methoxyflurane has been researched along with Ache in 49 studies
Methoxyflurane: An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with NITROUS OXIDE to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations Annual, 1994, p180)
methoxyflurane : An ether in which the two groups attached to the central oxygen atom are methyl and 2,2-dichloro-1,1-difluoroethyl.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Self-administered methoxyflurane, also known as Penthrox, at a sub-anesthetic dose is a short-term, fast-acting, and safe analgesic that may provide suitable pain relief for cancer patients." | 10.79 | Literature review on the use of methoxyflurane in the management of pain in cancer-related procedures. ( Behroozian, T; Chow, E; Finkelstein, J; Finkelstein, S; Henry, P; Milton, L; Oliogu, E; Rivlin, L; Yee, A, 2023) |
| "To determine whether the addition of inhaled methoxyflurane to periprostatic infiltration of local anaesthetic (PILA) during transrectal ultrasonography-guided prostate biopsies (TRUSBs) improved pain and other aspects of the experience." | 9.51 | 'Pain-free TRUS B': a phase 3 double-blind placebo-controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasonography-guided prostate biopsy (ANZUP 1501). ( Buchan, N; Chalasani, V; Davis, ID; Espinoza, D; Ford, KS; Frydenberg, M; Gilling, P; Gordon, B; Grummet, J; Hawks, C; Hayne, D; Konstantatos, A; Martin, AJ; McCombie, SP; Nixon, A; O'Brien, C; Patel, MI; Sengupta, S; Shahbaz, S; Stockler, MR; Subramaniam, S; Williams, S; Woo, HH, 2022) |
| "Methoxyflurane inhaler (Penthrox) was low cost, rapid, feasible and easy to administer as a pain management strategy for Rezum therapy." | 8.12 | Efficacy and safety of methoxyflurane (Penthrox) for pain control during water vapor thermal therapy (Rezum) for benign prostatic enlargement. ( Bhojani, N; Chughtai, B; Elterman, DS; Zorn, KC, 2022) |
| "This study analysed the analgesic effect and changes in vital signs associated with administration of inhaled Methoxyflurane (MTX) and/or intranasal Fentanyl (INF) for prehospital management of visceral pain." | 7.77 | Inhaled methoxyflurane and intranasal fentanyl for prehospital management of visceral pain in an Australian ambulance service. ( Brightwell, R; Johnston, S; Thompson, JA; Wilkes, GJ; Ziman, M, 2011) |
| " doses of the full benzodiazepine inverse agonist beta-CCE immediately following cessation of exposure of rats to an anesthetic concentration of methoxyflurane significantly antagonized the duration of methoxyflurane anesthesia as measured by recovery of the righting reflex and/or pain sensitivity." | 7.67 | Antagonism of methoxyflurane-induced anesthesia in rats by benzodiazepine inverse agonists. ( Miller, DW; Tessel, RE; Yourick, DL, 1989) |
| "Self-administered methoxyflurane, also known as Penthrox, at a sub-anesthetic dose is a short-term, fast-acting, and safe analgesic that may provide suitable pain relief for cancer patients." | 6.79 | Literature review on the use of methoxyflurane in the management of pain in cancer-related procedures. ( Behroozian, T; Chow, E; Finkelstein, J; Finkelstein, S; Henry, P; Milton, L; Oliogu, E; Rivlin, L; Yee, A, 2023) |
| "4% of patients treated with MEOF had an adverse event (AE) compared with 4." | 6.79 | A randomised, double-blind, placebo-controlled study to assess the safety and efficacy of methoxyflurane for procedural pain of a bone marrow biopsy. ( Bressel, M; Milner, A; Spruyt, O; Wein, S; Westerman, D, 2014) |
| "Over a 12-month evaluation period, verbal numerical pain scores (VNPS) were gathered from adults with moderate to severe trauma pain attended by ambulance staff trained in administering and supplied with methoxyflurane." | 5.51 | Evaluation of the effectiveness and costs of inhaled methoxyflurane versus usual analgesia for prehospital injury and trauma: non-randomised clinical study. ( Rowan, E; Siriwardena, AN; Smith, MD; Spaight, R, 2022) |
| "To determine whether the addition of inhaled methoxyflurane to periprostatic infiltration of local anaesthetic (PILA) during transrectal ultrasonography-guided prostate biopsies (TRUSBs) improved pain and other aspects of the experience." | 5.51 | 'Pain-free TRUS B': a phase 3 double-blind placebo-controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasonography-guided prostate biopsy (ANZUP 1501). ( Buchan, N; Chalasani, V; Davis, ID; Espinoza, D; Ford, KS; Frydenberg, M; Gilling, P; Gordon, B; Grummet, J; Hawks, C; Hayne, D; Konstantatos, A; Martin, AJ; McCombie, SP; Nixon, A; O'Brien, C; Patel, MI; Sengupta, S; Shahbaz, S; Stockler, MR; Subramaniam, S; Williams, S; Woo, HH, 2022) |
| "Inhaled methoxyflurane for acute pain relief has demonstrated an analgesic effect superior to placebo." | 5.41 | Determination of equi-analgesic doses of inhaled methoxyflurane versus intravenous fentanyl using the cold pressor test in volunteers: a randomised, double-blinded, placebo-controlled crossover study. ( Comelon, M; Draegni, T; Høiseth, LØ; Lenz, H; Rosseland, LA, 2021) |
| "Pain is a common and significant feature of burn injury." | 5.40 | Inhaled methoxyflurane for pain and anxiety relief during burn wound care procedures: an Australian case series. ( Cleland, H; Mahar, PD; Menezes, H; Paul, E; Spinks, AB; Wasiak, J, 2014) |
| "The Methoxyflurane AnalGesia for Paediatric InjuriEs (MAGPIE) trial will provide efficacy and safety data for methoxyflurane administered via the Penthrox® inhaler, in children and adolescents who present to EDs with moderate to severe injury-related pain." | 5.30 | Inhaled methoxyflurane (Penthrox®) versus placebo for injury-associated analgesia in children-the MAGPIE trial (MEOF-002): study protocol for a randomised controlled trial. ( Barrett, MJ; Hartshorn, S; Irvine, AT; Lyttle, MD; Yee, SA, 2019) |
| "Methoxyflurane (MTX) is an inhalation agent that has several potential benefits for limiting various types of pain in ambulance care." | 4.31 | Ambulance nurses' experiences of pain management with Penthrox® in Swedish ambulance care: A mixed method study. ( Ivarsson, B; Johansson, A; Svensson, A; Wihlborg, J, 2023) |
| "In prehospital use, inhaled methoxyflurane as sole analgesic is effective for transport of trauma patients (62%) with moderate to severe pain." | 4.12 | Usability and effectiveness of inhaled methoxyflurane for prehospital analgesia - a prospective, observational study. ( Doppler, R; Egger, A; Pimiskern, M; Trimmel, H; Voelckel, WG, 2022) |
| "Methoxyflurane is commonly used by ambulance services to treat pain in pregnant women in WA." | 4.12 | Prevalence and Perinatal Outcomes Following In Utero Exposure to Prehospital Emergency Methoxyflurane: A 17-Year Retrospective Cohort Study. ( Kelty, E; Murray, K; Preen, D; Pyle, A; Sanfilippo, F, 2022) |
| "Methoxyflurane inhaler (Penthrox) was low cost, rapid, feasible and easy to administer as a pain management strategy for Rezum therapy." | 4.12 | Efficacy and safety of methoxyflurane (Penthrox) for pain control during water vapor thermal therapy (Rezum) for benign prostatic enlargement. ( Bhojani, N; Chughtai, B; Elterman, DS; Zorn, KC, 2022) |
| "This study analysed the analgesic effect and changes in vital signs associated with administration of inhaled Methoxyflurane (MTX) and/or intranasal Fentanyl (INF) for prehospital management of visceral pain." | 3.77 | Inhaled methoxyflurane and intranasal fentanyl for prehospital management of visceral pain in an Australian ambulance service. ( Brightwell, R; Johnston, S; Thompson, JA; Wilkes, GJ; Ziman, M, 2011) |
| " doses of the full benzodiazepine inverse agonist beta-CCE immediately following cessation of exposure of rats to an anesthetic concentration of methoxyflurane significantly antagonized the duration of methoxyflurane anesthesia as measured by recovery of the righting reflex and/or pain sensitivity." | 3.67 | Antagonism of methoxyflurane-induced anesthesia in rats by benzodiazepine inverse agonists. ( Miller, DW; Tessel, RE; Yourick, DL, 1989) |
| "4% of patients treated with MEOF had an adverse event (AE) compared with 4." | 2.79 | A randomised, double-blind, placebo-controlled study to assess the safety and efficacy of methoxyflurane for procedural pain of a bone marrow biopsy. ( Bressel, M; Milner, A; Spruyt, O; Wein, S; Westerman, D, 2014) |
| "Methoxyflurane was developed as an anaesthetic agent and introduced into clinical practice in 1960." | 2.53 | Methoxyflurane: a review with emphasis on its role in dental practice. ( Bonanno, C; Kingon, A; McCullough, M; Sambrook, P; Yap, T, 2016) |
| "This article reviews the evidence for the analgesic efficacy of methoxyflurane in both prehospital and ED settings, as well as the adverse event profile associated with methoxyflurane use." | 2.45 | Review article: Efficacy and safety of methoxyflurane analgesia in the emergency department and prehospital setting. ( Babl, FE; Grindlay, J, 2009) |
| "Methoxyflurane is a fluorinated hydrocarbon gas which has analgesic properties when inhaled." | 1.62 | Inhaled methoxyflurane (Penthrox) for analgesia in trauma: a systematic review protocol. ( Eager, MM; Nolan, GS; Ramjeeawon, A; Taylor, N; Tonks, K, 2021) |
| "Nitrous oxide was available for the first 5 months studied, followed by 6 months methoxyflurane availability." | 1.62 | Frequency and duration of ambulance officer exposure to nitrous oxide and methoxyflurane in New Zealand. ( Allison, SJ; Chase, JG; Docherty, PD; Pons, D, 2021) |
| "Methoxyflurane was an inhaled agent commonly used for general anesthesia in the 1960s, but its clinical role gradually decreased in the 1970s because of reports of dose-dependent nephrotoxicity." | 1.56 | The Reincarnation of Methoxyflurane. ( Ikeda, S, 2020) |
| "Methoxyflurane is an inhalation analgesic used in the emergency department (ED) but also has minimal sedative properties." | 1.51 | Inhaled methoxyflurane for the reduction of acute anterior shoulder dislocation in the emergency department. ( Blom, CJ; Kelliher, JH; McNicholl, B; Umana, E, 2019) |
| "Pain is a common and significant feature of burn injury." | 1.40 | Inhaled methoxyflurane for pain and anxiety relief during burn wound care procedures: an Australian case series. ( Cleland, H; Mahar, PD; Menezes, H; Paul, E; Spinks, AB; Wasiak, J, 2014) |
| "Methoxyflurane was mainly used for extremity injuries (82%)." | 1.33 | Inhaled methoxyflurane as a prehospital analgesic in children. ( Babl, FE; Bernard, S; Jamison, SR; Spicer, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (38.78) | 18.7374 |
| 1990's | 2 (4.08) | 18.2507 |
| 2000's | 3 (6.12) | 29.6817 |
| 2010's | 10 (20.41) | 24.3611 |
| 2020's | 15 (30.61) | 2.80 |
| Authors | Studies |
|---|---|
| Trimmel, H | 1 |
| Egger, A | 1 |
| Doppler, R | 1 |
| Pimiskern, M | 1 |
| Voelckel, WG | 1 |
| Smith, MD | 1 |
| Rowan, E | 1 |
| Spaight, R | 1 |
| Siriwardena, AN | 1 |
| Pyle, A | 1 |
| Kelty, E | 1 |
| Sanfilippo, F | 1 |
| Murray, K | 1 |
| Preen, D | 1 |
| Elterman, DS | 2 |
| Zorn, KC | 2 |
| Bhojani, N | 2 |
| Chughtai, B | 2 |
| Du, A | 1 |
| Hannan, L | 1 |
| Muruganandan, S | 1 |
| Finkelstein, S | 1 |
| Oliogu, E | 1 |
| Yee, A | 1 |
| Milton, L | 1 |
| Rivlin, L | 1 |
| Henry, P | 1 |
| Behroozian, T | 1 |
| Chow, E | 1 |
| Finkelstein, J | 1 |
| Wihlborg, J | 1 |
| Svensson, A | 1 |
| Ivarsson, B | 1 |
| Johansson, A | 1 |
| Montassier, E | 1 |
| Freund, Y | 1 |
| Borobia, AM | 1 |
| Carcas Sansuán, AJ | 1 |
| Ikeda, S | 1 |
| Eager, MM | 1 |
| Nolan, GS | 1 |
| Tonks, K | 1 |
| Ramjeeawon, A | 1 |
| Taylor, N | 1 |
| Lenz, H | 1 |
| Høiseth, LØ | 1 |
| Comelon, M | 1 |
| Draegni, T | 1 |
| Rosseland, LA | 1 |
| Bond, C | 1 |
| Westafer, L | 1 |
| Challen, K | 1 |
| Milne, WK | 1 |
| Hayne, D | 1 |
| Grummet, J | 1 |
| Espinoza, D | 1 |
| McCombie, SP | 1 |
| Chalasani, V | 1 |
| Ford, KS | 1 |
| Frydenberg, M | 1 |
| Gilling, P | 1 |
| Gordon, B | 1 |
| Hawks, C | 1 |
| Konstantatos, A | 1 |
| Martin, AJ | 1 |
| Nixon, A | 1 |
| O'Brien, C | 1 |
| Patel, MI | 1 |
| Sengupta, S | 1 |
| Shahbaz, S | 1 |
| Subramaniam, S | 1 |
| Williams, S | 1 |
| Woo, HH | 1 |
| Stockler, MR | 1 |
| Davis, ID | 1 |
| Buchan, N | 1 |
| Allison, SJ | 1 |
| Docherty, PD | 1 |
| Pons, D | 1 |
| Chase, JG | 1 |
| Umana, E | 1 |
| Kelliher, JH | 1 |
| Blom, CJ | 1 |
| McNicholl, B | 1 |
| Hartshorn, S | 1 |
| Barrett, MJ | 1 |
| Lyttle, MD | 1 |
| Yee, SA | 1 |
| Irvine, AT | 1 |
| Spruyt, O | 1 |
| Westerman, D | 1 |
| Milner, A | 1 |
| Bressel, M | 1 |
| Wein, S | 1 |
| Carley, S | 1 |
| Body, R | 1 |
| Kingon, A | 1 |
| Yap, T | 1 |
| Bonanno, C | 1 |
| Sambrook, P | 1 |
| McCullough, M | 1 |
| Gaskell, AL | 1 |
| Jephcott, CG | 1 |
| Smithells, JR | 1 |
| Sleigh, JW | 1 |
| Blair, HA | 1 |
| Frampton, JE | 1 |
| Grindlay, J | 1 |
| Babl, FE | 2 |
| Johnston, S | 1 |
| Wilkes, GJ | 1 |
| Thompson, JA | 1 |
| Ziman, M | 1 |
| Brightwell, R | 1 |
| Boĭko, VV | 1 |
| Sushkov, SV | 1 |
| Zamiatin, PN | 1 |
| Krut'ko, EN | 1 |
| Wasiak, J | 1 |
| Mahar, PD | 1 |
| Paul, E | 1 |
| Menezes, H | 1 |
| Spinks, AB | 1 |
| Cleland, H | 1 |
| POWER, DJ | 1 |
| WYANT, GM | 1 |
| CHANG, CA | 1 |
| RAPICAVOLI, E | 1 |
| LAMBIE, RS | 1 |
| HUDON, F | 1 |
| KAVENEY, RE | 1 |
| WASMUTH, CE | 1 |
| Jamison, SR | 1 |
| Spicer, M | 1 |
| Bernard, S | 1 |
| Babl, F | 1 |
| Barnett, P | 1 |
| Palmer, G | 1 |
| Oakley, E | 1 |
| Davidson, A | 1 |
| Dimitrov, A | 1 |
| Iordanov, K | 1 |
| Tomi, K | 1 |
| Mashimo, T | 1 |
| Tashiro, C | 1 |
| Yagi, M | 1 |
| Pak, M | 1 |
| Nishimura, S | 1 |
| Nishimura, M | 1 |
| Yoshiya, I | 1 |
| Pogorelko, AG | 1 |
| Aleksandrin, AG | 1 |
| Baindurashvili, AG | 1 |
| Pakhomova, EA | 1 |
| Ladipo, OA | 1 |
| Adelusi, B | 1 |
| Areso, MP | 1 |
| Frazer, A | 1 |
| Miller, DW | 1 |
| Yourick, DL | 1 |
| Tessel, RE | 1 |
| Ackermann, U | 1 |
| Beckmann, W | 1 |
| Foitzik, H | 1 |
| Lawin, P | 1 |
| Crawford, JS | 1 |
| Endo, M | 1 |
| Iizumi, K | 1 |
| Isshiki, J | 1 |
| Ito, K | 1 |
| Muto, Y | 1 |
| Payne, JP | 1 |
| Bergsjo, P | 1 |
| Lindbaek, E | 1 |
| Ferrari, HA | 1 |
| Fuson, RL | 1 |
| Dent, SJ | 1 |
| Oyama, T | 1 |
| Maeda, C | 1 |
| Kimura, H | 1 |
| Tanaka, R | 1 |
| Watanabe, T | 1 |
| Noguchi, I | 1 |
| Mekari, K | 1 |
| Parkhouse, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Determination of Analgesic Equipotent Doses of Inhaled Metoxyflurane vs. Intravenous Fentanyl Using Cold Pressor Test (CPT) in Volunteers: A Randomized, Double Blind, Placebo-controlled Crossover Study.[NCT03894800] | Phase 4 | 12 participants (Actual) | Interventional | 2019-04-23 | Completed | ||
| A Randomised, Double-blind, Multicentre, Placebo Controlled Study to Evaluate the Safety and Efficacy of Methoxyflurane (PENTHROX®) for the Treatment of Acute Pain in Children and Adolescents From 6 to Less Than 18 Years of Age (Presenting to an Emergency[NCT03215056] | Phase 3 | 222 participants (Anticipated) | Interventional | 2017-06-30 | Recruiting | ||
| A Phase IV, Randomized, Double Blind, Single Centre, Placebo Controlled Study to Assess the Safety and Efficacy of Methoxyflurane [Penthrox] for the Treatment of Incident Pain in Participants Undergoing a Bone Marrow Biopsy Procedure[NCT00524927] | Phase 4 | 110 participants (Anticipated) | Interventional | 2007-09-30 | Completed | ||
| Efficacy and Safety of Methoxyflurane Vaporized (PENTHROX®) in the Treatment of Acute Trauma Pain in Pre-hospital Setting and in the Emergency Department in Italy: a Multicentre, Randomized, Controlled, Open-label Study[NCT03585374] | Phase 3 | 272 participants (Actual) | Interventional | 2018-02-08 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for methoxyflurane and Ache
| Article | Year |
|---|---|
A narrative review on pain control interventions for non-surgical pleural procedures.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Methoxyflurane; Pain; Pain Management; Quality of L | 2023 |
Literature review on the use of methoxyflurane in the management of pain in cancer-related procedures.
Topics: Anesthetics, Inhalation; Cancer Pain; Humans; Male; Methoxyflurane; Neoplasms; Observational Studies | 2023 |
Methoxyflurane: a review with emphasis on its role in dental practice.
Topics: Anesthesia; Anesthetics, Inhalation; Dentistry; Humans; Hypnotics and Sedatives; Methoxyflurane; Pai | 2016 |
Methoxyflurane: A Review in Trauma Pain.
Topics: Adult; Anesthetics, Inhalation; Emergency Service, Hospital; Humans; Methoxyflurane; Nebulizers and | 2016 |
Review article: Efficacy and safety of methoxyflurane analgesia in the emergency department and prehospital setting.
Topics: Adult; Analgesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Chemical and Drug Induced Liver I | 2009 |
Review article: Efficacy and safety of methoxyflurane analgesia in the emergency department and prehospital setting.
Topics: Adult; Analgesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Chemical and Drug Induced Liver I | 2009 |
Review article: Efficacy and safety of methoxyflurane analgesia in the emergency department and prehospital setting.
Topics: Adult; Analgesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Chemical and Drug Induced Liver I | 2009 |
Review article: Efficacy and safety of methoxyflurane analgesia in the emergency department and prehospital setting.
Topics: Adult; Analgesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Chemical and Drug Induced Liver I | 2009 |
Advances in anaesthesia.
Topics: Analgesics; Anesthesia; Anesthesia, General; Anesthesia, Intravenous; Body Fluids; Halothane; Humans | 1968 |
9 trials available for methoxyflurane and Ache
| Article | Year |
|---|---|
Evaluation of the effectiveness and costs of inhaled methoxyflurane versus usual analgesia for prehospital injury and trauma: non-randomised clinical study.
Topics: Acetaminophen; Administration, Inhalation; Adult; Ambulances; Analgesia; Analgesics; Anesthetics, In | 2022 |
Literature review on the use of methoxyflurane in the management of pain in cancer-related procedures.
Topics: Anesthetics, Inhalation; Cancer Pain; Humans; Male; Methoxyflurane; Neoplasms; Observational Studies | 2023 |
Determination of equi-analgesic doses of inhaled methoxyflurane versus intravenous fentanyl using the cold pressor test in volunteers: a randomised, double-blinded, placebo-controlled crossover study.
Topics: Administration, Inhalation; Administration, Intravenous; Adult; Analgesics, Opioid; Anesthetics, Inh | 2021 |
'Pain-free TRUS B': a phase 3 double-blind placebo-controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasonography-guided prostate biopsy (ANZUP 1501).
Topics: Anesthesia, Local; Anesthetics, Local; Biopsy; Humans; Lidocaine; Male; Methoxyflurane; Pain; Pain M | 2022 |
Inhaled methoxyflurane (Penthrox®) versus placebo for injury-associated analgesia in children-the MAGPIE trial (MEOF-002): study protocol for a randomised controlled trial.
Topics: Administration, Inhalation; Adolescent; Age Factors; Analgesics; Child; Clinical Trials, Phase III a | 2019 |
A randomised, double-blind, placebo-controlled study to assess the safety and efficacy of methoxyflurane for procedural pain of a bone marrow biopsy.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Australia; Biopsy; Bone Marrow; Bone Marro | 2014 |
Self-administered methoxyflurane for procedural analgesia: experience in a tertiary Australasian centre.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlle | 2016 |
A pilot study of inhaled methoxyflurane for procedural analgesia in children.
Topics: Adolescent; Analgesia, Patient-Controlled; Anesthesia, Inhalation; Anesthetics, Inhalation; Australi | 2007 |
Comparison between nitrous oxide and methoxyflurane for obstetrical analgesia.
Topics: Adult; Anesthesia, Obstetrical; Apgar Score; Clinical Trials as Topic; Female; Humans; Labor, Obstet | 1971 |
35 other studies available for methoxyflurane and Ache
| Article | Year |
|---|---|
Usability and effectiveness of inhaled methoxyflurane for prehospital analgesia - a prospective, observational study.
Topics: Adult; Analgesia; Analgesics; Anesthetics, Inhalation; Emergency Medical Services; Humans; Methoxyfl | 2022 |
Prevalence and Perinatal Outcomes Following In Utero Exposure to Prehospital Emergency Methoxyflurane: A 17-Year Retrospective Cohort Study.
Topics: Emergency Medical Services; Female; Fentanyl; Humans; Infant, Newborn; Methoxyflurane; Pain; Pregnan | 2022 |
Efficacy and safety of methoxyflurane (Penthrox) for pain control during water vapor thermal therapy (Rezum) for benign prostatic enlargement.
Topics: Anesthetics, Inhalation; Humans; Male; Methoxyflurane; Pain; Pain Management; Prostatic Hyperplasia; | 2022 |
Efficacy and safety of methoxyflurane (Penthrox) for pain control during water vapor thermal therapy (Rezum) for benign prostatic enlargement.
Topics: Anesthetics, Inhalation; Humans; Male; Methoxyflurane; Pain; Pain Management; Prostatic Hyperplasia; | 2022 |
Efficacy and safety of methoxyflurane (Penthrox) for pain control during water vapor thermal therapy (Rezum) for benign prostatic enlargement.
Topics: Anesthetics, Inhalation; Humans; Male; Methoxyflurane; Pain; Pain Management; Prostatic Hyperplasia; | 2022 |
Efficacy and safety of methoxyflurane (Penthrox) for pain control during water vapor thermal therapy (Rezum) for benign prostatic enlargement.
Topics: Anesthetics, Inhalation; Humans; Male; Methoxyflurane; Pain; Pain Management; Prostatic Hyperplasia; | 2022 |
Ambulance nurses' experiences of pain management with Penthrox® in Swedish ambulance care: A mixed method study.
Topics: Ambulances; Cross-Sectional Studies; Humans; Methoxyflurane; Nurses; Pain; Pain Management; Sweden | 2023 |
Methoxyflurane May Provide Faster Relief Than Suboptimal Treatment, but Not Better.
Topics: Analgesia; Emergency Service, Hospital; Humans; Methoxyflurane; Pain; Pain Management | 2020 |
In reply.
Topics: Analgesia; Emergency Service, Hospital; Humans; Methoxyflurane; Pain; Pain Management | 2020 |
The Reincarnation of Methoxyflurane.
Topics: Administration, Inhalation; Analgesics; Anesthetics, Inhalation; Conscious Sedation; Contraindicatio | 2020 |
Inhaled methoxyflurane (Penthrox) for analgesia in trauma: a systematic review protocol.
Topics: Analgesia; Anesthetics, Inhalation; Europe; Humans; Meta-Analysis as Topic; Methoxyflurane; Pain; Pa | 2021 |
Hot off the press: the RAMPED trial-methoxyflurane for analgesia in the emergency department.
Topics: Analgesia; Emergency Service, Hospital; Humans; Methoxyflurane; Pain; Pain Management | 2021 |
Frequency and duration of ambulance officer exposure to nitrous oxide and methoxyflurane in New Zealand.
Topics: Air Pollutants, Occupational; Ambulances; Anesthetics, Inhalation; Health Personnel; Humans; Inhalat | 2021 |
Inhaled methoxyflurane for the reduction of acute anterior shoulder dislocation in the emergency department.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Emergency Service | 2019 |
Methoxyflurane is a better painkiller than placebo: but do we want to know more?
Topics: Acute Disease; Analgesia; Anesthetics, Inhalation; Humans; Methoxyflurane; Pain; Placebos; Randomize | 2014 |
Inhaled methoxyflurane and intranasal fentanyl for prehospital management of visceral pain in an Australian ambulance service.
Topics: Administration, Inhalation; Administration, Intranasal; Adolescent; Adult; Aged; Ambulances; Analges | 2011 |
[Application of penthrox preparation in patients with traumatic disease].
Topics: Administration, Inhalation; Analgesics; Humans; Methoxyflurane; Pain; Pain Measurement; Treatment Ou | 2011 |
Inhaled methoxyflurane for pain and anxiety relief during burn wound care procedures: an Australian case series.
Topics: Administration, Inhalation; Adult; Ambulatory Care; Anesthetics, Inhalation; Anxiety; Burns; Female; | 2014 |
McGill University experiences with methoxyflurane.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Ethers; Methoxyflurane; Pain; Pain Management; Univ | 1961 |
Methoxyflurane (penthrane): a laboratory and clinical study.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Ethers; Methoxyflurane; Pain; Pain Management | 1961 |
THE ANALGESIA OF METHOXYFLURANE.
Topics: Analgesia; Anesthetics; Humans; Methoxyflurane; Pain; Pain Management | 1963 |
Methoxyflurane.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Ethers; Methoxyflurane; Pain; Pain Management | 1961 |
Methoxyflurane: a clinical evaluation of its effects, based on five hundred cases.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Ethers; Methoxyflurane; Pain; Pain Management | 1962 |
Inhaled methoxyflurane as a prehospital analgesic in children.
Topics: Administration, Inhalation; Adolescent; Anesthetics, Inhalation; Child; Child, Preschool; Conscious | 2006 |
[Reaction to pain and wakefulness in anesthesia for cesarean section].
Topics: Anesthesia, Obstetrical; Cesarean Section; Female; Humans; Methoxyflurane; Nitrous Oxide; Pain; Prea | 1982 |
Alterations in pain threshold and psychomotor response associated with subanaesthetic concentrations of inhalation anaesthetics in humans.
Topics: Adult; Anesthesia, Inhalation; Anesthetics; Enflurane; Ethers; Halothane; Humans; Isoflurane; Male; | 1993 |
[Methoxyflurane analgesia].
Topics: Burns; Female; Humans; Male; Methoxyflurane; Pain; Pain, Postoperative; Self Administration | 1979 |
[Use of subnarcotic concentrations of methoxyflurane in children with burns].
Topics: Adolescent; Analgesia; Anesthesia, Inhalation; Bandages; Burns; Child; Child, Preschool; Humans; Met | 1976 |
Pain relief in labour using methoxyflurane.
Topics: Adult; Anesthesia, Obstetrical; Female; Humans; Labor, Obstetric; Methoxyflurane; Pain; Pregnancy | 1976 |
Effect of repeated administration of novel stressors on central beta adrenoceptors.
Topics: Adrenergic beta-Antagonists; Animals; Brain Chemistry; Cold Temperature; Electroshock; Immobilizatio | 1991 |
Antagonism of methoxyflurane-induced anesthesia in rats by benzodiazepine inverse agonists.
Topics: Anesthesia; Animals; Azides; Benzodiazepines; Carbolines; Electric Stimulation; Ketamine; Male; Meth | 1989 |
[Analgesia with methoxyflurane].
Topics: Anesthesia, Obstetrical; Atropine; Female; Humans; Labor, Obstetric; Methoxyflurane; Nausea; Obstetr | 1971 |
Analgesia and anaesthesia in labour.
Topics: Analgesia; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Obstetrical; Cesarean Section; Fem | 1974 |
[Postoperative pain relief with the penthrane analgizer].
Topics: Analgesics; Humans; Methods; Methoxyflurane; Pain; Postoperative Complications | 1973 |
The relationship of the anesthetic agent to postoperative analgesic requirements.
Topics: Aged; Anesthesia; Aortic Aneurysm; Cyclopropanes; Ethyl Ethers; Female; Fentanyl; Halothane; Humans; | 1969 |
[Effect of methoxyflurane analgesia by an analgizer on pain-threshold, EEG, arterial methoxyflurane concentration and blood gases].
Topics: Adolescent; Adult; Analgesia; Anesthesia, Dental; Arteries; Carbon Dioxide; Child; Electroencephalog | 1969 |
[Effect of methoxyflurane inhalation using the Analgizer on acids-base balance during pain relief].
Topics: Acid-Base Equilibrium; Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Male; Metho | 1970 |
Inhalation anaesthesia and analgesia.
Topics: Abnormalities, Drug-Induced; Analgesia; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthesiol | 1967 |