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methoxychlor and Adenocarcinoma, Clear Cell

methoxychlor has been researched along with Adenocarcinoma, Clear Cell in 1 studies

Methoxychlor: An insecticide. Methoxychlor has estrogenic effects in mammals, among other effects.

Adenocarcinoma, Clear Cell: An adenocarcinoma characterized by the presence of varying combinations of clear and hobnail-shaped tumor cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumors, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (From Holland et al., Cancer Medicine, 3d ed)

Research Excerpts

ExcerptRelevanceReference
" To investigate the effects of ethinylestradiol (EE) and methoxychlor (MXC) on development of ENU-induced uterine tumors, female p53 (+/-) mice and their wild-type littermates [p53 (+/+) mice] received an intraperitoneal injection of 120 mg/kg body weight (bw) of ENU, followed, in Group 1, by no further treatment; in Group 2, by a diet containing 1 ppm EE; in Group 3, by a diet containing 5 ppm EE for 4 weeks and 2."3.70Modifying effects of ethinylestradiol but not methoxychlor on N-ethyl-N-nitrosourea-induced uterine carcinogenesis in heterozygous p53-deficient CBA mice. ( Aoki, Y; Hirose, M; Mitsumori, K; Nagata, O; Onodera, H; Shimo, T; Takagi, H; Tamura, T; Yasuhara, K, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mitsumori, K1
Shimo, T1
Onodera, H1
Takagi, H1
Yasuhara, K1
Tamura, T1
Aoki, Y1
Nagata, O1
Hirose, M1

Other Studies

1 other study available for methoxychlor and Adenocarcinoma, Clear Cell

ArticleYear
Modifying effects of ethinylestradiol but not methoxychlor on N-ethyl-N-nitrosourea-induced uterine carcinogenesis in heterozygous p53-deficient CBA mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 58, Issue:1

    Topics: Adenocarcinoma, Clear Cell; Animals; Body Weight; Carcinogens; Cocarcinogenesis; Diet; Drug Synergis

2000