methoxyamine has been researched along with Astrocytoma, Grade IV in 2 studies
methoxyamine: analytical reagent for aldehydes and ketones; strong irritant, can probably produce methemoglobinemia; RN given refers to parent cpd; structure
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to evaluate the cellular responses to temozolomide treatment associated with methoxyamine (blocker of base excision repair) in glioblastoma cell lines, in order to test the hypothesis that the blockage of base excision repair pathway might sensitize glioblastoma cells to temozolomide." | 7.79 | Methoxyamine sensitizes the resistant glioblastoma T98G cell line to the alkylating agent temozolomide. ( Montaldi, AP; Sakamoto-Hojo, ET, 2013) |
| " The aim of this study was to evaluate the cellular responses to temozolomide treatment associated with methoxyamine (blocker of base excision repair) in glioblastoma cell lines, in order to test the hypothesis that the blockage of base excision repair pathway might sensitize glioblastoma cells to temozolomide." | 3.79 | Methoxyamine sensitizes the resistant glioblastoma T98G cell line to the alkylating agent temozolomide. ( Montaldi, AP; Sakamoto-Hojo, ET, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goellner, EM | 1 |
| Grimme, B | 1 |
| Brown, AR | 1 |
| Lin, YC | 1 |
| Wang, XH | 1 |
| Sugrue, KF | 1 |
| Mitchell, L | 1 |
| Trivedi, RN | 1 |
| Tang, JB | 1 |
| Sobol, RW | 1 |
| Montaldi, AP | 1 |
| Sakamoto-Hojo, ET | 1 |
2 other studies available for methoxyamine and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair.
Topics: Acrylamides; Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Survi | 2011 |
Methoxyamine sensitizes the resistant glioblastoma T98G cell line to the alkylating agent temozolomide.
Topics: Alkylating Agents; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Sur | 2013 |