methoxychlor has been researched along with Infertility, Male in 4 studies
Methoxychlor: An insecticide. Methoxychlor has estrogenic effects in mammals, among other effects.
Infertility, Male: The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methoxychlor is an organochlorine pesticide having a weak estrogenicity, which is estimated to be approximately 1000- to 14,000-fold less potent to a natural ligand, 17β-estradiol." | 2.50 | Reproductive toxicities of methoxychlor based on estrogenic properties of the compound and its estrogenic metabolite, hydroxyphenyltrichloroethane. ( Aoyama, H; Chapin, RE, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aoyama, H | 1 |
| Chapin, RE | 1 |
| Paoloni-Giacobino, A | 1 |
| Kaiser, J | 1 |
| Anway, MD | 1 |
| Cupp, AS | 1 |
| Uzumcu, M | 1 |
| Skinner, MK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Identification and Characterization of the Methylation Abnormalities on Whole Genome Among Infertile Men[NCT01239186] | 49 participants (Actual) | Observational | 2009-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for methoxychlor and Infertility, Male
| Article | Year |
|---|---|
Reproductive toxicities of methoxychlor based on estrogenic properties of the compound and its estrogenic metabolite, hydroxyphenyltrichloroethane.
Topics: Animals; Biotransformation; Endocrine Disruptors; Environmental Pollutants; Estrogens, Non-Steroidal | 2014 |
Epigenetic effects of methoxychlor and vinclozolin on male gametes.
Topics: Androgen Antagonists; Animals; Endocrine Disruptors; Environmental Exposure; Environmental Pollutant | 2014 |
2 other studies available for methoxychlor and Infertility, Male
| Article | Year |
|---|---|
Developmental biology. Endocrine disrupters trigger fertility problems in multiple generations.
Topics: Androgen Antagonists; Animals; Endocrine Glands; Environmental Pollutants; Epigenesis, Genetic; Fema | 2005 |
Epigenetic transgenerational actions of endocrine disruptors and male fertility.
Topics: Androgen Antagonists; Animals; Crosses, Genetic; DNA Methylation; Endocrine Glands; Environmental Po | 2005 |