Compounds > methyl n-butyl ketone
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methyl n-butyl ketone and Cholestasis

methyl n-butyl ketone has been researched along with Cholestasis in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's4 (57.14)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duguay, AB; Plaa, GL1
Duguay, A; Plaa, GL1
Couture, J; Dahlström-King, L; du Souich, P; Plaa, GL1
du Souich, P; Greselin, E; Kobusch, AB; Plaa, GL; Vézina, M1
Plaa, GL; Vézina, M2
Ayotte, P; Plaa, GL1

Other Studies

7 other study(ies) available for methyl n-butyl ketone and Cholestasis

ArticleYear
Plasma concentrations in methyl isobutyl ketone-potentiated experimental cholestasis after inhalation or oral administration.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1993, Volume: 21, Issue:2

    Topics: Administration, Inhalation; Administration, Oral; Animals; Bilirubin; Cholestasis; Dose-Response Relationship, Drug; Male; Manganese; Methyl n-Butyl Ketone; Rats; Rats, Sprague-Dawley; Taurolithocholic Acid

1993
Altered cholesterol synthesis as a mechanism involved in methyl isobutyl ketone-potentiated experimental cholestasis.
    Toxicology and applied pharmacology, 1997, Volume: 147, Issue:2

    Topics: Animals; Bile Canaliculi; Bilirubin; Cholestasis; Cholestasis, Intrahepatic; Cholesterol; Drug Synergism; Liver; Male; Manganese Compounds; Manganese Poisoning; Methyl n-Butyl Ketone; Rats; Rats, Sprague-Dawley; Solvents; Subcellular Fractions; Sulfates

1997
The influence of severity of bile flow reduction, cycloheximide, and methyl isobutyl ketone pretreatment on the kinetics of taurolithocholic acid disposition in the rat.
    Toxicology and applied pharmacology, 1990, Jun-15, Volume: 104, Issue:2

    Topics: Animals; Bile; Cholestasis; Cycloheximide; Drug Synergism; Ketones; Kinetics; Lithocholic Acid; Male; Metabolic Clearance Rate; Methyl n-Butyl Ketone; Rats; Rats, Inbred Strains; Secretory Rate; Taurolithocholic Acid

1990
Potentiation of chloroform-induced hepatotoxicity by methyl isobutyl ketone and two metabolites.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:8

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Cholestasis; Densitometry; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Ketones; Male; Methyl n-Butyl Ketone; Microsomes, Liver; Mixed Function Oxygenases; Pentanols; Proteins; Rats; Rats, Inbred Strains

1990
Methyl isobutyl ketone metabolites and potentiation of the cholestasis induced in rats by a manganese-bilirubin combination or manganese alone.
    Toxicology and applied pharmacology, 1988, Mar-15, Volume: 92, Issue:3

    Topics: Animals; Bile; Bilirubin; Cholestasis; Dose-Response Relationship, Drug; Drug Synergism; Ketones; Male; Manganese Poisoning; Methyl n-Butyl Ketone; Protein Biosynthesis; Rats; Rats, Inbred Strains

1988
Potentiation by methyl isobutyl ketone of the cholestasis induced in rats by a manganese-bilirubin combination or manganese alone.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:3

    Topics: Animals; Bilirubin; Cholestasis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Ketones; Male; Manganese Poisoning; Methyl n-Butyl Ketone; Rats; Rats, Inbred Strains

1987
Taurolithocholate-induced intrahepatic cholestasis: potentiation by methyl isobutyl ketone and methyl n-butyl ketone in rats.
    Toxicology and applied pharmacology, 1985, Sep-15, Volume: 80, Issue:2

    Topics: Animals; Bile; Cholestasis; Drug Synergism; Hexanones; Injections, Intravenous; Ketones; Lithocholic Acid; Male; Methyl n-Butyl Ketone; Rats; Rats, Inbred Strains; Taurolithocholic Acid

1985