methyl methanesulfonate has been researched along with Adult Premature Aging Syndrome in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "A defect in the Werner syndrome protein (WRN) leads to the premature aging disease Werner syndrome (WS)." | 1.32 | Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage. ( Bohr, VA; Cheng, WH; Dawut, L; Harrigan, JA; May, A; Opresko, PL; von Kobbe, C, 2003) |
| "Chromosomal aberrations were also synergistically increased in WRN(-/-)/BLM(-/-) cells when irradiated with UV light in late S to G(2) phases." | 1.31 | Werner and Bloom helicases are involved in DNA repair in a complementary fashion. ( Fujita, K; Furuichi, Y; Imamura, O; Itoh, C; Matsumoto, T; Takeda, S, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| von Kobbe, C | 1 |
| Harrigan, JA | 1 |
| May, A | 1 |
| Opresko, PL | 1 |
| Dawut, L | 1 |
| Cheng, WH | 1 |
| Bohr, VA | 1 |
| Dong, YP | 1 |
| Seki, M | 3 |
| Yoshimura, A | 1 |
| Inoue, E | 1 |
| Furukawa, S | 1 |
| Tada, S | 1 |
| Enomoto, T | 3 |
| Onoda, F | 2 |
| Miyajima, A | 2 |
| Ui, A | 1 |
| Satoh, Y | 1 |
| Imamura, O | 1 |
| Fujita, K | 1 |
| Itoh, C | 1 |
| Takeda, S | 1 |
| Furuichi, Y | 1 |
| Matsumoto, T | 1 |
5 other studies available for methyl methanesulfonate and Adult Premature Aging Syndrome
| Article | Year |
|---|---|
Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage.
Topics: Binding Sites; Cell Line; DNA Damage; DNA Helicases; DNA Repair; Exodeoxyribonucleases; Green Fluore | 2003 |
WRN functions in a RAD18-dependent damage avoidance pathway.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Cell Proliferation; Chickens; Cisplatin; DNA Damage; D | 2007 |
Elevation of sister chromatid exchange in Saccharomyces cerevisiae sgs1 disruptants and the relevance of the disruptants as a system to evaluate mutations in Bloom's syndrome gene.
Topics: Alleles; Bloom Syndrome; DNA Helicases; Dose-Response Relationship, Drug; Genetic Complementation Te | 2000 |
The N-terminal region of Sgs1, which interacts with Top3, is required for complementation of MMS sensitivity and suppression of hyper-recombination in sgs1 disruptants.
Topics: Amino Acid Sequence; Antineoplastic Agents, Alkylating; Bloom Syndrome; DNA Helicases; DNA Topoisome | 2001 |
Werner and Bloom helicases are involved in DNA repair in a complementary fashion.
Topics: 4-Nitroquinoline-1-oxide; Adenosine Triphosphatases; Amino Acid Sequence; Animals; B-Lymphocytes; Bl | 2002 |