methyl methanesulfonate has been researched along with Melanoma in 4 studies
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the human melanoma cell line MM127 , the melphalan survival curve was linear and exhibited reciprocity with respect to concentration and treatment time." | 7.67 | Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines. ( Parsons, PG, 1984) |
| " Dose-response experiments, which included 10 dose levels, were performed, the data analyzed by linear regression, and the slope of the regression line (term: G0) used as a measure of DNA repair synthesis." | 5.27 | DNA repair synthesis in fibroblast strains from patients with actinic keratosis, squamous cell carcinoma, basal cell carcinoma, or malignant melanoma after treatment with ultraviolet light, N-acetoxy-2-acetyl-aminofluorene, methyl methanesulfonate, and N- ( Burkhardt, MR; Edler, L; Jung, EG; Thielmann, HW, 1987) |
| "In the human melanoma cell line MM127 , the melphalan survival curve was linear and exhibited reciprocity with respect to concentration and treatment time." | 3.67 | Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines. ( Parsons, PG, 1984) |
| " Dose-response experiments, which included 10 dose levels, were performed, the data analyzed by linear regression, and the slope of the regression line (term: G0) used as a measure of DNA repair synthesis." | 1.27 | DNA repair synthesis in fibroblast strains from patients with actinic keratosis, squamous cell carcinoma, basal cell carcinoma, or malignant melanoma after treatment with ultraviolet light, N-acetoxy-2-acetyl-aminofluorene, methyl methanesulfonate, and N- ( Burkhardt, MR; Edler, L; Jung, EG; Thielmann, HW, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaufmann, WK | 1 |
| Hattori, T | 1 |
| Ohoka, N | 1 |
| Inoue, Y | 1 |
| Hayashi, H | 1 |
| Onozaki, K | 1 |
| Parsons, PG | 1 |
| Thielmann, HW | 1 |
| Edler, L | 1 |
| Burkhardt, MR | 1 |
| Jung, EG | 1 |
4 other studies available for methyl methanesulfonate and Melanoma
| Article | Year |
|---|---|
Mutational showers during carcinogenesis.
Topics: Cell Transformation, Neoplastic; DNA Replication; DNA, Fungal; Genome, Human; Humans; Melanoma; Meth | 2012 |
C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer.
Topics: Carcinoma, Squamous Cell; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Proteins; Cell | 2003 |
Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines.
Topics: Caffeine; Cell Line; Cell Survival; Chlorambucil; DNA, Neoplasm; Drug Resistance; Drug Synergism; Ho | 1984 |
DNA repair synthesis in fibroblast strains from patients with actinic keratosis, squamous cell carcinoma, basal cell carcinoma, or malignant melanoma after treatment with ultraviolet light, N-acetoxy-2-acetyl-aminofluorene, methyl methanesulfonate, and N-
Topics: Acetoxyacetylaminofluorene; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cells, Cultured; DNA Re | 1987 |