methoxsalen has been researched along with Vitiligo in 107 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Vitiligo: A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Methoxypsoralen, a naturally occurring linear furocoumarin, has been successfully used in combination with ultraviolet (UV) A irradiation [psoralen plus UV (PUVA)] to manage psoriasis and vitiligo." | 8.80 | 5-Methoxypsoralen. A review of its effects in psoriasis and vitiligo. ( Goa, KL; McNeely, W, 1998) |
| "The present investigation aimed for the development and characterization of ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery and effective treatment against vitiligo." | 7.83 | Nanosized ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery against vitiligo: formulation optimization, in vitro evaluation and preclinical assessment. ( Beg, S; Garg, BJ; Garg, NK; Katare, OP; Singh, B, 2016) |
| "Galangin, the main active component of Alpinia officinarum Hance, was tested in a mouse model of vitiligo induced in C57BL/6 mice by the topical application of 2 mL of 2." | 7.80 | The effects of galangin on a mouse model of vitiligo induced by hydroquinone. ( Gao, L; Ge, CH; Huo, SX; Liu, XM; Peng, XM; Yan, M; Zhao, PP, 2014) |
| "Pimpinellin was recently found to be phototoxic, but an action spectrum of sphondin is reported for the first time." | 5.27 | Phototoxicity from furocoumarins (psoralens) of Heracleum laciniatum in a patient with vitiligo. Action spectrum studies on bergapten, pimpinellin, angelicin and sphondin. ( Kavli, G; Midelfart, K; Raa, J; Volden, G, 1983) |
| "5-Methoxypsoralen, a naturally occurring linear furocoumarin, has been successfully used in combination with ultraviolet (UV) A irradiation [psoralen plus UV (PUVA)] to manage psoriasis and vitiligo." | 4.80 | 5-Methoxypsoralen. A review of its effects in psoriasis and vitiligo. ( Goa, KL; McNeely, W, 1998) |
| "Psoralen compounds such as methoxsalen are photosensitizer agents used in conjunction with ultraviolet A (UVA) radiation exposure as photochemotherapy (Psoralens and ultraviolet-A therapy [PUVA therapy]) for certain epidermal skin disorders such as psoriasis and vitiligo." | 3.85 | Methoxsalen-induced macular toxicity. ( Maitray, A; Rishi, P, 2017) |
| "The present investigation aimed for the development and characterization of ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery and effective treatment against vitiligo." | 3.83 | Nanosized ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery against vitiligo: formulation optimization, in vitro evaluation and preclinical assessment. ( Beg, S; Garg, BJ; Garg, NK; Katare, OP; Singh, B, 2016) |
| "Galangin, the main active component of Alpinia officinarum Hance, was tested in a mouse model of vitiligo induced in C57BL/6 mice by the topical application of 2 mL of 2." | 3.80 | The effects of galangin on a mouse model of vitiligo induced by hydroquinone. ( Gao, L; Ge, CH; Huo, SX; Liu, XM; Peng, XM; Yan, M; Zhao, PP, 2014) |
| "5-methoxypsoralen (bergapten) has been used in the treatment of psoriasis and vitiligo, and as a sun tanning accelerator." | 3.77 | Percutaneous penetration of 5-methoxypsoralen in rhesus monkeys. ( Konda, S; Maibach, HI, 2011) |
| "The effect of erythemic UV irradiation on the phototoxic reactions caused by topical methoxsalen + UVA exposure was studied on normal skin, normal-looking skin of vitiligo patients, and vitiliginous skin." | 3.66 | Photoepicutaneous testing. UV-induced protection against photoxic reactions in normal and vitiliginous skin: a clinical and histological study. ( Niemi, KM; Suhonen, R, 1978) |
| "Eighteen patients with vitiligo were treated with two crystalline substances, xanthotoxin (Ammoidin) and imperatorin (Ammidin) from the plant Ammi majus." | 3.63 | Ammoidin (xanthotoxin) in the treatment of vitiligo. ( COUPERUS, M, 1954) |
| " The various drug dosage schedules investigated included 9 groups: 0." | 2.65 | Safety and therapeutic effectiveness of 8-methoxypsoralen, 4,5',8-trimethylpsoralen, and psoralen in vitiligo. ( Fitzpatrick, TB; Mosher, DB; Pathak, MA, 1984) |
| "Vitiligo is a disfiguring skin disease." | 2.42 | Vitiligo therapy: where are we now? ( Arroyo, MP; Tift, L, 2003) |
| "Vitiligo is an acute disease of skin with inflammation which means damage of melanocites, their defined partial paint lack." | 1.31 | [In vitro study of emulsions containing methoxsalen]. ( Aigner, Z; Józsa, P; Kata, M, 2000) |
| "Pimpinellin was recently found to be phototoxic, but an action spectrum of sphondin is reported for the first time." | 1.27 | Phototoxicity from furocoumarins (psoralens) of Heracleum laciniatum in a patient with vitiligo. Action spectrum studies on bergapten, pimpinellin, angelicin and sphondin. ( Kavli, G; Midelfart, K; Raa, J; Volden, G, 1983) |
| "PUVA therapy is effective in the treatment of vitiligo and hypopigmented scars." | 1.27 | Psoralen phototherapy and phototoxicity. ( Berakha, GJ; Lefkovits, G, 1985) |
| "The treatment of vitiligo has been unsatisfactory." | 1.26 | Trimethoxypsoralen in vitiligo. ( Annamalai, R; Lal, MB; Subhan, SA; Vasantha, M, 1976) |
| " Although a high chemical concentration and low dosage of UVA was a less time-consuming method of inducing phototoxicity, our results indicate that lower concentration and longer UVA exposure were less likely to induce undersirable blistering reactions." | 1.26 | Factors influencing methoxsalen phototoxicity in vitiliginous skin. ( Arora, SK; Willis, I, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 79 (73.83) | 18.7374 |
| 1990's | 12 (11.21) | 18.2507 |
| 2000's | 7 (6.54) | 29.6817 |
| 2010's | 8 (7.48) | 24.3611 |
| 2020's | 1 (0.93) | 2.80 |
| Authors | Studies |
|---|---|
| Niu, C | 2 |
| Yin, L | 1 |
| Nie, LF | 2 |
| Dou, J | 2 |
| Zhao, JY | 1 |
| Li, G | 2 |
| Aisa, HA | 2 |
| Pang, GX | 1 |
| Himit, H | 1 |
| Kabas, M | 1 |
| Mahmoud, DB | 1 |
| ElMeshad, AN | 1 |
| Fadel, M | 1 |
| Tawfik, A | 1 |
| Ramez, SA | 1 |
| Maitray, A | 1 |
| Rishi, P | 1 |
| Huo, SX | 1 |
| Liu, XM | 1 |
| Ge, CH | 1 |
| Gao, L | 1 |
| Peng, XM | 1 |
| Zhao, PP | 1 |
| Yan, M | 1 |
| Shoeibi, N | 1 |
| Taheri, A | 1 |
| Nikandish, M | 1 |
| Omidtabrizi, A | 1 |
| Khosravi, N | 1 |
| Kadkhoda, M | 1 |
| Moghaddam, SG | 1 |
| Garg, BJ | 1 |
| Garg, NK | 1 |
| Beg, S | 1 |
| Singh, B | 1 |
| Katare, OP | 1 |
| da Silva, VB | 1 |
| Kawano, DF | 1 |
| Carvalho, I | 1 |
| da Conceição, EC | 1 |
| de Freitas, O | 1 |
| da Silva, CH | 1 |
| Konda, S | 1 |
| Maibach, HI | 1 |
| Singh, S | 1 |
| Khandpur, S | 1 |
| Sharma, VK | 1 |
| Ramam, M | 1 |
| Lei, TC | 1 |
| Vieira, WD | 1 |
| Hearing, VJ | 1 |
| Arroyo, MP | 1 |
| Tift, L | 1 |
| LERNER, AB | 3 |
| DENTON, CR | 1 |
| FITZPATRICK, TB | 4 |
| COUPERUS, M | 1 |
| KANOF, NB | 1 |
| CHRISTIANSEN, JV | 1 |
| KELLY, EW | 1 |
| PINKUS, H | 1 |
| SHELDON, SA | 1 |
| HARRELL, ER | 1 |
| CURTIS, AC | 1 |
| ELLIOTT, JA | 3 |
| SCHUHMACHERS-BRENDLER, R | 2 |
| LONDON, ID | 1 |
| HOEKENGA, MT | 1 |
| GOLDBERG, LC | 1 |
| AKOVBIAN, AA | 1 |
| KAMZOLOVA, KP | 1 |
| ARNOLD, HL | 1 |
| EL-MOFTY, AM | 5 |
| EL-HAWARY, MF | 2 |
| FARAG, FB | 1 |
| LEONENKO, PM | 1 |
| ZAGRADNICEK, O | 1 |
| SMELOV, NS | 1 |
| BRAITSEV, AV | 2 |
| EL-HEFNAWI, H | 1 |
| RASHEED, A | 1 |
| STOLAR, R | 1 |
| TAMURA, M | 1 |
| HAMADA, I | 1 |
| TADZHIBAEV, TT | 1 |
| VINOKUROV, IN | 1 |
| STRANGE, HA | 1 |
| BALABANOV, K | 1 |
| DOGRAMADJIEV, I | 1 |
| HAMADA, T | 1 |
| INUI, H | 1 |
| AZUMA, N | 1 |
| LANCELEY, JL | 1 |
| LANCELEY, ES | 1 |
| JELLIFFE, DB | 1 |
| Parsad, D | 1 |
| Kanwar, AJ | 1 |
| Kumar, B | 1 |
| van Dijk, E | 1 |
| Becker, SW | 1 |
| Bäck, O | 1 |
| Hollström, E | 1 |
| Lidén, S | 1 |
| Thorburn, W | 1 |
| Pathak, MA | 2 |
| Mosher, DB | 1 |
| Lassus, A | 1 |
| Halme, K | 1 |
| Eskelinen, A | 1 |
| Ranki, A | 1 |
| Puska, P | 1 |
| Salo, O | 1 |
| Kavli, G | 1 |
| Midelfart, K | 1 |
| Raa, J | 1 |
| Volden, G | 1 |
| Kenney, JA | 5 |
| Grimes, PE | 2 |
| Minus, HR | 2 |
| Chakrabarti, SG | 3 |
| Enterline, J | 1 |
| Halder, R | 1 |
| Gough, JE | 1 |
| Ortonne, JP | 3 |
| Schmitt, D | 1 |
| Thivolet, J | 3 |
| Park, YM | 1 |
| Kim, TY | 1 |
| Kim, HO | 1 |
| Kim, CW | 1 |
| Khalid, M | 1 |
| Mujtaba, G | 1 |
| Haroon, TS | 1 |
| Halder, RM | 2 |
| Battle, EF | 1 |
| Smith, EM | 1 |
| el-Sawalhy, H | 1 |
| el-Mofty, M | 1 |
| Mignot, B | 1 |
| Guillaume, Y | 1 |
| Makki, S | 1 |
| Murret, E | 1 |
| Cavalli, E | 1 |
| Truong, TT | 1 |
| Thomassin, M | 1 |
| Guinchard, C | 1 |
| Abdel-Naser, MB | 1 |
| Hann, SK | 2 |
| Bystryn, JC | 1 |
| McNeely, W | 1 |
| Goa, KL | 1 |
| Shephard, SE | 1 |
| Panizzon, RG | 1 |
| Kata, M | 1 |
| Józsa, P | 1 |
| Aigner, Z | 1 |
| Falabella, R | 1 |
| Kreuter, A | 1 |
| Gambichler, T | 1 |
| Avermaete, A | 1 |
| Jansen, T | 1 |
| Altmeyer, P | 1 |
| von Kobyletzki, G | 1 |
| MacDonald, DM | 2 |
| Micoud, A | 2 |
| Fukuda, S | 1 |
| Benedetto, AV | 1 |
| Strauss, GH | 1 |
| Albertini, RJ | 1 |
| Krusinski, PA | 1 |
| Baughman, RD | 1 |
| Naik, RP | 1 |
| Singh, G | 1 |
| El-Mofty, A | 1 |
| Lynch, WS | 1 |
| Martin, JS | 1 |
| Roenigk, HH | 1 |
| Nada, MN | 1 |
| Abdel Aziz, MT | 1 |
| Gooray, DA | 1 |
| Suhonen, R | 1 |
| Niemi, KM | 1 |
| Hofmann, C | 1 |
| Bouattour, H | 1 |
| Chaabouni, M | 1 |
| Polemann, G | 1 |
| Karagezian, LA | 1 |
| Rostomian, RB | 1 |
| Bagdasarova, ZhG | 1 |
| Zala, L | 1 |
| Omar, A | 1 |
| Krebs, A | 1 |
| Carter, DM | 1 |
| Wolff, K | 1 |
| Schnedl, W | 1 |
| Annamalai, R | 1 |
| Subhan, SA | 1 |
| Vasantha, M | 1 |
| Lal, MB | 1 |
| Parrish, JA | 1 |
| Shea, C | 1 |
| Moller, R | 1 |
| Howitz, J | 1 |
| Arora, SK | 1 |
| Willis, I | 1 |
| Sinclair, R | 1 |
| Cho, MY | 1 |
| Im, S | 1 |
| Park, YK | 1 |
| Johnson, BA | 1 |
| Pradhan, TK | 1 |
| Ortel, B | 1 |
| Tanew, A | 1 |
| Hönigsmann, H | 1 |
| Berakha, GJ | 1 |
| Lefkovits, G | 1 |
| Nada, MM | 1 |
| Kligman, AM | 2 |
| Goldstein, FP | 2 |
| Petzoldt, D | 2 |
| Wiskemann, A | 1 |
| Sehgal, VN | 3 |
| Reich, AL | 1 |
| Faninger, A | 1 |
| Fulton, JE | 1 |
| Leyden, J | 1 |
| Papa, C | 1 |
| Dube, B | 1 |
| Chakraborty, DP | 1 |
| Shalupenko, VN | 1 |
3 reviews available for methoxsalen and Vitiligo
| Article | Year |
|---|---|
Vitiligo therapy: where are we now?
Topics: Child; Humans; Melanocytes; Methoxsalen; Phototherapy; PUVA Therapy; Skin Pigmentation; Skin Transpl | 2003 |
5-Methoxypsoralen. A review of its effects in psoriasis and vitiligo.
Topics: 5-Methoxypsoralen; Humans; Methoxsalen; Psoriasis; Vitiligo | 1998 |
The Seiji memorial lecture. Pigment stories: from vitiligo to melanomas and points in between.
Topics: Adult; Female; Humans; Hydroquinones; Male; Melanoma; Melanosis; Methoxsalen; Nevus, Pigmented; Para | 1992 |
8 trials available for methoxsalen and Vitiligo
| Article | Year |
|---|---|
Effect of oral photochemotherapy (8-methoxypsoralen + UVA) on the electrophysiologic function of retina.
Topics: Adult; Eczema; Electroretinography; Humans; Methoxsalen; Photochemotherapy; Photosensitizing Agents; | 2016 |
Comparison of efficacy and side-effect profile of oral PUVA vs. oral PUVA sol in the treatment of vitiligo: a 36-week prospective study.
Topics: Administration, Oral; Adolescent; Adult; Child; Female; Humans; Male; Methoxsalen; Middle Aged; Phot | 2013 |
Psoralen-ultraviolet A vs. narrow-band ultraviolet B phototherapy for the treatment of vitiligo.
Topics: Administration, Cutaneous; Adolescent; Adult; Female; Humans; Male; Methoxsalen; Middle Aged; PUVA T | 2006 |
Safety and therapeutic effectiveness of 8-methoxypsoralen, 4,5',8-trimethylpsoralen, and psoralen in vitiligo.
Topics: Ficusin; Follow-Up Studies; Furocoumarins; Humans; Melanins; Methoxsalen; Photochemotherapy; Photose | 1984 |
Comparison of 0.05% clobetasol propionate cream and topical Puvasol in childhood vitiligo.
Topics: Administration, Cutaneous; Atrophy; Child; Clobetasol; Drug Eruptions; Follow-Up Studies; Humans; Me | 1995 |
Clinical study of a new preparation of 8-methoxypsoralen in photochemotherapy.
Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Capsules; Child; Dose-Response Rel | 1994 |
6-Thioguanine resistant peripheral blood lymphocytes in humans following psoralen, long-wave ultraviolet light (PUVA) therapy.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Lymphocytes; Male; Methoxsalen; Middle Aged; Mutati | 1979 |
[Oral treatment of vitiligo with 8-methoxypsoralen and triamcinolone].
Topics: Administration, Oral; Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Follow-Up Studies; | 1974 |
96 other studies available for methoxsalen and Vitiligo
| Article | Year |
|---|---|
Synthesis and bioactivity of novel isoxazole chalcone derivatives on tyrosinase and melanin synthesis in murine B16 cells for the treatment of vitiligo.
Topics: Agaricales; Animals; Cell Survival; Chalcone; Dose-Response Relationship, Drug; Isoxazoles; Melanins | 2016 |
Synthesis and biological evaluation of furocoumarin derivatives on melanin synthesis in murine B16 cells for the treatment of vitiligo.
Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Ficusin; Furocoumarins; Melanins; Mice; | 2016 |
Photodynamic therapy fortified with topical oleyl alcohol-based transethosomal 8-methoxypsoralen for ameliorating vitiligo: Optimization and clinical study.
Topics: Administration, Cutaneous; Drug Delivery Systems; Fatty Alcohols; Humans; Methoxsalen; Photochemothe | 2022 |
Methoxsalen-induced macular toxicity.
Topics: Electrooculography; Electroretinography; Humans; Macula Lutea; Male; Methoxsalen; Middle Aged; Photo | 2017 |
The effects of galangin on a mouse model of vitiligo induced by hydroquinone.
Topics: Alpinia; Animals; Flavonoids; Hydroquinones; Male; Malondialdehyde; Melanins; Melanocytes; Methoxsal | 2014 |
Nanosized ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery against vitiligo: formulation optimization, in vitro evaluation and preclinical assessment.
Topics: Acrylates; Administration, Cutaneous; Animals; Chemistry, Pharmaceutical; Drug Delivery Systems; Dru | 2016 |
Psoralen and bergapten: in silico metabolism and toxicophoric analysis of drugs used to treat vitiligo.
Topics: 5-Methoxypsoralen; Animals; Biotransformation; Computational Biology; Computer Simulation; Drug Disc | 2009 |
Percutaneous penetration of 5-methoxypsoralen in rhesus monkeys.
Topics: 5-Methoxypsoralen; Administration, Cutaneous; Animals; Carbon Isotopes; Injections, Intramuscular; M | 2011 |
In vitro migration of melanoblasts requires matrix metalloproteinase-2: implications to vitiligo therapy by photochemotherapy.
Topics: alpha-MSH; Animals; Cell Adhesion Molecules; Cell Movement; Cells, Cultured; Dipeptides; Enzyme Indu | 2002 |
Clinical and experimental studies with 8-methoxypsoralen in vitiligo.
Topics: Coumarins; Humans; Methoxsalen; Ultraviolet Rays; Ultraviolet Therapy; Vitiligo | 1953 |
Ammoidin (xanthotoxin) in the treatment of vitiligo.
Topics: Adult; Ammi; Coumarins; Dermatitis; Female; Furocoumarins; Humans; Methoxsalen; Recurrence; Research | 1954 |
Melanin formation in vitiliginous skin under the influence of external applications of 8-methoxypsoralen.
Topics: Coumarins; Humans; Leadership; Melanins; Methoxsalen; Skin; Ultraviolet Rays; Ultraviolet Therapy; V | 1955 |
[Meladinine in therapy of vitiligo].
Topics: Coumarins; Humans; Methoxsalen; Vitiligo | 1955 |
Local application of 8-methoxypsoralen in vitiligo.
Topics: Coumarins; Methoxsalen; Vitiligo | 1955 |
Results in the treatment of vitiligo with 8-methoxypsoralen.
Topics: Coumarins; Humans; Methoxsalen; Vitiligo | 1956 |
The treatment of vitiligo with 8-methoxypsoralen.
Topics: Coumarins; Methoxsalen; Vitiligo | 1956 |
[Corrective dermatology. VI. Treatment of vitiligo with meladinine].
Topics: Coumarins; Dermatology; Methoxsalen; Vitiligo | 1956 |
[Corrective dermatology. VI. Treatment of vitiligo with meladinine].
Topics: Coumarins; Dermatology; Methoxsalen; Vitiligo | 1956 |
[Corrective dermatology. VI. Treatment of vitiligo with meladinine].
Topics: Coumarins; Dermatology; Methoxsalen; Vitiligo | 1956 |
[Corrective dermatology. VI. Treatment of vitiligo with meladinine].
Topics: Coumarins; Dermatology; Methoxsalen; Vitiligo | 1956 |
Methoxsalen in the treatment of vitiligo; an appraisal of the permanency of the repigmentation.
Topics: Humans; Khellin; Methoxsalen; Sunlight; Vitiligo | 1959 |
Clinical experiences with methoxsalen in the treatment of vitiligo.
Topics: Cholelithiasis; Furans; Humans; Methoxsalen; Vitiligo | 1959 |
Evaluation of methoxsalen in the treatment of vitiligo.
Topics: Furans; Humans; Methoxsalen; Vitiligo | 1959 |
Hair pigment and methoxsalen.
Topics: Furans; Hair; Humans; Methoxsalen; Pigmentation; Vitiligo | 1959 |
Experiences with methoxsalen in the Americam tropics.
Topics: Furans; Methoxsalen; Sunlight; Vitiligo | 1959 |
The clinical use of 8-methoxypsoralen.
Topics: Furans; Humans; Methoxsalen; Sunlight; Vitiligo | 1959 |
[Experience in the treatment of patients with vitiligo with Soviet Psoralen].
Topics: Ficusin; Humans; Methoxsalen; Vitiligo | 1961 |
[External use of 8-methoxypsoralen in vitiligo].
Topics: Humans; Methoxsalen; Vitiligo | 1960 |
The estimation of serum copper and blood glutathione in vitiligenous patients under the effect of psoralen treatment.
Topics: Copper; Ficusin; Glutathione; Humans; Methoxsalen; Regression Analysis; Vitiligo | 1961 |
[Meladinin therapy of patients with vitiligo].
Topics: Humans; Methoxsalen; Vitiligo | 1961 |
[Treatment of patients with vitiligo with extracts of Ammi majus (on the 70th birthday of Prof. Gavalovskii)].
Topics: Ammi; Humans; Methoxsalen; Plant Extracts; Vitiligo | 1961 |
[Results of meladinin therapy of patients with alopecia and vitiligo].
Topics: Alopecia; Humans; Methoxsalen; Vitiligo | 1961 |
Electrophoretic studies of serum proteins in vitiligenous patients treated with oral psoralens and ultra-violet irradiation.
Topics: Blood Proteins; Coumarins; Furocoumarins; Humans; Methoxsalen; Serum Albumin; Serum Globulins; Ultra | 1963 |
Induced alterations of vitiliginous skin.
Topics: Humans; Methoxsalen; Phenols; Quinacrine; Skin; Vitiligo | 1963 |
[On external meladinin treatment of ordinary vitiligo].
Topics: Humans; Khellin; Methoxsalen; Vitiligo | 1962 |
[TREATMENT OF VITILIGO PATIENTS WITH MELADININE].
Topics: Humans; Khellin; Methoxsalen; Ultraviolet Rays; Vitiligo | 1963 |
[NEW SOVIET DRUGS, AMMIFURIN AND BEROXAN, FOR THE TREATMENT OF ALOPECIA AREATA AND VITILIGO].
Topics: Alopecia; Alopecia Areata; Coumarins; Drug Combinations; Furocoumarins; Humans; Methoxsalen; Ultravi | 1963 |
[VITILIGO TREATED WITH PSORALEN DERIVATIVES].
Topics: Coumarins; Ficusin; Humans; Methoxsalen; Vitiligo | 1964 |
[ON THE TREATMENT OF VITILIGO].
Topics: Copper; Humans; Methoxsalen; Sunlight; Vitiligo | 1964 |
[STUDY ON THE EFFECTS OF 8-METHOXYPSORALEN ON LEUCODERMA VULGARE].
Topics: Adolescent; Biomedical Research; Child; Drug Therapy; Humans; Hypopigmentation; Methoxsalen; Researc | 1964 |
The treatment of vitiligo with 8-methoxypsordlen in Uganda children.
Topics: Humans; Methoxsalen; Uganda; Vitiligo | 1962 |
Treatment of vitiligo with 8-methoxypsoralen.
Topics: Adolescent; Adult; Female; Humans; Male; Methoxsalen; Ultraviolet Therapy; Vitiligo | 1967 |
Psoralen phototherapeutic agents.
Topics: Coumarins; Humans; Liver; Methoxsalen; Pigmentation Disorders; Skin Neoplasms; Substance-Related Dis | 1967 |
Absence of cataract ten years after treatment with 8-methoxypsoralen.
Topics: Adult; Aged; Cataract; Humans; Methoxsalen; Middle Aged; Photochemotherapy; Vitiligo | 1980 |
Treatment of vitiligo with oral methoxsalen and UVA.
Topics: Administration, Oral; Adult; Female; Humans; Male; Methoxsalen; Photochemotherapy; PUVA Therapy; Vit | 1984 |
Phototoxicity from furocoumarins (psoralens) of Heracleum laciniatum in a patient with vitiligo. Action spectrum studies on bergapten, pimpinellin, angelicin and sphondin.
Topics: 5-Methoxypsoralen; Adult; Anticonvulsants; Female; Furocoumarins; Humans; Intercalating Agents; Isom | 1983 |
How we treat vitiligo.
Topics: Administration, Oral; Administration, Topical; Child; Furocoumarins; Humans; Hydroquinones; Methods; | 1983 |
Determination of optimal topical photochemotherapy for vitiligo.
Topics: Administration, Topical; Adolescent; Adult; Aged; Child; Child, Preschool; Dose-Response Relationshi | 1982 |
PUVA-induced repigmentation of vitiligo: scanning electron microscopy of hair follicles.
Topics: Adult; Cell Division; Female; Hair; Humans; Male; Melanocytes; Methoxsalen; Photochemotherapy; Skin | 1980 |
Reproducible elevation of liver transaminases by topical 8-methoxypsoralen.
Topics: Adolescent; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Fema | 1994 |
Cutaneous malignancies in patients treated with psoralen photochemotherapy (PUVA) for vitiligo.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; F | 1995 |
British Photodermatology Group guidelines for PUVA.
Topics: 5-Methoxypsoralen; Cataract; Dermatitis, Atopic; Humans; Methoxsalen; Mycosis Fungoides; Psoriasis; | 1994 |
High-performance thin-layer chromatographic determination of 5-methoxypsoralen in serum from patients.
Topics: 5-Methoxypsoralen; Chromatography, Thin Layer; Humans; Methoxsalen; Psoriasis; PUVA Therapy; Reprodu | 1997 |
Oral psoralen with UV-A therapy releases circulating growth factor(s) that stimulates cell proliferation.
Topics: Administration, Oral; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Growth Subst | 1997 |
Carcinogenic risk of bath PUVA in comparison to oral PUVA therapy.
Topics: 5-Methoxypsoralen; Administration, Oral; Administration, Topical; Baths; DNA Adducts; Female; Humans | 1999 |
[In vitro study of emulsions containing methoxsalen].
Topics: Diffusion; Emulsions; Humans; Methoxsalen; Solubility; Structure-Activity Relationship; Vitiligo | 2000 |
What's new in the treatment of vitiligo.
Topics: Humans; Methoxsalen; Ointments; PUVA Therapy; Skin Pigmentation; Vitiligo | 2001 |
Localized vitiligo successfully treated with cream-psoralen + ultraviolet A.
Topics: Adult; Female; Humans; Methoxsalen; Ointments; PUVA Therapy; Skin Pigmentation; Vitiligo | 2001 |
PUVA-induced repigmentation of vitiligo: a histochemical (split-DOPA) and ultrastructural study.
Topics: Adult; Cell Count; Dihydroxyphenylalanine; Female; Histocytochemistry; Humans; Male; Melanocytes; Me | 1979 |
[Studies on the follicular melanocytes in the repigmented area of vitiligo after PUVA treatment (author's transl)].
Topics: Adolescent; Adult; Aged; Child, Preschool; Female; Humans; Male; Melanocytes; Methoxsalen; Middle Ag | 1979 |
The psoralens. An historical perspective.
Topics: Coumarins; Egypt; Ficusin; History, 20th Century; History, Ancient; History, Medieval; History, Mode | 1977 |
Nail pigmentation due to oral 8-methoxypsoralen.
Topics: Administration, Oral; Humans; Methoxsalen; Nail Diseases; Pigmentation Disorders; Vitiligo | 1979 |
Retrospective ocular study of patients receiving oral 8-methoxypsoralen and solar irradiation for the treatment of vitiligo.
Topics: Adult; Age Factors; Eye Diseases; Female; Follow-Up Studies; Heliotherapy; Humans; Male; Methoxsalen | 1979 |
Clinical results of photochemotherapy. The Cleveland Clinic experience.
Topics: Evaluation Studies as Topic; Humans; Methoxsalen; Middle Aged; Mycosis Fungoides; Ohio; Photochemoth | 1977 |
Clinical and laboratory evaluation of 8-methoxypsoralen toxicity.
Topics: Adult; Drug Evaluation; Female; Humans; Kidney; Kidney Function Tests; Liver; Liver Function Tests; | 1978 |
Determination of 8-methoxypsoralen in plasma by scanning fluorometry after thin-layer chromatography.
Topics: Animals; Chromatography, Thin Layer; Fluorometry; Humans; Methods; Methoxsalen; Rabbits; Vitiligo | 1978 |
Photoepicutaneous testing. UV-induced protection against photoxic reactions in normal and vitiliginous skin: a clinical and histological study.
Topics: Humans; Methoxsalen; Necrosis; Photosensitivity Disorders; Skin; Skin Tests; Ultraviolet Rays; Vitil | 1978 |
[Internal treatment of vitiligo].
Topics: Glucocorticoids; Humans; Methoxsalen; Pigmentation; Triamcinolone; Ultraviolet Therapy; Vitiligo | 1978 |
[Comparative analytical study of the effects of psoralens in vitiligo (findings in 70 patients) (author's transl)].
Topics: Adolescent; Adult; Aged; Child; Drug Evaluation; Female; Furocoumarins; Humans; Male; Methoxsalen; M | 1978 |
[Blacklight treatment of vitiligo].
Topics: Humans; Methoxsalen; Pigmentation; Ultraviolet Therapy; Vitiligo | 1978 |
[Treatment of vitiligo with ammifurin, beroxan and ultraviolet rays].
Topics: Acetone; Administration, Oral; Administration, Topical; Adolescent; Adult; Child; Ethanol; Female; F | 1978 |
[Repigmentation of vitiligo induced by oral photochemotherapy. Histoenzymological and ultrastructural study (author's transl)].
Topics: Humans; Melanocytes; Methoxsalen; Photochemotherapy; Vitiligo | 1978 |
Photo-onycholysis induced by 8-methoxypsoralen.
Topics: Administration, Oral; Adult; Cytoplasmic Granules; Epithelial Cells; Epithelium; Female; Fibroblasts | 1977 |
8-methoxypsoralen and UVA promote sister-chromatid exchanges.
Topics: Cells, Cultured; Chromatids; DNA Repair; Humans; Lymphocytes; Methoxsalen; Psoriasis; Ultraviolet Ra | 1976 |
Trimethoxypsoralen in vitiligo.
Topics: Adult; Child; Coumarins; Female; Follow-Up Studies; Humans; Male; Methoxsalen; Ointments; Photothera | 1976 |
Photochemotherapy of vitiligo. Use of orally administered psoralens and a high-intensity long-wave ultraviolet light system.
Topics: Administration, Oral; Adult; Coumarins; Female; Humans; Methoxsalen; Trioxsalen; Ultraviolet Therapy | 1976 |
Methoxsalen and multiple basal cell carcinomas.
Topics: Adult; Arsenic; Carcinoma, Basal Cell; Cocarcinogenesis; Female; Humans; Methoxsalen; Skin Neoplasms | 1976 |
[Experience in the use of a psoberan preparation in patients with vitiligo and alopecia].
Topics: Adolescent; Adult; Alopecia; Child; Coumarins; Drug Combinations; Drug Evaluation; Female; Ficusin; | 1975 |
Factors influencing methoxsalen phototoxicity in vitiliginous skin.
Topics: Administration, Topical; Adult; Child, Preschool; Dose-Response Relationship, Drug; Drug Evaluation; | 1976 |
A review of the 1992 annual meeting of the British Society for Investigative Dermatology.
Topics: Genes, p53; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Diseases; Vitiligo | 1992 |
Treatment of vitiligo with oral 5-methoxypsoralen.
Topics: Administration, Oral; Adolescent; Adult; Female; Humans; Male; Methoxsalen; Middle Aged; PUVA Therap | 1991 |
8-Methoxypsoralen levels in blood of vitiligo patients and in skin, ophthalmic fluids, and ocular tissues of the guinea pig.
Topics: Adult; Animals; Body Fluids; Chromatography, High Pressure Liquid; Eye; Female; Guinea Pigs; Humans; | 1986 |
Vitiligo treatment.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; DNA; Huma | 1986 |
Psoralen phototherapy and phototoxicity.
Topics: Adult; Female; Humans; Methoxsalen; Photosensitivity Disorders; PUVA Therapy; Substance-Related Diso | 1985 |
Vitiligo and its treatment.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; | 1974 |
Ineffectiveness of trioxsalen as an oral photosensitizer.
Topics: Acrylates; Administration, Oral; Adult; Benzofurans; Evaluation Studies as Topic; Humans; Methoxsale | 1973 |
Oral dosage in methoxsalen phototoxicity.
Topics: Administration, Oral; Adult; Humans; Male; Methoxsalen; Photosensitivity Disorders; Sunlight; Time F | 1973 |
[Vitiligo: new possibilities in the treatment and its adverse effects].
Topics: Drug Therapy, Combination; Methoxsalen; Triamcinolone; Vitiligo | 1973 |
[Local treatment of vitiligo with Meladinine].
Topics: Administration, Topical; Methoxsalen; Plant Extracts; Vitiligo | 1973 |
Letter: Trioxsalen therapy for vitiligo.
Topics: Coumarins; Furans; Humans; Methoxsalen; Radiation-Sensitizing Agents; Vitiligo | 1974 |
[Dermatitis toxica bullosa in vitiligines].
Topics: Humans; Male; Methoxsalen; Middle Aged; Photosensitivity Disorders; Vitiligo | 1972 |
Vitiligo and methoxsalen.
Topics: Humans; Methoxsalen; Solutions; Sunlight; Tablets; Vitiligo | 1971 |
Vitiligo treated by psoralens. A long-term follow-up study of the permanency of repigmentation.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Follow-Up Studies; Humans; Methoxsalen; Middle Age | 1971 |
Drugs for pigmentary disorders.
Topics: Dermatologic Agents; Humans; Methoxsalen; Pigmentation Disorders; Vitiligo | 1968 |
Treatment of vitiligo with topical methoxsalen and blacklite.
Topics: Adolescent; Adult; Chromatophores; Humans; Male; Methoxsalen; Middle Aged; Pigmentation; Skin; Ultra | 1969 |
Secretory state. A positive prognostic sign in vitiligo.
Topics: Age Factors; Factor Analysis, Statistical; Humans; Methoxsalen; Prognosis; Saliva; Time Factors; Vit | 1969 |
Treatment of vitiligo.
Topics: Benzopyrans; Diabetes Complications; Humans; India; Male; Methoxsalen; Sweat Glands; Vitiligo | 1969 |
Some biochemical and chemotherapeutic aspects of vitiligo.
Topics: Chemical Phenomena; Chemistry; Coumarins; Humans; Methoxsalen; Vitiligo | 1966 |
[Experience with Meladinin treatment of patients with vitiligo].
Topics: Adult; Female; Health Resorts; Humans; Male; Methoxsalen; Middle Aged; Vitiligo | 1966 |