methyl methanesulfonate has been researched along with Carcinoma, Epidermoid in 11 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response experiments, which included 10 dose levels, were performed, the data analyzed by linear regression, and the slope of the regression line (term: G0) used as a measure of DNA repair synthesis." | 5.27 | DNA repair synthesis in fibroblast strains from patients with actinic keratosis, squamous cell carcinoma, basal cell carcinoma, or malignant melanoma after treatment with ultraviolet light, N-acetoxy-2-acetyl-aminofluorene, methyl methanesulfonate, and N- ( Burkhardt, MR; Edler, L; Jung, EG; Thielmann, HW, 1987) |
| "Methyl methanesulfonate (MMS) was used to convert premalignant squamous cell carcinoma (SCC) cell line SCC-83-01-82 to a malignant phenotype." | 1.28 | Nontumorigenic squamous cell carcinoma line converted to tumorigenicity with methyl methanesulfonate without activation of HRAS or MYC. ( French, BT; Hollering, J; Kurian, P; Mannix, DG; Milo, GE; Noyes, I; Schuller, D; Shuler, C; Sital, N; Trewyn, RW, 1990) |
| "Rat nasal squamous cell carcinomas induced by inhalation of three direct-acting alkylating agents yielded DNA containing activated oncogenes with no homology to any member of the ras family." | 1.27 | Detection of novel non-ras oncogenes in rat nasal squamous cell carcinomas. ( Currie, DD; Felber, M; Garte, SJ; Hochwalt, AE; Wirgin, I, 1988) |
| "Neither squamous cell carcinomas nor thymic lymphomas were observed in 30 mice following topical application of MMS." | 1.27 | Induction of thymic lymphomas and squamous cell carcinomas following topic application of isopropyl methanesulfonate to female Hsd:(ICR)BR mice. ( Melchionne, S; Segal, A; Seidman, I, 1987) |
| " Dose-response experiments, which included 10 dose levels, were performed, the data analyzed by linear regression, and the slope of the regression line (term: G0) used as a measure of DNA repair synthesis." | 1.27 | DNA repair synthesis in fibroblast strains from patients with actinic keratosis, squamous cell carcinoma, basal cell carcinoma, or malignant melanoma after treatment with ultraviolet light, N-acetoxy-2-acetyl-aminofluorene, methyl methanesulfonate, and N- ( Burkhardt, MR; Edler, L; Jung, EG; Thielmann, HW, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carvalho, JG | 1 |
| Noguti, J | 1 |
| da Silva, VH | 1 |
| Dedivitis, RA | 1 |
| Franco, M | 1 |
| Ribeiro, DA | 1 |
| Hattori, T | 1 |
| Ohoka, N | 1 |
| Inoue, Y | 1 |
| Hayashi, H | 1 |
| Onozaki, K | 1 |
| Lawrence, JN | 1 |
| Benford, DJ | 1 |
| Lee, H | 1 |
| Li, D | 1 |
| Prior, T | 1 |
| Casto, BC | 1 |
| Weghorst, CM | 1 |
| Shuler, CF | 1 |
| Milo, GE | 3 |
| Sheikh, MS | 1 |
| Huang, Y | 1 |
| Fernandez-Salas, EA | 1 |
| El-Deiry, WS | 1 |
| Friess, H | 1 |
| Amundson, S | 1 |
| Yin, J | 1 |
| Meltzer, SJ | 1 |
| Holbrook, NJ | 1 |
| Fornace, AJ | 1 |
| Kim, YC | 1 |
| Koh, JT | 1 |
| Shin, BA | 1 |
| Ahn, KY | 1 |
| Choi, BK | 1 |
| Kim, CG | 1 |
| Kim, KK | 1 |
| Shuler, C | 2 |
| Kurian, P | 2 |
| French, BT | 2 |
| Noyes, I | 2 |
| Sital, N | 2 |
| Hollering, J | 2 |
| Trewyn, RW | 2 |
| Schuller, D | 2 |
| Mannix, DG | 1 |
| Hochwalt, AE | 1 |
| Wirgin, I | 1 |
| Felber, M | 1 |
| Currie, DD | 1 |
| Garte, SJ | 1 |
| Segal, A | 1 |
| Seidman, I | 1 |
| Melchionne, S | 1 |
| Thielmann, HW | 1 |
| Edler, L | 1 |
| Burkhardt, MR | 1 |
| Jung, EG | 1 |
11 other studies available for methyl methanesulfonate and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Alkylation-induced genotoxicity as a predictor of DNA repair deficiency following experimental oral carcinogenesis.
Topics: 4-Nitroquinoline-1-oxide; Administration, Oral; Alkylation; Animals; Carcinogens; Carcinoma, Squamou | 2012 |
C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer.
Topics: Carcinoma, Squamous Cell; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Proteins; Cell | 2003 |
Chemically-induced unscheduled DNA synthesis in cultures of adult human epidermal keratinocytes.
Topics: Adult; Benzo(a)pyrene; Carcinogenicity Tests; Carcinoma, Squamous Cell; Cells, Cultured; DNA; DNA Da | 1993 |
Ineffectiveness of the presence of H-ras/p53 combination of mutations in squamous cell carcinoma cells to induce a conversion of a nontumorigenic to a tumorigenic phenotype.
Topics: Animals; Autoradiography; Blotting, Northern; Carcinoma, Squamous Cell; DNA, Complementary; Gene Exp | 1997 |
The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma; | 1999 |
An antisense construct of full-length human RAD50 cDNA confers sensitivity to ionizing radiation and alkylating agents on human cell lines.
Topics: Acid Anhydride Hydrolases; Alkylating Agents; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; C | 2002 |
Noncorrelative c-myc and ras oncogene expression in squamous cell carcinoma cells with tumorigenic potential.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Blotting, Northern; Carcinom | 1990 |
Nontumorigenic squamous cell carcinoma line converted to tumorigenicity with methyl methanesulfonate without activation of HRAS or MYC.
Topics: Animals; Blotting, Southern; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; D | 1990 |
Detection of novel non-ras oncogenes in rat nasal squamous cell carcinomas.
Topics: Animals; Blotting, Southern; Carbamates; Carcinoma, Squamous Cell; Disease Models, Animal; DNA Restr | 1988 |
Induction of thymic lymphomas and squamous cell carcinomas following topic application of isopropyl methanesulfonate to female Hsd:(ICR)BR mice.
Topics: Administration, Topical; Animals; Carcinoma, Squamous Cell; Female; Injections, Subcutaneous; Mesyla | 1987 |
DNA repair synthesis in fibroblast strains from patients with actinic keratosis, squamous cell carcinoma, basal cell carcinoma, or malignant melanoma after treatment with ultraviolet light, N-acetoxy-2-acetyl-aminofluorene, methyl methanesulfonate, and N-
Topics: Acetoxyacetylaminofluorene; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cells, Cultured; DNA Re | 1987 |