methoxyamine has been researched along with Glioma in 3 studies
methoxyamine: analytical reagent for aldehydes and ketones; strong irritant, can probably produce methemoglobinemia; RN given refers to parent cpd; structure
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the effects of β-elemene + methoxyamine, a DNA base-excision repair inhibitor, on the inhibition of glioma growth." | 7.79 | The cytotoxic effect of β-elemene against malignant glioma is enhanced by base-excision repair inhibitor methoxyamine. ( Hu, J; Liu, W; Shen, F; Shen, H; Zhang, J; Zhu, Y, 2013) |
| "Temozolomide (TMZ) is the preferred chemotherapeutic agent in the treatment of glioma following surgical resection and/or radiation." | 7.77 | N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide. ( Banze, LA; Brown, AR; Goellner, EM; Hamilton, RL; Moore, B; Sobol, RW; Svilar, D; Tang, JB; Trivedi, RN; Wang, XH, 2011) |
| "This study investigated the effects of β-elemene + methoxyamine, a DNA base-excision repair inhibitor, on the inhibition of glioma growth." | 3.79 | The cytotoxic effect of β-elemene against malignant glioma is enhanced by base-excision repair inhibitor methoxyamine. ( Hu, J; Liu, W; Shen, F; Shen, H; Zhang, J; Zhu, Y, 2013) |
| "Temozolomide (TMZ) is the preferred chemotherapeutic agent in the treatment of glioma following surgical resection and/or radiation." | 3.77 | N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide. ( Banze, LA; Brown, AR; Goellner, EM; Hamilton, RL; Moore, B; Sobol, RW; Svilar, D; Tang, JB; Trivedi, RN; Wang, XH, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, Y | 1 |
| Hu, J | 1 |
| Shen, F | 1 |
| Shen, H | 1 |
| Liu, W | 1 |
| Zhang, J | 1 |
| Wang, Y | 1 |
| Liu, L | 1 |
| Wu, C | 1 |
| Bulgar, A | 1 |
| Somoza, E | 1 |
| Zhu, W | 1 |
| Gerson, SL | 1 |
| Tang, JB | 1 |
| Svilar, D | 1 |
| Trivedi, RN | 1 |
| Wang, XH | 1 |
| Goellner, EM | 1 |
| Moore, B | 1 |
| Hamilton, RL | 1 |
| Banze, LA | 1 |
| Brown, AR | 1 |
| Sobol, RW | 1 |
3 other studies available for methoxyamine and Glioma
| Article | Year |
|---|---|
The cytotoxic effect of β-elemene against malignant glioma is enhanced by base-excision repair inhibitor methoxyamine.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Prolifer | 2013 |
Direct detection and quantification of abasic sites for in vivo studies of DNA damage and repair.
Topics: Animals; Base Sequence; Carbon Radioisotopes; Cell Line, Tumor; DNA Damage; DNA Repair; Female; Glio | 2009 |
N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain; Brain Neoplasms; Cell Line, | 2011 |