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methyl methanesulfonate and Lymphoma

methyl methanesulfonate has been researched along with Lymphoma in 20 studies

Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.

Research Excerpts

ExcerptRelevanceReference
" We have investigated gene expression changes in L5178Y TK(+/-) mouse lymphoma cells in culture following treatment with methyl methanesulfonate (MMS), a direct acting genotoxin, and sodium chloride (NaCl), which induces mutations in these cells through indirect mechanisms at high concentrations."7.72Profiles of gene expression changes in L5178Y mouse lymphoma cells treated with methyl methanesulfonate and sodium chloride. ( Gollapudi, BB; Kan, HL; Linscombe, VA; Schisler, MR; Seidel, SD; Sparrow, BR; Stott, WT, 2004)
" This study was designed to investigate the effects of endogenous GH on apoptosis induced by methyl methanesulfonate (MMS) in a T cell lymphoma overexpressing GH (GHo)."3.72The inhibition of apoptosis in EL4 lymphoma cells overexpressing growth hormone. ( Arnold, RE; Weigent, DA, 2004)
" We have investigated gene expression changes in L5178Y TK(+/-) mouse lymphoma cells in culture following treatment with methyl methanesulfonate (MMS), a direct acting genotoxin, and sodium chloride (NaCl), which induces mutations in these cells through indirect mechanisms at high concentrations."3.72Profiles of gene expression changes in L5178Y mouse lymphoma cells treated with methyl methanesulfonate and sodium chloride. ( Gollapudi, BB; Kan, HL; Linscombe, VA; Schisler, MR; Seidel, SD; Sparrow, BR; Stott, WT, 2004)
" We used Affymetrix microarrays to detect gene expression changes in mouse lymphoma (L5178Y) and human lymphoblastoid (TK6) cells in response to methyl methanesulfonate (MMS; a prototypical alkylating agent) and bleomycin (a prototypical oxidative mutagen)."3.72Comparison of gene expression changes induced in mouse and human cells treated with direct-acting mutagens. ( Altizer, JL; Deahl, JT; Islaih, M; Kadura, IA; Li, B; Newton, RK; Reid-Hubbard, JL; Watson, DE, 2004)
"Luria-Delbrück fluctuation tests for the determination of the spontaneous mutation rate to ouabain resistance incultured L5178Y mouse lymphoma cells gave values in the range 0."3.65The fluctuation test as a more sensitive system for determining induced mutation in L5178Y mouse lymphoma cells. ( Arlett, CF; Cole, J; Green, MH, 1976)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199010 (50.00)18.7374
1990's4 (20.00)18.2507
2000's6 (30.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arnold, RE3
Weigent, DA3
Seidel, SD1
Sparrow, BR1
Kan, HL1
Stott, WT1
Schisler, MR1
Linscombe, VA1
Gollapudi, BB1
Shuai, PQ1
Zhang, LS2
Wang, YJ1
Islaih, M1
Li, B1
Kadura, IA1
Reid-Hubbard, JL1
Deahl, JT1
Altizer, JL1
Watson, DE1
Newton, RK1
Pearson, CM1
Styles, JA1
Amacher, DE1
Paillet, SC1
Honma, M1
Hayashi, M1
Suzuki, T1
Matsuoka, A1
Sofuni, T1
Frei, JV1
Lawley, PD1
Cole, J3
Arlett, CF2
Raikow, RB1
Meredith, RF1
Brozovich, BJ1
Seeman, PR1
Livingston, AE1
Okunewick, JP1
Sato, K1
Hieda, N1
Green, MH1
Moore, MM2
Parker, L1
Huston, J1
Harrington-Brock, K1
Dearfield, KL1
McGregor, D1
Brown, AG1
Cattanach, P1
Edwards, I1
McBride, D1
Riach, C1
Shepherd, W1
Caspary, WJ1
Diot, MC1
Richmond, FN1
Bridges, BA1
Segal, A1
Seidman, I1
Melchionne, S1
Albert, RE1
Upton, AC1
Tarlo, KS1
Boehnke, M1
Chin, B1
Meyer, M1
Brock, K1
Lawrence, K1
Casto, B1

Other Studies

20 other studies available for methyl methanesulfonate and Lymphoma

ArticleYear
The production of nitric oxide in EL4 lymphoma cells overexpressing growth hormone.
    Journal of neuroimmunology, 2003, Volume: 134, Issue:1-2

    Topics: Animals; Arginine; Carbocyanines; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Culture

2003
The inhibition of apoptosis in EL4 lymphoma cells overexpressing growth hormone.
    Neuroimmunomodulation, 2004, Volume: 11, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Antibodies; Apoptosis; bcl-2-Associated X Protein; bcl-Associated D

2004
Profiles of gene expression changes in L5178Y mouse lymphoma cells treated with methyl methanesulfonate and sodium chloride.
    Mutagenesis, 2004, Volume: 19, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Gene Expression; Gene Expression Regulation, Neoplastic;

2004
[TK locus mutation assay: comparison of L5178Y and TK6 cell lines].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2004, Volume: 35, Issue:5

    Topics: Animals; Cell Line, Tumor; Ethyl Methanesulfonate; Humans; Leukemia L5178; Lymphoma; Methyl Methanes

2004
Comparison of gene expression changes induced in mouse and human cells treated with direct-acting mutagens.
    Environmental and molecular mutagenesis, 2004, Volume: 44, Issue:5

    Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Bleomycin; DNA, Neoplasm; Gene Expression P

2004
Expression of insulin-like growth factor-1 and insulin-like growth factor-1 receptors in EL4 lymphoma cells overexpressing growth hormone.
    Cellular immunology, 2005, Volume: 234, Issue:1

    Topics: Animals; Antibodies; Apoptosis; Binding Sites; Cell Line, Tumor; Enzyme Activation; Gene Expression

2005
Resistance of mouse lymphoma L5178YAII cells to alkylation with methylmethane sulphonate resides in a late step of excision repair.
    Journal of cell science, 1984, Volume: 68

    Topics: Alkylation; Animals; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; DNA Ligases; DN

1984
Trifluorothymidine resistance and colony size in L5178Y/TK +/- cells treated with methyl methanesulfonate.
    Journal of cellular physiology, 1981, Volume: 106, Issue:3

    Topics: Animals; Cell Division; Cell Line; Cell Survival; Clone Cells; Drug Resistance; Genetic Variation; K

1981
A comparative study of TK6 human lymphoblastoid and L5178Y mouse lymphoma cell lines in the in vitro micronucleus test.
    Mutation research, 1995, Volume: 347, Issue:3-4

    Topics: Animals; B-Lymphocytes; Cell Line; Cell Survival; Demecolcine; Ethyl Methanesulfonate; Humans; Leuke

1995
Tissue distribution and mode of DNA methylation in mice by methyl methanesulphonate and N-methyl-N' -nitro-N-nitrosoguanidine: lack of thymic lymphoma induction and low extent of methylation of target tissue DNA at 0-6 of guanine.
    Chemico-biological interactions, 1976, Volume: 13, Issue:3-4

    Topics: Animals; Carcinogens; DNA; Female; Guanine; Lymphoma; Mesylates; Methyl Methanesulfonate; Methylnitr

1976
Methyl methanesulphonate mutagenesis in L5178Y mouse lymphoma cells.
    Mutation research, 1978, Volume: 50, Issue:1

    Topics: Cell Line; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Lymphoma; Mesy

1978
Potentiating effect of methyl methane sulfonate on Friend virus leukemogenesis in vivo.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1979, Volume: 161, Issue:2

    Topics: Animals; Antibody-Producing Cells; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Le

1979
Isolation and characterization of a mutant mouse lymphoma cell sensitive to methyl methanesulfonate and X rays.
    Radiation research, 1979, Volume: 78, Issue:1

    Topics: Animals; Cell Survival; Cytological Techniques; Lymphoma; Mesylates; Methyl Methanesulfonate; Mice;

1979
The fluctuation test as a more sensitive system for determining induced mutation in L5178Y mouse lymphoma cells.
    Mutation research, 1976, Volume: 41, Issue:2-3

    Topics: Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Genetic

1976
Comparison of mutagenicity results for nine compounds evaluated at the hgprt locus in the standard and suspension CHO assays.
    Mutagenesis, 1991, Volume: 6, Issue:1

    Topics: Acrylates; Aminoacridines; Animals; Cell Line; Chromosome Aberrations; Cricetinae; Dose-Response Rel

1991
Responses of the L5178Y mouse lymphoma forward mutation assay: V. Gases and vapors.
    Environmental and molecular mutagenesis, 1991, Volume: 17, Issue:2

    Topics: Air Pollutants; Alkenes; Animals; Butadienes; Dichloroethylenes; Epoxy Compounds; Ethyl Methanesulfo

1991
Comparative induction of gene mutations and chromosome damage by 1-methoxy-1,3,5-cycloheptatriene (MCHT), 2. Results using L5178Y mouse lymphoma cells to detect both gene and chromosome damage; validation with ionizing radiation, methyl methanesulphonate,
    Mutation research, 1990, Volume: 230, Issue:1

    Topics: Animals; Benzo(a)pyrene; Chromosome Aberrations; Chromosomes; Cloning, Molecular; Cycloheptanes; DNA

1990
Rapid induction of thymic lymphomas by isopropyl methanesulfonate: a preliminary report.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 183, Issue:1

    Topics: Animals; Female; Lymphatic Diseases; Lymphoma; Mesylates; Methyl Methanesulfonate; Mice; Mice, Inbre

1986
Synergism of mutant frequencies in the mouse lymphoma cell mutagenicity assay by binary mixtures of methyl methanesulfonate and ethyl methanesulfonate.
    Mutation research, 1988, Volume: 206, Issue:2

    Topics: Animals; Drug Synergism; Ethyl Methanesulfonate; Lymphoma; Methyl Methanesulfonate; Mice; Mutagenici

1988
Evaluation of the effect of agar on the results obtained in the L5178Y mouse lymphoma assay.
    Environmental mutagenesis, 1986, Volume: 8, Issue:5

    Topics: Agar; Animals; Cell Division; Cell Survival; Lymphoma; Methyl Methanesulfonate; Mice; Mutagenicity T

1986