methoxychlor has been researched along with Atypical Endometrial Hyperplasia in 1 studies
Methoxychlor: An insecticide. Methoxychlor has estrogenic effects in mammals, among other effects.
Atypical Endometrial Hyperplasia: A benign form of endometrial hyperplasia with increased number of cells with atypia. The atypical cells are large and irregular and have an increased nuclear/cytoplasmic ratio. The risk of progression to endometrial carcinoma rises with the increasing degree of cell atypia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To investigate the effects of ethinylestradiol (EE) and methoxychlor (MXC) on development of ENU-induced uterine tumors, female p53 (+/-) mice and their wild-type littermates [p53 (+/+) mice] received an intraperitoneal injection of 120 mg/kg body weight (bw) of ENU, followed, in Group 1, by no further treatment; in Group 2, by a diet containing 1 ppm EE; in Group 3, by a diet containing 5 ppm EE for 4 weeks and 2." | 3.70 | Modifying effects of ethinylestradiol but not methoxychlor on N-ethyl-N-nitrosourea-induced uterine carcinogenesis in heterozygous p53-deficient CBA mice. ( Aoki, Y; Hirose, M; Mitsumori, K; Nagata, O; Onodera, H; Shimo, T; Takagi, H; Tamura, T; Yasuhara, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mitsumori, K | 1 |
| Shimo, T | 1 |
| Onodera, H | 1 |
| Takagi, H | 1 |
| Yasuhara, K | 1 |
| Tamura, T | 1 |
| Aoki, Y | 1 |
| Nagata, O | 1 |
| Hirose, M | 1 |
1 other study available for methoxychlor and Atypical Endometrial Hyperplasia
| Article | Year |
|---|---|
Modifying effects of ethinylestradiol but not methoxychlor on N-ethyl-N-nitrosourea-induced uterine carcinogenesis in heterozygous p53-deficient CBA mice.
Topics: Adenocarcinoma, Clear Cell; Animals; Body Weight; Carcinogens; Cocarcinogenesis; Diet; Drug Synergis | 2000 |