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methoxsalen and Pregnancy

methoxsalen has been researched along with Pregnancy in 5 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Because oral methoxsalen and UV-A radiation (PUVA) therapy is mutagenic, concern exists about the potential for teratogenic effects resulting from the use of this therapy at the time of conception and during pregnancy."9.07Outcomes of pregnancies among women and partners of men with a history of exposure to methoxsalen photochemotherapy (PUVA) for the treatment of psoriasis. ( Lange, R; Stern, RS, 1991)
"Because oral methoxsalen and UV-A radiation (PUVA) therapy is mutagenic, concern exists about the potential for teratogenic effects resulting from the use of this therapy at the time of conception and during pregnancy."5.07Outcomes of pregnancies among women and partners of men with a history of exposure to methoxsalen photochemotherapy (PUVA) for the treatment of psoriasis. ( Lange, R; Stern, RS, 1991)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Garbis, H1
Eléfant, E1
Bertolotti, E1
Robert, E1
Serafini, MA1
Prapas, N1
Lohrisch, I1
Heilmann, S1
Haustein, UF1
Nietsche, UB1
Stern, RS1
Lange, R1
Ivie, GW1
Beier, RC1
Bull, DL1
Oertli, EH1

Trials

1 trial available for methoxsalen and Pregnancy

ArticleYear
Outcomes of pregnancies among women and partners of men with a history of exposure to methoxsalen photochemotherapy (PUVA) for the treatment of psoriasis.
    Archives of dermatology, 1991, Volume: 127, Issue:3

    Topics: Abortion, Induced; Adult; Cohort Studies; Drug Evaluation; Female; Fetal Death; Follow-Up Studies; H

1991

Other Studies

4 other studies available for methoxsalen and Pregnancy

ArticleYear
Pregnancy outcome after periconceptional and first-trimester exposure to methoxsalen photochemotherapy.
    Archives of dermatology, 1995, Volume: 131, Issue:4

    Topics: Female; Fertilization; Follow-Up Studies; Humans; Infant, Newborn; Male; Methoxsalen; Pregnancy; Pre

1995
[Impetigo herpetiformis and PUVA-treatment (author's transl)].
    Dermatologische Monatschrift, 1979, Volume: 165, Issue:9

    Topics: Administration, Oral; Adult; Female; Humans; Impetigo; Methoxsalen; Photochemotherapy; Pregnancy; Pr

1979
Photochemotherapy of psoriasis.
    International journal of dermatology, 1978, Volume: 17, Issue:2

    Topics: Female; Humans; Methoxsalen; Photochemotherapy; Pregnancy; Psoriasis; Recurrence; Time Factors

1978
Fate of [14C]xanthotoxin (8-methoxypsoralen) in a goat and in bovine ruminal fluid.
    American journal of veterinary research, 1986, Volume: 47, Issue:4

    Topics: Animals; Carbon Radioisotopes; Cattle; Feces; Female; Goats; Kinetics; Lactation; Methoxsalen; Milk;

1986