methoxsalen has been researched along with Sunburn in 31 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Sunburn: An injury to the skin causing erythema, tenderness, and sometimes blistering and resulting from excessive exposure to the sun. The reaction is produced by the ultraviolet radiation in sunlight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because heat has been reported to influence adversely short- and long-term ultraviolet (UV)-radiation-induced skin damage in animals, we investigated the short-term effects of infrared radiation on sunburn and on phototoxic reactions to topical methoxsalen and anthracene in human volunteers." | 5.05 | The influence of infrared radiation on short-term ultraviolet-radiation-induced injuries. ( Kaidbey, KH; Kligman, AM; Witkowski, TA, 1982) |
| " Two clinical methods on human skin (inhibition of UVA-induced tanning with the use of a high-intensity UVA source and inhibition of methoxsalen plus UVA-induced phototoxicity) were compared with a method in animals (inhibition of UVA-induced sunburn cell production in mice treated with methoxsalen) and with two in vitro techniques (solution-dilution and sandwich spectrophotometry)." | 3.67 | Evaluating the UVA protection of sunscreens. ( Garmyn, M; Roelandts, R; Sohrabvand, N, 1989) |
| " The difference between the slopes of the dose-response curves of the control group and the four sunscreens was highly significant (p less than 0." | 1.28 | Modification of sunburn cell production in 8-MOP sensitized mouse epidermis: a method of assessing UVA sunscreen efficacy. ( Garmyn, M; Roelandts, R; Sohrabvand, N, 1989) |
| "In 8-methoxypsoralen (8-MOP) photosensitization, SBCs were also produced and this response is dose related with respect to long wave UVR dose." | 1.26 | The sunburn cell in mouse skin: preliminary quantitative studies on its production. ( Magnus, IA; Woodcock, A, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (87.10) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 1 (3.23) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DANIELS, F | 2 |
| HOPKINS, CE | 4 |
| FITZPATRICK, TB | 3 |
| STEGMAIER, OC | 2 |
| BECKER, SW | 1 |
| IMBRIE, JD | 2 |
| BERGERON, L | 1 |
| ARNOLD, HL | 1 |
| BERGERON, LL | 1 |
| BUCK, HW | 1 |
| MAGNUS, IA | 4 |
| PORTER, AD | 1 |
| KOOIJ, R | 1 |
| NESER, AT | 1 |
| SCOTT, FP | 1 |
| MACDONALD, EJ | 2 |
| GRIFFIN, AC | 1 |
| SMITH, L | 1 |
| GARRETT, H | 1 |
| BLACK, GL | 1 |
| BELISARIO, JC | 1 |
| DAVIS, CT | 1 |
| MEYER, J | 1 |
| HARTMAN, DL | 1 |
| DICKEY, RF | 1 |
| SCHENCK, RR | 1 |
| Kalu, PU | 1 |
| Myers, S | 1 |
| Epstein, JH | 1 |
| Smith, RW | 1 |
| O'Neill, TJ | 1 |
| Hammond, JE | 1 |
| Pathak, MA | 1 |
| Kaidbey, KH | 2 |
| Witkowski, TA | 1 |
| Kligman, AM | 2 |
| Young, AR | 3 |
| Chadwick, CA | 1 |
| Potten, CS | 1 |
| Cohen, AJ | 1 |
| Yasui, Y | 1 |
| Hirone, T | 1 |
| Geary, P | 1 |
| Woodcock, A | 1 |
| Gschnait, F | 1 |
| Pehamberger, H | 1 |
| Garmyn, M | 2 |
| Sohrabvand, N | 2 |
| Roelandts, R | 2 |
| Kaidbey, K | 1 |
| Gange, RW | 1 |
| Kooyers, WM | 1 |
2 reviews available for methoxsalen and Sunburn
| Article | Year |
|---|---|
Phototoxicity and photoallergy in man.
Topics: Acute Disease; Allergens; Anti-Infective Agents; Antigen-Antibody Complex; Chronic Disease; Dermatit | 1983 |
Sunscreens: topical and systemic approaches for protection of human skin against harmful effects of solar radiation.
Topics: 5-Methoxypsoralen; Administration, Oral; Administration, Topical; beta Carotene; Carotenoids; Chloro | 1982 |
1 trial available for methoxsalen and Sunburn
| Article | Year |
|---|---|
The influence of infrared radiation on short-term ultraviolet-radiation-induced injuries.
Topics: Adult; Anthracenes; Erythema; Female; Humans; Infrared Rays; Male; Methoxsalen; Photosensitivity Dis | 1982 |
28 other studies available for methoxsalen and Sunburn
| Article | Year |
|---|---|
Effects of oral methoxsalen (8-methoxypsoralen) on sunburn and suntan; a blind clinical trial.
Topics: Blindness; Coumarins; Humans; Methoxsalen; Sunburn; Suntan; Visually Impaired Persons | 1958 |
Methoxsalen and suntanning; a blind study.
Topics: Humans; Khellin; Methoxsalen; Sunbathing; Sunburn; Sunlight; Suntan | 1959 |
Prevention of sunburn and light allergy with methoxsalen.
Topics: Dermatitis; Furans; Humans; Hypersensitivity; Light; Methoxsalen; Sunburn; Sunlight | 1959 |
Increased erythema threshold six weeks after a single exposure to sunlight plus oral methoxsalen.
Topics: Erythema; Furans; Humans; Methoxsalen; Sunburn; Sunlight | 1959 |
Effect of methoxsalen on inability to tan.
Topics: Furans; Humans; Methoxsalen; Sunburn; Sunlight | 1959 |
The use of methoxsalen in sun tanning.
Topics: Furans; Humans; Methoxsalen; Sunbathing; Sunburn; Sunlight | 1959 |
Follow-up-study effect of oral methoxsalen (8-methoxypsoralen) on sunburn and suntan.
Topics: Follow-Up Studies; Humans; Methoxsalen; Sunburn; Suntan | 1960 |
The action spectrum of 8-methoxypsoralen for erythema in human skin. Preliminary studies with a monochromator.
Topics: Erythema; Humans; Methoxsalen; Skin; Sunburn | 1960 |
The action spectrum of 8-methoxypsoralen.
Topics: Humans; Methoxsalen; Sunburn | 1963 |
PSORALEN PROPHYLAXIS AGAINST SKIN CANCER: REPORT OF CLINICAL TRIAL I.
Topics: Ficusin; Geriatrics; Methoxsalen; Neoplasms; Skin Neoplasms; Sunburn; Toxicology | 1963 |
PSORALEN PROPHYLAXIS AGAINST SKIN CANCER: REPORT OF CLINICAL TRIAL II.
Topics: Ficusin; Humans; Methoxsalen; Neoplasms; Skin Neoplasms; Sunburn; Toxicology | 1963 |
[PHOTOPROTECTION BY INTERNAL ADMINISTRATION].
Topics: Adrenal Cortex Hormones; Anti-Allergic Agents; Antimalarials; gamma-Globulins; Glutathione; Histamin | 1964 |
PHOTODERMATITIS INDUCED BY DRUGS. II. PHOTODERMATITIS MEDICAMENTOSA.
Topics: Anti-Bacterial Agents; Benzoates; Chlorothiazide; Diphenhydramine; Drug Eruptions; Estrogens; Geriat | 1964 |
Controlled trial of methoxsalen in solar dermatitis of Chippewa Indians.
Topics: Dermatitis; Dermatitis, Phototoxic; Humans; Methoxsalen; Photosensitivity Disorders; Sunburn | 1960 |
Recreational use of Psoralens to fortify skin tanning.
Topics: Adult; Dermatologic Agents; Female; Heliotherapy; Humans; Methoxsalen; Photosensitizing Agents; Sunb | 2006 |
Burn injury: sunlight and a single dose of methoxsalen.
Topics: Adult; Humans; Male; Methoxsalen; Photochemotherapy; Sunburn; Sunlight | 1984 |
The sunburn cell in hairless mouse epidermis: quantitative studies with UV-A radiation and mono- and bifunctional psoralens.
Topics: Animals; DNA; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Epidermal Cel | 1982 |
An action spectrum for 8-MOP induced sunburn cells in mammalian epidermis.
Topics: Animals; Cell Count; Dose-Response Relationship, Radiation; Male; Methoxsalen; Mice; Mice, Nude; PUV | 1981 |
The time of onset and duration of 5-methoxypsoralen photochemoprotection from UVR-induced DNA damage in human skin.
Topics: 5-Methoxypsoralen; DNA; DNA Damage; Humans; Methoxsalen; Skin; Skin Pigmentation; Sunburn; Time Fact | 1994 |
Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting.
Topics: 5-Methoxypsoralen; Animals; Cell Count; Dermatitis, Phototoxic; Dose-Response Relationship, Radiatio | 1994 |
Burns related to the use of psoralens as a tanning agent.
Topics: Adult; Blister; Burns; Female; Humans; Methoxsalen; Photosensitizing Agents; Skin Pigmentation; Sunb | 1996 |
The sunburn cell in mouse skin: preliminary quantitative studies on its production.
Topics: Animals; Cell Survival; Dose-Response Relationship, Radiation; Fluoresceins; Male; Methoxsalen; Phot | 1976 |
Indomethacin does not affect PUVA induced erythema.
Topics: Adult; Humans; Indomethacin; Methoxsalen; Sunburn; Ultraviolet Rays | 1977 |
Further studies of photoaugmentation in humans: phototoxic reactions.
Topics: Adult; Coal Tar; Erythema; Humans; Male; Methoxsalen; Photosensitivity Disorders; Sunburn; Ultraviol | 1975 |
Modification of sunburn cell production in 8-MOP sensitized mouse epidermis: a method of assessing UVA sunscreen efficacy.
Topics: Animals; Cell Count; Cell Division; Dose-Response Relationship, Radiation; Epidermis; Female; Methox | 1989 |
Evaluating the UVA protection of sunscreens.
Topics: Adolescent; Adult; Humans; Male; Methoxsalen; Photosensitivity Disorders; Pigmentation; PUVA Therapy | 1989 |
Comparison of methods for assessing photoprotection against ultraviolet A in vivo.
Topics: Adolescent; Adult; Anthracenes; Benzoates; Benzophenones; Chalcones; Erythema; Female; Humans; Male; | 1987 |
Method for testing the efficacy of topical sunscreen preparations.
Topics: Albinism; Animals; Body Weight; Male; Methods; Methoxsalen; Photosensitivity Disorders; Rats; Sunbur | 1968 |