Page last updated: 2024-10-31

methoxyflurane and Arrhythmia

methoxyflurane has been researched along with Arrhythmia in 25 studies

Methoxyflurane: An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with NITROUS OXIDE to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations Annual, 1994, p180)
methoxyflurane : An ether in which the two groups attached to the central oxygen atom are methyl and 2,2-dichloro-1,1-difluoroethyl.

Research Excerpts

ExcerptRelevanceReference
"The arrhythmogenic dosage of epinephrine, administered by constant intravenous infusion, was measured in five dogs during enflurane, methoxyflurane and halothane anaesthesia."5.25Doses of epinephrine causing arrhythmia during enflurane, methoxyflurane and halothane anaesthesia in dogs. ( Munson, ES; Tucker, WK, 1975)
"In 109 patients, it was determined that halothane, when used to anesthetize patients for oral surgical procedures, causes an increased risk of serious cardiac arrhythmias when compared to methoxyflurane and fentanyl/droperidol."3.65Aberrant conduction as a precursor to cardiac arrhythmias during anesthesia for oral surgery. ( Gotta, AW; Kangwalklai, SR; Kozam, R; Pelkofski, J; Sullivan, CA, 1976)
"The arrhythmogenic dosage of epinephrine, administered by constant intravenous infusion, was measured in five dogs during enflurane, methoxyflurane and halothane anaesthesia."1.25Doses of epinephrine causing arrhythmia during enflurane, methoxyflurane and halothane anaesthesia in dogs. ( Munson, ES; Tucker, WK, 1975)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199025 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DOBKIN, AB1
ISRAEL, JS1
ERICKSON, JC1
KRUMPERMAN, LW1
RONIS, ML1
Stephen, CR1
Black, GW1
Conway, CM1
Munson, ES1
Tucker, WK1
Puerto, BA1
Wong, KC1
Puerto, AX1
Tseng, CK1
Blatnick, RA1
Brown, ES1
Gotta, AW1
Sullivan, CA1
Pelkofski, J1
Kangwalklai, SR1
Kozam, R1
Yanagida, H1
Yamamura, H1
Kilmore, MA2
Clark, JP2
Holmes, JA1
Salo, M1
Laaksonen, V1
Short, CE1
Bingham, W1
Elliott, J1
Lyons, SM1
Estafanous, FG1
Viljoen, JF3
Loop, FD1
Woldorf, NM1
Pastore, PN1
Gindi, MY1
Meyer, R1
Allen, GD1
Hooley, JR1
Lewis, GB1
Reier, CE1
Hamelberg, W1
Burleigh, BW1
Greene, NM1
Reynolds, AK1
Chiz, JF1
Pasquet, AF1
Effler, DB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Determination of Analgesic Equipotent Doses of Inhaled Metoxyflurane vs. Intravenous Fentanyl Using Cold Pressor Test (CPT) in Volunteers: A Randomized, Double Blind, Placebo-controlled Crossover Study.[NCT03894800]Phase 412 participants (Actual)Interventional2019-04-23Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

25 other studies available for methoxyflurane and Arrhythmia

ArticleYear
The effect of SA 97, perphenazine, and hydroxyzine on epinephrine-induced cardiac arrhythmias during methoxyflurane anaesthesia in dogs.
    Canadian Anaesthetists' Society journal, 1962, Volume: 9

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Animals; Anti-Allergic Agents; Arrhythmias, Cardiac

1962
METHOXYFLURANE ANESTHESIA FOR MIDDLE EAR SURGERY.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1964, Volume: 80

    Topics: Adjuvants, Anesthesia; Anesthesia; Anesthesia, Endotracheal; Anesthetics; Arrhythmias, Cardiac; Ear,

1964
Clinical applications of methoxyflurane.
    Acta anaesthesiologica Scandinavica. Supplementum, 1966, Volume: 24

    Topics: Adjuvants, Anesthesia; Adolescent; Aged; Anesthesia, Inhalation; Anesthesia, Obstetrical; Animals; A

1966
A comparison of cardiac rhythm during halothane and methoxyflurane anaesthesia at normal and elevated levels of PaCO-2.
    Acta anaesthesiologica Scandinavica, 1967, Volume: 11, Issue:2

    Topics: Adolescent; Arrhythmias, Cardiac; Carbon Dioxide; Child; Electrocardiography; Female; Halothane; Hea

1967
Editorial: "Old lamps for new".
    British journal of anaesthesia, 1975, Volume: 47, Issue:8

    Topics: Anesthesia, Inhalation; Arrhythmias, Cardiac; Enflurane; Ethers; Halothane; Humans; Isoflurane; Kidn

1975
Doses of epinephrine causing arrhythmia during enflurane, methoxyflurane and halothane anaesthesia in dogs.
    Canadian Anaesthetists' Society journal, 1975, Volume: 22, Issue:4

    Topics: Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Blood Pressure; Carbon Dioxide; Dogs; Drug Sy

1975
Epinephrine-induced dysrhythmias: comparison during anaesthesia with narcotics and with halogenated inhalation agents in dogs.
    Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:4

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Arrhythmias, Cardiac; Blood Pressure; Dogs

1979
Anesthesia in pediatric otorhinolaryngology.
    Otolaryngologic clinics of North America, 1977, Volume: 10, Issue:1

    Topics: Anesthesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Arrhythmias, Cardiac; Child; Epinephrin

1977
Aberrant conduction as a precursor to cardiac arrhythmias during anesthesia for oral surgery.
    Journal of oral surgery (American Dental Association : 1965), 1976, Volume: 34, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, General; Arrhythmias, Cardiac; Child; Child

1976
Hidden factor of cardiac arrhythmia during light anesthesia.
    Acta anaesthesiologica Scandinavica, 1972, Volume: 16, Issue:1

    Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Electrocardiography; Elect

1972
Comparison of myocardial irritability of selected anesthetics.
    Research communications in chemical pathology and pharmacology, 1971, Volume: 2, Issue:6

    Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Blood Pressure; Carbon Dioxide; Chloroform; Cyclopropane

1971
Effect of ketamine on myocardial irritability.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:4

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardi

1974
The maintenance of the circulation during anaesthesia in patients with phaeochromocytoma.
    Annales chirurgiae et gynaecologiae Fenniae, 1972, Volume: 61, Issue:3

    Topics: Adolescent; Adult; Anesthesia, General; Anesthetics; Arrhythmias, Cardiac; Chlorprothixene; Female;

1972
Anesthetic complications.
    Modern veterinary practice, 1974, Volume: 55, Issue:8

    Topics: Acidosis; Alkalosis; Anesthesia, Inhalation; Anesthetics; Animals; Arrhythmias, Cardiac; Barbiturate

1974
Management of anaesthesia for phaeochromocytoma.
    Anaesthesia, 1972, Volume: 27, Issue:1

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Anesthesia, General; Arrhythmias, Cardiac; Blood Pressur

1972
Anaesthesia for ventricular aneurysmectomy.
    Canadian Anaesthetists' Society journal, 1972, Volume: 19, Issue:2

    Topics: Anesthesia, General; Arrhythmias, Cardiac; Blood Pressure; Blood Volume; Carbon Dioxide; Cardiac Out

1972
Extreme epinephrine sensitivity with a general anesthesia.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1972, Volume: 96, Issue:3

    Topics: Adult; Anesthesia, Inhalation; Arrhythmias, Cardiac; Blood Pressure; Child; Drug Hypersensitivity; D

1972
Anesthesia for coronary artery surgery.
    The Surgical clinics of North America, 1971, Volume: 51, Issue:5

    Topics: Anesthesia; Anesthesia, Endotracheal; Arrhythmias, Cardiac; Coronary Disease; Extracorporeal Circula

1971
Methoxyflurane in outpatient oral surgery.
    Oral surgery, oral medicine, and oral pathology, 1966, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Inhalation; Arrhythmias, Cardiac; Blood; Blood Pr

1966
Experimental observations on propranolol in anaesthesia.
    Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:6

    Topics: Acidosis; Animals; Arrhythmias, Cardiac; Dogs; Epinephrine; Ethyl Ethers; Halothane; Injections, Int

1969
Conscious analgesia and amnesia for cardioversion.
    JAMA, 1969, Dec-15, Volume: 210, Issue:11

    Topics: Adult; Amnesia; Analgesia; Arrhythmias, Cardiac; Consciousness; Electric Countershock; Female; Human

1969
Effect of methoxyflurane on epinephrine-induced ventricular arrhythmias.
    Canadian Anaesthetists' Society journal, 1970, Volume: 17, Issue:4

    Topics: Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Dogs; Electrocardiography; Epinephrine; Heart

1970
Halothane and methoxyflurane--a comparison of their effects on cardiac pacemaker fibers.
    Anesthesiology, 1970, Volume: 33, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Cats; Dogs; Epinephrine; Halothane; Heart Conduction System; Methoxyf

1970
Anaesthesia for internal mammary implant surgery.
    Anaesthesia, 1968, Volume: 23, Issue:4

    Topics: Anesthesia, General; Arrhythmias, Cardiac; Atropine; Cardiac Surgical Procedures; Humans; Hyperventi

1968
Anesthesia in revascularization surgery. A new advance.
    The Journal of thoracic and cardiovascular surgery, 1968, Volume: 56, Issue:2

    Topics: Analgesia; Anesthesia, Endotracheal; Anxiety; Arrhythmias, Cardiac; Coronary Vessels; Humans; Methox

1968