methyl methanesulfonate has been researched along with Carcinogenesis in 3 studies
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Assessing the shape of dose-response curves for DNA-damage in cellular systems and for the consequences of DNA damage in intact animals remains a controversial topic." | 2.53 | Approaches for characterizing threshold dose-response relationships for DNA-damage pathways involved in carcinogenicity in vivo and micronuclei formation in vitro. ( Andersen, ME; Clewell, RA, 2016) |
| "Studies on colon cancer have demonstrated that the depletion of E2F1 leads to reduced levels of homologous recombination (HR), resulting in interrupted DNA replication and the subsequent accumulation of DNA lesions." | 1.51 | E2F1 facilitates DNA break repair by localizing to break sites and enhancing the expression of homologous recombination factors. ( Choi, EH; Kim, KP, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, EH | 1 |
| Kim, KP | 1 |
| Stuckey, R | 1 |
| García-Rodríguez, N | 1 |
| Aguilera, A | 1 |
| Wellinger, RE | 1 |
| Clewell, RA | 1 |
| Andersen, ME | 1 |
1 review available for methyl methanesulfonate and Carcinogenesis
| Article | Year |
|---|---|
Approaches for characterizing threshold dose-response relationships for DNA-damage pathways involved in carcinogenicity in vivo and micronuclei formation in vitro.
Topics: Animals; Carcinogenesis; Cell Line; Computational Biology; DNA; DNA Damage; DNA Repair; Dose-Respons | 2016 |
2 other studies available for methyl methanesulfonate and Carcinogenesis
| Article | Year |
|---|---|
E2F1 facilitates DNA break repair by localizing to break sites and enhancing the expression of homologous recombination factors.
Topics: Carcinogenesis; Cell Division; Colonic Neoplasms; DNA Breaks, Double-Stranded; DNA Damage; DNA Repai | 2019 |
Role for RNA:DNA hybrids in origin-independent replication priming in a eukaryotic system.
Topics: Bacterial Proteins; Camptothecin; Carcinogenesis; Cell Cycle; Cell Separation; Chromosomes; DNA; DNA | 2015 |