methyl methanesulfonate and Aging studies

methyl methanesulfonate and Aging

methyl methanesulfonate has been researched along with Aging in 13 studies

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

Excerpt	Relevance	Reference
" The effects of animal age, differences in strain and dosing regimen, and length of expression time were evaluated."	1.29	Induction of hepatic mutations in lacI transgenic mice. ( Hamner, RT; MacGregor, JT; Matthews, CD; Mirsalis, JC; O'Loughlin, KG; Provost, GS; Schindler, JE; Short, JM, 1993)

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (30.77)	18.7374
1990's	3 (23.08)	18.2507
2000's	6 (46.15)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

4 (30.77)

18.7374

1990's

3 (23.08)

18.2507

2000's

6 (46.15)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Shokolenko, I	1
Venediktova, N	1
Bochkareva, A	1
Wilson, GL	1
Alexeyev, MF	1
McColl, G	1
Vantipalli, MC	1
Lithgow, GJ	1
Hashimoto, K	1
Takasaki, W	1
Sato, I	1
Tsuda, S	1
Hall, JD	1
Almy, RE	1
Scherer, KL	1
Niedermüller, H	2
Mirsalis, JC	1
Provost, GS	1
Matthews, CD	1
Hamner, RT	1
Schindler, JE	1
O'Loughlin, KG	1
MacGregor, JT	1
Short, JM	1
Suh, Y	3
Park, SC	2
Lee, KA	1
Kim, WH	1
Han, BG	1
Vijg, J	1
Hirsch, GP	1
Holland, JM	1
Popp, RA	1
Bilbin, M	1
Tudek, B	1
Czeczot, H	1
Tilley, R	1
Miller, S	1
Srivastava, V	1
Busbee, D	1
Hofecker, G	1
Skalicky, M	1

Studies

Shokolenko, I

Venediktova, N

Bochkareva, A

Wilson, GL

Alexeyev, MF

McColl, G

Vantipalli, MC

Lithgow, GJ

Hashimoto, K

Takasaki, W

Sato, I

Tsuda, S

Hall, JD

Almy, RE

Scherer, KL

Niedermüller, H

Mirsalis, JC

Provost, GS

Matthews, CD

Hamner, RT

Schindler, JE

O'Loughlin, KG

MacGregor, JT

Short, JM

Suh, Y

Park, SC

Lee, KA

Kim, WH

Han, BG

Vijg, J

Hirsch, GP

Holland, JM

Popp, RA

Bilbin, M

Tudek, B

Czeczot, H

Tilley, R

Miller, S

Srivastava, V

Busbee, D

Hofecker, G

Skalicky, M

Other Studies

13 other studies available for methyl methanesulfonate and Aging

Article	Year
Oxidative stress induces degradation of mitochondrial DNA. Nucleic acids research, 2009, Volume: 37, Issue:8 Topics: Aged, 80 and over; Aging; Cell Line, Tumor; Cloning, Molecular; DNA Damage; DNA Repair; DNA, Mitocho	2009
The C. elegans ortholog of mammalian Ku70, interacts with insulin-like signaling to modulate stress resistance and life span. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:12 Topics: Aging; Animals; Antigens, Nuclear; Caenorhabditis elegans; Caenorhabditis elegans Proteins; DNA Repa	2005
DNA damage measured by comet assay and 8-OH-dG formation related to blood chemical analyses in aged rats. The Journal of toxicological sciences, 2007, Volume: 32, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Blood Chemical Analysis; Comet Assay; Deoxyguanosine; D	2007
DNA repair in cultured human fibroblasts does not decline with donor age. Experimental cell research, 1982, Volume: 139, Issue:2 Topics: Aged; Aging; Caffeine; Cell Line; Child, Preschool; DNA Repair; DNA, Viral; Fibroblasts; Humans; Inf	1982
Age dependency of DNA repair in rats after DNA damage by carcinogens. Mechanisms of ageing and development, 1982, Volume: 19, Issue:3 Topics: Aging; Animals; Carcinogens; Dimethylnitrosamine; DNA; DNA Repair; Male; Methyl Methanesulfonate; Me	1982
Induction of hepatic mutations in lacI transgenic mice. Mutagenesis, 1993, Volume: 8, Issue:3 Topics: Aging; Animals; Base Composition; beta-Galactosidase; Cell Division; Dimethylnitrosamine; DNA Repair	1993
Differential activation of mitogen-activated protein kinases by methyl methanesulfonate in the kidney of young and old rats. Mutation research, 2001, Oct-18, Volume: 497, Issue:1-2 Topics: Aging; Alkylating Agents; Animals; Carcinogens; DNA Damage; Enzyme Activation; Female; JNK Mitogen-A	2001
Age-specific changes in expression, activity, and activation of the c-Jun NH(2)-terminal kinase and p38 mitogen-activated protein kinases by methyl methanesulfonate in rats. Mechanisms of ageing and development, 2001, Volume: 122, Issue:15 Topics: Aging; Animals; Brain; Enzyme Activation; Female; JNK Mitogen-Activated Protein Kinases; Liver; Meth	2001
Aging alters the apoptotic response to genotoxic stress. Nature medicine, 2002, Volume: 8, Issue:1 Topics: Aging; Alkylation; Animals; Apoptosis; DNA Damage; Female; Injections, Intraperitoneal; Liver; Methy	2002
Amino acid analog incorporation into protein in dimethyl sulfoxide and mutagen-treated aging mice. Birth defects original article series, 1978, Volume: 14, Issue:1 Topics: Aging; Aminoisobutyric Acids; Animals; Dimethyl Sulfoxide; Female; Genetic Code; Hemoglobins; Leucin	1978
Induction of aberrant crypts in the colons of rats by alkylating agents. Acta biochimica Polonica, 1992, Volume: 39, Issue:1 Topics: 1,2-Dimethylhydrazine; Aging; Alkylating Agents; Animals; Carcinogens; Colonic Neoplasms; Dimethylhy	1992
Enhanced unscheduled DNA synthesis by secondary cultures of lung cells established from calorically restricted aged rats. Mechanisms of ageing and development, 1992, Volume: 63, Issue:2 Topics: Aging; Animals; Cells, Cultured; DNA; DNA Damage; DNA Repair; Fibroblasts; Food Deprivation; Lung; M	1992
Changes of DNA repair mechanisms during the aging of the rat. Mechanisms of ageing and development, 1985, Volume: 29, Issue:3 Topics: 4-Nitroquinoline-1-oxide; Aging; Animals; Biomechanical Phenomena; DNA; DNA Repair; DNA, Single-Stra	1985

Article

Year

Oxidative stress induces degradation of mitochondrial DNA.

Nucleic acids research, 2009, Volume: 37, Issue:8

Topics: Aged, 80 and over; Aging; Cell Line, Tumor; Cloning, Molecular; DNA Damage; DNA Repair; DNA, Mitocho

2009

The C. elegans ortholog of mammalian Ku70, interacts with insulin-like signaling to modulate stress resistance and life span.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:12

Topics: Aging; Animals; Antigens, Nuclear; Caenorhabditis elegans; Caenorhabditis elegans Proteins; DNA Repa

2005

DNA damage measured by comet assay and 8-OH-dG formation related to blood chemical analyses in aged rats.

The Journal of toxicological sciences, 2007, Volume: 32, Issue:3

Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Blood Chemical Analysis; Comet Assay; Deoxyguanosine; D

2007

DNA repair in cultured human fibroblasts does not decline with donor age.

Experimental cell research, 1982, Volume: 139, Issue:2

Topics: Aged; Aging; Caffeine; Cell Line; Child, Preschool; DNA Repair; DNA, Viral; Fibroblasts; Humans; Inf

1982

Age dependency of DNA repair in rats after DNA damage by carcinogens.

Mechanisms of ageing and development, 1982, Volume: 19, Issue:3

Topics: Aging; Animals; Carcinogens; Dimethylnitrosamine; DNA; DNA Repair; Male; Methyl Methanesulfonate; Me

1982

Induction of hepatic mutations in lacI transgenic mice.

Mutagenesis, 1993, Volume: 8, Issue:3

Topics: Aging; Animals; Base Composition; beta-Galactosidase; Cell Division; Dimethylnitrosamine; DNA Repair

1993

Differential activation of mitogen-activated protein kinases by methyl methanesulfonate in the kidney of young and old rats.

Mutation research, 2001, Oct-18, Volume: 497, Issue:1-2

Topics: Aging; Alkylating Agents; Animals; Carcinogens; DNA Damage; Enzyme Activation; Female; JNK Mitogen-A

2001

Age-specific changes in expression, activity, and activation of the c-Jun NH(2)-terminal kinase and p38 mitogen-activated protein kinases by methyl methanesulfonate in rats.

Mechanisms of ageing and development, 2001, Volume: 122, Issue:15

Topics: Aging; Animals; Brain; Enzyme Activation; Female; JNK Mitogen-Activated Protein Kinases; Liver; Meth

2001

Aging alters the apoptotic response to genotoxic stress.

Nature medicine, 2002, Volume: 8, Issue:1

Topics: Aging; Alkylation; Animals; Apoptosis; DNA Damage; Female; Injections, Intraperitoneal; Liver; Methy

2002

Amino acid analog incorporation into protein in dimethyl sulfoxide and mutagen-treated aging mice.

Birth defects original article series, 1978, Volume: 14, Issue:1

Topics: Aging; Aminoisobutyric Acids; Animals; Dimethyl Sulfoxide; Female; Genetic Code; Hemoglobins; Leucin

1978

Induction of aberrant crypts in the colons of rats by alkylating agents.

Acta biochimica Polonica, 1992, Volume: 39, Issue:1

Topics: 1,2-Dimethylhydrazine; Aging; Alkylating Agents; Animals; Carcinogens; Colonic Neoplasms; Dimethylhy

1992

Enhanced unscheduled DNA synthesis by secondary cultures of lung cells established from calorically restricted aged rats.

Mechanisms of ageing and development, 1992, Volume: 63, Issue:2

Topics: Aging; Animals; Cells, Cultured; DNA; DNA Damage; DNA Repair; Fibroblasts; Food Deprivation; Lung; M

1992

Changes of DNA repair mechanisms during the aging of the rat.

Mechanisms of ageing and development, 1985, Volume: 29, Issue:3

Topics: 4-Nitroquinoline-1-oxide; Aging; Animals; Biomechanical Phenomena; DNA; DNA Repair; DNA, Single-Stra

1985