyl Parathion; Pregnancy; Rats; Rats, Wistar;

1999
Placental transfer and pharmacokinetics of a single dermal dose of [14C]methyl parathion in rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 53, Issue:1

    Topics: Administration, Cutaneous; Animals; Animals, Newborn; Area Under Curve; Chromatography, High Pressur

2000
Urinary excretion of metabolites following a single dermal dose of [14C]methyl parathion in pregnant rats.
    Toxicology, 2000, Sep-07, Volume: 150, Issue:1-3

    Topics: Administration, Cutaneous; Animals; Chromatography, High Pressure Liquid; Female; Insecticides; Meth

2000
Inhibition of cholinesterase enzymes following a single dermal dose of chlorpyrifos and methyl parathion, alone and in combination, in pregnant rats.
    Journal of toxicology and environmental health. Part A, 2001, Jun-08, Volume: 63, Issue:3

    Topics: Acetylcholinesterase; Administration, Cutaneous; Analysis of Variance; Animals; Brain; Butyrylcholin

2001
In vitro effects of chlorpyrifos, parathion, methyl parathion and their oxons on cardiac muscarinic receptor binding in neonatal and adult rats.
    Toxicology, 2002, Jan-15, Volume: 170, Issue:1-2

    Topics: Aging; Animals; Animals, Newborn; Binding, Competitive; Chlorpyrifos; Cholinesterase Inhibitors; Fem

2002
[Studies on the prenatally toxic effect of parathionemethyl in Wistar rats compared to cyclophosphamide and trypan blue].
    Archiv fur experimentelle Veterinarmedizin, 1976, Volume: 30, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Cyclophosphamide; Embryo Implantation; Embryo Loss; Embryo, Ma

1976
[Use of the mother-fetus-newborn infant system for the study of combined effects of pesticides and other chemicals].
    Gigiena i sanitariia, 1990, Issue:6

    Topics: Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Fetus; Hexachlorocyclohexane; I

1990
[Toxicological substantiation of safe use of xenobiotics].
    Gigiena i sanitariia, 1991, Issue:1

    Topics: Animals; Animals, Newborn; Animals, Suckling; Female; Fetal Blood; Hexachlorocyclohexane; Insecticid

1991
Comparison of in vivo cholinesterase inhibition in neonatal and adult rats by three organophosphorothioate insecticides.
    Toxicology, 1991, Volume: 68, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Chlorpyrifos; Cholinesterase Inhibitors; C

1991
Human placental glutathione S-transferase-mediated metabolism of methyl parathion.
    Biochemical pharmacology, 1986, Oct-15, Volume: 35, Issue:20

    Topics: Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Female; Glutathione; Glut

1986
Brain cholinergic, behavioral, and morphological development in rats exposed in utero to methylparathion.
    Toxicology and applied pharmacology, 1985, Mar-15, Volume: 77, Issue:3

    Topics: Acetylcholinesterase; Animals; Behavior, Animal; Body Weight; Brain; Choline O-Acetyltransferase; Fe

1985
Teratological examination of Wofatox 50 EC (50% methylparathion) on pheasant embryos.
    Anatomischer Anzeiger, 1985, Volume: 158, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Bird Diseases; Birds; Dose-Response Relationship, Drug; Female

1985
Comparative feto-toxicity of organophosphate insecticide in mice.
    Bulletin of epizootic diseases of Africa. Bulletin des epizooties en Afrique, 1974, Volume: 22, Issue:2

    Topics: Animals; Diazinon; Female; Fetal Death; Insecticides; Lethal Dose 50; Malathion; Methyl Parathion; M

1974
[The diagnostic and prognostic significance of transcutaneous PO2 dynamics during a functional test in "pretoxicosis" and the initial stage of gestosis].
    Akusherstvo i ginekologiia, 1990, Issue:9

    Topics: Blood Gas Monitoring, Transcutaneous; Diagnosis, Differential; Female; Humans; Nitrogen; Oxygen; Pol

1990
[Experimental evaluation of the possibility of modifying the nonspecific body resistance of mother, fetus and newborn to extreme factors].
    Akusherstvo i ginekologiia, 1986, Issue:3

    Topics: Adaptation, Physiological; Animals; Animals, Newborn; Female; Fetal Hypoxia; Fetus; Hypoxia; Immunit

1986