methoxsalen has been researched along with Parapsoriasis in 4 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Parapsoriasis: The term applied to a group of relatively uncommon inflammatory, maculopapular, scaly eruptions of unknown etiology and resistant to conventional treatment. Eruptions are both psoriatic and lichenoid in appearance, but the diseases are distinct from psoriasis, lichen planus, or other recognized dermatoses. Proposed nomenclature divides parapsoriasis into two distinct subgroups, PITYRIASIS LICHENOIDES and parapsoriasis en plaques (small- and large-plaque parapsoriasis).
| Excerpt | Relevance | Reference |
|---|---|---|
| " In one patient who showed a lower absorption rate of 8-MOP plasma levels varied from 0-126 ng/ml." | 1.26 | Intraindividual variations of 8-methoxypsoralen plasma levels. ( Korting, HC; Schäfer-Korting, M, 1982) |
| "Plasma and skin blister fluid levels of 8-MOP are determined 2 h following oral administration of 40-60 mg 8-MOP." | 1.26 | Determination of 8-methoxypsoralen levels in plasma and skin suction blister fluid by a new sensitive fluorodensitometric method. ( Korting, HC; Mutschler, E; Roser-Maass, E; Schäfer-Korting, M, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schäfer-Korting, M | 2 |
| Korting, HC | 2 |
| Roser-Maass, E | 1 |
| Mutschler, E | 1 |
| Vella Briffa, D | 1 |
| Warin, AP | 1 |
| Calnan, CD | 1 |
| Laksmipathi, T | 1 |
| Gould, P | 1 |
| Johnson, BE | 1 |
| Mackenzie, LA | 1 |
| Frain-Bell, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Single Arm Study of Extracorporeal Photoimmune Therapy With Uvadex For Corticosteroid Sparing in Patients With Corticosteroid-Dependent Crohn's Disease Who May Also Be Refractory or Intolerant to Immunosuppressants and/or Anti-Tumor Necrosis Factor Agen[NCT00056355] | Phase 1 | 10 participants | Interventional | 2003-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for methoxsalen and Parapsoriasis
| Article | Year |
|---|---|
Intraindividual variations of 8-methoxypsoralen plasma levels.
Topics: Adult; Aged; Biological Availability; Female; Humans; Intestinal Absorption; Liver; Male; Metabolic | 1982 |
Determination of 8-methoxypsoralen levels in plasma and skin suction blister fluid by a new sensitive fluorodensitometric method.
Topics: Adult; Aged; Blister; Densitometry; Exudates and Transudates; Female; Fluorometry; Humans; Male; Met | 1982 |
Parakeratosis variegata: a report of two cases and their treatment with PUVA.
Topics: Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Parapsoriasis; Photochemoth | 1979 |
Proceedings: Photochemotherapy. A study of its efficacy in fifty patients suffering from psoriasis and other dermatoses.
Topics: Humans; Methoxsalen; Mycosis Fungoides; Parapsoriasis; Psoriasis; Skin Neoplasms; Ultraviolet Therap | 1976 |