methoxsalen has been researched along with Scleroderma, Localized in 3 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Scleroderma, Localized: A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One patient with generalized morphea had stopped EP after 3 months because of loss of vascular access and could not be evaluated." | 2.68 | Extracorporeal photochemotherapy in systemic sclerosis and severe morphea. ( Cribier, B; Faradji, T; Grosshans, E; Le Coz, C; Oberling, F, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kitamura, Y | 1 |
| Namikawa, H | 1 |
| Hayashi, S | 1 |
| Yoshida, T | 1 |
| Suzuki, T | 1 |
| Hamasaki, Y | 1 |
| Yamazaki, S | 1 |
| Hatamochi, A | 1 |
| Cribier, B | 1 |
| Faradji, T | 1 |
| Le Coz, C | 1 |
| Oberling, F | 1 |
| Grosshans, E | 1 |
| Morison, WL | 1 |
1 trial available for methoxsalen and Scleroderma, Localized
| Article | Year |
|---|---|
Extracorporeal photochemotherapy in systemic sclerosis and severe morphea.
Topics: Adolescent; Adult; Aged; Arthritis; Disease Progression; Drug Tolerance; Esophageal Diseases; Female | 1995 |
2 other studies available for methoxsalen and Scleroderma, Localized
| Article | Year |
|---|---|
Effects of UVA irradiation following treatment with 8-methoxypsoralen on type I and type III collagen synthesis in normal and scleroderma fibroblast cultures.
Topics: Adult; Cells, Cultured; Collagen Type I; Collagen Type III; Collagenases; Dose-Response Relationship | 2009 |
Psoralen UVA therapy for linear and generalized morphea.
Topics: Adolescent; Adult; Dermatitis, Phototoxic; Female; Follow-Up Studies; Humans; Male; Methoxsalen; Mid | 1997 |