methyl methanesulfonate has been researched along with Cell Transformation, Neoplastic in 22 studies
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methyl methanesulfonate (MMS) was used to convert premalignant squamous cell carcinoma (SCC) cell line SCC-83-01-82 to a malignant phenotype." | 1.28 | Nontumorigenic squamous cell carcinoma line converted to tumorigenicity with methyl methanesulfonate without activation of HRAS or MYC. ( French, BT; Hollering, J; Kurian, P; Mannix, DG; Milo, GE; Noyes, I; Schuller, D; Shuler, C; Sital, N; Trewyn, RW, 1990) |
| "The induction of neoplastic cell transformation is closely associated with DNA alterations which occur shortly after carcinogen exposure." | 1.27 | Persistence of sister chromatid exchanges and in vitro morphological transformation of Syrian hamster fetal cells by chemical and physical carcinogens. ( Amsbaugh, SC; DiPaolo, JA; Popescu, NC, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (72.73) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaufmann, WK | 1 |
| Lang, T | 1 |
| Dalal, S | 1 |
| Chikova, A | 1 |
| DiMaio, D | 1 |
| Sweasy, JB | 1 |
| Henderson, EE | 1 |
| Ribecky, R | 1 |
| Popescu, NC | 3 |
| DiPaolo, JA | 7 |
| Amsbaugh, SC | 2 |
| Oshiro, Y | 1 |
| Balwierz, PS | 1 |
| Molinary, SV | 1 |
| Doniger, J | 2 |
| Milo, GE | 3 |
| Li, D | 1 |
| Casto, BC | 2 |
| Theil, K | 1 |
| Shuler, C | 3 |
| Noyes, I | 3 |
| Chen, J | 1 |
| Sevignani, C | 1 |
| Cranston, A | 1 |
| Iozzo, RV | 1 |
| Fishel, R | 1 |
| Calabretta, B | 1 |
| Myhr, BC | 1 |
| Higgins, NP | 1 |
| Strauss, BS | 1 |
| Peterson, AR | 1 |
| Peterson, H | 1 |
| Heidelberger, C | 1 |
| Pieczynski, WJ | 1 |
| Janosko, N | 1 |
| Kurian, P | 2 |
| French, BT | 2 |
| Sital, N | 2 |
| Hollering, J | 2 |
| Trewyn, RW | 2 |
| Schuller, D | 2 |
| Mannix, DG | 1 |
| Cleaver, JE | 1 |
| Banda, MJ | 1 |
| Troll, W | 1 |
| Borek, C | 1 |
| Hermo, H | 1 |
| Duigou, GJ | 1 |
| Zimmer, SG | 1 |
| Fisher, PB | 1 |
| Yano, K | 1 |
| Sonoda, M | 1 |
| Sakagishi, Y | 1 |
| Sakamoto, Y | 1 |
| Uyemura, K | 1 |
| Jan, KY | 1 |
| Huang, RY | 1 |
| Lee, TC | 1 |
| Day, RS | 1 |
| Schechtman, LM | 1 |
1 review available for methyl methanesulfonate and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
BALB/c 3T3 cell transformation: protocols, problems and improvements.
Topics: Animals; Biotransformation; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Me | 1985 |
21 other studies available for methyl methanesulfonate and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Mutational showers during carcinogenesis.
Topics: Cell Transformation, Neoplastic; DNA Replication; DNA, Fungal; Genome, Human; Humans; Melanoma; Meth | 2012 |
The E295K DNA polymerase beta gastric cancer-associated variant interferes with base excision repair and induces cellular transformation.
Topics: Animals; Cell Transformation, Neoplastic; DNA Polymerase beta; DNA Primers; DNA Repair; Embryo, Mamm | 2007 |
Transformation of human leukocytes with Epstein-Barr virus after cellular exposure to chemical or physical mutagens.
Topics: Cell Transformation, Neoplastic; Cells, Cultured; Herpesvirus 4, Human; Humans; Leukocytes; Methyl M | 1980 |
Quantitative comparison between SCE and transformation frequencies induced by chemical carcinogens in Syrian hamster cells.
Topics: Acetoxyacetylaminofluorene; Animals; Benzo(a)pyrene; Carcinogens; Cell Line; Cell Transformation, Ne | 1984 |
Relationship of carcinogen-induced sister chromatid exchange and neoplastic cell transformation.
Topics: Acetoxyacetylaminofluorene; Animals; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cel | 1981 |
Morphological transformation of C3H/10T1/2 CL8 cells by alkylating agents.
Topics: Alkylating Agents; Animals; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Drug Evaluation, | 1981 |
Excision and postreplication DNA repair capacities, enhanced transformation, and survival of Syrian hamster embryo cells irradiated by ultraviolet light.
Topics: Animals; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA Repair; Me | 1980 |
Malignant conversion of chemically transformed normal human cells.
Topics: Aflatoxin B1; Animals; Avian Sarcoma Viruses; Base Sequence; Blotting, Southern; Carcinogens; Carcin | 1996 |
Spontaneous and mutagen-induced transformation of primary cultures of Msh2-/- p53-/- colonocytes.
Topics: Animals; Base Pair Mismatch; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Colon; | 1999 |
Mutagenesis of Chinese hamster cells in vitro by combination treatments with methyl methanesulfonate and N-acetoxy-2-acetylaminofluorene.
Topics: Acetoxyacetylaminofluorene; Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cric | 1978 |
Differences in the ability of human lymphoblastoid lines to exclude bromodeoxyuridine and in their sensitivity to methyl methanesulfonate and to incorporated [3H]thymidine.
Topics: Bromodeoxyuridine; Burkitt Lymphoma; Cell Line; Cell Survival; Cell Transformation, Neoplastic; DNA | 1979 |
Oncogenesis, mutagenesis, DNA damage, and cytotoxicity in cultured mammalian cells treated with alkylating agents.
Topics: Alkylating Agents; Cell Line; Cell Survival; Cell Transformation, Neoplastic; DNA Repair; Dose-Respo | 1979 |
Significance of treatment interval and DNA repair in the enhancement of viral transformation by chemical carcinogens and mutagens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetoxyacetylaminofluorene; Adenoviridae; Aflatoxins; Benzopyrenes | 1976 |
Noncorrelative c-myc and ras oncogene expression in squamous cell carcinoma cells with tumorigenic potential.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Blotting, Northern; Carcinom | 1990 |
Nontumorigenic squamous cell carcinoma line converted to tumorigenicity with methyl methanesulfonate without activation of HRAS or MYC.
Topics: Animals; Blotting, Southern; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; D | 1990 |
Some protease inhibitors are also inhibitors of poly(ADP-ribose) polymerase.
Topics: Antipain; Benzamides; Caffeine; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Lymphocyte | 1986 |
Effect of methyl methanesulfonate on type 5 adenovirus DNA integration and the phenotypic properties of cold-sensitive type 5 adenovirus-transformed cloned rat embryo fibroblast cells.
Topics: Adenoviruses, Human; Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Clone Cells; | 1988 |
Reactions of ultimate carcinogens with cell membranes: importance of carbamoylation of phosphatidylethanolamine by the carcinogens.
Topics: Animals; Cell Membrane; Cell Transformation, Neoplastic; Chickens; Erythrocyte Membrane; Kidney; Mag | 1988 |
Different modes of action of sodium arsenite, 3-aminobenzamide, and caffeine on the enhancement of ethyl methanesulfonate clastogenicity.
Topics: Animals; Arsenic; Arsenites; Benzamides; Caffeine; Cell Cycle; Cell Line; Cell Transformation, Neopl | 1986 |
Quantitative assessment of the role of O6-methylguanine in the initiation of carcinogenesis by methylating agents.
Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; DNA; Dose-Response Relationship, Drug; Female; | 1985 |
Persistence of sister chromatid exchanges and in vitro morphological transformation of Syrian hamster fetal cells by chemical and physical carcinogens.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; | 1985 |