methoxychlor has been researched along with Pregnancy in 57 studies
Methoxychlor: An insecticide. Methoxychlor has estrogenic effects in mammals, among other effects.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of Methoxychlor (MXC) on the thymus was examined in rat pups that were delivered from dams receiving MXC at a dietary concentration of 0 or 1500 ppm for a period from pregnancy to lactation." | 7.71 | Thymic atrophy induced by methoxychlor in rat pups. ( Fujisawa, H; Harada, T; Hayashi, K; Kosaka, T; Maita, K; Takeda, M; Takeuchi, Y; Teramoto, S; Yoshida, T, 2002) |
| " To address the short-term effects of MXC on fertility, the differential effects of MXC dosage and timing of administration (relative to implantation) on several gestational parameters were investigated." | 5.28 | Antifertility effect of methoxychlor in female rats: dose- and time-dependent blockade of pregnancy. ( Cummings, AM; Gray, LE, 1989) |
| "The effect of Methoxychlor (MXC) on the thymus was examined in rat pups that were delivered from dams receiving MXC at a dietary concentration of 0 or 1500 ppm for a period from pregnancy to lactation." | 3.71 | Thymic atrophy induced by methoxychlor in rat pups. ( Fujisawa, H; Harada, T; Hayashi, K; Kosaka, T; Maita, K; Takeda, M; Takeuchi, Y; Teramoto, S; Yoshida, T, 2002) |
| "This study was designed to assess whether exposure to the estrogenic pesticide methoxychlor (MXC) during pregnancy would affect reproductive parameters not only in female offspring exposed prenatally, but also in those of a subsequent litter." | 3.68 | Effects of methoxychlor treatment of pregnant mice on female offspring of the treated and subsequent pregnancies. ( Corkern, M; Swartz, WJ, 1992) |
| "Methoxychlor is an organochlorine pesticide having a weak estrogenicity, which is estimated to be approximately 1000- to 14,000-fold less potent to a natural ligand, 17β-estradiol." | 2.50 | Reproductive toxicities of methoxychlor based on estrogenic properties of the compound and its estrogenic metabolite, hydroxyphenyltrichloroethane. ( Aoyama, H; Chapin, RE, 2014) |
| "Methoxychlor (MXC) is a synthetic estrogen known as a persistent organochlorine and used as a pesticide." | 1.40 | Fetal and neonatal exposure to the endocrine disruptor, methoxychlor, reduces lean body mass and bone mineral density and increases cortical porosity. ( Buckendahl, P; Dunn, MG; Fagnant, HS; Shapses, SA; Shupper, P; Uzumcu, M, 2014) |
| "Methoxychlor (MXC) is an organochlorine pesticide with estrogenic, anti-estrogenic, and anti-androgenic properties." | 1.35 | Developmental methoxychlor exposure affects multiple reproductive parameters and ovarian folliculogenesis and gene expression in adult rats. ( Armenti, AE; Passantino, L; Uzumcu, M; Zama, AM, 2008) |
| "Methoxychlor has been shown to be estrogenic in both in vivo and in vitro studies." | 1.33 | Dietary methoxychlor exposure modulates splenic natural killer cell activity, antibody-forming cell response and phenotypic marker expression in F0 and F1 generations of Sprague Dawley rats. ( Booker, CD; Delclos, KB; Germolec, DR; Guo, TL; Hernendez, DM; McCay, JA; Newbold, RR; Weis, C; White, KL, 2005) |
| "Methoxychlor is an insecticide with estrogen-like activity, thus exposure during development might cause sexually dimorphic behavioral alterations." | 1.33 | Long term dietary methoxychlor exposure in rats increases sodium solution consumption but has few effects on other sexually dimorphic behaviors. ( Delclos, KB; Ferguson, SA; Flynn, KM; Newbold, RR, 2005) |
| "Genistein (GE) is a prevalent phytoestrogen whose presence in human and animal foods may affect biological actions of synthetic endocrine active compounds." | 1.33 | Altered mammary gland development in male rats exposed to genistein and methoxychlor. ( Bartolucci-Page, E; Fenton, SE; Wang, XJ; You, L, 2006) |
| "We previously performed dose-response studies of genistein, diisononyl phthalate, 4-nonylphenol, methoxychlor (MXC), and bisphenol A to examine the impact of maternal dietary exposure from gestational day 15 to postnatal day 10 on the development of rat reproductive system in later life." | 1.32 | Alteration of pituitary hormone-immunoreactive cell populations in rat offspring after maternal dietary exposure to endocrine-active chemicals. ( Hirose, M; Lee, KY; Masutomi, N; Shibutani, M; Takagi, H; Uneyama, C, 2004) |
| "Methoxychlor (MXC) is a non-steroidal pesticide that is known to possess estrogenic activity, and therefore may be potentially hazardous to the development and/or reproduction." | 1.32 | Effects of methoxychlor exposure during perinatal period on reproductive function after maturation in rats. ( Chiba, S; Lee, HC; Nishihara, M; Suzuki, M; Yonezawa, T, 2004) |
| " We thus found opposite effects of fetal exposure to a low and a high dose of DES on the uterine response to estradiol (inverted-U dose-response relationship)." | 1.31 | Uterine responsiveness to estradiol and DNA methylation are altered by fetal exposure to diethylstilbestrol and methoxychlor in CD-1 mice: effects of low versus high doses. ( Alworth, LC; Besch-Williford, CL; Day, JK; Howdeshell, KL; Huang, TH; Lubahn, DB; Ruhlen, RL; vom Saal, FS, 2002) |
| " In vivo studies indicated that the 3-day uterotrophic assay in prepubertal rats was the best method for detecting estrogenic activity when compared with all other end points, based upon the dose-response data for ethynyl estradiol (0." | 1.31 | Estrogenic activity of octylphenol, nonylphenol, bisphenol A and methoxychlor in rats. ( Bodman, GJ; Carey, SA; Cooper, RL; Ferrell, JM; Laws, SC, 2000) |
| " In most cases, however, the dose-response relationships were complex (non-monotonic), with effects at the highest dose examined being opposite to effects seen at lower doses." | 1.31 | Effects of prenatal exposure to low doses of diethylstilbestrol, o,p'DDT, and methoxychlor on postnatal growth and neurobehavioral development in male and female mice. ( Palanza, P; Parmigiani, S; vom Saal, FS, 2001) |
| " Resulting male pups (14-16 per group) then were dosed directly from postnatal day 7 to 42." | 1.31 | The hidden effect of estrogenic/antiandrogenic methoxychlor on spermatogenesis. ( Chapin, RE; Hardy, VB; Harris, MW; Johnson, L; Staub, C, 2002) |
| " The early pregnancy protocol provides dose-response information on the effects of short-term exposure of animals to compounds during early pregnancy." | 1.28 | Toxicological mechanisms of implantation failure. ( Cummings, AM, 1990) |
| " On Days 2 and 3 of pregnancy, 200 and 500 mg/kg/day MXC were found to accelerate embryo transport into the uterus; the 500 mg/kg/day dosage also reduced the total number of embryos recovered from the tract." | 1.28 | Methoxychlor accelerates embryo transport through the rat reproductive tract. ( Cummings, AM; Perreault, SD, 1990) |
| "In the present study rats were dosed from weaning, through puberty and gestation, to Day 15 of lactation with methoxychlor at 25, 50, 100, or 200 mg/kg/day." | 1.28 | A dose-response analysis of methoxychlor-induced alterations of reproductive development and function in the rat. ( Cooper, R; Ferrell, J; Goldman, J; Gray, LE; Laskey, J; Linder, R; Ostby, J; Rehnberg, G; Slott, V, 1989) |
| "0 ppm in samples from the low and high dosage sprays." | 1.27 | Methoxychlor residues in milk of cattle treated with Marlate 50 insecticide as a dermal spray. ( Clark, KJ; Coppock, CE; Ivey, MC; Ivie, GW, 1983) |
| "Methoxychlor-treated females did not differ from controls." | 1.27 | Alteration of behavioral sex differentiation by exposure to estrogenic compounds during a critical neonatal period: effects of zearalenone, methoxychlor, and estradiol in hamsters. ( Ferrell, JM; Gray, LE; Ostby, JS, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (12.28) | 18.7374 |
| 1990's | 7 (12.28) | 18.2507 |
| 2000's | 26 (45.61) | 29.6817 |
| 2010's | 16 (28.07) | 24.3611 |
| 2020's | 1 (1.75) | 2.80 |
| Authors | Studies |
|---|---|
| Martini, M | 1 |
| Froment, P | 1 |
| Franceschini, I | 1 |
| Pillon, D | 1 |
| Guibert, E | 1 |
| Cahier, C | 1 |
| Mhaouty-Kodja, S | 1 |
| Keller, M | 1 |
| Tajiki-Nishino, R | 1 |
| Watanabe, Y | 1 |
| Fukuyama, T | 1 |
| Abi Salloum, B | 1 |
| Steckler, TL | 2 |
| Herkimer, C | 1 |
| Lee, JS | 1 |
| Padmanabhan, V | 4 |
| Aoyama, H | 2 |
| Chapin, RE | 2 |
| Paoloni-Giacobino, A | 2 |
| Du, X | 1 |
| Zhang, H | 1 |
| Liu, Y | 1 |
| Yu, W | 1 |
| Huang, C | 1 |
| Li, X | 2 |
| Fagnant, HS | 1 |
| Uzumcu, M | 7 |
| Buckendahl, P | 1 |
| Dunn, MG | 1 |
| Shupper, P | 1 |
| Shapses, SA | 1 |
| Liu, S | 1 |
| Mao, B | 1 |
| Bai, Y | 1 |
| Liu, J | 1 |
| Li, H | 2 |
| Lian, Q | 1 |
| Ge, RS | 2 |
| Umeda, K | 1 |
| Kotake, Y | 1 |
| Miyara, M | 1 |
| Ishida, K | 1 |
| Sanoh, S | 1 |
| Ohta, S | 1 |
| Roepke, TA | 1 |
| Yang, JA | 1 |
| Yasrebi, A | 1 |
| Mamounis, KJ | 1 |
| Oruc, E | 1 |
| Zama, AM | 5 |
| Armenti, AE | 2 |
| Passantino, L | 1 |
| Sarma, HN | 1 |
| Savabieasfahani, M | 2 |
| Veiga-Lopez, A | 1 |
| Mahoney, MM | 1 |
| Stouder, C | 1 |
| Gore, AC | 1 |
| Walker, DM | 1 |
| Hojo, H | 1 |
| Takahashi, KL | 1 |
| Shimizu-Endo, N | 1 |
| Araki, M | 1 |
| Takeuchi-Kashimoto, Y | 1 |
| Saka, M | 1 |
| Teramoto, S | 2 |
| Guo, J | 1 |
| Deng, H | 1 |
| Zhu, Q | 1 |
| Zhao, B | 1 |
| Chen, B | 1 |
| Chu, Y | 1 |
| Alworth, LC | 1 |
| Howdeshell, KL | 1 |
| Ruhlen, RL | 1 |
| Day, JK | 1 |
| Lubahn, DB | 1 |
| Huang, TH | 1 |
| Besch-Williford, CL | 1 |
| vom Saal, FS | 2 |
| Takeuchi, Y | 1 |
| Kosaka, T | 1 |
| Hayashi, K | 1 |
| Takeda, M | 1 |
| Yoshida, T | 1 |
| Fujisawa, H | 1 |
| Maita, K | 1 |
| Harada, T | 1 |
| Masutomi, N | 3 |
| Shibutani, M | 3 |
| Takagi, H | 3 |
| Uneyama, C | 2 |
| Takahashi, N | 1 |
| Hirose, M | 3 |
| Lee, KY | 2 |
| Suzuki, M | 1 |
| Lee, HC | 1 |
| Chiba, S | 1 |
| Yonezawa, T | 1 |
| Nishihara, M | 1 |
| O'Brien, SM | 1 |
| Dunson, DB | 1 |
| White, KL | 3 |
| Germolec, DR | 2 |
| Booker, CD | 1 |
| Hernendez, DM | 1 |
| McCay, JA | 2 |
| Delclos, KB | 3 |
| Newbold, RR | 3 |
| Weis, C | 2 |
| Guo, TL | 3 |
| Laviola, G | 1 |
| Gioiosa, L | 1 |
| Adriani, W | 1 |
| Palanza, P | 2 |
| Musgrove, DL | 1 |
| Kaiser, J | 1 |
| Anway, MD | 1 |
| Cupp, AS | 1 |
| Skinner, MK | 1 |
| Flynn, KM | 1 |
| Ferguson, SA | 1 |
| Trubo, R | 1 |
| Amstislavsky, SY | 1 |
| Amstislavskaya, TG | 1 |
| Amstislavsky, VS | 1 |
| Tibeikina, MA | 1 |
| Osipov, KV | 1 |
| Eroschenko, VP | 2 |
| Fujita, H | 1 |
| Inoue, K | 1 |
| Mitsumori, K | 1 |
| Wang, XJ | 1 |
| Bartolucci-Page, E | 1 |
| Fenton, SE | 1 |
| You, L | 4 |
| Daftary, GS | 1 |
| Taylor, HS | 1 |
| Kannan, K | 1 |
| Astapova, O | 1 |
| Evans, NP | 1 |
| Ivey, MC | 1 |
| Ivie, GW | 1 |
| Coppock, CE | 1 |
| Clark, KJ | 1 |
| Cummings, AM | 6 |
| Laskey, J | 2 |
| Laws, SC | 1 |
| Carey, SA | 1 |
| Ferrell, JM | 2 |
| Bodman, GJ | 1 |
| Cooper, RL | 1 |
| Parmigiani, S | 1 |
| Casanova, M | 1 |
| Bartolucci, EJ | 2 |
| Fryczynski, MW | 1 |
| Dorman, DC | 1 |
| Everitt, JI | 1 |
| Gaido, KW | 1 |
| Ross, SM | 1 |
| Heck Hd, Hd | 1 |
| Zhang, XL | 1 |
| Bartolucci, E | 1 |
| Sar, M | 1 |
| McIntyre, BS | 1 |
| Sriperumbudur, R | 1 |
| Staub, C | 1 |
| Hardy, VB | 1 |
| Harris, MW | 1 |
| Johnson, L | 1 |
| Khera, KS | 1 |
| Whalen, C | 1 |
| Trivett, G | 1 |
| Johnson, DC | 1 |
| Sen, M | 1 |
| Dey, SK | 1 |
| Swartz, WJ | 1 |
| Corkern, M | 1 |
| Appel, RJ | 1 |
| Perreault, SD | 1 |
| Gray, LE | 4 |
| Ostby, J | 1 |
| Ferrell, J | 1 |
| Rehnberg, G | 1 |
| Linder, R | 1 |
| Cooper, R | 1 |
| Goldman, J | 1 |
| Slott, V | 1 |
| Ostby, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Identification and Characterization of the Methylation Abnormalities on Whole Genome Among Infertile Men[NCT01239186] | 49 participants (Actual) | Observational | 2009-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for methoxychlor and Pregnancy
| Article | Year |
|---|---|
Reproductive toxicities of methoxychlor based on estrogenic properties of the compound and its estrogenic metabolite, hydroxyphenyltrichloroethane.
Topics: Animals; Biotransformation; Endocrine Disruptors; Environmental Pollutants; Estrogens, Non-Steroidal | 2014 |
Epigenetic effects of methoxychlor and vinclozolin on male gametes.
Topics: Androgen Antagonists; Animals; Endocrine Disruptors; Environmental Exposure; Environmental Pollutant | 2014 |
Developmental reprogramming of reproductive and metabolic dysfunction in sheep: native steroids vs. environmental steroid receptor modulators.
Topics: Animals; Benzhydryl Compounds; Birth Weight; Embryonic Development; Endocrine Disruptors; Environmen | 2010 |
Endocrine regulation of HOX genes.
Topics: Animals; Benzhydryl Compounds; Diethylstilbestrol; Endometrium; Female; Gene Expression Regulation, | 2006 |
Methoxychlor as a model for environmental estrogens.
Topics: Animals; Environmental Exposure; Environmental Pollutants; Estrogens, Non-Steroidal; Female; Humans; | 1997 |
Methoxychlor.
Topics: Animals; Carcinogens; Embryo, Mammalian; Female; Food Contamination; Humans; Male; Methoxychlor; Mic | 1979 |
51 other studies available for methoxychlor and Pregnancy
| Article | Year |
|---|---|
Perinatal Exposure to Methoxychlor Affects Reproductive Function and Sexual Behavior in Mice.
Topics: Animals; Endocrine Disruptors; Estrous Cycle; Female; Insecticides; Kisspeptins; Methoxychlor; Mice; | 2020 |
Effect of prenatal exposure to combined immunosuppressive agrochemicals in a mouse model of allergic airway inflammation.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Drug Synergism; Eosinophils; Female; Immunosuppres | 2019 |
Developmental programming: impact of prenatal exposure to bisphenol-A and methoxychlor on steroid feedbacks in sheep.
Topics: Age Factors; Animals; Benzhydryl Compounds; Estradiol; Feedback, Physiological; Female; Gonadotropin | 2013 |
Perinatal exposure to low-dose methoxychlor impairs testicular development in C57BL/6 mice.
Topics: Animals; Estradiol; Female; Humans; Male; Maternal Exposure; Methoxychlor; Mice; Mice, Inbred C57BL; | 2014 |
Fetal and neonatal exposure to the endocrine disruptor, methoxychlor, reduces lean body mass and bone mineral density and increases cortical porosity.
Topics: Absorptiometry, Photon; Animals; Animals, Newborn; Body Composition; Bone and Bones; Bone Density; F | 2014 |
Effects of Methoxychlor and Its Metabolite Hydroxychlor on Human Placental 3β-Hydroxysteroid Dehydrogenase 1 and Aromatase in JEG-3 Cells.
Topics: Animals; Aromatase; Aromatase Inhibitors; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Dehydro | 2016 |
Methoxychlor and fenvalerate induce neuronal death by reducing GluR2 expression.
Topics: Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Female; Gene Expression; Metho | 2016 |
Regulation of arcuate genes by developmental exposures to endocrine-disrupting compounds in female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Benzhydryl Compounds; Brain-Derived Neurotrophic Factor; D | 2016 |
Developmental methoxychlor exposure affects multiple reproductive parameters and ovarian folliculogenesis and gene expression in adult rats.
Topics: Animals; Anti-Mullerian Hormone; Cholesterol Side-Chain Cleavage Enzyme; Dose-Response Relationship, | 2008 |
Fetal and neonatal exposure to the endocrine disruptor methoxychlor causes epigenetic alterations in adult ovarian genes.
Topics: Animals; Animals, Newborn; DNA Methylation; DNA Modification Methylases; Down-Regulation; Epigenesis | 2009 |
Developmental programming: impact of fetal exposure to endocrine-disrupting chemicals on gonadotropin-releasing hormone and estrogen receptor mRNA in sheep hypothalamus.
Topics: Animals; Benzhydryl Compounds; Endocrine Disruptors; Female; Fetal Development; Fetus; Gonadotropin- | 2010 |
Specific transgenerational imprinting effects of the endocrine disruptor methoxychlor on male gametes.
Topics: Animals; CpG Islands; DNA; DNA Methylation; Endocrine Disruptors; Epigenomics; Female; Genomic Impri | 2011 |
Early life exposure to endocrine-disrupting chemicals causes lifelong molecular reprogramming of the hypothalamus and premature reproductive aging.
Topics: Animals; Animals, Newborn; Base Sequence; Body Weight; CpG Islands; DNA Methylation; Endocrine Disru | 2011 |
Two-generation reproduction toxicity study in rats with methoxychlor.
Topics: Animal Feed; Animals; Body Weight; Endocrine System; Estrogens; Feeding Behavior; Female; Humans; In | 2012 |
Targeted genome-wide methylation and gene expression analyses reveal signaling pathways involved in ovarian dysfunction after developmental EDC exposure in rats.
Topics: Animals; DNA Methylation; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Genome; In | 2013 |
Effects of methoxychlor and its metabolite 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on 11β-hydroxysteroid dehydrogenase activities in vitro.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adult; Ani | 2013 |
Uterine responsiveness to estradiol and DNA methylation are altered by fetal exposure to diethylstilbestrol and methoxychlor in CD-1 mice: effects of low versus high doses.
Topics: Analysis of Variance; Animals; Body Weight; Carcinogens; Diethylstilbestrol; DNA Methylation; Dose-R | 2002 |
Thymic atrophy induced by methoxychlor in rat pups.
Topics: Abnormalities, Drug-Induced; Animals; Apoptosis; Atrophy; Body Weight; Female; Male; Methoxychlor; O | 2002 |
Impact of dietary exposure to methoxychlor, genistein, or diisononyl phthalate during the perinatal period on the development of the rat endocrine/reproductive systems in later life.
Topics: Administration, Oral; Animals; Body Weight; Endocrine System; Estrous Cycle; Female; Genistein; Male | 2003 |
Alteration of pituitary hormone-immunoreactive cell populations in rat offspring after maternal dietary exposure to endocrine-active chemicals.
Topics: Administration, Oral; Age Factors; Animals; Benzhydryl Compounds; Diet; Estrogens, Non-Steroidal; Fe | 2004 |
Effects of methoxychlor exposure during perinatal period on reproductive function after maturation in rats.
Topics: Animals; Copulation; Estrous Cycle; Female; Follicle Stimulating Hormone; Insecticides; Luteinizing | 2004 |
Bayesian multivariate logistic regression.
Topics: Algorithms; Animals; Bayes Theorem; Biometry; Female; Insecticides; Logistic Models; Male; Markov Ch | 2004 |
Dietary methoxychlor exposure modulates splenic natural killer cell activity, antibody-forming cell response and phenotypic marker expression in F0 and F1 generations of Sprague Dawley rats.
Topics: Animals; Animals, Newborn; Antibody-Producing Cells; Diet; Female; Immunoglobulin M; Immunologic Fac | 2005 |
D-amphetamine-related reinforcing effects are reduced in mice exposed prenatally to estrogenic endocrine disruptors.
Topics: Animals; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Conditioning, Op | 2005 |
Myelotoxicity in genistein-, nonylphenol-, methoxychlor-, vinclozolin- or ethinyl estradiol-exposed F1 generations of Sprague-Dawley rats following developmental and adult exposures.
Topics: Animals; Bone Marrow Cells; Cell Count; DNA; Erythropoietin; Ethinyl Estradiol; Female; Genistein; G | 2005 |
Developmental biology. Endocrine disrupters trigger fertility problems in multiple generations.
Topics: Androgen Antagonists; Animals; Endocrine Glands; Environmental Pollutants; Epigenesis, Genetic; Fema | 2005 |
Epigenetic transgenerational actions of endocrine disruptors and male fertility.
Topics: Androgen Antagonists; Animals; Crosses, Genetic; DNA Methylation; Endocrine Glands; Environmental Po | 2005 |
Long term dietary methoxychlor exposure in rats increases sodium solution consumption but has few effects on other sexually dimorphic behaviors.
Topics: Animals; Behavior, Animal; Birth Weight; Body Weight; Diet; Eating; Female; Food Preferences; Insect | 2005 |
Endocrine-disrupting chemicals probed as potential pathways to illness.
Topics: Abnormalities, Drug-Induced; Animals; Benzhydryl Compounds; Child, Preschool; Endocrine Glands; Endo | 2005 |
Reproductive abnormalities in adult male mice following preimplantation exposures to estradiol or pesticide methoxychlor.
Topics: Animals; Blastocyst; Estradiol; Female; Genitalia, Male; Insecticides; Litter Size; Male; Methoxychl | 2006 |
Impact of maternal dietary exposure to endocrine-acting chemicals on progesterone receptor expression in microdissected hypothalamic medial preoptic areas of rat offspring.
Topics: Animals; Diet; DNA Primers; Endocrine System; Estradiol Congeners; Ethinyl Estradiol; Female; Gene E | 2005 |
Altered mammary gland development in male rats exposed to genistein and methoxychlor.
Topics: Animals; Blotting, Western; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Gene Exp | 2006 |
Developmental programming: differential effects of prenatal exposure to bisphenol-A or methoxychlor on reproductive function.
Topics: Animals; Animals, Newborn; Benzhydryl Compounds; Birth Weight; Dose-Response Relationship, Drug; Est | 2006 |
Methoxychlor residues in milk of cattle treated with Marlate 50 insecticide as a dermal spray.
Topics: Administration, Topical; Aerosols; Animals; Cattle; Cattle Diseases; Diptera; Ectoparasitic Infestat | 1983 |
Effect of methoxychlor on ovarian steroidogenesis: role in early pregnancy loss.
Topics: Abortion, Spontaneous; Adrenal Glands; Animals; Estradiol; Estrus; Female; In Vitro Techniques; Meth | 1993 |
Estrogenic activity of octylphenol, nonylphenol, bisphenol A and methoxychlor in rats.
Topics: Animals; Benzhydryl Compounds; Binding, Competitive; Epithelial Cells; Estrogens, Non-Steroidal; Est | 2000 |
Effects of prenatal exposure to low doses of diethylstilbestrol, o,p'DDT, and methoxychlor on postnatal growth and neurobehavioral development in male and female mice.
Topics: Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Body Weight; Carcinogens; DDT; Diet | 2001 |
Combined effects of dietary phytoestrogen and synthetic endocrine-active compound on reproductive development in Sprague-Dawley rats: genistein and methoxychlor.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Endocrine Glands; Es | 2002 |
Genistein and methoxychlor modulate the activity of natural killer cells and the expression of phenotypic markers by thymocytes and splenocytes in F0 and F1 generations of Sprague-Dawley rats.
Topics: Animals; Body Weight; Estrogens, Non-Steroidal; Female; Flow Cytometry; Genetic Markers; Genistein; | 2002 |
Modulation of mammary gland development in prepubertal male rats exposed to genistein and methoxychlor.
Topics: Animals; Drug Synergism; Estrogens, Non-Steroidal; Female; Genistein; Insecticides; Isoflavones; Mal | 2002 |
The hidden effect of estrogenic/antiandrogenic methoxychlor on spermatogenesis.
Topics: Animals; Female; Insecticides; Male; Methoxychlor; Organ Size; Pregnancy; Rats; Sertoli Cells; Sperm | 2002 |
Teratogenicity studies on linuron, malathion, and methoxychlor in rats.
Topics: Animals; Female; Fetus; Gestational Age; Herbicides; Linuron; Malathion; Methoxychlor; Pregnancy; Ra | 1978 |
Differential effects of dichlorodiphenyltrichloroethane analogs, chlordecone, and 2,3,7,8-tetrachlorodibenzo-p-dioxin on establishment of pregnancy in the hypophysectomized rat.
Topics: Animals; Blastocyst; Chlordecone; DDT; Dichlorodiphenyl Dichloroethylene; Embryo Implantation; Estro | 1992 |
Effects of methoxychlor treatment of pregnant mice on female offspring of the treated and subsequent pregnancies.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Suckling; Body Weight; Dose-Response Relationship, Dr | 1992 |
Passage of methoxychlor in milk and reproductive organs of nursing female mice; 1. Light and scanning electron microscopic observations.
Topics: Animals; Animals, Suckling; Body Weight; Epithelium; Estradiol; Female; Genitalia, Female; Male; Mat | 1992 |
Toxicological mechanisms of implantation failure.
Topics: Animals; Decidua; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; | 1990 |
Methoxychlor accelerates embryo transport through the rat reproductive tract.
Topics: Animals; Blastocyst; Dose-Response Relationship, Drug; Embryonic Development; Estrus; Female; Methox | 1990 |
Antifertility effect of methoxychlor in female rats: dose- and time-dependent blockade of pregnancy.
Topics: Animals; Decidua; Dose-Response Relationship, Drug; Embryo Implantation; Female; Fertility; Methoxyc | 1989 |
A dose-response analysis of methoxychlor-induced alterations of reproductive development and function in the rat.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Estrus; Female; Male; Methoxychlor; Organ Si | 1989 |
Alteration of behavioral sex differentiation by exposure to estrogenic compounds during a critical neonatal period: effects of zearalenone, methoxychlor, and estradiol in hamsters.
Topics: Animals; Cricetinae; Estradiol; Estrus; Female; Male; Mesocricetus; Methoxychlor; Pregnancy; Resorci | 1985 |
Methoxychlor affects the decidual cell response of the uterus but not other progestational parameters in female rats.
Topics: Animals; Decidua; Embryo, Mammalian; Estrogens; Female; Fertility; Methoxychlor; Ovary; Pregnancy; R | 1987 |