methoxychlor has been researched along with Body Weight in 28 studies
Methoxychlor: An insecticide. Methoxychlor has estrogenic effects in mammals, among other effects.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of Methoxychlor (MXC) on the thymus was examined in rat pups that were delivered from dams receiving MXC at a dietary concentration of 0 or 1500 ppm for a period from pregnancy to lactation." | 7.71 | Thymic atrophy induced by methoxychlor in rat pups. ( Fujisawa, H; Harada, T; Hayashi, K; Kosaka, T; Maita, K; Takeda, M; Takeuchi, Y; Teramoto, S; Yoshida, T, 2002) |
| "The effect of Methoxychlor (MXC) on the thymus was examined in rat pups that were delivered from dams receiving MXC at a dietary concentration of 0 or 1500 ppm for a period from pregnancy to lactation." | 3.71 | Thymic atrophy induced by methoxychlor in rat pups. ( Fujisawa, H; Harada, T; Hayashi, K; Kosaka, T; Maita, K; Takeda, M; Takeuchi, Y; Teramoto, S; Yoshida, T, 2002) |
| " To investigate the effects of ethinylestradiol (EE) and methoxychlor (MXC) on development of ENU-induced uterine tumors, female p53 (+/-) mice and their wild-type littermates [p53 (+/+) mice] received an intraperitoneal injection of 120 mg/kg body weight (bw) of ENU, followed, in Group 1, by no further treatment; in Group 2, by a diet containing 1 ppm EE; in Group 3, by a diet containing 5 ppm EE for 4 weeks and 2." | 3.70 | Modifying effects of ethinylestradiol but not methoxychlor on N-ethyl-N-nitrosourea-induced uterine carcinogenesis in heterozygous p53-deficient CBA mice. ( Aoki, Y; Hirose, M; Mitsumori, K; Nagata, O; Onodera, H; Shimo, T; Takagi, H; Tamura, T; Yasuhara, K, 2000) |
| "This study was designed to assess whether exposure to the estrogenic pesticide methoxychlor (MXC) during pregnancy would affect reproductive parameters not only in female offspring exposed prenatally, but also in those of a subsequent litter." | 3.68 | Effects of methoxychlor treatment of pregnant mice on female offspring of the treated and subsequent pregnancies. ( Corkern, M; Swartz, WJ, 1992) |
| " To test this hypothesis, adult CD-1 female mice were dosed with vehicle control or MXC (64 mg/kg/day) for 20 days." | 1.42 | Exposure Duration-Dependent Ovarian Recovery in Methoxychlor-Treated Mice. ( Flaws, JA; Tannenbaum, LV, 2015) |
| "In vinclozolin-treated animals, the decreased estrogen-to-androgen ratios reported might be due to an increase of peripheral (adrenal) steroidogenesis." | 1.38 | Characterization of endocrine-disrupting chemicals based on hormonal balance disruption in male and female adult rats. ( Arnaud, M; Barouki, R; Cren-Olivé, C; Lecomte, A; Lemazurier, E; Quignot, N; Robidel, F; Tournier, M, 2012) |
| "Methoxychlor is an insecticide with estrogen-like activity, thus exposure during development might cause sexually dimorphic behavioral alterations." | 1.33 | Long term dietary methoxychlor exposure in rats increases sodium solution consumption but has few effects on other sexually dimorphic behaviors. ( Delclos, KB; Ferguson, SA; Flynn, KM; Newbold, RR, 2005) |
| "Methoxychlor (MC) was developed as a replacement for the banned pesticide DDT." | 1.33 | In vivo exposure of young adult male rats to methoxychlor reduces serum testosterone levels and ex vivo Leydig cell testosterone formation and cholesterol side-chain cleavage activity. ( Akgul, Y; Derk, RC; Murono, EP, 2006) |
| "Methoxychlor (MXC) is a pesticide that is known to bind to estrogen receptor alpha (ERalpha) and to induce atresia of antral ovarian follicles." | 1.33 | Methoxychlor induces atresia of antral follicles in ERalpha-overexpressing mice. ( Babus, JK; Flaws, JA; Frech, MS; Furth, PA; Gupta, RK; Koos, RD; Tomic, D, 2006) |
| " We thus found opposite effects of fetal exposure to a low and a high dose of DES on the uterine response to estradiol (inverted-U dose-response relationship)." | 1.31 | Uterine responsiveness to estradiol and DNA methylation are altered by fetal exposure to diethylstilbestrol and methoxychlor in CD-1 mice: effects of low versus high doses. ( Alworth, LC; Besch-Williford, CL; Day, JK; Howdeshell, KL; Huang, TH; Lubahn, DB; Ruhlen, RL; vom Saal, FS, 2002) |
| " In most cases, however, the dose-response relationships were complex (non-monotonic), with effects at the highest dose examined being opposite to effects seen at lower doses." | 1.31 | Effects of prenatal exposure to low doses of diethylstilbestrol, o,p'DDT, and methoxychlor on postnatal growth and neurobehavioral development in male and female mice. ( Palanza, P; Parmigiani, S; vom Saal, FS, 2001) |
| " In particular, the adverse effects were effectively detected in organ weights of accessory sex organs and histopathological examination." | 1.31 | A repeated 28-day oral dose toxicity study of methoxychlor in rats, based on the 'enhanced OECD test guideline 407' for screening endocrine-disrupting chemicals. ( Hatayama, K; Hirose, M; Katsumata, T; Kitamura, Y; Nakamura, A; Nakamura, H; Nishikawa, A; Nishimura, S; Okazaki, K; Okazaki, S; Tsuda, T, 2001) |
| " Female rats were gavaged with MXC at 0, 5, 50, or 150 mg/kg/day for the week before and the week after birth, whereupon the pups were directly dosed with MXC from postnatal day (pnd) 7." | 1.30 | The effects of perinatal/juvenile methoxychlor exposure on adult rat nervous, immune, and reproductive system function. ( Burka, LT; Chapin, RE; Collins, BJ; Davis, BJ; Harris, MW; Lockhart, AC; Mauney, MA; Moser, VC; Smialowicz, RJ; Ward, SM; Wilson, RE, 1997) |
| " Dose-response changes were observed in the oviduct and uterus but not vagina." | 1.28 | Morphological and biochemical alterations in reproductive tracts of neonatal female mice treated with the pesticide methoxychlor. ( Cooke, PS; Eroschenko, VP, 1990) |
| "In the present study rats were dosed from weaning, through puberty and gestation, to Day 15 of lactation with methoxychlor at 25, 50, 100, or 200 mg/kg/day." | 1.28 | A dose-response analysis of methoxychlor-induced alterations of reproductive development and function in the rat. ( Cooper, R; Ferrell, J; Goldman, J; Gray, LE; Laskey, J; Linder, R; Ostby, J; Rehnberg, G; Slott, V, 1989) |
| "Methoxychlor at 10,000 ppm was lethal to some rats, reduced food consumption and growth, and increased liver weight relative to body weight." | 1.26 | Methoxychlor effects on hepatic storage of vitamin A in rats. ( Cox, JH; Davison, KL, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (21.43) | 18.7374 |
| 1990's | 5 (17.86) | 18.2507 |
| 2000's | 13 (46.43) | 29.6817 |
| 2010's | 4 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tannenbaum, LV | 1 |
| Flaws, JA | 2 |
| Gore, AC | 1 |
| Walker, DM | 1 |
| Zama, AM | 1 |
| Armenti, AE | 1 |
| Uzumcu, M | 1 |
| Quignot, N | 1 |
| Arnaud, M | 1 |
| Robidel, F | 1 |
| Lecomte, A | 1 |
| Tournier, M | 1 |
| Cren-Olivé, C | 1 |
| Barouki, R | 1 |
| Lemazurier, E | 1 |
| Aoyama, H | 1 |
| Hojo, H | 1 |
| Takahashi, KL | 1 |
| Shimizu-Endo, N | 1 |
| Araki, M | 1 |
| Takeuchi-Kashimoto, Y | 1 |
| Saka, M | 1 |
| Teramoto, S | 2 |
| Ueda, M | 1 |
| Takagi, H | 4 |
| Onodera, H | 3 |
| Yasuhara, K | 3 |
| Takizawa, T | 1 |
| Imai, T | 1 |
| Mitsumori, K | 3 |
| Matsui, T | 1 |
| Hirose, M | 5 |
| Alworth, LC | 1 |
| Howdeshell, KL | 1 |
| Ruhlen, RL | 1 |
| Day, JK | 1 |
| Lubahn, DB | 1 |
| Huang, TH | 1 |
| Besch-Williford, CL | 1 |
| vom Saal, FS | 2 |
| Takeuchi, Y | 1 |
| Kosaka, T | 1 |
| Hayashi, K | 1 |
| Takeda, M | 1 |
| Yoshida, T | 1 |
| Fujisawa, H | 1 |
| Maita, K | 1 |
| Harada, T | 1 |
| Golub, MS | 1 |
| Hogrefe, CE | 1 |
| Germann, SL | 1 |
| Lasley, BL | 1 |
| Natarajan, K | 1 |
| Tarantal, AF | 1 |
| TULLNER, WW | 1 |
| EDGCOMB, JH | 1 |
| Masutomi, N | 1 |
| Shibutani, M | 1 |
| Uneyama, C | 1 |
| Takahashi, N | 1 |
| Flynn, KM | 1 |
| Delclos, KB | 1 |
| Newbold, RR | 1 |
| Ferguson, SA | 1 |
| Murono, EP | 1 |
| Derk, RC | 1 |
| Akgul, Y | 1 |
| Tomic, D | 1 |
| Frech, MS | 1 |
| Babus, JK | 1 |
| Gupta, RK | 1 |
| Furth, PA | 1 |
| Koos, RD | 1 |
| Zaleska-Freljan, KI | 1 |
| Kosicka, B | 1 |
| Chapin, RE | 1 |
| Harris, MW | 1 |
| Davis, BJ | 1 |
| Ward, SM | 1 |
| Wilson, RE | 1 |
| Mauney, MA | 1 |
| Lockhart, AC | 1 |
| Smialowicz, RJ | 1 |
| Moser, VC | 1 |
| Burka, LT | 1 |
| Collins, BJ | 1 |
| Shimo, T | 1 |
| Tamura, T | 2 |
| Aoki, Y | 1 |
| Nagata, O | 1 |
| Palanza, P | 1 |
| Parmigiani, S | 1 |
| Okazaki, K | 1 |
| Okazaki, S | 1 |
| Nishimura, S | 1 |
| Nakamura, H | 1 |
| Kitamura, Y | 1 |
| Hatayama, K | 1 |
| Nakamura, A | 1 |
| Tsuda, T | 1 |
| Katsumata, T | 1 |
| Nishikawa, A | 1 |
| Nasu, M | 1 |
| Takegawa, K | 1 |
| Guo, TL | 1 |
| Zhang, XL | 1 |
| Bartolucci, E | 1 |
| McCay, JA | 1 |
| White, KL | 1 |
| You, L | 1 |
| Davison, KL | 1 |
| Cox, JH | 1 |
| Swartz, WJ | 1 |
| Corkern, M | 1 |
| Appel, RJ | 1 |
| Eroschenko, VP | 3 |
| Cooke, PS | 2 |
| Gray, LE | 1 |
| Ostby, J | 1 |
| Ferrell, J | 1 |
| Rehnberg, G | 1 |
| Linder, R | 1 |
| Cooper, R | 1 |
| Goldman, J | 1 |
| Slott, V | 1 |
| Laskey, J | 1 |
| Lillie, RJ | 1 |
| Cecil, HC | 1 |
| Bitman, J | 1 |
| Foster, TS | 1 |
28 other studies available for methoxychlor and Body Weight
| Article | Year |
|---|---|
Exposure Duration-Dependent Ovarian Recovery in Methoxychlor-Treated Mice.
Topics: Animals; Body Weight; Breeding; Environmental Exposure; Estradiol; Female; Follicle Stimulating Horm | 2015 |
Early life exposure to endocrine-disrupting chemicals causes lifelong molecular reprogramming of the hypothalamus and premature reproductive aging.
Topics: Animals; Animals, Newborn; Base Sequence; Body Weight; CpG Islands; DNA Methylation; Endocrine Disru | 2011 |
Characterization of endocrine-disrupting chemicals based on hormonal balance disruption in male and female adult rats.
Topics: Adrenal Glands; Animals; Aromatase; Atrazine; Benzhydryl Compounds; Body Weight; Endocrine Disruptor | 2012 |
Two-generation reproduction toxicity study in rats with methoxychlor.
Topics: Animal Feed; Animals; Body Weight; Endocrine System; Estrogens; Feeding Behavior; Female; Humans; In | 2012 |
Enhancing effects of beta-estradiol 3-benzoate but not methoxychlor on the promotion/progression stage of chemically-induced mammary carcinogenesis in ovariectomized rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Disease Progression; Estradiol; Female; Mamm | 2002 |
Uterine responsiveness to estradiol and DNA methylation are altered by fetal exposure to diethylstilbestrol and methoxychlor in CD-1 mice: effects of low versus high doses.
Topics: Analysis of Variance; Animals; Body Weight; Carcinogens; Diethylstilbestrol; DNA Methylation; Dose-R | 2002 |
Thymic atrophy induced by methoxychlor in rat pups.
Topics: Abnormalities, Drug-Induced; Animals; Apoptosis; Atrophy; Body Weight; Female; Male; Methoxychlor; O | 2002 |
Effects of exogenous estrogenic agents on pubertal growth and reproductive system maturation in female rhesus monkeys.
Topics: Aging; Animals; Body Weight; Diethylstilbestrol; Eating; Estrogen Receptor alpha; Estrogens; Estroge | 2003 |
Cystic tubular nephropathy and decrease in testicular weight in rats following oral methoxychlor treatment.
Topics: Administration, Oral; Animals; Body Weight; Humans; Insecticides; Kidney; Male; Methoxychlor; Rats; | 1962 |
Impact of dietary exposure to methoxychlor, genistein, or diisononyl phthalate during the perinatal period on the development of the rat endocrine/reproductive systems in later life.
Topics: Administration, Oral; Animals; Body Weight; Endocrine System; Estrous Cycle; Female; Genistein; Male | 2003 |
Long term dietary methoxychlor exposure in rats increases sodium solution consumption but has few effects on other sexually dimorphic behaviors.
Topics: Animals; Behavior, Animal; Birth Weight; Body Weight; Diet; Eating; Female; Food Preferences; Insect | 2005 |
In vivo exposure of young adult male rats to methoxychlor reduces serum testosterone levels and ex vivo Leydig cell testosterone formation and cholesterol side-chain cleavage activity.
Topics: Animals; Body Weight; Cell Separation; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Chorioni | 2006 |
Methoxychlor induces atresia of antral follicles in ERalpha-overexpressing mice.
Topics: Animals; Base Sequence; Body Weight; DNA Primers; Estradiol; Estrogen Receptor alpha; Estrus; Female | 2006 |
Influence of bromfenvinfos alone and in mixture with methoxychlor on the blood indices of laboratory mice.
Topics: Animals; Blood; Blood Cell Count; Blood Proteins; Body Weight; Chlorfenvinphos; Erythrocytes; Female | 1982 |
The effects of perinatal/juvenile methoxychlor exposure on adult rat nervous, immune, and reproductive system function.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Cell Division; Female; Hemolytic Plaque Te | 1997 |
Modifying effects of ethinylestradiol but not methoxychlor on N-ethyl-N-nitrosourea-induced uterine carcinogenesis in heterozygous p53-deficient CBA mice.
Topics: Adenocarcinoma, Clear Cell; Animals; Body Weight; Carcinogens; Cocarcinogenesis; Diet; Drug Synergis | 2000 |
Effects of prenatal exposure to low doses of diethylstilbestrol, o,p'DDT, and methoxychlor on postnatal growth and neurobehavioral development in male and female mice.
Topics: Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Body Weight; Carcinogens; DDT; Diet | 2001 |
A repeated 28-day oral dose toxicity study of methoxychlor in rats, based on the 'enhanced OECD test guideline 407' for screening endocrine-disrupting chemicals.
Topics: Administration, Oral; Animals; Body Weight; Dose-Response Relationship, Drug; Endocrine System; Estr | 2001 |
Improvement of a two-stage carcinogenesis model to detect modifying effects of endocrine disrupting chemicals on thyroid carcinogenesis in rats.
Topics: Adenoma; Animals; Benzhydryl Compounds; Body Weight; Carcinogens; Cholesterol; Disease Models, Anima | 2002 |
Genistein and methoxychlor modulate the activity of natural killer cells and the expression of phenotypic markers by thymocytes and splenocytes in F0 and F1 generations of Sprague-Dawley rats.
Topics: Animals; Body Weight; Estrogens, Non-Steroidal; Female; Flow Cytometry; Genetic Markers; Genistein; | 2002 |
Methoxychlor effects on hepatic storage of vitamin A in rats.
Topics: Animals; Body Weight; Feeding Behavior; Liver; Methoxychlor; Organ Size; Rats; Time Factors; Vitamin | 1976 |
Effects of methoxychlor treatment of pregnant mice on female offspring of the treated and subsequent pregnancies.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Suckling; Body Weight; Dose-Response Relationship, Dr | 1992 |
Passage of methoxychlor in milk and reproductive organs of nursing female mice; 1. Light and scanning electron microscopic observations.
Topics: Animals; Animals, Suckling; Body Weight; Epithelium; Estradiol; Female; Genitalia, Female; Male; Mat | 1992 |
Morphological and biochemical alterations in reproductive tracts of neonatal female mice treated with the pesticide methoxychlor.
Topics: Animals; Animals, Newborn; Body Weight; DNA; Dose-Response Relationship, Drug; Estradiol; Female; Me | 1990 |
Inhibitory effects of technical grade methoxychlor on development of neonatal male mouse reproductive organs.
Topics: Animals; Animals, Newborn; Body Weight; Bulbourethral Glands; DNA; Epididymis; Estradiol; Male; Meth | 1990 |
A dose-response analysis of methoxychlor-induced alterations of reproductive development and function in the rat.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Estrus; Female; Male; Methoxychlor; Organ Si | 1989 |
Methoxychlor in chicken breeder diets.
Topics: Adipose Tissue; Administration, Oral; Animal Feed; Animals; Body Weight; Chickens; Egg Shell; Eggs; | 1973 |
Evaluation of the possible estrogenic activity of methoxychlor in the chicken by means of feeding trials.
Topics: Animal Feed; Animals; Animals, Newborn; Body Weight; Castration; Chickens; Diet; Diethylstilbestrol; | 1973 |