methyl methanesulfonate has been researched along with Breast Neoplasms in 12 studies
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In MCF-7 breast cancer cells, MMTS induced movement of endogenous BRCA1 into distinctive nuclear foci that co-stained with the SSB repair protein XRCC1, but not the DSB repair protein gamma-H2AX." | 1.34 | Identification of sequences that target BRCA1 to nuclear foci following alkylative DNA damage. ( Au, WW; Henderson, BR, 2007) |
| "To evaluate its efficacy in sensitizing breast cancer cells to chemotherapy, MPG has been overexpressed in the breast cancer cell line, MDA-MB231." | 1.32 | Imbalancing the DNA base excision repair pathway in the mitochondria; targeting and overexpressing N-methylpurine DNA glycosylase in mitochondria leads to enhanced cell killing. ( Fishel, ML; Kelley, MR; Seo, YR; Smith, ML, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Lowder, LL | 1 |
| Powell, M | 1 |
| Miller, SE | 1 |
| Kishton, RJ | 1 |
| Kelly, CB | 1 |
| Cribb, CB | 1 |
| Mastro-Kishton, K | 1 |
| Chelvanambi, M | 1 |
| Do, PT | 1 |
| Govindapur, RR | 1 |
| Wardell, SE | 1 |
| McDonnell, DP | 1 |
| Bartolotti, LJ | 1 |
| Akkaraju, GR | 1 |
| Frampton, AR | 1 |
| Varadarajan, S | 1 |
| Harris, C | 1 |
| Savas, J | 1 |
| Ray, S | 1 |
| Shanle, EK | 1 |
| Hill, SJ | 1 |
| Clark, AP | 1 |
| Silver, DP | 1 |
| Livingston, DM | 1 |
| Chou, WC | 1 |
| Hu, LY | 1 |
| Hsiung, CN | 1 |
| Shen, CY | 1 |
| Fishel, ML | 1 |
| Seo, YR | 1 |
| Smith, ML | 3 |
| Kelley, MR | 2 |
| Rinne, M | 1 |
| Caldwell, D | 1 |
| Li, J | 1 |
| Zou, C | 1 |
| Bai, Y | 1 |
| Wazer, DE | 1 |
| Band, V | 1 |
| Gao, Q | 1 |
| Au, WW | 1 |
| Henderson, BR | 1 |
| Fan, S | 2 |
| Rivet, DJ | 1 |
| Duba, D | 1 |
| Zhan, Q | 2 |
| Kohn, KW | 1 |
| Fornace, AJ | 2 |
| O'Connor, PM | 2 |
| Bae, I | 1 |
| Yu, K | 1 |
| Alamo, I | 1 |
| Fujimori, A | 1 |
| Gupta, M | 1 |
| Hoki, Y | 1 |
| Pommier, Y | 1 |
| Chen, PL | 1 |
| Chen, CF | 1 |
| Chen, Y | 1 |
| Xiao, J | 1 |
| Sharp, ZD | 1 |
| Lee, WH | 1 |
12 other studies available for methyl methanesulfonate and Breast Neoplasms
| Article | Year |
|---|---|
Mechanistic Investigation of Site-specific DNA Methylating Agents Targeting Breast Cancer Cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; DNA Methylation; Drug Deli | 2021 |
Yeast-based screening of cancer mutations in the DNA damage response protein Mre11 demonstrates importance of conserved capping domain residues.
Topics: Adenocarcinoma; Breast Neoplasms; DNA Damage; DNA Repair; Early Detection of Cancer; Endodeoxyribonu | 2021 |
BRCA1 pathway function in basal-like breast cancer cells.
Topics: BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; DNA Breaks, Double-Stranded; DNA Replication; Fem | 2014 |
Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway.
Topics: Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; Cell Line; Checkpoint Kinase 2; DNA Damage | 2015 |
Imbalancing the DNA base excision repair pathway in the mitochondria; targeting and overexpressing N-methylpurine DNA glycosylase in mitochondria leads to enhanced cell killing.
Topics: Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Caspase 3; Caspases; Cel | 2003 |
Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells.
Topics: Adenoviridae; Alkylating Agents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Br | 2004 |
DSS1 is required for the stability of BRCA2.
Topics: Blotting, Western; BRCA2 Protein; Breast Neoplasms; DNA Damage; Female; Genomic Instability; Humans; | 2006 |
Identification of sequences that target BRCA1 to nuclear foci following alkylative DNA damage.
Topics: Alkylating Agents; Amino Acid Sequence; Ataxia Telangiectasia Mutated Proteins; BRCA1 Protein; Breas | 2007 |
Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline.
Topics: Apoptosis; Breast Neoplasms; Cell Line; Cell Survival; Cisplatin; Clone Cells; Doxorubicin; Etoposid | 1995 |
Abrogation of p53 function affects gadd gene responses to DNA base-damaging agents and starvation.
Topics: Animals; Breast Neoplasms; Carcinoma, Large Cell; CCAAT-Enhancer-Binding Proteins; Cell Cycle; Cell | 1996 |
Acquired camptothecin resistance of human breast cancer MCF-7/C4 cells with normal topoisomerase I and elevated DNA repair.
Topics: Breast Neoplasms; Camptothecin; Cell Cycle; DNA Damage; DNA Repair; DNA Topoisomerases, Type I; Drug | 1996 |
The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment.
Topics: BRCA2 Protein; Breast Neoplasms; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, Complementary; D | 1998 |