methyl methanesulfonate has been researched along with Amyotrophic Lateral Sclerosis in 3 studies
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Robison, SH | 3 |
| Tandan, R | 3 |
| Bradley, WG | 3 |
| Munzer, JS | 1 |
3 other studies available for methyl methanesulfonate and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Repair of N-methylpurines in DNA from lymphocytes of patients with amyotrophic lateral sclerosis.
Topics: Aged; Amyotrophic Lateral Sclerosis; Cell Survival; DNA; DNA Repair; Female; Humans; Male; Methyl Me | 1993 |
Deficient DNA repair in amyotrophic lateral sclerosis cells.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Cell Survival; Cells, Cultured; DNA; DNA Repair; Fibrobl | 1987 |
Deficient repair of alkylation damage of DNA in Alzheimer's disease and amyotrophic lateral sclerosis cells.
Topics: Alkylating Agents; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Cells, Cultured; DNA; DNA Damag | 1987 |