methyl methanesulfonate has been researched along with Neoplasms in 17 studies
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Correlations between the degree of malignancy, patient prognostic index and HMGA levels have been firmly established." | 1.35 | HMGA2 exhibits dRP/AP site cleavage activity and protects cancer cells from DNA-damage-induced cytotoxicity during chemotherapy. ( Bao, Q; Dröge, P; Goodman, SD; Henderson, D; Klonisch, T; Li, O; Peter, S; Sathiyanathan, P; Summer, H; Zhan, L, 2009) |
| "Thus, it is possible that tumors also pretreated with other drugs become resistant to growth inhibitory effects of ascorbate ions." | 1.27 | Effects of ascorbate ions on intracellular fluorescein emission polarization spectra in cancer and normal proliferating cells. ( Cercek, B; Cercek, L, 1987) |
| "Three in 10 patients with stomach cancer and 4 in 16 patients with other cancers were sensitive to induction of SCE by methyl methanesulfonate." | 1.27 | Novel responses of peripheral lymphocytes of cancer patients to chemical induction of sister chromatid exchanges. ( Horaguchi, K; Kikuchi, J; Nakada, T; Oikawa, A; Sugawara, R; Takahashi, K; Tohda, H; Wakui, A; Yamauchi, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (17.65) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 2 |
| Chen, J | 1 |
| Lu, Q | 1 |
| Zhang, FL | 1 |
| Lu, DY | 1 |
| Shao, ZM | 1 |
| Li, DQ | 1 |
| Summer, H | 1 |
| Li, O | 1 |
| Bao, Q | 1 |
| Zhan, L | 1 |
| Peter, S | 1 |
| Sathiyanathan, P | 1 |
| Henderson, D | 1 |
| Klonisch, T | 1 |
| Goodman, SD | 1 |
| Dröge, P | 1 |
| Park, JY | 1 |
| Song, JY | 1 |
| Kim, HM | 1 |
| Han, HS | 1 |
| Seol, HS | 1 |
| Jang, SJ | 1 |
| Choi, J | 1 |
| Stathopoulou, A | 1 |
| Roukos, V | 1 |
| Petropoulou, C | 1 |
| Kotsantis, P | 1 |
| Karantzelis, N | 1 |
| Nishitani, H | 1 |
| Lygerou, Z | 1 |
| Taraviras, S | 1 |
| Roberts, SA | 1 |
| Sterling, J | 1 |
| Thompson, C | 1 |
| Harris, S | 1 |
| Mav, D | 1 |
| Shah, R | 1 |
| Klimczak, LJ | 1 |
| Kryukov, GV | 1 |
| Malc, E | 1 |
| Mieczkowski, PA | 1 |
| Resnick, MA | 1 |
| Gordenin, DA | 1 |
| Kaufmann, WK | 1 |
| Lee, MY | 1 |
| Kim, MA | 1 |
| Kim, HJ | 1 |
| Bae, YS | 1 |
| Park, JI | 1 |
| Kwak, JY | 1 |
| Chung, JH | 1 |
| Yun, J | 1 |
| Wilson, PF | 1 |
| Wong, HK | 1 |
| Urbin, SS | 1 |
| Thompson, LH | 1 |
| Wilson, DM | 1 |
| Janion, C | 1 |
| Glassner, BJ | 1 |
| Rasmussen, LJ | 1 |
| Najarian, MT | 1 |
| Posnick, LM | 1 |
| Samson, LD | 1 |
| Seo, YR | 1 |
| Fishel, ML | 1 |
| Amundson, S | 1 |
| Kelley, MR | 1 |
| Smith, ML | 1 |
| Erickson, LC | 1 |
| Fornace, AJ | 1 |
| Papathanasiou, MA | 1 |
| Hollander, MC | 1 |
| Yarosh, DB | 1 |
| Cercek, L | 1 |
| Cercek, B | 1 |
| Oikawa, A | 1 |
| Horaguchi, K | 1 |
| Sugawara, R | 1 |
| Kikuchi, J | 1 |
| Tohda, H | 1 |
| Takahashi, K | 1 |
| Wakui, A | 1 |
| Yamauchi, A | 1 |
| Nakada, T | 1 |
| Smith, DB | 1 |
| Fox, BW | 1 |
| Thatcher, N | 1 |
| Steward, WP | 1 |
| Scarffe, JH | 1 |
| Wagstaff, J | 1 |
| Vezin, R | 1 |
| Crowther, D | 1 |
3 reviews available for methyl methanesulfonate and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Mechanisms of action of methyl methanesulfonate on Escherichia coli: mutagenesis, DNA damage and repair.
Topics: Alkylating Agents; DNA Damage; DNA Repair; DNA Replication; DNA, Bacterial; Escherichia coli; Humans | 1995 |
The role of O-6 methylguanine DNA methyltransferase (MGMT) in drug resistance and strategies for its inhibition.
Topics: Animals; DNA Repair; Drug Resistance; Ethylnitrosourea; Guanine; Humans; Methyl Methanesulfonate; Me | 1991 |
14 other studies available for methyl methanesulfonate and Neoplasms
| Article | Year |
|---|---|
USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells.
Topics: Antineoplastic Agents; BRCA1 Protein; Cell Line, Tumor; Cyanoacrylates; Drug Resistance, Neoplasm; G | 2019 |
HMGA2 exhibits dRP/AP site cleavage activity and protects cancer cells from DNA-damage-induced cytotoxicity during chemotherapy.
Topics: Antineoplastic Agents; AT-Hook Motifs; Cell Line, Tumor; DNA Damage; DNA Repair; DNA-(Apurinic or Ap | 2009 |
p53-Independent expression of wild-type p53-induced phosphatase 1 (Wip1) in methylmethane sulfonate-treated cancer cell lines and human tumors.
Topics: Base Sequence; Blotting, Western; Cell Line, Tumor; DNA Primers; Gene Silencing; Humans; Methyl Meth | 2012 |
Cdt1 is differentially targeted for degradation by anticancer chemotherapeutic drugs.
Topics: Antineoplastic Agents; Cell Cycle Proteins; Cisplatin; Doxorubicin; Etoposide; Fluorouracil; HeLa Ce | 2012 |
Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.
Topics: Amino Acid Transport Systems, Basic; DNA Breaks, Double-Stranded; DNA Methylation; DNA Repair; DNA, | 2012 |
Mutational showers during carcinogenesis.
Topics: Cell Transformation, Neoplastic; DNA Replication; DNA, Fungal; Genome, Human; Humans; Melanoma; Meth | 2012 |
Alkylating agent methyl methanesulfonate (MMS) induces a wave of global protein hyperacetylation: implications in cancer cell death.
Topics: Acetylation; Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Dose-Response Relations | 2007 |
XRCC1 down-regulation in human cells leads to DNA-damaging agent hypersensitivity, elevated sister chromatid exchange, and reduced survival of BRCA2 mutant cells.
Topics: Animals; BRCA2 Protein; Cell Extracts; Cell Survival; CHO Cells; Chromosomal Instability; Cricetinae | 2007 |
Generation of a strong mutator phenotype in yeast by imbalanced base excision repair.
Topics: Carbon-Oxygen Lyases; Deoxyribonuclease IV (Phage T4-Induced); DNA Glycosylases; DNA Repair; DNA-(Ap | 1998 |
Implication of p53 in base excision DNA repair: in vivo evidence.
Topics: Animals; Apoptosis; Carbon-Oxygen Lyases; Cell Cycle; Cell Line; Comet Assay; DNA Damage; DNA Polyme | 2002 |
Expression of the O6-methylguanine-DNA methyltransferase gene MGMT in MER+ and MER- human tumor cells.
Topics: Cell Line; Gene Expression; Humans; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methyltran | 1990 |
Effects of ascorbate ions on intracellular fluorescein emission polarization spectra in cancer and normal proliferating cells.
Topics: 2,4-Dinitrophenol; Ascorbic Acid; Calcium; Cell Line; Cyclic AMP; Cytochalasin B; Demecolcine; Dinit | 1987 |
Novel responses of peripheral lymphocytes of cancer patients to chemical induction of sister chromatid exchanges.
Topics: 4-Nitroquinoline-1-oxide; Aged; Carbolines; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Lymph | 1986 |
Phase I clinical trial of methylene dimethane sulfonate.
Topics: Adult; Aged; Alkylating Agents; Drug Evaluation; Female; Humans; Male; Methyl Methanesulfonate; Midd | 1987 |