methoxychlor has been researched along with Delayed Effects, Prenatal Exposure in 20 studies
Methoxychlor: An insecticide. Methoxychlor has estrogenic effects in mammals, among other effects.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to assess whether exposure to the estrogenic pesticide methoxychlor (MXC) during pregnancy would affect reproductive parameters not only in female offspring exposed prenatally, but also in those of a subsequent litter." | 3.68 | Effects of methoxychlor treatment of pregnant mice on female offspring of the treated and subsequent pregnancies. ( Corkern, M; Swartz, WJ, 1992) |
| "Methoxychlor (MXC) is a synthetic estrogen known as a persistent organochlorine and used as a pesticide." | 1.40 | Fetal and neonatal exposure to the endocrine disruptor, methoxychlor, reduces lean body mass and bone mineral density and increases cortical porosity. ( Buckendahl, P; Dunn, MG; Fagnant, HS; Shapses, SA; Shupper, P; Uzumcu, M, 2014) |
| "We previously performed dose-response studies of genistein, diisononyl phthalate, 4-nonylphenol, methoxychlor (MXC), and bisphenol A to examine the impact of maternal dietary exposure from gestational day 15 to postnatal day 10 on the development of rat reproductive system in later life." | 1.32 | Alteration of pituitary hormone-immunoreactive cell populations in rat offspring after maternal dietary exposure to endocrine-active chemicals. ( Hirose, M; Lee, KY; Masutomi, N; Shibutani, M; Takagi, H; Uneyama, C, 2004) |
| "Methoxychlor (MXC) is a non-steroidal pesticide that is known to possess estrogenic activity, and therefore may be potentially hazardous to the development and/or reproduction." | 1.32 | Effects of methoxychlor exposure during perinatal period on reproductive function after maturation in rats. ( Chiba, S; Lee, HC; Nishihara, M; Suzuki, M; Yonezawa, T, 2004) |
| " In most cases, however, the dose-response relationships were complex (non-monotonic), with effects at the highest dose examined being opposite to effects seen at lower doses." | 1.31 | Effects of prenatal exposure to low doses of diethylstilbestrol, o,p'DDT, and methoxychlor on postnatal growth and neurobehavioral development in male and female mice. ( Palanza, P; Parmigiani, S; vom Saal, FS, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 11 (55.00) | 29.6817 |
| 2010's | 7 (35.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martini, M | 1 |
| Froment, P | 1 |
| Franceschini, I | 1 |
| Pillon, D | 1 |
| Guibert, E | 1 |
| Cahier, C | 1 |
| Mhaouty-Kodja, S | 1 |
| Keller, M | 1 |
| Tajiki-Nishino, R | 1 |
| Watanabe, Y | 1 |
| Fukuyama, T | 1 |
| Abi Salloum, B | 1 |
| Steckler, TL | 2 |
| Herkimer, C | 1 |
| Lee, JS | 1 |
| Padmanabhan, V | 3 |
| Du, X | 1 |
| Zhang, H | 1 |
| Liu, Y | 1 |
| Yu, W | 1 |
| Huang, C | 1 |
| Li, X | 1 |
| Fagnant, HS | 1 |
| Uzumcu, M | 4 |
| Buckendahl, P | 1 |
| Dunn, MG | 1 |
| Shupper, P | 1 |
| Shapses, SA | 1 |
| Roepke, TA | 1 |
| Yang, JA | 1 |
| Yasrebi, A | 1 |
| Mamounis, KJ | 1 |
| Oruc, E | 1 |
| Zama, AM | 3 |
| Sarma, HN | 1 |
| Savabieasfahani, M | 2 |
| Veiga-Lopez, A | 1 |
| Masutomi, N | 2 |
| Shibutani, M | 2 |
| Takagi, H | 2 |
| Uneyama, C | 2 |
| Takahashi, N | 1 |
| Hirose, M | 2 |
| Lee, KY | 1 |
| Suzuki, M | 1 |
| Lee, HC | 1 |
| Chiba, S | 1 |
| Yonezawa, T | 1 |
| Nishihara, M | 1 |
| Laviola, G | 1 |
| Gioiosa, L | 1 |
| Adriani, W | 1 |
| Palanza, P | 2 |
| Guo, TL | 1 |
| Germolec, DR | 1 |
| Musgrove, DL | 1 |
| Delclos, KB | 1 |
| Newbold, RR | 1 |
| Weis, C | 1 |
| White, KL | 1 |
| Trubo, R | 1 |
| Amstislavsky, SY | 1 |
| Amstislavskaya, TG | 1 |
| Amstislavsky, VS | 1 |
| Tibeikina, MA | 1 |
| Osipov, KV | 1 |
| Eroschenko, VP | 1 |
| Kannan, K | 1 |
| Astapova, O | 1 |
| Evans, NP | 1 |
| Parmigiani, S | 1 |
| vom Saal, FS | 1 |
| You, L | 1 |
| Sar, M | 1 |
| Bartolucci, EJ | 1 |
| McIntyre, BS | 1 |
| Sriperumbudur, R | 1 |
| Swartz, WJ | 1 |
| Corkern, M | 1 |
1 review available for methoxychlor and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Developmental reprogramming of reproductive and metabolic dysfunction in sheep: native steroids vs. environmental steroid receptor modulators.
Topics: Animals; Benzhydryl Compounds; Birth Weight; Embryonic Development; Endocrine Disruptors; Environmen | 2010 |
19 other studies available for methoxychlor and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Perinatal Exposure to Methoxychlor Affects Reproductive Function and Sexual Behavior in Mice.
Topics: Animals; Endocrine Disruptors; Estrous Cycle; Female; Insecticides; Kisspeptins; Methoxychlor; Mice; | 2020 |
Effect of prenatal exposure to combined immunosuppressive agrochemicals in a mouse model of allergic airway inflammation.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Drug Synergism; Eosinophils; Female; Immunosuppres | 2019 |
Developmental programming: impact of prenatal exposure to bisphenol-A and methoxychlor on steroid feedbacks in sheep.
Topics: Age Factors; Animals; Benzhydryl Compounds; Estradiol; Feedback, Physiological; Female; Gonadotropin | 2013 |
Perinatal exposure to low-dose methoxychlor impairs testicular development in C57BL/6 mice.
Topics: Animals; Estradiol; Female; Humans; Male; Maternal Exposure; Methoxychlor; Mice; Mice, Inbred C57BL; | 2014 |
Fetal and neonatal exposure to the endocrine disruptor, methoxychlor, reduces lean body mass and bone mineral density and increases cortical porosity.
Topics: Absorptiometry, Photon; Animals; Animals, Newborn; Body Composition; Bone and Bones; Bone Density; F | 2014 |
Regulation of arcuate genes by developmental exposures to endocrine-disrupting compounds in female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Benzhydryl Compounds; Brain-Derived Neurotrophic Factor; D | 2016 |
Fetal and neonatal exposure to the endocrine disruptor methoxychlor causes epigenetic alterations in adult ovarian genes.
Topics: Animals; Animals, Newborn; DNA Methylation; DNA Modification Methylases; Down-Regulation; Epigenesis | 2009 |
Targeted genome-wide methylation and gene expression analyses reveal signaling pathways involved in ovarian dysfunction after developmental EDC exposure in rats.
Topics: Animals; DNA Methylation; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Genome; In | 2013 |
Impact of dietary exposure to methoxychlor, genistein, or diisononyl phthalate during the perinatal period on the development of the rat endocrine/reproductive systems in later life.
Topics: Administration, Oral; Animals; Body Weight; Endocrine System; Estrous Cycle; Female; Genistein; Male | 2003 |
Alteration of pituitary hormone-immunoreactive cell populations in rat offspring after maternal dietary exposure to endocrine-active chemicals.
Topics: Administration, Oral; Age Factors; Animals; Benzhydryl Compounds; Diet; Estrogens, Non-Steroidal; Fe | 2004 |
Effects of methoxychlor exposure during perinatal period on reproductive function after maturation in rats.
Topics: Animals; Copulation; Estrous Cycle; Female; Follicle Stimulating Hormone; Insecticides; Luteinizing | 2004 |
D-amphetamine-related reinforcing effects are reduced in mice exposed prenatally to estrogenic endocrine disruptors.
Topics: Animals; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Conditioning, Op | 2005 |
Myelotoxicity in genistein-, nonylphenol-, methoxychlor-, vinclozolin- or ethinyl estradiol-exposed F1 generations of Sprague-Dawley rats following developmental and adult exposures.
Topics: Animals; Bone Marrow Cells; Cell Count; DNA; Erythropoietin; Ethinyl Estradiol; Female; Genistein; G | 2005 |
Endocrine-disrupting chemicals probed as potential pathways to illness.
Topics: Abnormalities, Drug-Induced; Animals; Benzhydryl Compounds; Child, Preschool; Endocrine Glands; Endo | 2005 |
Reproductive abnormalities in adult male mice following preimplantation exposures to estradiol or pesticide methoxychlor.
Topics: Animals; Blastocyst; Estradiol; Female; Genitalia, Male; Insecticides; Litter Size; Male; Methoxychl | 2006 |
Developmental programming: differential effects of prenatal exposure to bisphenol-A or methoxychlor on reproductive function.
Topics: Animals; Animals, Newborn; Benzhydryl Compounds; Birth Weight; Dose-Response Relationship, Drug; Est | 2006 |
Effects of prenatal exposure to low doses of diethylstilbestrol, o,p'DDT, and methoxychlor on postnatal growth and neurobehavioral development in male and female mice.
Topics: Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Body Weight; Carcinogens; DDT; Diet | 2001 |
Modulation of mammary gland development in prepubertal male rats exposed to genistein and methoxychlor.
Topics: Animals; Drug Synergism; Estrogens, Non-Steroidal; Female; Genistein; Insecticides; Isoflavones; Mal | 2002 |
Effects of methoxychlor treatment of pregnant mice on female offspring of the treated and subsequent pregnancies.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Suckling; Body Weight; Dose-Response Relationship, Dr | 1992 |