methyl methanesulfonate has been researched along with Necrosis in 9 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methyl methanesulfonate (MMS) is an alkylating agent that can induce cell death through apoptosis and necroptosis." | 5.43 | Methyl methanesulfonate induces necroptosis in human lung adenoma A549 cells through the PIG-3-reactive oxygen species pathway. ( Chi, L; Gao, X; Jiang, Y; Li, H; Shan, S; Yang, J; Zhang, G; Zhu, X, 2016) |
| " A highly cytotoxic concentration of the DNA methylating agent methyl methanesulfonate (MMS) results in cellular ATP depletion and cell death primarily by necrosis in both wild-type and DNA polymerase beta null mouse fibroblasts." | 3.73 | Involvement of poly(ADP-ribose) polymerase activity in regulating Chk1-dependent apoptotic cell death. ( Horton, JK; Stefanick, DF; Wilson, SH, 2005) |
| "Methyl methanesulfonate (MMS) is an alkylating agent that can induce cell death through apoptosis and necroptosis." | 1.43 | Methyl methanesulfonate induces necroptosis in human lung adenoma A549 cells through the PIG-3-reactive oxygen species pathway. ( Chi, L; Gao, X; Jiang, Y; Li, H; Shan, S; Yang, J; Zhang, G; Zhu, X, 2016) |
| "Programmed necrosis is important in many (patho)physiological settings." | 1.40 | TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death. ( Adam, D; Chan, FK; Davarnia, P; Herdegen, T; Kabelitz, D; Lange, A; Linkermann, A; Mathieu, S; Rittger, A; Schütze, S; Sosna, J; Thon, L; Voigt, S, 2014) |
| "With chromosomal aberrations as the endpoint, the sensitivity of the double-knockout cells was between wild-type and single-knockouts." | 1.31 | Effect of ultraviolet light, methyl methanesulfonate and ionizing radiation on the genotoxic response and apoptosis of mouse fibroblasts lacking c-Fos, p53 or both. ( Eichhorn, U; Kaina, B; Lackinger, D, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sosna, J | 1 |
| Voigt, S | 1 |
| Mathieu, S | 1 |
| Lange, A | 1 |
| Thon, L | 1 |
| Davarnia, P | 1 |
| Herdegen, T | 1 |
| Linkermann, A | 1 |
| Rittger, A | 1 |
| Chan, FK | 1 |
| Kabelitz, D | 1 |
| Schütze, S | 1 |
| Adam, D | 1 |
| Jiang, Y | 1 |
| Shan, S | 1 |
| Chi, L | 1 |
| Zhang, G | 1 |
| Gao, X | 1 |
| Li, H | 1 |
| Zhu, X | 1 |
| Yang, J | 1 |
| Gassman, NR | 1 |
| Stefanick, DF | 2 |
| Kedar, PS | 1 |
| Horton, JK | 2 |
| Wilson, SH | 3 |
| Bakkali, F | 1 |
| Averbeck, S | 1 |
| Averbeck, D | 1 |
| Zhiri, A | 1 |
| Baudoux, D | 1 |
| Idaomar, M | 1 |
| Mlejnek, P | 1 |
| Frydrych, I | 1 |
| Dolezel, P | 1 |
| Ochs, K | 1 |
| Sobol, RW | 1 |
| Kaina, B | 2 |
| Liu, W | 1 |
| Linn, S | 1 |
| Lackinger, D | 1 |
| Eichhorn, U | 1 |
9 other studies available for methyl methanesulfonate and Necrosis
| Article | Year |
|---|---|
TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Benzamides; Calpain; Cathepsins; Cell Line; C | 2014 |
Methyl methanesulfonate induces necroptosis in human lung adenoma A549 cells through the PIG-3-reactive oxygen species pathway.
Topics: A549 Cells; Adenoma; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Cell Survival; | 2016 |
Hyperactivation of PARP triggers nonhomologous end-joining in repair-deficient mouse fibroblasts.
Topics: Animals; Antigens, Nuclear; DNA Damage; DNA End-Joining Repair; DNA Repair; DNA-Activated Protein Ki | 2012 |
Involvement of poly(ADP-ribose) polymerase activity in regulating Chk1-dependent apoptotic cell death.
Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase Inhibitors; Cel | 2005 |
Antigenotoxic effects of three essential oils in diploid yeast (Saccharomyces cerevisiae) after treatments with UVC radiation, 8-MOP plus UVA and MMS.
Topics: Apoptosis; Artemisia; Cell Survival; Cinnamomum camphora; Cytoplasm; Diploidy; Dose-Response Relatio | 2006 |
Cyclosporin A potentiates the cytotoxic effects of methyl methanesulphonate in HL-60 and K562 cells.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caspase 3; Cell Survival; Cyclos | 2007 |
Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage.
Topics: Alkylating Agents; Animals; Apoptosis; Chromosome Aberrations; DNA Damage; DNA Polymerase beta; DNA | 1999 |
Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis.
Topics: Amino Acid Sequence; Apoptosis; Binding Sites; Blotting, Western; Calpain; Caspase 3; Caspases; Cata | 2000 |
Effect of ultraviolet light, methyl methanesulfonate and ionizing radiation on the genotoxic response and apoptosis of mouse fibroblasts lacking c-Fos, p53 or both.
Topics: Animals; Apoptosis; Blotting, Northern; Blotting, Western; Cell Line; Cell Survival; Cells, Cultured | 2001 |