methoxsalen has been researched along with Recrudescence in 16 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six patients with extensive pityriasis alba were treated with oral methoxsalen, followed by exposure to midday summer sun or exposure to long-wave ultraviolet radiation in a psoralens plus ultraviolet A (PUVA) cabinet." | 7.67 | Oral methoxsalen photochemotherapy of extensive pityriasis alba. Preliminary report. ( Jaber, LA; Kurban, AK; Zaynoun, S, 1986) |
| " This study describes the efficacy of photochemotherapy, using orally administered methoxsalen and long-wave ultraviolet light in 91 patients with severe, generalized psoriasis." | 7.65 | Photochemotherapy for psoriasis with orally administered methoxsalen. ( Fitzpatrick, TB; Gilchrest, B; Gschnait, F; Hönigsmann, H; Parrish, JA; Pathak, MA; Tannenbaum, L; Wolff, KW, 1976) |
| "Six patients with extensive pityriasis alba were treated with oral methoxsalen, followed by exposure to midday summer sun or exposure to long-wave ultraviolet radiation in a psoralens plus ultraviolet A (PUVA) cabinet." | 3.67 | Oral methoxsalen photochemotherapy of extensive pityriasis alba. Preliminary report. ( Jaber, LA; Kurban, AK; Zaynoun, S, 1986) |
| "Nine patients with stages 2 or 3 mycosis fungoides (MF) and one with Sézary's syndrome were treated with oral methoxsalen and long-wave ultraviolet light." | 3.66 | Photochemotherapy for mycosis fungoides: a clinical and histological study. ( Cripps, DJ; Dufton, PA; Lowe, NJ; Vickers, CF, 1979) |
| " This study describes the efficacy of photochemotherapy, using orally administered methoxsalen and long-wave ultraviolet light in 91 patients with severe, generalized psoriasis." | 3.65 | Photochemotherapy for psoriasis with orally administered methoxsalen. ( Fitzpatrick, TB; Gilchrest, B; Gschnait, F; Hönigsmann, H; Parrish, JA; Pathak, MA; Tannenbaum, L; Wolff, KW, 1976) |
| "Eighteen patients with vitiligo were treated with two crystalline substances, xanthotoxin (Ammoidin) and imperatorin (Ammidin) from the plant Ammi majus." | 3.63 | Ammoidin (xanthotoxin) in the treatment of vitiligo. ( COUPERUS, M, 1954) |
| "Phototoxicity is the most significant short-term adverse effect of PUVA therapy." | 1.30 | PUVA-induced phototoxicity: incidence and causes. ( Beck, L; Marwaha, S; Morison, WL, 1997) |
| "Ten patients with chronic widespread plaque psoriasis, all of whom had previously completely cleared and suffered a subsequent widespread relapse after conventional PUVA therapy, were treated with a modified UVA dosage schedule, with psoralen formulation and dosage unchanged." | 1.28 | A modified dosage schedule for increased efficiency in PUVA treatment of psoriasis. ( Carabott, FM; Hawk, JL, 1989) |
| " The 8-methoxypsoralen dosage was approximately 0." | 1.26 | Treatment of resistant psoriasis with oral 8-methoxypsoralen and longwave ultraviolet light (PUVA). A treatment schedule and a follow-up study. ( Bro-Jorgensen, A; Howitz, J; Weismann, K, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (75.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ibbotson, SH | 1 |
| Dawe, RS | 1 |
| Dinkova-Kostova, AT | 1 |
| Weidlich, S | 1 |
| Farr, PM | 1 |
| Ferguson, J | 1 |
| Wolf, CR | 1 |
| Smith, G | 1 |
| COUPERUS, M | 1 |
| Schiener, R | 1 |
| Gottlöber, P | 1 |
| Müller, B | 1 |
| Williams, S | 1 |
| Pillekamp, H | 1 |
| Peter, RU | 1 |
| Kerscher, M | 1 |
| Morison, WL | 1 |
| Marwaha, S | 1 |
| Beck, L | 1 |
| Ravikumar, BC | 1 |
| Balachandran, C | 1 |
| Shenoi, SD | 1 |
| Sabitha, L | 1 |
| Ramnarayan, K | 1 |
| Weismann, K | 1 |
| Howitz, J | 1 |
| Bro-Jorgensen, A | 1 |
| Fritsch, P | 1 |
| Hönigsmann, H | 2 |
| Jaschke, E | 1 |
| Wolff, K | 1 |
| Cripps, DJ | 2 |
| Lowe, NJ | 2 |
| Nietsche, UB | 1 |
| Dufton, PA | 1 |
| Vickers, CF | 1 |
| Wolff, KW | 1 |
| Fitzpatrick, TB | 1 |
| Parrish, JA | 1 |
| Gschnait, F | 1 |
| Gilchrest, B | 1 |
| Pathak, MA | 1 |
| Tannenbaum, L | 1 |
| Jung, EG | 1 |
| Schoenian, R | 1 |
| Rodermund, OE | 1 |
| Stein, G | 1 |
| Carabott, FM | 1 |
| Hawk, JL | 1 |
| Zaynoun, S | 1 |
| Jaber, LA | 1 |
| Kurban, AK | 1 |
| Weber, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| the Association Between Serum Uric Acid Levels and the Risk of Metabolic Syndrome in Type 2 Diabetes Mellitus[NCT04575389] | 100 participants (Anticipated) | Observational | 2020-10-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for methoxsalen and Recrudescence
| Article | Year |
|---|---|
PUVA-gel vs. PUVA-bath therapy for severe recalcitrant palmoplantar dermatoses. A randomized, single-blinded prospective study.
Topics: Adult; Aged; Baths; Eczema; Female; Foot Dermatoses; Gels; Hand Dermatoses; Humans; Male; Methoxsale | 2005 |
[Photochemotherapy of psoriasis: increasing its effectiveness with an oral aromatic retinoid (clinical results in 134 patients) (author's transl)].
Topics: Administration, Oral; Clinical Trials as Topic; Follow-Up Studies; Humans; Methoxsalen; Psoriasis; R | 1978 |
14 other studies available for methoxsalen and Recrudescence
| Article | Year |
|---|---|
Glutathione S-transferase genotype is associated with sensitivity to psoralen-ultraviolet A photochemotherapy.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Erythema; Female; Gene Expression; Genoty | 2012 |
Ammoidin (xanthotoxin) in the treatment of vitiligo.
Topics: Adult; Ammi; Coumarins; Dermatitis; Female; Furocoumarins; Humans; Methoxsalen; Recurrence; Research | 1954 |
PUVA-induced phototoxicity: incidence and causes.
Topics: Clinical Protocols; Dermatitis, Phototoxic; Doxycycline; Drug Interactions; Female; Herpes Zoster; H | 1997 |
Disseminate and recurrent infundibulofolliculitis: response to psoralen plus UVA therapy.
Topics: Adult; Female; Folliculitis; Humans; Methoxsalen; Photochemotherapy; Photosensitizing Agents; Recurr | 1999 |
Treatment of resistant psoriasis with oral 8-methoxypsoralen and longwave ultraviolet light (PUVA). A treatment schedule and a follow-up study.
Topics: Follow-Up Studies; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Recurrence; Ultraviolet Therap | 1977 |
Photochemotherapy for psoriasis remission times. Psoralens and UV-A and combined photochemotherapy with anthralin.
Topics: Adolescent; Adult; Aged; Anthracenes; Anthralin; Child; Drug Therapy, Combination; Female; Humans; M | 1979 |
Photochemotherapy of psoriasis.
Topics: Female; Humans; Methoxsalen; Photochemotherapy; Pregnancy; Psoriasis; Recurrence; Time Factors | 1978 |
Photochemotherapy for mycosis fungoides: a clinical and histological study.
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Photochemotherapy; R | 1979 |
Photochemotherapy for psoriasis with orally administered methoxsalen.
Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; Dose-Response Relationship, | 1976 |
[Topical photochemotherapy of warts].
Topics: Administration, Topical; Female; Foot; Forearm; Humans; Male; Methoxsalen; Recurrence; Ultraviolet T | 1976 |
[Treatment of psoriasis. New possibility of psoriasis treatment using long-wave UV light and a photosensitizer].
Topics: Female; Humans; Male; Methods; Methoxsalen; Psoriasis; Recurrence; Remission, Spontaneous; Ultraviol | 1975 |
A modified dosage schedule for increased efficiency in PUVA treatment of psoriasis.
Topics: Humans; Methoxsalen; Psoriasis; PUVA Therapy; Recurrence; Time Factors; Ultraviolet Rays | 1989 |
Oral methoxsalen photochemotherapy of extensive pityriasis alba. Preliminary report.
Topics: Adult; Female; Humans; Methoxsalen; Photochemotherapy; Pityriasis; Recurrence | 1986 |
Combined 8-methoxypsoralen and black light therapy of psoriasis. Technique and results.
Topics: Adolescent; Adult; Dermatitis; Foot; Hand; Humans; Male; Methods; Methoxsalen; Middle Aged; Psoriasi | 1974 |