methoxsalen has been researched along with Palmoplantaris Pustulosis in 472 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our data indicate that in bath-PUVA treatment the use of a high (5 mg/L) methoxsalen concentration is substantially more effective in clearing chronic plaque-type psoriasis than a low (1 mg/L) concentration." | 9.12 | Randomized, double-blind comparison of 1 mg/L versus 5 mg/L methoxsalen bath-PUVA therapy for chronic plaque-type psoriasis. ( Hönigsmann, H; Konschitzky, R; Seeber, A; Tanew, A; Treitl, C; Vongthongsri, R, 2006) |
| "A bilateral comparison study of the therapeutic effects of broad-band ultraviolet (UBV) (FS-40 Sunlamp bulbs) radiation versus UVB radiation plus methoxsalen was conducted in patients with psoriasis." | 9.08 | Combination of methoxsalen and ultraviolet B (UVB) versus UVB radiation alone in treatment of psoriasis: a bilateral comparison study. ( Morison, WL, 1995) |
| "Thirty-eight patients with plaque-type psoriasis were enrolled in a double-blind psoralen plus ultraviolet A (PUVA) treatment study comparing the efficacy and side effects of 5-methoxypsoralen (5-MOP) and 8-methoxypsoralen (8-MOP)." | 9.07 | Treatment of psoriasis with psoralens and ultraviolet A. A double-blind comparison of 8-methoxypsoralen and 5-methoxypsoralen. ( Berg, M; Ros, AM, 1994) |
| "5-methoxypsoralen (5-MOP) is considered an alternative to 8-methoxypsoralen (8-MOP) for photochemotherapy of psoriasis." | 9.07 | A reappraisal of the use of 5-methoxypsoralen in the therapy of psoriasis. ( Calzavara-Pinton, P; Carlino, A; De Panfilis, G; Honigsmann, H; Ortel, B, 1992) |
| "In a randomized, double-blind comparative study 60 patients with severe, widespread psoriasis were treated either with photochemotherapy (PUVA) alone or in combination with acitretin." | 9.07 | Photochemotherapy for severe psoriasis without or in combination with acitretin: a randomized, double-blind comparison study. ( Fritsch, P; Geiger, JM; Guggenbichler, A; Hönigsmann, H; Tanew, A, 1991) |
| "Because oral methoxsalen and UV-A radiation (PUVA) therapy is mutagenic, concern exists about the potential for teratogenic effects resulting from the use of this therapy at the time of conception and during pregnancy." | 9.07 | Outcomes of pregnancies among women and partners of men with a history of exposure to methoxsalen photochemotherapy (PUVA) for the treatment of psoriasis. ( Lange, R; Stern, RS, 1991) |
| "Photochemotherapeutic treatment of psoriasis with trioxsalen baths (0." | 9.04 | Treatment of psoriasis with trioxsalen baths and dysprosium lamps. ( Alsins, J; Fischer, T, 1976) |
| "Fifty-one patients with psoriasis were treated with oral methoxsalen and sunlight exposure." | 9.04 | Photochemotherapy of psoriasis using methoxsalen and sunlight. A controlled study. ( Fitzpatrick, TB; Kingsbury, T; Parrish, JA; White, AD; Zahar, M, 1977) |
| "Comparable lesions in 16 patients with chronic plaque psoriasis were treated with clobetasol propionate or placebo ointments for 1 week before beginning photochemotherapy." | 9.04 | Psoriasis treated with clobetasol propionate and photochemotherapy. ( Gould, PW; Wilson, L, 1978) |
| "Topical methoxsalen photochemotherapy has been assessed in 22 patients suffering from recalcitrant palmoplantar pustulosis or psoriasis predominantly involving the hands and feet." | 9.04 | Topical methoxsalen photochemotherapy in the treatment of palmoplantar pustulosis and psoriasis. ( Black, MM; Harper, JI; Ralfs, IG; Wilkinson, JD, 1979) |
| " Twelve patients with symmetrical plaque-type psoriasis were given PUVA on one side of the body and PUVA plus betamethasone valerate on the other side in a paired comparison study." | 9.04 | Combination therapy for psoriasis. Psoralens plus long-wave ultraviolet radiation with betamethasone valerate. ( Hanke, CW; Roenigk, HH; Steck, WD, 1979) |
| "5-Methoxypsoralen, a naturally occurring linear furocoumarin, has been successfully used in combination with ultraviolet (UV) A irradiation [psoralen plus UV (PUVA)] to manage psoriasis and vitiligo." | 8.80 | 5-Methoxypsoralen. A review of its effects in psoriasis and vitiligo. ( Goa, KL; McNeely, W, 1998) |
| "Eight patients with psoriasis were given 200 mg caffeine orally with or without 1." | 7.69 | Inhibition of caffeine metabolism by 5-methoxypsoralen in patients with psoriasis. ( Agache, P; Bechtel, PR; Bechtel, Y; Bendriss, A; Bendriss, EK; Humbert, PH; Magnette, J; Paintaud, G, 1996) |
| "Photochemotherapy with oral methoxsalen (psoralen) and ultraviolet A radiation (PUVA) is an effective treatment for psoriasis." | 7.69 | Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA). The PUVA Follow-Up Study. ( Nichols, KT; Stern, RS; Väkevä, LH, 1997) |
| "After oral intake, 5-methoxypsoralen (5-MOP) is as effective as 8-MOP for PUVA therapy for psoriasis, with a lower incidence of acute cutaneous side effects." | 7.69 | Bath-5-methoxypsoralen-UVA therapy for psoriasis. ( Calzavara-Pinton, PG; Carlino, A; De Panfilis, G; Zane, C, 1997) |
| "Three derivatives of angelicin (1) [4'-methyl-, 4,4'-dimethyl-, and 4',5-dimethylangelicin (2a-c)] have been prepared with the aim of obtaining new agents for the photochemotherapy of psoriasis." | 7.66 | 4'-Methylangelicins: new potential agents for the photochemotherapy of psoriasis. ( Baccichetti, F; Bordin, F; Carlassare, F; Cristofolini, M; Dall'Acqua, F; Guiotto, A; Pastorini, G; Recchia, G; Rodighiero, P; Tamaro, M; Vedaldi, D, 1983) |
| "In the treatment of psoriasis with topically applied methoxsalen, the patient is exposed to long-wave UV (UV-A) energy two hours after the application of methoxsalen." | 7.66 | Topical methoxsalen followed immediately by long-wave UV irradiation. A preliminary report on the treatment of psoriasis. ( Danno, K; Horio, T; Ishida, H; Toda, K, 1982) |
| "In 1974 a new therapy that employs methoxsalen and ultraviolet A irradiation (PUVA) was introduced as an outpatient treatment for severe psoriasis." | 7.66 | Effect of methoxsalen photochemotherapy on cost of treatment for psoriasis. An example of technological assessment. ( Bleich, HL; Fitzpatrick, TB; Kleinerman, RA; Parrish, JA; Stern, RS; Thibodeau, LA, 1981) |
| "Fourteen patients with chronic plaque-type psoriasis involving the palms and soles and 14 patients with palmoplantar vesiculopustular dermatosis, including three cases of localized pustular psoriasis, were treated with topical application of methoxsalen, followed by exposure to long-wave ultraviolet energy (topical PUVA)." | 7.66 | Treatment of palmoplantar psoriasis with topical methoxsalen plus long-wave ultraviolet light. ( Abel, EA; Farber, EM; Goldberg, LH, 1980) |
| "Elevated uric acid serum levels are a frequent finding in psoriasis and, despite some reports to the contrary, it is generally believed that an association does exist between hyperuricemia and psoriasis." | 7.66 | Serum uric acid levels in untreated and PUVA-treated patients with psoriasis. ( Brenner, W; Gschnait, F, 1979) |
| "Precipitation of generalized pustular psoriasis was manifested in a patient with previously stable psoriasis vulgaris following lithium carbonate therapy for manic-depressive psychosis." | 7.66 | Generalized pustular psoriasis precipitated by lithium carbonate. ( Lowe, NJ; Ridgway, HB, 1978) |
| "Seventy-four patients with psoriasis were treated using a trioxsalen bath (50 mg/150 l of water) and long wave ultraviolet light (UVA) given in an ordinary PUVA-cabin." | 7.66 | Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis. ( Hannuksela, M; Karvonen, J, 1978) |
| " This study describes the efficacy of photochemotherapy, using orally administered methoxsalen and long-wave ultraviolet light in 91 patients with severe, generalized psoriasis." | 7.65 | Photochemotherapy for psoriasis with orally administered methoxsalen. ( Fitzpatrick, TB; Gilchrest, B; Gschnait, F; Hönigsmann, H; Parrish, JA; Pathak, MA; Tannenbaum, L; Wolff, KW, 1976) |
| "Thirty patients with recalcitrant psoriasis were treated with topical methoxsalen and blacklight (UVA)." | 7.65 | Topical methoxsalen and blacklight in the treatment of psoriasis. ( Kaidbey, KM; Kligman, AM; Petrozzi, JW, 1977) |
| " With a new liquid preparation of 5-MOP we have now extended our earlier investigation on a larger clinical scale and have correlated the clinical response with the bioavailability of the drug." | 6.66 | 5-Methoxypsoralen (Bergapten) for photochemotherapy. Bioavailability, phototoxicity, and clinical efficacy in psoriasis of a new drug preparation. ( Hönigsmann, H; Ortel, B; Rappersberger, K; Tanew, A, 1988) |
| " The UVB erythema response of normal skin served as the guide to light dosage in the same manner as administration of the Goeckerman regimen." | 5.26 | Topical methoxsalen administration and sunlamp fluorescent irradiation in psoriasis. ( Barton, JO; de los Reyes, O; Kligman, A; Petrozzi, JW, 1979) |
| "Combination of topical methoxsalen and narrowband ultraviolet B (NBUVB) was shown to be more effective than NBUVB alone in treating plaque-type psoriasis." | 5.15 | Comparison of topical 8-methoxypsoralen and narrowband ultraviolet B with narrowband ultraviolet B alone in treatment-resistant sites in plaque-type psoriasis: a placebo-controlled study. ( Daneshpazhooh, M; Ehsani, AH; Ghaninejad, H; Hosseini, SH; Kiani, A; Noormohammadpoor, P, 2011) |
| "Our data indicate that in bath-PUVA treatment the use of a high (5 mg/L) methoxsalen concentration is substantially more effective in clearing chronic plaque-type psoriasis than a low (1 mg/L) concentration." | 5.12 | Randomized, double-blind comparison of 1 mg/L versus 5 mg/L methoxsalen bath-PUVA therapy for chronic plaque-type psoriasis. ( Hönigsmann, H; Konschitzky, R; Seeber, A; Tanew, A; Treitl, C; Vongthongsri, R, 2006) |
| "A bilateral comparison study of the therapeutic effects of broad-band ultraviolet (UBV) (FS-40 Sunlamp bulbs) radiation versus UVB radiation plus methoxsalen was conducted in patients with psoriasis." | 5.08 | Combination of methoxsalen and ultraviolet B (UVB) versus UVB radiation alone in treatment of psoriasis: a bilateral comparison study. ( Morison, WL, 1995) |
| "Thirty-eight patients with plaque-type psoriasis were enrolled in a double-blind psoralen plus ultraviolet A (PUVA) treatment study comparing the efficacy and side effects of 5-methoxypsoralen (5-MOP) and 8-methoxypsoralen (8-MOP)." | 5.07 | Treatment of psoriasis with psoralens and ultraviolet A. A double-blind comparison of 8-methoxypsoralen and 5-methoxypsoralen. ( Berg, M; Ros, AM, 1994) |
| "5-methoxypsoralen (5-MOP) is considered an alternative to 8-methoxypsoralen (8-MOP) for photochemotherapy of psoriasis." | 5.07 | A reappraisal of the use of 5-methoxypsoralen in the therapy of psoriasis. ( Calzavara-Pinton, P; Carlino, A; De Panfilis, G; Honigsmann, H; Ortel, B, 1992) |
| "In a randomized, double-blind comparative study 60 patients with severe, widespread psoriasis were treated either with photochemotherapy (PUVA) alone or in combination with acitretin." | 5.07 | Photochemotherapy for severe psoriasis without or in combination with acitretin: a randomized, double-blind comparison study. ( Fritsch, P; Geiger, JM; Guggenbichler, A; Hönigsmann, H; Tanew, A, 1991) |
| "Because oral methoxsalen and UV-A radiation (PUVA) therapy is mutagenic, concern exists about the potential for teratogenic effects resulting from the use of this therapy at the time of conception and during pregnancy." | 5.07 | Outcomes of pregnancies among women and partners of men with a history of exposure to methoxsalen photochemotherapy (PUVA) for the treatment of psoriasis. ( Lange, R; Stern, RS, 1991) |
| "Successful results have been reported for bath-psoralens plus ultraviolet A (PUVA) treatment of psoriasis with the use of either a low-sensitizing psoralen (methoxsalen) or a high-sensitizing psoralen (trioxsalen), but no evidence has been presented that phototoxicity would be a prerequisite for antipsoriatic activity of these treatments." | 5.06 | Antipsoriatic, erythematogenic, and Langerhans cell marker depleting effect of bath-psoralens plus ultraviolet A treatment. Comparison of 8-methoxypsoralen and trimethylpsoralen photosensitization. ( Jansén, CT; Koulu, LM, 1988) |
| "Photochemotherapeutic treatment of psoriasis with trioxsalen baths (0." | 5.04 | Treatment of psoriasis with trioxsalen baths and dysprosium lamps. ( Alsins, J; Fischer, T, 1976) |
| "Fifty-one patients with psoriasis were treated with oral methoxsalen and sunlight exposure." | 5.04 | Photochemotherapy of psoriasis using methoxsalen and sunlight. A controlled study. ( Fitzpatrick, TB; Kingsbury, T; Parrish, JA; White, AD; Zahar, M, 1977) |
| "Comparable lesions in 16 patients with chronic plaque psoriasis were treated with clobetasol propionate or placebo ointments for 1 week before beginning photochemotherapy." | 5.04 | Psoriasis treated with clobetasol propionate and photochemotherapy. ( Gould, PW; Wilson, L, 1978) |
| "Topical methoxsalen photochemotherapy has been assessed in 22 patients suffering from recalcitrant palmoplantar pustulosis or psoriasis predominantly involving the hands and feet." | 5.04 | Topical methoxsalen photochemotherapy in the treatment of palmoplantar pustulosis and psoriasis. ( Black, MM; Harper, JI; Ralfs, IG; Wilkinson, JD, 1979) |
| " Twelve patients with symmetrical plaque-type psoriasis were given PUVA on one side of the body and PUVA plus betamethasone valerate on the other side in a paired comparison study." | 5.04 | Combination therapy for psoriasis. Psoralens plus long-wave ultraviolet radiation with betamethasone valerate. ( Hanke, CW; Roenigk, HH; Steck, WD, 1979) |
| "5-Methoxypsoralen, a naturally occurring linear furocoumarin, has been successfully used in combination with ultraviolet (UV) A irradiation [psoralen plus UV (PUVA)] to manage psoriasis and vitiligo." | 4.80 | 5-Methoxypsoralen. A review of its effects in psoriasis and vitiligo. ( Goa, KL; McNeely, W, 1998) |
| "A child was treated from age 18 months to 8 years with oral methoxsalen and ultraviolet A radiation (PUVA) for refractory psoriasis." | 4.79 | Therapy with orally administered methoxsalen and ultraviolet A radiation during childhood increases the risk of basal cell carcinoma. The PUVA Follow-up Study. ( Nichols, KT; Stern, RS, 1996) |
| "The combination of methoxsalen and long-wave UV radiation (UV-A) is being used on a large scale in clinical practice to treat a variety of dermatoses, particularly psoriasis." | 4.76 | Mutagenicity and carcinogenicity of methoxsalen plus UV-A. ( Roelandts, R, 1984) |
| "The effects of 8-Methoxypsoralen plus ultraviolet A (PUVA) or ultraviolet B (UVB) alone on imiquimod-induced psoriasis were examined in a mouse model." | 3.88 | 8-Methoxypsoralen Plus Ultraviolet A Reduces the Psoriatic Response to Imiquimod in a Murine Model. ( Brüne, B; Kenner, L; Ringel, C; Schlederer, M; Shirsath, N; Tangermann, S; Wagner, K; Wolf, P, 2018) |
| "Acitretin is currently used alone or combined with PUVA (psoralen + UVA) or with narrow-band ultraviolet B (NBUVB), to treat moderate and severe psoriasis." | 3.79 | Cytotoxic and genotoxic effects of acitretin, alone or in combination with psoralen-ultraviolet A or narrow-band ultraviolet B-therapy in psoriatic patients. ( Bronze-da-Rocha, E; Custódio, JB; Fernandes, JC; Figueiredo, A; Moreiras, A; Oliveira, H; Rocha-Pereira, P; Santos-Silva, A; Silva, FS, 2013) |
| "5-methoxypsoralen (bergapten) has been used in the treatment of psoriasis and vitiligo, and as a sun tanning accelerator." | 3.77 | Percutaneous penetration of 5-methoxypsoralen in rhesus monkeys. ( Konda, S; Maibach, HI, 2011) |
| "Broad-band UVB alone or in combination with different topical drugs (anthralin, calcipotriol), systemic PUVA and bath-PUVA therapy are very effective and well-established treatment modalities for psoriasis." | 3.71 | Phototherapy of psoriasis: comparative experience of different phototherapeutic approaches. ( Ackermann, G; Eholzer, C; Karrer, S; Landthaler, M; Szeimies, RM, 2001) |
| "Oral methoxsalen (psoralen) and ultraviolet A radiation (PUVA) is a highly effective therapy for psoriasis and many other skin conditions." | 3.71 | The risk of melanoma in association with long-term exposure to PUVA. ( Stern, RS, 2001) |
| "A 55-year-old woman with psoriasis vulgaris was treated with oral 5-methoxypsoralen and UVA photochemotherapy." | 3.70 | Hepatitis from 5-methoxypsoralen occurring in a patient with previous flucloxacillin hepatitis. ( Cooper, A; Stephens, RB, 1999) |
| "Bath PUVA has been shown to be an effective alternative treatment for psoriasis with fewer systemic side effects than oral methoxsalen (8-MOP)." | 3.69 | Treatment of psoriasis with polyethylene sheet bath PUVA. ( Christophers, E; Streit, V; Wiedow, O, 1996) |
| "Eight patients with psoriasis were given 200 mg caffeine orally with or without 1." | 3.69 | Inhibition of caffeine metabolism by 5-methoxypsoralen in patients with psoriasis. ( Agache, P; Bechtel, PR; Bechtel, Y; Bendriss, A; Bendriss, EK; Humbert, PH; Magnette, J; Paintaud, G, 1996) |
| "5-Methoxypsoralen is often substituted for 8-methoxypsoralen in the photochemotherapy of psoriasis even though the nature of the resulting photadducts in cellular DNA has not been determined." | 3.69 | 5-Methoxypsoralen photoadduct formation: conversion of monoadducts to crosslinks. ( Amici, LA; Gasparro, FP, 1995) |
| "Photochemotherapy with oral methoxsalen (psoralen) and ultraviolet A radiation (PUVA) is an effective treatment for psoriasis." | 3.69 | Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA). The PUVA Follow-Up Study. ( Nichols, KT; Stern, RS; Väkevä, LH, 1997) |
| "After oral intake, 5-methoxypsoralen (5-MOP) is as effective as 8-MOP for PUVA therapy for psoriasis, with a lower incidence of acute cutaneous side effects." | 3.69 | Bath-5-methoxypsoralen-UVA therapy for psoriasis. ( Calzavara-Pinton, PG; Carlino, A; De Panfilis, G; Zane, C, 1997) |
| "Three biopsies of normal skin and 15 biopsies collected from patients with psoriasis vulgaris were analyzed for the expression of the 50 kd cytokeratin using direct immunofluorescence and ABC technique before and after local treatment with anthralin 0." | 3.68 | Immunohistochemical study on the pattern of 50 kd cytokeratin in psoriasis. ( Fedi, AM; Leoncini, P; Lotti, T; Meo, AL; Rizzo, A, 1992) |
| " It is advocated as a means of determining an individual's relative risk of skin tumors and has been used to determine the initial therapeutic dose of UV radiation for UV-B phototherapy or oral methoxsalen photochemotherapy (PUVA) for psoriasis." | 3.67 | Skin typing for assessment of skin cancer risk and acute response to UV-B and oral methoxsalen photochemotherapy. ( Momtaz, K; Stern, RS, 1984) |
| "Therapy with methoxsalen and type A (long-wavelength) ultraviolet radiation (PUVA) has recently become a common method of treating psoriasis and other dermatologic conditions." | 3.67 | Lens opacities appearing during therapy with methoxsalen and long-wavelength ultraviolet radiation. ( Grenier, R; Lafond, G; Roy, PE, 1984) |
| "A patient with epilepsy and psoriasis in phenytoin therapy was treated with PUVA with no effect at all." | 3.67 | Interaction between 8-methoxypsoralen and phenytoin. Consequence for PUVA therapy. ( Hueg, B; Staberg, B, 1985) |
| "The acute effect of a single oral dose of methoxsalen on the pharmacokinetics of caffeine was investigated in five nonsmoking volunteers with psoriasis." | 3.67 | Methoxsalen is a potent inhibitor of the metabolism of caffeine in humans. ( Camisa, C; Cheney, P; Gerber, N; Mays, DC; Nawoot, S; Pacula, CM, 1987) |
| "5-Methoxypsoralen (5-MOP) (Psoraderm 5) tablets obtained from France and 5-MOP micronized in capsules (manufactured in our pharmacy department) were administered to seven psoriasis patients in a 1." | 3.67 | Comparison of bioavailability and phototoxicity of two oral preparations of 5-methoxypsoralen. ( Cormane, RH; Siddiqui, AH; Stolk, LM; Westerhof, W, 1985) |
| "Psoralen photoproducts were identified in association with cataracts in a psoriatic patient several years after oral methoxsalen plus ultraviolet A light (PUVA) therapy." | 3.67 | Lenticular psoralen photoproducts and cataracts of a PUVA-treated psoriatic patient. ( Anderson, TF; Lerman, S; Wong, JM; Wong, RC; Woo, TY, 1985) |
| "Three derivatives of angelicin (1) [4'-methyl-, 4,4'-dimethyl-, and 4',5-dimethylangelicin (2a-c)] have been prepared with the aim of obtaining new agents for the photochemotherapy of psoriasis." | 3.66 | 4'-Methylangelicins: new potential agents for the photochemotherapy of psoriasis. ( Baccichetti, F; Bordin, F; Carlassare, F; Cristofolini, M; Dall'Acqua, F; Guiotto, A; Pastorini, G; Recchia, G; Rodighiero, P; Tamaro, M; Vedaldi, D, 1983) |
| "The sodium lauryl (dodecyl) sulfate polyacrylamide gel electrophoresis (SLS PAGE) patterns of keratin polypeptides were followed in 29 patients with psoriasis who were treated with middle wavelength ultraviolet (UV) radiation (UV B), oral methoxsalen, and long wavelength UV radiation (PUVA), or systemic antipsoriatic therapy." | 3.66 | Effect of therapy on keratin polypeptide profiles of psoriatic epidermis. ( Baden, HP; LeVine, MJ; McGilvray, N, 1980) |
| "To determine the potentially adverse effects of photoactive medications taken in conjunction with oral methoxsalen photochemotherapy (PUVA) for psoriasis, we studied the incidence of phototoxic reactions in 1,125 patients treated with PUVA at 15 centers." | 3.66 | Phototoxic reactions to photoactive drugs in patients treated with PUVA. ( Bleich, HL; Fitzpatrick, TB; Kleinerman, RA; Parrish, JA; Stern, RS, 1980) |
| "In the treatment of psoriasis with topically applied methoxsalen, the patient is exposed to long-wave UV (UV-A) energy two hours after the application of methoxsalen." | 3.66 | Topical methoxsalen followed immediately by long-wave UV irradiation. A preliminary report on the treatment of psoriasis. ( Danno, K; Horio, T; Ishida, H; Toda, K, 1982) |
| "In 1974 a new therapy that employs methoxsalen and ultraviolet A irradiation (PUVA) was introduced as an outpatient treatment for severe psoriasis." | 3.66 | Effect of methoxsalen photochemotherapy on cost of treatment for psoriasis. An example of technological assessment. ( Bleich, HL; Fitzpatrick, TB; Kleinerman, RA; Parrish, JA; Stern, RS; Thibodeau, LA, 1981) |
| "Fourteen patients with chronic plaque-type psoriasis involving the palms and soles and 14 patients with palmoplantar vesiculopustular dermatosis, including three cases of localized pustular psoriasis, were treated with topical application of methoxsalen, followed by exposure to long-wave ultraviolet energy (topical PUVA)." | 3.66 | Treatment of palmoplantar psoriasis with topical methoxsalen plus long-wave ultraviolet light. ( Abel, EA; Farber, EM; Goldberg, LH, 1980) |
| "A 59-year-old white woman with long-standing psoriasis, who had a damaged liver from methotrexate, developed a toxic hepatitis while on oral methoxsalen photochemotherapy (PUVA)." | 3.66 | Toxic hepatitis from oral methoxsalen photochemotherapy (PUVA). ( Pariser, DM; Wyles, RJ, 1980) |
| "Elevated uric acid serum levels are a frequent finding in psoriasis and, despite some reports to the contrary, it is generally believed that an association does exist between hyperuricemia and psoriasis." | 3.66 | Serum uric acid levels in untreated and PUVA-treated patients with psoriasis. ( Brenner, W; Gschnait, F, 1979) |
| "The excretion of the specific melanocytic metabolite 5-S-cysteinyldopa was studied in patients with psoriasis treated by 8-methoxypsoralen and UVA light." | 3.66 | 5-S-cysteinyldopa excretion after treatment with 8-methoxypsoralen and UVA light. ( Agrup, G; Hansson, C; Rorsman, H; Rosengren, E; Tegner, E, 1978) |
| "High intensity long ultraviolet light (UV-A) systems along with oral methoxsalen (8-methoxypsoralen [8-MOP]) have been dramatically successful in clearing long-standing psoriasis." | 3.66 | Photochemotherapy of psoriasis (PUVA) without specialized equipment. ( Kligman, AM; Petrozzi, JW, 1978) |
| "Precipitation of generalized pustular psoriasis was manifested in a patient with previously stable psoriasis vulgaris following lithium carbonate therapy for manic-depressive psychosis." | 3.66 | Generalized pustular psoriasis precipitated by lithium carbonate. ( Lowe, NJ; Ridgway, HB, 1978) |
| "Seventy-four patients with psoriasis were treated using a trioxsalen bath (50 mg/150 l of water) and long wave ultraviolet light (UVA) given in an ordinary PUVA-cabin." | 3.66 | Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis. ( Hannuksela, M; Karvonen, J, 1978) |
| "Photochemotherapy for psoriasis combining orally administered methoxsalen and long-wave ultraviolet (UVA) light was used in 186 patients with severe psoriasis." | 3.65 | Photochemotherapy for psoriasis. ( Martin, JS; Roenigk, HH, 1977) |
| "From an examination of all possible methods for the treatment of psoriasis and the therapeutic results obtained with them, the author emphasizes the outstanding efficacy of a method for the treatment of psoriasis only recent described in the medical literature, which consists of a combination of methoxsalen by mouth and longwave ultraviolet light." | 3.65 | [Treatment of psoriasis (author's transl)]. ( Ormea, F, 1976) |
| " This study describes the efficacy of photochemotherapy, using orally administered methoxsalen and long-wave ultraviolet light in 91 patients with severe, generalized psoriasis." | 3.65 | Photochemotherapy for psoriasis with orally administered methoxsalen. ( Fitzpatrick, TB; Gilchrest, B; Gschnait, F; Hönigsmann, H; Parrish, JA; Pathak, MA; Tannenbaum, L; Wolff, KW, 1976) |
| "Thirty patients with recalcitrant psoriasis were treated with topical methoxsalen and blacklight (UVA)." | 3.65 | Topical methoxsalen and blacklight in the treatment of psoriasis. ( Kaidbey, KM; Kligman, AM; Petrozzi, JW, 1977) |
| "Photochemotherapy (PUVA) with oral methoxsalen and UV-A was instituted in 8 patients with generalized pustular psoriasis (von Zumbusch)." | 3.65 | Photochemotherapy for pustular psoriasis (von Zumbusch). ( Gschnait, F; Hönigsmann, H; Konrad, K; Wolff, K, 1977) |
| "Plaque psoriasis is an inflammatory disease affecting approximately 2% of the population." | 2.78 | Efficacy of bath psoralen plus ultraviolet A (PUVA) vs. system PUVA in psoriasis: a prospective, open, randomized, multicentre study. ( Berneburg, M; Eberlein, B; Guenova, E; Herzinger, T; Hoetzenecker, W; Maetzke, J; Meisner, C; Rampf, J; Rocken, M; Schaefer, T; Scharffetter-Kochanek, K, 2013) |
| " The two different methods of dosing were used on consecutive treatment days and the plasma 8-MOP concentration was measured on each occasion 2 h after ingestion of the crystalline form of 8-MOP, given to the nearest 10 mg." | 2.68 | Calculation of 8-methoxypsoralen dose according to body surface area in PUVA treatment. ( Diffey, BL; Farr, PM; Sakuntabhai, A, 1995) |
| "PUVA treatment of psoriasis is usually given with broad-band fluorescent UVA lamps." | 2.68 | Comparison of psoralen-UVB and psoralen-UVA photochemotherapy in the treatment of psoriasis. ( de Berker, DA; Diffey, BL; Farr, PM; Matthews, JN; Sakuntabhai, A, 1997) |
| "Thirty-nine patients with psoriasis undergoing PUVA participated in a prospective double-blind study of acute non-phototoxic adverse effects comparing the liquid formulations of 8-methoxypsoralen (0." | 2.67 | Liquid formulations of 8-methoxypsoralen (8-MOP) and 5-MOP: a prospective double-blind crossover assessment of acute non-phototoxic adverse effects. ( Ferguson, J; George, SA, 1992) |
| " With a new liquid preparation of 5-MOP we have now extended our earlier investigation on a larger clinical scale and have correlated the clinical response with the bioavailability of the drug." | 2.66 | 5-Methoxypsoralen (Bergapten) for photochemotherapy. Bioavailability, phototoxicity, and clinical efficacy in psoriasis of a new drug preparation. ( Hönigsmann, H; Ortel, B; Rappersberger, K; Tanew, A, 1988) |
| "A bioavailability study was performed with a pill containing microcrystalline 8-MOP and a soft gelatine capsule containing dissolved 8-MOP in 35 patients receiving PUVA treatment." | 2.66 | Bioavailability study of two different 8-methoxypsoralen (8-MOP) preparations in patients receiving PUVA therapy. ( Hueg, B; Nørgaard, M; Staberg, B, 1985) |
| " 2 Bioavailability and serum peak concentrations were significantly higher for Maladinine in all patients and the MPD value favoured Maladinine in 5 of the 8 patients." | 2.65 | Difference in bioavailability between two brands of 8-methoxypsoralen and its impact on the clinical response in psoriatic patients. ( De Wolff, FA; Herfst, MJ, 1982) |
| "No increased risk of skin cancer was evidenced in the four studies specifically assessing the potential carcinogenic risk of NB-UVB." | 2.48 | Carcinogenic risks of psoralen UV-A therapy and narrowband UV-B therapy in chronic plaque psoriasis: a systematic literature review. ( Aractingi, S; Archier, E; Aubin, F; Bachelez, H; Castela, E; Cribier, B; Devaux, S; Gallini, A; Joly, P; Jullien, D; Le Maître, M; Misery, L; Ortonne, JP; Paul, C; Richard, MA, 2012) |
| "Three phototherapeutic regimens with photosensitization are now used in dermatology: PUVA (psoralen + UVA), TUV (crude coaltar + UV), PRT (phototherapy with hematoporphyrin derivative)." | 2.37 | [Problems posed by the therapeutic use of photosensitizers in dermatology]. ( Amblard, P; Beani, JC; Reymond, JL, 1986) |
| " Following the dosage parameters toxic side effects were rare and reversible." | 2.36 | [Oral photochemotherapy (author's transl)]. ( Gschnait, F, 1977) |
| "Psoriasis is a chronic inflammatory skin disorder mediated by cross-talk occurring between epidermal keratinocytes, dermal vascular cells and immunocytes." | 1.40 | hsa-miR-4516 mediated downregulation of STAT3/CDK6/UBE2N plays a role in PUVA induced apoptosis in keratinocytes. ( Chowdhari, S; Saini, N, 2014) |
| "Psoriasis and eczema are common dermatological diseases that occur with approximately equal frequency in men and in women." | 1.35 | "The Laundry Bag Project"--unequal distribution of dermatological healthcare resources for male and female psoriatic patients in Sweden. ( Evengård, B; Nyberg, F; Osika, I, 2008) |
| " Pharmacokinetic behaviour of 8-MOP was examined in serum; samples were analysed by HPLC." | 1.31 | Pharmacokinetic behaviour of sublingually administered 8-methoxypsoralen for PUVA therapy. ( Langguth, P; Panizzon, RG; Shephard, SE, 2001) |
| "Four consecutive AIDS patients with psoriasis and CD4 count lower than 20/mm3 were treated with 8-methoxypsoralen and UVA (PUVA)." | 1.30 | Impact of PUVA therapy on HIV viremia: a pilot study. ( Krischer, J; Lemonnier, E; Pechère, M; Perrin, L; Saurat, JH; Yerly, S, 1997) |
| " Observations on the time-course and dose-response characteristics of PUVA erythema suggest that larger doses of UVA could be used safely, provided that the frequency of PUVA treatment is reduced." | 1.29 | Response of psoriasis to twice weekly PUVA. ( Farr, PM; Sakuntabhai, A; Sharpe, GR, 1993) |
| " The erythema responses were judged visually, and also measured using a reflectance instrument in order to construct dose-response curves." | 1.29 | PUVA erythemal sensitivity depends on plasma psoralen concentration and UVA sensitivity. ( Diffey, BL; Farr, PM; Sakuntabhai, A, 1993) |
| "One psoriatic patient developed Bowen's disease." | 1.29 | Cutaneous carcinoma and PUVA lentigines in Thai patients treated with oral PUVA. ( Gritiyarangsan, P; Kullavanijaya, P; Rungrairatanaroj, P; Sindhavananda, J, 1995) |
| " Single oral doses of 14C-5-methoxypsoralen (5-MOP) to human subjects (50 mg), rats (1 mg/kg) and dogs (1 mg/kg) were fairly well absorbed but subjected to extensive first-pass metabolism, at least in rat and human." | 1.28 | Metabolism of the anti-psoriatic agent 5-methoxypsoralen in humans: comparison with rat and dog. ( Chasseaud, LF; Forlot, P; John, BA; Wood, SG, 1992) |
| " The resulting erythema was measured objectively 72 h after irradiation and dose-response curves for psoralen-UVA erythema were constructed." | 1.28 | The relationship between plasma psoralen concentration and psoralen-UVA erythema. ( Cox, NH; Diffey, BL; Farr, PM; Fisher, C; Mclelland, J, 1991) |
| " Whether concomitant retinoid administration influences the bioavailability of 8-MOP was considered an interesting question." | 1.28 | [Influence of retinoids on the bioavailability of methoxy-8-psoralen]. ( Amblard, P; Beani, JC; Beriel, H; Berthod, F; Boitard, M; Bonnot, D; Reymond, JL, 1991) |
| "In order to register the inter- and intraindividual variability of serum levels of 8-methoxypsoralen (MOP) (Oxsoralen, n = 12; Geroxalen, n = 46; Mopsoralen, n = 30), we investigated a total of 1,276 serum samples obtained at 11 patient appointments over 8 h in 88 patients and compared the individual serum concentrations - time curves with the pharmacokinetic parameters Cmax (maximal serum concentration) on the time tmax, as well as the AUC value (area under the curve) as a parameter of bioavailability." | 1.28 | [Pharmacokinetic comparison of 3 8-methoxypsoralen preparations and clinical aspects]. ( Haustein, UF; Meyer, FP; Quednow, B; Walther, T, 1990) |
| " The smallest ultraviolet radiation doses to produce erythema (minimal erythema dose and minimal phototoxic dose, respectively) were recorded and dose-response curves were constructed for UVB (24 hours after irradiation) and PUVA (48 hours) using objective measurement." | 1.28 | A comparison of the dose-response relationship for psoralen-UVA erythema and UVB erythema. ( Cox, NH; Diffey, BL; Farr, PM, 1989) |
| "Ten patients with chronic widespread plaque psoriasis, all of whom had previously completely cleared and suffered a subsequent widespread relapse after conventional PUVA therapy, were treated with a modified UVA dosage schedule, with psoralen formulation and dosage unchanged." | 1.28 | A modified dosage schedule for increased efficiency in PUVA treatment of psoriasis. ( Carabott, FM; Hawk, JL, 1989) |
| " The range of maximum UVA dosage per treatment was 3." | 1.28 | Palmoplantar psoriasis: experience with 8-methoxypsoralen soaks plus ultraviolet A with the use of a high-output metal halide device. ( Coleman, WR; David, M; Halder, RM; Lowe, NJ, 1989) |
| " In one patient who showed a lower absorption rate of 8-MOP plasma levels varied from 0-126 ng/ml." | 1.26 | Intraindividual variations of 8-methoxypsoralen plasma levels. ( Korting, HC; Schäfer-Korting, M, 1982) |
| "Plasma and skin blister fluid levels of 8-MOP are determined 2 h following oral administration of 40-60 mg 8-MOP." | 1.26 | Determination of 8-methoxypsoralen levels in plasma and skin suction blister fluid by a new sensitive fluorodensitometric method. ( Korting, HC; Mutschler, E; Roser-Maass, E; Schäfer-Korting, M, 1982) |
| " The advantages of this modality include noninvolvement of the upper gastrointestinal tract, high bioavailability of psoralen, peak levels at a predictable time, and rapid elimination of the drug." | 1.26 | Microenema of 8-methoxypsoralen in photochemotherapy of psoriasis. ( Cormane, RH; Kammeijer, A; Korthals Altes-Levij van Vinninghe, HR; Siddiqui, AH; Stolk, L, 1982) |
| "Recently, psoriasis has been shown to respond favorably to PUVA treatment, i." | 1.26 | [PUVA treatment and the problem of ocular damage (author's transl)]. ( Koch, HR; Lerman, S, 1981) |
| " The 8-methoxypsoralen dosage was approximately 0." | 1.26 | Treatment of resistant psoriasis with oral 8-methoxypsoralen and longwave ultraviolet light (PUVA). A treatment schedule and a follow-up study. ( Bro-Jorgensen, A; Howitz, J; Weismann, K, 1977) |
| "Multiple lesions of Bowen's disease and squamous cell carcinoma on the penis and pubic areas developed in a 32-year-old patient with psoriasis who was undergoing treatment with psoralen and long-wave ultraviolet radiation (PUVA)." | 1.26 | Bowen's disease and squamous cell carcinoma. Occurrence in a patient with psoriasis after topical, systemic, and PUVA therapy. ( Tam, DW; Urbach, F; Van Scott, EJ, 1979) |
| " The UVB erythema response of normal skin served as the guide to light dosage in the same manner as administration of the Goeckerman regimen." | 1.26 | Topical methoxsalen administration and sunlamp fluorescent irradiation in psoriasis. ( Barton, JO; de los Reyes, O; Kligman, A; Petrozzi, JW, 1979) |
| "Patients treated for psoriasis with 8-MOP show concentrations of 10(-6)-10(-7) M." | 1.26 | Toxic effects of 8-methoxypsoralen on lymphocyte division. ( Wettermark, G; Wulf, HC, 1977) |
| "The results of the first six months of treatment of psoriasis with photochemotherapy in the Skin and Cancer Foundation's clinic resulted in 30 out of 53 patients being completely clear of psoriasis lesions, 14 showing progressive improvement (and subsequently clearing), four failures, and five withdrawals." | 1.26 | Photochemotherapy in psoriasis: the first six months in Australia. ( King, R; O'Brien, H; Paver, K; Poyzer, K, 1979) |
| " However, with high dosage of UVA (5 J/cm(2)) with and without 8-MOP still 25-30% cells migrated through the filters." | 1.26 | Leukocyte chemotaxis after in vitro treatment with 8-methoxypsoralen and UVA. ( Christophers, E; Langner, A, 1977) |
| "The possible methods of treating psoriasis and results obtained are reviewed and the superior effectiveness of an approach reported in recent literature, an association of methoxalene per os and broad ultraviolet rays, is pointed out." | 1.26 | [Therapy of psoriasis]. ( Ormea, F, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 339 (71.82) | 18.7374 |
| 1990's | 80 (16.95) | 18.2507 |
| 2000's | 29 (6.14) | 29.6817 |
| 2010's | 23 (4.87) | 24.3611 |
| 2020's | 1 (0.21) | 2.80 |
| Authors | Studies |
|---|---|
| Hansen, JB | 1 |
| Bjerring, P | 1 |
| Buchardt, O | 1 |
| Ebbesen, P | 1 |
| Kanstrup, A | 1 |
| Karup, G | 1 |
| Knudsen, PH | 1 |
| Nielsen, PE | 1 |
| Nordén, B | 1 |
| Ygge, B | 1 |
| Guiotto, A | 4 |
| Rodighiero, P | 3 |
| Manzini, P | 1 |
| Pastorini, G | 2 |
| Bordin, F | 4 |
| Baccichetti, F | 4 |
| Carlassare, F | 3 |
| Vedaldi, D | 3 |
| Dall'Acqua, F | 2 |
| Tamaro, M | 4 |
| Recchia, G | 2 |
| Cristofolini, M | 2 |
| Gia, O | 1 |
| Anselmo, A | 1 |
| Conconi, MT | 2 |
| Antonello, C | 1 |
| Uriarte, E | 1 |
| Caffieri, S | 1 |
| Mostafa, WZ | 1 |
| Hussein, MF | 1 |
| Aly, EF | 1 |
| Khorshied, MM | 1 |
| Eweis, EB | 1 |
| Abdel Meged, AM | 1 |
| El-Hawary, MS | 1 |
| Hafez, VG | 1 |
| Shirsath, N | 1 |
| Wagner, K | 1 |
| Tangermann, S | 1 |
| Schlederer, M | 1 |
| Ringel, C | 1 |
| Kenner, L | 1 |
| Brüne, B | 1 |
| Wolf, P | 7 |
| Naasan, H | 1 |
| Dawe, RS | 3 |
| Ibbotson, SH | 4 |
| Richer, V | 1 |
| AlObaida, S | 1 |
| Kharazmi, P | 1 |
| Lee, TK | 1 |
| Kalia, S | 1 |
| Lui, H | 1 |
| Silva, FS | 1 |
| Oliveira, H | 1 |
| Moreiras, A | 1 |
| Fernandes, JC | 1 |
| Bronze-da-Rocha, E | 1 |
| Figueiredo, A | 1 |
| Custódio, JB | 1 |
| Rocha-Pereira, P | 1 |
| Santos-Silva, A | 1 |
| Al-Ismail, D | 1 |
| Edwards, C | 1 |
| Al-Ofi, O | 1 |
| Anstey, AV | 1 |
| Berneburg, M | 2 |
| Herzinger, T | 1 |
| Rampf, J | 1 |
| Hoetzenecker, W | 1 |
| Guenova, E | 1 |
| Meisner, C | 1 |
| Maetzke, J | 1 |
| Schaefer, T | 1 |
| Eberlein, B | 1 |
| Scharffetter-Kochanek, K | 1 |
| Rocken, M | 1 |
| Deeni, YY | 1 |
| Woods, JA | 1 |
| Wolf, CR | 2 |
| Smith, G | 2 |
| Chowdhari, S | 1 |
| Saini, N | 1 |
| Shoeibi, N | 1 |
| Taheri, A | 1 |
| Nikandish, M | 1 |
| Omidtabrizi, A | 1 |
| Khosravi, N | 1 |
| Kadkhoda, M | 1 |
| Moghaddam, SG | 1 |
| Kubo, R | 1 |
| Muramatsu, S | 1 |
| Sagawa, Y | 1 |
| Saito, C | 2 |
| Kasuya, S | 1 |
| Nishioka, A | 1 |
| Nishida, E | 1 |
| Yamazaki, S | 1 |
| Morita, A | 2 |
| Fang, JY | 1 |
| Fang, CL | 1 |
| Liu, CH | 1 |
| Su, YH | 1 |
| Maeda, A | 1 |
| Seckin, D | 1 |
| Usta, I | 1 |
| Yazici, Z | 1 |
| Senol, A | 1 |
| Singh, TP | 2 |
| Schön, MP | 2 |
| Wallbrecht, K | 2 |
| Michaelis, K | 1 |
| Rinner, B | 1 |
| Mayer, G | 1 |
| Schmidbauer, U | 1 |
| Strohmaier, H | 1 |
| Wang, XJ | 1 |
| Berroeta, L | 1 |
| Man, I | 1 |
| Ferguson, J | 3 |
| Konda, S | 1 |
| Maibach, HI | 1 |
| Inzinger, M | 1 |
| Heschl, B | 1 |
| Weger, W | 1 |
| Hofer, A | 3 |
| Legat, FJ | 2 |
| Gruber-Wackernagel, A | 1 |
| Tilz, H | 1 |
| Salmhofer, W | 1 |
| Quehenberger, F | 3 |
| Mantovani, L | 1 |
| Minghetti, S | 1 |
| Maranini, C | 1 |
| Furicchia, G | 1 |
| Borghi, A | 1 |
| Virgili, A | 1 |
| Dinkova-Kostova, AT | 1 |
| Weidlich, S | 1 |
| Farr, PM | 8 |
| Ehsani, AH | 1 |
| Ghaninejad, H | 1 |
| Kiani, A | 1 |
| Daneshpazhooh, M | 1 |
| Hosseini, SH | 1 |
| Noormohammadpoor, P | 1 |
| Archier, E | 3 |
| Devaux, S | 3 |
| Castela, E | 3 |
| Gallini, A | 3 |
| Aubin, F | 4 |
| Le Maître, M | 3 |
| Aractingi, S | 3 |
| Bachelez, H | 3 |
| Cribier, B | 3 |
| Joly, P | 3 |
| Jullien, D | 3 |
| Misery, L | 3 |
| Paul, C | 3 |
| Ortonne, JP | 5 |
| Richard, MA | 3 |
| Molochkov, VA | 1 |
| Kil'diushevskiĭ, AV | 1 |
| Molochkov, AV | 1 |
| Karzanov, OV | 1 |
| Iakubovskaia, ES | 1 |
| Fedulkina, VA | 1 |
| Leveque, N | 1 |
| Muret, P | 3 |
| Mary, S | 1 |
| Bérard, M | 1 |
| Makki, S | 4 |
| Pierre Kantelip, J | 1 |
| Humbert, P | 3 |
| Grundmann-Kollmann, M | 4 |
| Podda, M | 3 |
| Bräutigam, L | 1 |
| Hardt-Weinelt, K | 1 |
| Ludwig, RJ | 1 |
| Geisslinger, G | 1 |
| Kaufmann, R | 3 |
| Tegeder, I | 1 |
| Markham, T | 1 |
| Rogers, S | 8 |
| Collins, P | 4 |
| Park, JY | 1 |
| Rim, JH | 1 |
| Choe, YB | 1 |
| Youn, JI | 1 |
| Martin, S | 2 |
| Petitpain, N | 1 |
| Tréchot, P | 3 |
| Barbaud, A | 3 |
| Schmutz, JL | 3 |
| Pouaha, J | 1 |
| Ludwig, R | 1 |
| Zollner, TM | 1 |
| Ochsendorf, F | 1 |
| Thaci, D | 1 |
| Boehncke, WH | 1 |
| Krutmann, J | 2 |
| Kahofer, P | 1 |
| Kerl, H | 2 |
| Fink-Puches, R | 1 |
| Vongthongsri, R | 1 |
| Konschitzky, R | 1 |
| Seeber, A | 1 |
| Treitl, C | 1 |
| Hönigsmann, H | 23 |
| Tanew, A | 3 |
| Amornpinyokeit, N | 2 |
| Asawanonda, P | 2 |
| Steinmeyer, K | 1 |
| Nimnuan, C | 1 |
| Delrosso, G | 1 |
| Bornacina, C | 1 |
| Farinelli, P | 1 |
| Bellinzona, F | 1 |
| Leigheb, G | 1 |
| Colombo, E | 1 |
| Nyberg, F | 1 |
| Osika, I | 1 |
| Evengård, B | 1 |
| Henseler, T | 2 |
| Wolff, K | 17 |
| Christophers, E | 5 |
| Fenton, DA | 1 |
| Wilkinson, JD | 3 |
| LeVine, MJ | 2 |
| McGilvray, N | 1 |
| Baden, HP | 1 |
| Bertaux, B | 2 |
| Dubertret, L | 5 |
| Moreno, G | 2 |
| Meffert, H | 14 |
| Sönnichsen, N | 9 |
| Danno, K | 2 |
| Horio, T | 2 |
| Ozaki, M | 1 |
| Imamura, S | 1 |
| Roelandts, R | 4 |
| Zhang, GW | 1 |
| Diezel, W | 3 |
| Babaian, RS | 1 |
| Vladimirov, VV | 1 |
| Kulikova, EP | 1 |
| Panichkina, GS | 1 |
| Siddiqui, AH | 4 |
| Stolk, LM | 4 |
| Cormane, RH | 5 |
| Andersen, KE | 1 |
| Nozicková-Novotná, M | 1 |
| Prasad, BN | 1 |
| Pathak, MA | 4 |
| Marciani, MS | 1 |
| Rodighiero, G | 1 |
| Momtaz-T, K | 1 |
| Parrish, JA | 17 |
| Stern, RS | 11 |
| Momtaz, K | 1 |
| de Jongh, G | 1 |
| Bergers, M | 1 |
| Boezeman, JB | 1 |
| Verhagen, AR | 1 |
| Mier, PD | 1 |
| Lafond, G | 1 |
| Roy, PE | 1 |
| Grenier, R | 1 |
| Kleinerman, RA | 4 |
| Fitzpatrick, TB | 15 |
| Bleich, HL | 4 |
| De Bersagues, J | 1 |
| Beani, JC | 5 |
| Sarrazin, C | 1 |
| Amblard, P | 5 |
| Reymond, JL | 5 |
| Beriel, H | 4 |
| Boitard, M | 3 |
| Herfst, MJ | 5 |
| De Wolff, FA | 5 |
| Mashkilleysson, AL | 1 |
| Mashkilleysson, NA | 1 |
| Hofmann, C | 13 |
| Neiss, A | 1 |
| Plewig, G | 12 |
| Braun-Falco, O | 12 |
| Morhenn, VB | 1 |
| Benike, CJ | 1 |
| Engleman, EG | 1 |
| Mizuno, N | 6 |
| Gschnait, F | 15 |
| Stingl, G | 1 |
| Brenner, W | 6 |
| Jaschke, E | 6 |
| Konrad, K | 5 |
| Bond, CA | 1 |
| Grant, K | 1 |
| Boh, L | 1 |
| Andrew, E | 1 |
| Nilsen, A | 2 |
| Thune, P | 3 |
| Wiik, I | 1 |
| Neild, VS | 1 |
| Scott, LV | 1 |
| Goldstein, DP | 1 |
| Carter, DM | 4 |
| Ljunggren, B | 3 |
| Burkholder, J | 1 |
| Toda, K | 2 |
| Ishida, H | 1 |
| Nitsche, V | 2 |
| Rauschmeier, W | 1 |
| Schäfer-Korting, M | 2 |
| Korting, HC | 2 |
| Roser-Maass, E | 1 |
| Mutschler, E | 1 |
| Stolk, L | 1 |
| Korthals Altes-Levij van Vinninghe, HR | 1 |
| Kammeijer, A | 1 |
| Lauharanta, J | 1 |
| Juvakoski, T | 1 |
| Kanerva, L | 1 |
| Lassus, A | 1 |
| Bickers, DR | 1 |
| Ciafone, RA | 1 |
| Rhodes, AR | 1 |
| Audley, M | 1 |
| Freedberg, IM | 1 |
| Abelmann, WH | 1 |
| Thibodeau, LA | 4 |
| Lerman, S | 4 |
| Koch, HR | 2 |
| Glew, WB | 2 |
| McKeever, G | 1 |
| Roberts, WP | 1 |
| Malinin, G | 1 |
| Nigra, TP | 2 |
| Raff, M | 1 |
| Bardach, H | 1 |
| Westerhof, W | 3 |
| van Zwieten, PA | 1 |
| Shuster, S | 5 |
| Chadwick, L | 1 |
| Moss, C | 1 |
| Marks, J | 4 |
| Van Boven, M | 2 |
| Deheyn, T | 1 |
| Vander Stichele, G | 1 |
| Degreef, H | 2 |
| Daenens, P | 2 |
| Langner, A | 3 |
| Wolska, H | 2 |
| Monbaliu, JG | 1 |
| Bogaert, MG | 1 |
| De Bersaques, J | 1 |
| Hindryckx, P | 1 |
| Albert, J | 1 |
| Reid, T | 1 |
| Yancey, KB | 1 |
| Smith, JG | 2 |
| Worm, AM | 1 |
| Epstein, JH | 2 |
| Farber, EM | 3 |
| Bioulac, P | 1 |
| Denechaud, M | 1 |
| Dubuisson, L | 1 |
| Doutre, MS | 1 |
| Ducassou, D | 1 |
| Beylot, C | 1 |
| Megaw, J | 1 |
| Willis, I | 3 |
| Friedmann, PS | 1 |
| Fusco, RJ | 1 |
| Jordan, PA | 1 |
| Kelly, A | 1 |
| Samuel, M | 1 |
| Landthaler, M | 2 |
| Goldberg, LH | 2 |
| Cox, AJ | 4 |
| Abel, EA | 4 |
| Lavery, HA | 1 |
| Burrows, D | 1 |
| Marx, JL | 1 |
| Scher, RK | 1 |
| Metz, D | 9 |
| Barth, J | 2 |
| Bergmann, R | 1 |
| Dietz, O | 2 |
| Geidel, H | 2 |
| Heilmann, S | 3 |
| Kadner, H | 2 |
| Pinzer, B | 2 |
| Schade, C | 1 |
| Schiller, F | 2 |
| Edelbroek, PM | 1 |
| Pariser, DM | 1 |
| Wyles, RJ | 1 |
| Stevenson, IH | 1 |
| Kenicer, KJ | 1 |
| Johnson, BE | 4 |
| Frain-Bell, W | 4 |
| Washüttl, J | 3 |
| Greiter, F | 3 |
| Steiner, I | 3 |
| Morison, WL | 6 |
| De Rie, MA | 1 |
| Van Eendenburg, JP | 1 |
| Versnick, AC | 1 |
| Bos, JD | 1 |
| Gómez, MI | 1 |
| Azaña, JM | 1 |
| Arranz, I | 1 |
| Harto, A | 1 |
| Ledo, A | 1 |
| Berg, M | 1 |
| Ros, AM | 2 |
| Calzavara-Pinton, PG | 4 |
| Ortel, B | 6 |
| Zane, C | 3 |
| De Panfilis, G | 5 |
| Pai, S | 1 |
| Srinivas, CR | 1 |
| el-Mofty, AM | 1 |
| el-Sawalhy, H | 1 |
| el-Mofty, M | 1 |
| Hallman, CP | 1 |
| Koo, JY | 2 |
| Omohundro, C | 1 |
| Lee, J | 1 |
| Agache, P | 2 |
| Nivsarkar, M | 1 |
| Kumar, GP | 1 |
| Laloraya, M | 1 |
| Haciyakupoğlu, G | 1 |
| Varinli, I | 1 |
| Memişoğlu, HR | 1 |
| Varinli, S | 1 |
| Demircan, N | 1 |
| Denli, G | 1 |
| Bonnot, D | 3 |
| Calzavara-Pinton, P | 3 |
| Franceschini, F | 1 |
| Rastrelli, M | 1 |
| Manera, C | 1 |
| Cattaneo, R | 1 |
| Perl, S | 2 |
| Kinaciyan, T | 1 |
| Poskitt, BL | 1 |
| Wojnarowska, FT | 1 |
| Chia, YC | 1 |
| Kucová, D | 1 |
| Marysková, D | 1 |
| Davídková, P | 1 |
| Gasparic, J | 1 |
| Bechtel, P | 1 |
| Urien, S | 1 |
| Tillement, JP | 1 |
| Pham, CT | 1 |
| Sakuntabhai, A | 5 |
| Sharpe, GR | 1 |
| Carlino, AM | 1 |
| Diffey, BL | 9 |
| Streit, V | 1 |
| Wiedow, O | 1 |
| Bendriss, EK | 1 |
| Bechtel, Y | 1 |
| Bendriss, A | 1 |
| Humbert, PH | 1 |
| Paintaud, G | 1 |
| Magnette, J | 1 |
| Bechtel, PR | 1 |
| Bolognia, JL | 1 |
| Freije, L | 1 |
| Amici, L | 1 |
| Dellostritto, J | 1 |
| Gasparro, FP | 5 |
| Anigbogu, AN | 1 |
| Williams, AC | 1 |
| Barry, BW | 1 |
| Amici, LA | 1 |
| Gritiyarangsan, P | 1 |
| Sindhavananda, J | 1 |
| Rungrairatanaroj, P | 1 |
| Kullavanijaya, P | 1 |
| Rappersberger, K | 2 |
| Födinger, D | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dipeptidyl Peptidase-4 Inhibition and Narrow-band Ultraviolet-B Light in Psoriasis (DINUP): A Randomised Clinical Trial[NCT02347501] | Phase 2 | 118 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| Skin Disease and Pulmonary Mortality After Transplantation[NCT03320928] | 79 participants (Actual) | Observational | 2016-10-21 | Completed | |||
| Adaption of the Skin Sun Sensitivity Scale for People With All Pigment Varieties[NCT01975038] | 292 participants (Actual) | Observational | 2013-10-31 | Completed | |||
| A Single Arm Study of Extracorporeal Photoimmune Therapy With Uvadex For Corticosteroid Sparing in Patients With Corticosteroid-Dependent Crohn's Disease Who May Also Be Refractory or Intolerant to Immunosuppressants and/or Anti-Tumor Necrosis Factor Agen[NCT00056355] | Phase 1 | 10 participants | Interventional | 2003-03-31 | Completed | ||
| Randomized Controlled Trial of 308 nm Excimer Laser for Treatment of Nail Psoriasis[NCT02168933] | 8 participants (Actual) | Interventional | 2014-01-31 | Completed | |||
| the Association Between Serum Uric Acid Levels and the Risk of Metabolic Syndrome in Type 2 Diabetes Mellitus[NCT04575389] | 100 participants (Anticipated) | Observational | 2020-10-01 | Not yet recruiting | |||
| Photochemotherapy of Acute Graft-versus-host Disease (aGVHD) of the Skin - is Graft-versus-leukemia Preserved in Patients Transplanted for Acute Leukemia?[NCT02631993] | 47 participants (Actual) | Observational | 2014-10-31 | Completed | |||
| Evaluation of Spa Therapy in the Treatment of Plaque Psoriasis, a Randomized, Controlled, Open Multicenter Study[NCT02098213] | 128 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
This is an instrument that scores nail psoriasis severity. Severity for each nail is measured on a scale of 0-13, where crumbling, pitting, onycholysis and oil spots together are each graded 0-3, and other features (leukonychia, splinter hemorrhages, hyperkeratosis, and red spots in lunula) are scored 0 (absent) or 1 (present). Higher score indicates more severe nail psoriasis with 13 being the most severe and 0 being no nail disease present. (NCT02168933)
Timeframe: at 16 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Active | 6.3 |
| Sham | 6.0 |
this is a subjective patient reported scale, 0-100, where 100 is the most severe global assessment of the patient's nail psoriasis, and 0 is clear (no nail disease present). (NCT02168933)
Timeframe: at 16 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Active | 58.6 |
| Sham | 55.4 |
21 reviews available for methoxsalen and Palmoplantaris Pustulosis
| Article | Year |
|---|---|
Flu-like syndrome, bronchoconstriction and fever caused by 5-methoxypsoralen: the first case report and literature review.
Topics: 5-Methoxypsoralen; Bronchial Hyperreactivity; Bronchoconstriction; Fever; Humans; Male; Methoxsalen; | 2011 |
Efficacy of psoralen UV-A therapy vs. narrowband UV-B therapy in chronic plaque psoriasis: a systematic literature review.
Topics: Chronic Disease; Humans; Methoxsalen; Photochemotherapy; Photosensitizing Agents; Psoriasis; Randomi | 2012 |
Carcinogenic risks of psoralen UV-A therapy and narrowband UV-B therapy in chronic plaque psoriasis: a systematic literature review.
Topics: Chronic Disease; Female; Humans; Male; Methoxsalen; Photochemotherapy; Photosensitizing Agents; Psor | 2012 |
Ocular damage in patients with psoriasis treated by psoralen UV-A therapy or narrow band UVB therapy: a systematic literature review.
Topics: Eye; Eye Protective Devices; Humans; Methoxsalen; Photochemotherapy; Photosensitizing Agents; Psoria | 2012 |
Mutagenicity and carcinogenicity of methoxsalen plus UV-A.
Topics: Animals; Carcinogens; Guinea Pigs; Humans; Hypersensitivity, Delayed; Immunosuppression Therapy; In | 1984 |
[Psoriasis treatment by a photochemotherapy (PUVA) method].
Topics: Adolescent; Adult; Aged; Dermatitis, Exfoliative; Evaluation Studies as Topic; Female; Humans; Male; | 1980 |
Oral methoxsalen photochemotherapy of psoriasis and mycosis fungoides.
Topics: Adolescent; Adult; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cataract; Child; Furoco | 1980 |
Clinical aspects of photochemotherapy.
Topics: 5-Methoxypsoralen; Animals; Humans; Methoxsalen; Photochemotherapy; Psoriasis; PUVA Therapy; Risk | 1981 |
Photochemotherapy of psoriasis with methoxsalen and longwave ultraviolet light (PUVA).
Topics: Humans; Kinetics; Methoxsalen; Photochemotherapy; Psoriasis; PUVA Therapy | 1981 |
PUVA therapy is preferable to UVB phototherapy in the management of HIV-associated dermatoses.
Topics: HIV Infections; Humans; Methoxsalen; Phototherapy; Psoriasis; PUVA Therapy | 1996 |
Therapy with orally administered methoxsalen and ultraviolet A radiation during childhood increases the risk of basal cell carcinoma. The PUVA Follow-up Study.
Topics: Administration, Oral; Adolescent; Carcinoma, Basal Cell; Follow-Up Studies; Humans; Male; Methoxsale | 1996 |
5-Methoxypsoralen. A review of its effects in psoriasis and vitiligo.
Topics: 5-Methoxypsoralen; Humans; Methoxsalen; Psoriasis; Vitiligo | 1998 |
[Present-day status of the problem of psoriasis and the tasks of its development].
Topics: Cell Division; HLA Antigens; Humans; Methoxsalen; Neurotransmitter Agents; Papaverine; Psoriasis; Ul | 1979 |
Dermatology.
Topics: Acne Vulgaris; Anti-Bacterial Agents; Humans; Methoxsalen; Psoriasis; Rosacea; Skin Diseases; Skin D | 1976 |
[Oral photochemotherapy (author's transl)].
Topics: Adult; Dose-Response Relationship, Radiation; Eczema; Eye Protective Devices; Female; Humans; Hypers | 1977 |
Determination of 8-methoxypsoralen in serum, aqueous, and lens: relation to long-wave ultraviolet phototoxicity in experimental and clinical photochemotherapy.
Topics: Adolescent; Adult; Aged; Animals; Aqueous Humor; Biological Assay; Cataract; Female; Humans; Lens, C | 1979 |
Photochemotherapy in psoriasis: a review.
Topics: Animals; Cataract; Humans; Methoxsalen; Mutagens; Photochemotherapy; Psoriasis; Rats; Skin Diseases; | 1979 |
Editorial: Photochemotherapy in psoriasis.
Topics: Animals; Cataract; Coumarins; Ficusin; Furocoumarins; Humans; Methoxsalen; Mice; Nausea; Pruritus; P | 1976 |
An appraisal of current systemic chemotherapy for psoriasis.
Topics: Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azauridine; Cell Division | 1976 |
[Systemic photoallergy induced by methoxalen].
Topics: Adult; Erythema; Female; Humans; Male; Methoxsalen; Patch Tests; Photosensitivity Disorders; Psorias | 1992 |
[Problems posed by the therapeutic use of photosensitizers in dermatology].
Topics: 5-Methoxypsoralen; Coal Tar; DNA; Furocoumarins; Hematoporphyrin Derivative; Hematoporphyrin Photora | 1986 |
75 trials available for methoxsalen and Palmoplantaris Pustulosis
| Article | Year |
|---|---|
Minimal phototoxic dose (MPD) measurements for topical photochemotherapy using a semiautomated MPD tester.
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Photosensitizing Agents; Pr | 2013 |
Efficacy of bath psoralen plus ultraviolet A (PUVA) vs. system PUVA in psoriasis: a prospective, open, randomized, multicentre study.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Baths; Female; Humans; Male; Methoxsal | 2013 |
Effect of oral photochemotherapy (8-methoxypsoralen + UVA) on the electrophysiologic function of retina.
Topics: Adult; Eczema; Electroretinography; Humans; Methoxsalen; Photochemotherapy; Photosensitizing Agents; | 2016 |
Bath-PUVA therapy induces circulating regulatory T cells in patients with psoriasis.
Topics: Adult; Aged; Baths; Case-Control Studies; CD4 Antigens; Female; Forkhead Transcription Factors; Huma | 2009 |
Randomized double-blind comparative study of 8-methoxypsoralen bath plus UV-A treatment regimens.
Topics: Administration, Cutaneous; Adult; Baths; Biological Availability; Double-Blind Method; Drug Administ | 2010 |
Comparison of topical 8-methoxypsoralen and narrowband ultraviolet B with narrowband ultraviolet B alone in treatment-resistant sites in plaque-type psoriasis: a placebo-controlled study.
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Photosensitizing Agents; Psoriasis; Sev | 2011 |
Narrowband UV-B (TL-01) phototherapy vs oral 8-methoxypsoralen psoralen-UV-A for the treatment of chronic plaque psoriasis.
Topics: Administration, Oral; Adult; Chronic Disease; Female; Humans; Male; Methoxsalen; Middle Aged; Photos | 2003 |
Narrowband UVB and cream psoralen-UVA combination therapy for plaque-type psoriasis.
Topics: Administration, Topical; Adult; Aged; Combined Modality Therapy; Female; Humans; Male; Methoxsalen; | 2004 |
Reduction of treatment frequency and UVA dose does not substantially compromise the antipsoriatic effect of oral psoralen-UVA.
Topics: Administration, Oral; Adult; Drug Administration Schedule; Female; Humans; Male; Methoxsalen; Prospe | 2004 |
Paired comparison of bathwater versus oral delivery of 8-methoxypsoralen in psoralen plus ultraviolet: A therapy for chronic palmoplantar psoriasis.
Topics: Adult; Aged; Baths; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; Middle Aged | 2006 |
Randomized, double-blind comparison of 1 mg/L versus 5 mg/L methoxsalen bath-PUVA therapy for chronic plaque-type psoriasis.
Topics: Adult; Chronic Disease; Double-Blind Method; Female; Humans; Male; Methoxsalen; Middle Aged; Psorias | 2006 |
8-Methoxypsoralen cream plus targeted narrowband ultraviolet B for psoriasis.
Topics: Administration, Cutaneous; Adolescent; Adult; Combined Modality Therapy; Dermatologic Agents; Female | 2006 |
Topical 8-methoxypsoralen enhances the therapeutic results of targeted narrowband ultraviolet B phototherapy for plaque-type psoriasis.
Topics: Administration, Topical; Adolescent; Adult; Combined Modality Therapy; Dose-Response Relationship, D | 2008 |
Bath PUVA and psoriasis: is a milder treatment a worse treatment?
Topics: Adult; Baths; Clinical Protocols; Dermatitis, Phototoxic; Female; Humans; Male; Methoxsalen; Middle | 2008 |
Oral 8-methoxypsoralen photochemotherapy of psoriasis. The European PUVA study: a cooperative study among 18 European centres.
Topics: Administration, Oral; Adult; Clinical Trials as Topic; Europe; Female; Follow-Up Studies; Humans; In | 1981 |
Topical 8-methoxypsoralen photochemotherapy of psoriasis: a clinical study.
Topics: Administration, Topical; Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Methoxsalen; M | 1983 |
Combination of psoralens and ultraviolet A and ultraviolet B in the treatment of psoriasis vulgaris: a bilateral comparison study.
Topics: Adolescent; Adult; Aged; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administr | 1984 |
[Double-blind studies on the effect of topical PUVA therapy for psoriasis. Supplement: open controlled studies on the effect of topical PUVA and topical steroid therapy for psoriasis. (author's transl)].
Topics: Administration, Topical; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; | 1980 |
Photochemotherapy in psoriasis-clinical response and 8-MOP plasma concentrations at two dose levels.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Methoxsalen; Middle Aged; P | 1981 |
Difference in bioavailability between two brands of 8-methoxypsoralen and its impact on the clinical response in psoriatic patients.
Topics: Biological Availability; Humans; Methoxsalen; Psoriasis; PUVA Therapy | 1982 |
Serum levels of 8-methoxypsoralen in two different drug preparations: correlation with photosensitivity and UV-A dose requirements for photochemotherapy.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Humans; Kinetics; Methoxsalen; Middle Aged; Photo | 1982 |
Problems with commercial formulations of 8-methoxypsoralen.
Topics: Absorption; Biological Availability; Dosage Forms; Humans; Kinetics; Methoxsalen; Psoriasis; Time Fa | 1981 |
Combination of methoxsalen and ultraviolet B (UVB) versus UVB radiation alone in treatment of psoriasis: a bilateral comparison study.
Topics: Adult; Humans; Methoxsalen; Psoriasis; PUVA Therapy; Ultraviolet Therapy | 1995 |
A new psoralen-containing gel for topical PUVA therapy: development, and treatment results in patients with palmoplantar and plaque-type psoriasis, and hyperkeratotic eczema.
Topics: Eczema; Ficusin; Gels; Humans; Male; Methoxsalen; Psoriasis; PUVA Therapy; Trioxsalen | 1995 |
Treatment of psoriasis with psoralens and ultraviolet A. A double-blind comparison of 8-methoxypsoralen and 5-methoxypsoralen.
Topics: 5-Methoxypsoralen; Absorption; Adult; Aged; Chemical and Drug Induced Liver Injury; Double-Blind Met | 1994 |
Safety and effectiveness of an aggressive and individualized bath-PUVA regimen in the treatment of psoriasis.
Topics: Administration, Oral; Adult; Aged; Baths; Female; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; | 1994 |
Bathing suit delivery of 8-methoxypsoralen for psoriasis: a double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Drug Delivery Systems; Female; Humans; Male; Methoxsal | 1994 |
Clinical study of a new preparation of 8-methoxypsoralen in photochemotherapy.
Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Capsules; Child; Dose-Response Rel | 1994 |
Treatment of psoriasis with a new micronized 5-methoxypsoralen tablet and UVA radiation.
Topics: 5-Methoxypsoralen; Administration, Oral; Adult; Drug Tolerance; Female; Humans; Male; Methoxsalen; M | 1994 |
Comparison of narrow-band (311 nm) UVB and broad-band UVA after oral or bath-water 8-methoxypsoralen in the treatment of psoriasis.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Baths; Combined Modality Therapy; Huma | 1993 |
Response of psoriasis to psoralen-UVB photochemotherapy.
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Psoriasis; Skin; Tim | 1993 |
Calculation of 8-methoxypsoralen dose according to body surface area in PUVA treatment.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Body Height; Body Surface Area; Body Weight; Drug Admini | 1995 |
Comparison of psoralen-UVB and psoralen-UVA photochemotherapy in the treatment of psoriasis.
Topics: Adult; Humans; Methoxsalen; Photosensitizing Agents; Psoriasis; PUVA Therapy | 1997 |
Narrow band UVB (311 nm) phototherapy and PUVA photochemotherapy: a combination.
Topics: Administration, Cutaneous; Adult; Aged; Dermatitis, Phototoxic; Erythema; Humans; Male; Methoxsalen; | 1998 |
PUVA-bath photochemotherapy (PUVA-soak therapy) of recalcitrant dermatoses of the palms and soles.
Topics: Administration, Cutaneous; Adult; Combined Modality Therapy; Female; Foot Dermatoses; Hand Dermatose | 1999 |
Treatment of severe recalcitrant dermatoses of the palms and soles with PUVA-bath versus PUVA-cream therapy.
Topics: Administration, Cutaneous; Adult; Aged; Eczema; Emulsions; Female; Foot Dermatoses; Hand Dermatoses; | 1999 |
A comparison of bathwater and oral delivery of 8-methoxypsoralen in PUVA therapy for plaque psoriasis.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Baths; Female; Humans; Male; Methoxsal | 2000 |
Plasma and skin concentration of 5-methoxypsoralen in psoriatic patients after oral administration.
Topics: 5-Methoxypsoralen; Administration, Oral; Adult; Dermis; Epidermis; Female; Humans; Male; Methoxsalen | 2001 |
A comparison of the effect of narrow-band ultraviolet B in the treatment of psoriasis after salt-water baths and after 8-methoxypsoralen baths.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Baths; Female; Humans; Male; Methoxsalen; Middle Aged; P | 2001 |
Treatment of psoriasis with trioxsalen baths and dysprosium lamps.
Topics: Adolescent; Adult; Aged; Baths; Coumarins; Female; Humans; Male; Methoxsalen; Middle Aged; Photochem | 1976 |
Comparison of photochemotherapy and dithranol in the treatment of chronic plaque psoriasis.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Anthracenes; Anthralin; Chronic Di | 1979 |
Phototesting and dosimetry for photochemotherapy.
Topics: Body Weight; Clinical Trials as Topic; Erythema; Humans; Methoxsalen; Psoriasis; Skin Pigmentation; | 1977 |
Photochemotherapy of psoriasis using methoxsalen and sunlight. A controlled study.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Methoxsalen; Photochemotherapy; Placebos; Pso | 1977 |
Psoriasis treated with clobetasol propionate and photochemotherapy.
Topics: Adult; Betamethasone; Clinical Trials as Topic; Clobetasol; Drug Therapy, Combination; Female; Human | 1978 |
[Photochemotherapy by 8-methoxypsoralen and UVA in psoriasis vulgaris--clinical experiences in 5 dermatological departments of GDR (author's transl)].
Topics: Clinical Trials as Topic; Female; Humans; Male; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviol | 1978 |
[Photochemotherapy of psoriasis: increasing its effectiveness with an oral aromatic retinoid (clinical results in 134 patients) (author's transl)].
Topics: Administration, Oral; Clinical Trials as Topic; Follow-Up Studies; Humans; Methoxsalen; Psoriasis; R | 1978 |
Treatment of psoriasis with 8-methoxypsoralen and sunlight.
Topics: Administration, Topical; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Evaluation | 1978 |
A randomized, controlled clinical trial comparing photochemotherapy with dithranol in the initial treatment of chronic plaque psoriasis.
Topics: Adolescent; Adult; Aged; Anthracenes; Anthralin; Clinical Trials as Topic; Female; Humans; Male; Met | 1978 |
[1st attempt at photochemotherapy of psoriasis in the USSR].
Topics: Adolescent; Adult; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Methoxsalen; Mid | 1979 |
Photochemotherapy for psoriasis. A clinical cooperative study of PUVA-48 and PUVA-64.
Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Child; Clinical Trials as Topic; Eye Diseases; | 1979 |
6-Thioguanine resistant peripheral blood lymphocytes in humans following psoralen, long-wave ultraviolet light (PUVA) therapy.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Lymphocytes; Male; Methoxsalen; Middle Aged; Mutati | 1979 |
Antinuclear antibodies and oral methoxsalen photochemotherapy (PUVA) for psoriasis.
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Child; Child, Preschool; Clinical Trials as Topic; | 1979 |
[Photochemotherapy, a new method for the treatment of psoriasis].
Topics: Clinical Trials as Topic; Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1979 |
Topical methoxsalen photochemotherapy in the treatment of palmoplantar pustulosis and psoriasis.
Topics: Administration, Topical; Adult; Aged; Clinical Trials as Topic; Female; Foot Dermatoses; Hand Dermat | 1979 |
Combination therapy for psoriasis. Psoralens plus long-wave ultraviolet radiation with betamethasone valerate.
Topics: Adult; Betamethasone; Betamethasone Valerate; Evaluation Studies as Topic; Female; Humans; Male; Met | 1979 |
Controlled study of PUVA and adjunctive topical therapy in the management of psoriasis.
Topics: Adult; Anthralin; Coal Tar; Drug Therapy, Combination; Fluocinolone Acetonide; Humans; Methoxsalen; | 1978 |
[Psoriasis vulgaris. Treatment with carbon-arc light baths and 8-methoxypsoralen. A double-blind investigation].
Topics: Adolescent; Adult; Aged; Carbon; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Huma | 1976 |
Photochemotherapy of psoriasis.
Topics: Clinical Trials as Topic; Ficusin; Humans; Long-Term Care; Methoxsalen; Psoriasis; Ultraviolet Thera | 1975 |
[Photochemotherapy of psoriasis].
Topics: Clinical Trials as Topic; Humans; Long-Term Care; Methoxsalen; Psoriasis; Ultraviolet Therapy | 1976 |
A reappraisal of the use of 5-methoxypsoralen in the therapy of psoriasis.
Topics: 5-Methoxypsoralen; Adult; Dose-Response Relationship, Radiation; Female; Humans; Male; Methoxsalen; | 1992 |
Liquid formulations of 8-methoxypsoralen (8-MOP) and 5-MOP: a prospective double-blind crossover assessment of acute non-phototoxic adverse effects.
Topics: 5-Methoxypsoralen; Adult; Aged; Dosage Forms; Double-Blind Method; Female; Humans; Male; Methoxsalen | 1992 |
Bath-water compared with oral delivery of 8-methoxypsoralen PUVA therapy for chronic plaque psoriasis.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Baths; Chronic Disease; Female; Hu | 1992 |
Photochemotherapy for severe psoriasis without or in combination with acitretin: a randomized, double-blind comparison study.
Topics: Acitretin; Adolescent; Adult; Aged; Aspartate Aminotransferases; Cholesterol; Double-Blind Method; D | 1991 |
Plasma levels of 8-methoxypsoralen following oral or bath-water treatment.
Topics: Administration, Oral; Administration, Topical; Adult; Humans; Male; Methoxsalen; Middle Aged; Psoria | 1991 |
Outcomes of pregnancies among women and partners of men with a history of exposure to methoxsalen photochemotherapy (PUVA) for the treatment of psoriasis.
Topics: Abortion, Induced; Adult; Cohort Studies; Drug Evaluation; Female; Fetal Death; Follow-Up Studies; H | 1991 |
A double-blind, placebo-controlled trial of topical PUVA in persistent palmoplantar pustulosis.
Topics: Administration, Topical; Chronic Disease; Double-Blind Method; Foot; Hand; Humans; Methoxsalen; Psor | 1991 |
Serum 8-methoxypsoralen (8-MOP) concentrations after bath water delivery of 8-MOP plus UVA.
Topics: Adolescent; Adult; Aged; Chromatography, Liquid; Female; Humans; Male; Methoxsalen; Middle Aged; Pso | 1990 |
Antipsoriatic, erythematogenic, and Langerhans cell marker depleting effect of bath-psoralens plus ultraviolet A treatment. Comparison of 8-methoxypsoralen and trimethylpsoralen photosensitization.
Topics: Adenosine Triphosphatases; Adolescent; Adult; Dose-Response Relationship, Drug; Erythema; Female; HL | 1988 |
5-Methoxypsoralen (Bergapten) for photochemotherapy. Bioavailability, phototoxicity, and clinical efficacy in psoriasis of a new drug preparation.
Topics: 5-Methoxypsoralen; Biological Availability; Clinical Trials as Topic; Drug Administration Schedule; | 1988 |
Comparative efficacy of two dosage forms of oral methoxsalen in psoralens plus ultraviolet A therapy of psoriasis.
Topics: Administration, Oral; Capsules; Clinical Trials as Topic; Double-Blind Method; Humans; Methoxsalen; | 1987 |
5-Methoxy psoralen, etretinate, and UVA for psoriasis.
Topics: 5-Methoxypsoralen; Administration, Topical; Drug Administration Schedule; Drug Therapy, Combination; | 1987 |
PUVA therapy for psoriasis: comparison of oral and bath-water delivery of 8-methoxypsoralen.
Topics: Administration, Oral; Adult; Baths; Female; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; PUVA | 1986 |
Bioavailability study of two different 8-methoxypsoralen (8-MOP) preparations in patients receiving PUVA therapy.
Topics: Biological Availability; Capsules; Clinical Trials as Topic; Crystallization; Humans; Methoxsalen; P | 1985 |
Standardizing 8-methoxypsoralen plasma profiles by using an emulsion form.
Topics: Emulsions; Humans; Methoxsalen; Psoriasis; PUVA Therapy; Time Factors | 1985 |
Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light.
Topics: Administration, Oral; Adult; Cell Division; Depression, Chemical; DNA; Humans; Methoxsalen; Psoriasi | 1974 |
Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light.
Topics: Administration, Oral; Adult; Cell Division; Depression, Chemical; DNA; Humans; Methoxsalen; Psoriasi | 1974 |
Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light.
Topics: Administration, Oral; Adult; Cell Division; Depression, Chemical; DNA; Humans; Methoxsalen; Psoriasi | 1974 |
Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light.
Topics: Administration, Oral; Adult; Cell Division; Depression, Chemical; DNA; Humans; Methoxsalen; Psoriasi | 1974 |
376 other studies available for methoxsalen and Palmoplantaris Pustulosis
| Article | Year |
|---|---|
Psoralenamines. 3. Synthesis, pharmacological behavior, and DNA binding of 5-(aminomethyl)-8-methoxy-, 5-[[(3-aminopropyl)oxy]methyl]-, and 8-[(3-aminopropyl)oxy]psoralen derivatives.
Topics: Animals; Cell Division; Cell Line; Cross-Linking Reagents; DNA; Female; Furocoumarins; Hemolysis; Hu | 1985 |
6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; DNA; DNA Replication; Furocoumarins; Humans; Mutag | 1984 |
4'-Methylangelicins: new potential agents for the photochemotherapy of psoriasis.
Topics: Animals; Cell Division; DNA; Epidermis; Furocoumarins; Humans; Mice; Mutagenicity Tests; Phototherap | 1983 |
4'-Methyl derivatives of 5-MOP and 5-MOA: synthesis, photoreactivity, and photobiological activity.
Topics: 5-Methoxypsoralen; Animals; DNA; DNA, Bacterial; Furocoumarins; Guinea Pigs; Methoxsalen; Oxygen; Po | 1996 |
Circulating T regulatory cells in patients with psoriasis with and without atherosclerosis: A pilot comparative study before and after photochemotherapy.
Topics: Atherosclerosis; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 2021 |
8-Methoxypsoralen Plus Ultraviolet A Reduces the Psoriatic Response to Imiquimod in a Murine Model.
Topics: Aminoquinolines; Animals; Cytokines; Disease Models, Animal; Female; Gene Expression Regulation; Imi | 2018 |
Efficacy of localized hand and foot phototherapy: a review of patients treated in a teaching hospital setting.
Topics: 5-Methoxypsoralen; Foot Dermatoses; Hand Dermatoses; Hospitals, Teaching; Humans; Methoxsalen; Photo | 2019 |
Old is gold? Retrospective evaluation of efficacy and safety of topical psoralen-ultraviolet A phototherapy for palmoplantar psoriasis and dermatitis.
Topics: Dermatitis; Humans; Methoxsalen; Psoriasis; PUVA Therapy; Retrospective Studies; Severity of Illness | 2019 |
Cytotoxic and genotoxic effects of acitretin, alone or in combination with psoralen-ultraviolet A or narrow-band ultraviolet B-therapy in psoriatic patients.
Topics: Acitretin; Apoptosis; Cell Division; Combined Modality Therapy; Comet Assay; Dose-Response Relations | 2013 |
Bath vs. oral psoralen plus ultraviolet A: is one more effective than the other?
Topics: Baths; Female; Humans; Male; Methoxsalen; Photosensitizing Agents; Psoriasis; PUVA Therapy | 2013 |
Cytochrome P450 CYP1B1 interacts with 8-methoxypsoralen (8-MOP) and influences psoralen-ultraviolet A (PUVA) sensitivity.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; CHO Cells; Cricetulus; Cytochrome P-450 CYP1B1; Cytochrome P | 2013 |
hsa-miR-4516 mediated downregulation of STAT3/CDK6/UBE2N plays a role in PUVA induced apoptosis in keratinocytes.
Topics: 3' Untranslated Regions; Apoptosis; Base Sequence; Cell Survival; Cyclin-Dependent Kinase 6; Down-Re | 2014 |
Bath-PUVA therapy improves impaired resting regulatory T cells and increases activated regulatory T cells in psoriasis.
Topics: Adult; Aged; Aged, 80 and over; Baths; Female; Forkhead Transcription Factors; Humans; Male; Methoxs | 2017 |
Lipid nanoparticles as vehicles for topical psoralen delivery: solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC).
Topics: Animals; Calorimetry, Differential Scanning; Drug Carriers; Female; Ficusin; Lipids; Methoxsalen; Mi | 2008 |
Topical 8-methoxypsoralen increases the efficacy of narrowband ultraviolet B in psoriasis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Methoxsal | 2009 |
8-methoxypsoralen plus ultraviolet A therapy acts via inhibition of the IL-23/Th17 axis and induction of Foxp3+ regulatory T cells involving CTLA4 signaling in a psoriasis-like skin disorder.
Topics: Animals; Antigens, CD; Cell Separation; CTLA-4 Antigen; Disease Models, Animal; Enzyme-Linked Immuno | 2010 |
Percutaneous penetration of 5-methoxypsoralen in rhesus monkeys.
Topics: 5-Methoxypsoralen; Administration, Cutaneous; Animals; Carbon Isotopes; Injections, Intramuscular; M | 2011 |
Efficacy of psoralen plus ultraviolet A therapy vs. biologics in moderate to severe chronic plaque psoriasis: retrospective data analysis of a patient registry.
Topics: 5-Methoxypsoralen; Adult; Aged; Antibodies, Monoclonal; Biological Products; Chronic Disease; Combin | 2011 |
Glutathione S-transferase genotype is associated with sensitivity to psoralen-ultraviolet A photochemotherapy.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Erythema; Female; Gene Expression; Genoty | 2012 |
8-Methoxypsoralen plus UVA treatment increases the proportion of CLA+ CD25+ CD4+ T cells in lymph nodes of K5.hTGFβ1 transgenic mice.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Disease Models, Animal; Interleukin-2 Receptor alp | 2012 |
[Clinical and immunological aspects of extracorporeal photochemotherapy for psoriasis and psoriatic arthritis].
Topics: Adult; Aged; Arthritis, Psoriatic; Combined Modality Therapy; Female; Histamine H1 Antagonists; Huma | 2012 |
Validation of a microdialysis-gas chromatographic-mass spectrometric method to assess 8-methoxypsoralen in psoriatic patient dermis.
Topics: Adult; Aged; Calibration; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Methoxsalen; M | 2002 |
Spatial distribution of 8-methoxypsoralen penetration into human skin after systemic or topical administration.
Topics: Administration, Cutaneous; Administration, Oral; Administration, Topical; Adult; Aged; Female; Human | 2002 |
Anaphylaxis to 8-methoxypsoralen during photochemotherapy.
Topics: Administration, Oral; Anaphylaxis; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; PUVA Therapy | 2003 |
8-Methoxypsoralen-induced dysosmia.
Topics: Adult; Humans; Male; Methoxsalen; Olfaction Disorders; Psoriasis; PUVA Therapy; Smell | 2003 |
Methoxypsoralen-induced sleep disorder.
Topics: Adult; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Hu | 2003 |
[Methoxypsoralene plus UVA and unexpected side effects].
Topics: Female; Humans; Methoxsalen; Phototherapy; Psoriasis; Sleep Wake Disorders; Ultraviolet Rays | 2005 |
[Treatment of plaque-type psoriasis with cream-PUVA therapy].
Topics: Administration, Topical; Adult; Dermatologic Agents; Humans; Male; Methoxsalen; Middle Aged; Photose | 2001 |
"The Laundry Bag Project"--unequal distribution of dermatological healthcare resources for male and female psoriatic patients in Sweden.
Topics: Adult; Age Distribution; Balneology; Drug Prescriptions; Eczema; Emollients; Female; Healthcare Disp | 2008 |
Dose-related visual-field defects in patients receiving PUVA therapy.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Humans; Male; Methoxsalen; Photochemotherapy; | 1983 |
Effect of therapy on keratin polypeptide profiles of psoriatic epidermis.
Topics: Electrophoresis, Polyacrylamide Gel; Epidermis; Furocoumarins; Humans; Keratins; Methoxsalen; Peptid | 1980 |
Autoradiographic localization of 8-methoxypsoralen in psoriasis skin in vitro.
Topics: Autoradiography; Humans; Methoxsalen; Psoriasis; PUVA Therapy; Skin | 1981 |
Photobinding of 8-methoxypsoralen at psoriasis skin.
Topics: Humans; Light; Methoxsalen; Psoriasis; Skin | 1982 |
[Treatment of psoriasis by photochemotherapy: a comparison between the photosensitizing capsule of Angelica dahurica and 8-MOP].
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; P | 1983 |
[Inactivation and protection of phosphofructokinase during 8-methoxypsoralen and UVA-treatment].
Topics: Furocoumarins; Humans; Methoxsalen; Phosphofructokinase-1; Photochemotherapy; Psoriasis | 1980 |
Comparison of serum levels and clinical results of PUVA therapy with three different dosage forms of 8-methoxypsoralen.
Topics: Adolescent; Adult; Aged; Capsules; Enema; Humans; Kinetics; Methoxsalen; Middle Aged; Photochemother | 1984 |
Safety and therapeutic effectiveness of selected psoralens in psoriasis.
Topics: 5-Methoxypsoralen; DNA; Furocoumarins; Humans; Methoxsalen; Photochemotherapy; Photosensitivity Diso | 1984 |
Phototoxicity and antipsoriatic effect of a topical methoxypsoralen solution in relation to the application time.
Topics: Administration, Topical; Adult; Erythema; Female; Humans; Male; Methoxsalen; Photochemotherapy; Phot | 1984 |
Oral 8-methoxypsoralen photochemotherapy in psoriasis.
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Psoriasis; PUVA Ther | 1983 |
Comparative study of Puvasol and Puvasol plus topical application in treatment of psoriasis.
Topics: Adolescent; Adult; Child; Dermatologic Agents; Humans; Methoxsalen; Middle Aged; Ointments; Psoriasi | 1983 |
A study of the relationship between photosensitizing and therapeutic activity of 4,5',8-trimethylpsoralen, and its major metabolite 4,8-dimethyl, 5'-carboxypsoralen.
Topics: Animals; DNA; Female; Furocoumarins; Guinea Pigs; Humans; Male; Methoxsalen; Mice; Photochemistry; P | 1983 |
Skin typing for assessment of skin cancer risk and acute response to UV-B and oral methoxsalen photochemotherapy.
Topics: Administration, Oral; Humans; Methoxsalen; Photochemotherapy; Psoriasis; PUVA Therapy; Risk; Skin; S | 1984 |
The lethal effect of longwave ultraviolet light and PUVA. An analysis based upon human mesenchymal cells in vitro.
Topics: Cell Survival; Cells, Cultured; Humans; Methoxsalen; Monocytes; Psoriasis; Reference Values; Ultravi | 1984 |
Lens opacities appearing during therapy with methoxsalen and long-wavelength ultraviolet radiation.
Topics: Adult; Aged; Cataract; Eye Protective Devices; Female; Humans; Male; Methoxsalen; Middle Aged; Photo | 1984 |
Phototoxic reactions to photoactive drugs in patients treated with PUVA.
Topics: Adult; Chlorothiazide; Demeclocycline; Furosemide; Humans; Methoxsalen; Middle Aged; Nalidixic Acid; | 1980 |
Minimal phototoxic doses of 8-MOP plasma levels in PUVA patients.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; PUVA Therapy | 1983 |
Comparison between plasma levels of 8-methoxypsoralen and skin photosensitivity: the interest of pharmacokinetic studies during photochemotherapy of psoriasis.
Topics: Adolescent; Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Kinetics; Male; Metho | 1983 |
Intraindividual and interindividual variability in 8-methoxypsoralen kinetics and effect in psoriatic patients.
Topics: Dose-Response Relationship, Radiation; Humans; Kinetics; Longitudinal Studies; Methoxsalen; Psoriasi | 1983 |
[Comparison of RePUVA and aromatic retinoid Ro 10-9359 with methotrexate in severe forms of psoriasis].
Topics: Drug Resistance; Drug Therapy, Combination; Etretinate; Humans; Methotrexate; Methoxsalen; Photochem | 1983 |
[Oral 8-methoxypsoralen-UVA (PUVA) therapy in psoriasis: comparison of 3 treatment protocols].
Topics: Female; Furocoumarins; Humans; Male; Methoxsalen; Photochemotherapy; Psoriasis; Time Factors | 1980 |
Inhibition of cell mediated immune responses by 8-methoxypsoralen and long-wave ultraviolet light: a possible explanation for the clinical effects of photoactivated psoralen.
Topics: Epidermis; Humans; Immunity, Cellular; Methoxsalen; Monocytes; Psoriasis; T-Lymphocytes; Ultraviolet | 1980 |
Long-term photochemotherapy: histopathological and immunofluorescence observations in 243 patients.
Topics: Adult; Antibodies, Antinuclear; Fluorescent Antibody Technique; Humans; Methoxsalen; Middle Aged; Ph | 1980 |
Plasma levels of 8-methoxypsoralen in psoriatic patients receiving topical 8-methoxypsoralen.
Topics: Administration, Topical; Chromatography, High Pressure Liquid; Female; Humans; Male; Methoxsalen; Ph | 1982 |
Minimal phototoxic doses and 8-MOP plasma levels in PUVA patients.
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Periodicity; Photochemotherapy; Psorias | 1982 |
Topical methoxsalen followed immediately by long-wave UV irradiation. A preliminary report on the treatment of psoriasis.
Topics: Administration, Topical; Adult; Animals; DNA; Guinea Pigs; Humans; Male; Methoxsalen; Middle Aged; M | 1982 |
Influenced of food on the kinetics of 8-methoxypsoralen in serum and suction blister fluid in psoriatic patients.
Topics: Blister; Food; Humans; Kinetics; Methoxsalen; Psoriasis; PUVA Therapy | 1982 |
Intraindividual variations of 8-methoxypsoralen plasma levels.
Topics: Adult; Aged; Biological Availability; Female; Humans; Intestinal Absorption; Liver; Male; Metabolic | 1982 |
Determination of 8-methoxypsoralen levels in plasma and skin suction blister fluid by a new sensitive fluorodensitometric method.
Topics: Adult; Aged; Blister; Densitometry; Exudates and Transudates; Female; Fluorometry; Humans; Male; Met | 1982 |
Microenema of 8-methoxypsoralen in photochemotherapy of psoriasis.
Topics: Adult; Aged; Enema; Female; Humans; Kinetics; Male; Methoxsalen; Middle Aged; Photochemotherapy; Pso | 1982 |
Pharmacokinetics of 8-methoxypsoralen in serum and suction blister fluid.
Topics: Blister; Kinetics; Methoxsalen; Photochemotherapy; Psoriasis; PUVA Therapy | 1982 |
Photochemotherapy of psoriasis: risk:benefit ratios.
Topics: Coal Tar; Humans; Methoxsalen; Photochemotherapy; Psoriasis; PUVA Therapy; Risk | 1981 |
The cardiovascular stress of photochemotherapy (PUVA).
Topics: Adult; Air Conditioning; Blood Pressure; Body Temperature; Cardiovascular System; Female; Heart Rate | 1980 |
Effect of methoxsalen photochemotherapy on cost of treatment for psoriasis. An example of technological assessment.
Topics: Ambulatory Care; Costs and Cost Analysis; Female; Hospitalization; Humans; Length of Stay; Male; Met | 1981 |
[PUVA treatment and the problem of ocular damage (author's transl)].
Topics: Eye Protective Devices; Humans; Lens Diseases; Lens, Crystalline; Methoxsalen; Photochemotherapy; Ps | 1981 |
Photochemotherapy and the eye: photoprotective factors.
Topics: Eye Protective Devices; Humans; Lens, Crystalline; Methoxsalen; Photochemotherapy; Psoriasis; PUVA T | 1980 |
[8-Methoxypsoralen (8-MOP)-a new galenic form and its relation to 8-MOP serum levels (author's transl)].
Topics: Dosage Forms; Humans; Methoxsalen; Photochemotherapy; Psoriasis; PUVA Therapy; Therapeutic Equivalen | 1981 |
Serum and urine concentrations of 5-methoxypsoralen after oral administration.
Topics: 5-Methoxypsoralen; Administration, Oral; Adult; Aged; Female; Humans; Kinetics; Male; Methoxsalen; M | 1981 |
Serum 25-OH vitamin D after photochemotherapy.
Topics: Adult; Aged; Calcifediol; Female; Humans; Hydroxycholecalciferols; Male; Methoxsalen; Middle Aged; P | 1981 |
Dietary influences on 8-MOP plasma levels in PUVA patients with psoriasis.
Topics: Diet; Humans; Methoxsalen; Photochemotherapy; Psoriasis; PUVA Therapy | 1981 |
New galenical form of 8-methoxypsoralen in photochemotherapy of psoriasis.
Topics: Adult; Female; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; PUVA Therapy | 1981 |
Plasma levels of 8-methoxypsoralen determined by high-pressure liquid chromatography in psoriatic patients ingesting drug from two manufacturers.
Topics: Adolescent; Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Male; Methoxsalen; Mi | 1980 |
Status of PUVA therapy.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1980 |
Microvascular leakage of plasma proteins after short-term PUVA treatment.
Topics: Adolescent; Adult; Aged; Capillary Permeability; Female; Humans; Male; Methoxsalen; Middle Aged; Pho | 1980 |
Psoralen photochemotherapy.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1980 |
Psoralen and ultraviolet A (PUVA)--a critique.
Topics: Carcinoma, Basal Cell; Cataract; Humans; Keratosis; Methoxsalen; Photochemotherapy; Psoriasis; Risk; | 1980 |
Unscheduled DNA synthesis in psoriatic skin after ultraviolet irradiation and the effects of a combined treatment with 8-methoxypsoralen and longwave ultraviolet radiation: a clinical study.
Topics: Adolescent; Adult; Aged; Autoradiography; Child; DNA; Female; Humans; Male; Methoxsalen; Middle Aged | 1980 |
Potential ocular complications from PUVA therapy and their prevention.
Topics: Adult; Animals; Eye Injuries; Eyeglasses; Humans; Lens, Crystalline; Methoxsalen; Photochemotherapy; | 1980 |
Photochemotherapy of psoriasis: DNA damage in blood lymphocytes.
Topics: DNA; Humans; Lymphocytes; Methoxsalen; Photochemotherapy; Psoriasis | 1980 |
PUVA therapy for psoriasis.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1980 |
In vivo autoradiography and planimetry of epidermis in psoriatics under PUVA-therapy.
Topics: Adult; Autoradiography; Epidermis; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Psoria | 1980 |
The mitotic index in psoriatic plaques and their response to PUVA therapy.
Topics: Humans; Methoxsalen; Mitosis; Mitotic Index; Photochemotherapy; Psoriasis; Skin | 1980 |
PUVAtherapy for psoriasis and other skin diseases an initial report.
Topics: Humans; Methoxsalen; Psoriasis; Ultraviolet Therapy | 1980 |
Ocular side effects of psoriasis therapy.
Topics: Animals; Animals, Newborn; Child; Dogfish; Eye; Humans; Methoxsalen; Photochemotherapy; Psoriasis; R | 1980 |
Response of psoriatic nails to oral photochemotherapy.
Topics: Humans; Methoxsalen; Nail Diseases; Photochemotherapy; Psoriasis; Ultraviolet Rays | 1980 |
[Photochemotherapy of psoriasis using 8-MOP and UVA. Results of interval treatment. Clinical experiences from 6 dermatology hospitals].
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Radiography; Ultraviolet Therapy | 1980 |
Treatment of palmoplantar psoriasis with topical methoxsalen plus long-wave ultraviolet light.
Topics: Adolescent; Adult; Aged; Female; Follow-Up Studies; Foot Dermatoses; Hand Dermatoses; Humans; Male; | 1980 |
Determination of 8-methoxypsoralen in suction-blister fluid and serum by liquid chromatography.
Topics: Blister; Chromatography, High Pressure Liquid; Humans; Kinetics; Methoxsalen; Psoriasis; Suction | 1980 |
Toxic hepatitis from oral methoxsalen photochemotherapy (PUVA).
Topics: Administration, Oral; Chemical and Drug Induced Liver Injury; Female; Humans; Methoxsalen; Middle Ag | 1980 |
Plasma 8-methoxypsoralen concentrations in photochemotherapy of psoriasis.
Topics: Adult; Female; Half-Life; Humans; Kinetics; Male; Methoxsalen; Middle Aged; Photochemotherapy; Psori | 1981 |
[Free and bound 8-methoxypsoralen levels in 24-hour urine of psoriasis patients].
Topics: Chromatography, Thin Layer; Humans; Methoxsalen; Psoriasis | 1980 |
[PUVA therapy: decrease of the 8-methoxypsoralen level following local administration].
Topics: Administration, Topical; Adult; Female; Humans; Male; Methoxsalen; Pharmaceutical Vehicles; Photoche | 1980 |
Plasma levels of 8-methoxypsoralen after bath-PUVA for psoriasis: relationship to disease severity.
Topics: Administration, Cutaneous; Administration, Oral; Baths; Controlled Clinical Trials as Topic; Humans; | 1995 |
Plasma levels of 8-methoxypsoralen after topical paint PUVA on nonpalmoplantar psoriatic skin.
Topics: Administration, Topical; Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; PUV | 1994 |
British Photodermatology Group guidelines for PUVA.
Topics: 5-Methoxypsoralen; Cataract; Dermatitis, Atopic; Humans; Methoxsalen; Mycosis Fungoides; Psoriasis; | 1994 |
Photophysical alterations of erythrocyte membrane by 4,5',8-trimethyl psoralen: membrane response towards psoralen phototherapy.
Topics: Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Ethylmaleimide | 1994 |
PUVA treatment and choroidal malignant melanoma.
Topics: Adolescent; Choroid Neoplasms; Humans; Male; Melanoma; Methoxsalen; Psoriasis; PUVA Therapy | 1993 |
Determination of 8-methoxypsoralen kinetics: a relevant factor in the treatment of psoriasis by psoralen plus ultraviolet A therapy.
Topics: Adolescent; Adult; Aged; Child; Clinical Protocols; Female; Humans; Male; Methoxsalen; Middle Aged; | 1994 |
Antinuclear antibodies are not induced by PUVA treatment in patients with uncomplicated psoriasis.
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Antigens, Nuclear; Autoantigens; Cell Nucleolus; C | 1994 |
Patchy speckled bath PUVA pigmentation.
Topics: Adult; Baths; Drug Eruptions; Humans; Hyperpigmentation; Male; Methoxsalen; Psoriasis; PUVA Therapy; | 1993 |
High-performance liquid chromatographic determination of methoxsalen in plasma after liquid-solid extraction.
Topics: Chromatography, High Pressure Liquid; Griseofulvin; Humans; Methoxsalen; Psoriasis; PUVA Therapy | 1993 |
Serum free 5-methoxypsoralen fraction in health and psoriasis: relationship with human serum albumin concentration.
Topics: 5-Methoxypsoralen; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Methoxsalen; Middle Aged; P | 1993 |
Plasma levels of 8-methoxypsoralen after topical paint PUVA.
Topics: Administration, Topical; Adult; Aged; Eczema; Female; Humans; Male; Methoxsalen; Middle Aged; Pilot | 1993 |
Response of psoriasis to twice weekly PUVA.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Erythema; H | 1993 |
Phototesting and phototoxic side effects in bath PUVA.
Topics: Administration, Cutaneous; Baths; Dermatitis, Phototoxic; Humans; Methoxsalen; Psoriasis; PUVA Thera | 1993 |
PUVA erythemal sensitivity depends on plasma psoralen concentration and UVA sensitivity.
Topics: Adult; Aged; Dose-Response Relationship, Radiation; Erythema; Female; Humans; Male; Methoxsalen; Mid | 1993 |
Treatment of psoriasis with polyethylene sheet bath PUVA.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Baths; Cost-Benefit Analys | 1996 |
Inhibition of caffeine metabolism by 5-methoxypsoralen in patients with psoriasis.
Topics: 5-Methoxypsoralen; Adult; Aged; Caffeine; Central Nervous System Stimulants; Female; Humans; Male; M | 1996 |
Rectal suppositories of 8-methoxsalen produce fewer gastrointestinal side effects than the oral formulation.
Topics: Abdominal Pain; Administration, Oral; Administration, Rectal; Crystallization; Headache; Humans; Int | 1996 |
Permeation characteristics of 8-methoxypsoralen through human skin; relevance to clinical treatment.
Topics: Chemical Phenomena; Chemistry, Physical; Epidermis; Humans; In Vitro Techniques; Membranes; Methoxsa | 1996 |
5-Methoxypsoralen photoadduct formation: conversion of monoadducts to crosslinks.
Topics: 5-Methoxypsoralen; Animals; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; DN | 1995 |
Cutaneous carcinoma and PUVA lentigines in Thai patients treated with oral PUVA.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Arsenic; Bowen's Disease; Female; Follow | 1995 |
Bullous pemphigoid induced by PUVA therapy.
Topics: Aged; Aged, 80 and over; Autoantibodies; Basement Membrane; Complement C3; Epidermis; Fluorescent An | 1996 |
Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA). The PUVA Follow-Up Study.
Topics: Adult; Aged; Female; Humans; Male; Melanoma; Methoxsalen; Middle Aged; Odds Ratio; Prospective Studi | 1997 |
[Cream PUVA photochemotherapy].
Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Methoxsalen; Ointments; Phot | 1997 |
Bath-5-methoxypsoralen-UVA therapy for psoriasis.
Topics: 5-Methoxypsoralen; Administration, Oral; Adult; Aged; Baths; Female; Humans; Male; Methoxsalen; Midd | 1997 |
Impact of PUVA therapy on HIV viremia: a pilot study.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; HIV-1; Humans; Methoxsale | 1997 |
High-performance thin-layer chromatographic determination of 5-methoxypsoralen in serum from patients.
Topics: 5-Methoxypsoralen; Chromatography, Thin Layer; Humans; Methoxsalen; Psoriasis; PUVA Therapy; Reprodu | 1997 |
Generalized pustular psoriasis responsive to PUVA and oral cyclosporin therapy.
Topics: Acute Disease; Administration, Oral; Biopsy, Needle; Cyclosporine; Drug Therapy, Combination; Female | 1997 |
Comparison of 8-MOP aqueous bath and 8-MOP ethanolic lotion (Meladinine) in local PUVA therapy.
Topics: Administration, Cutaneous; Adult; Baths; Dose-Response Relationship, Drug; Female; Foot Dermatoses; | 1998 |
Effects of antipsoriatic therapies on hepatic microsomal enzyme activity in patients with psoriasis.
Topics: Administration, Topical; Anthralin; Anti-Inflammatory Agents; Antipyrine; Cytochrome P-450 Enzyme In | 1998 |
Merkel-cell carcinomas in patients treated with methoxsalen and ultraviolet A radiation.
Topics: Aged; Aged, 80 and over; Carcinoma, Merkel Cell; Female; Humans; Male; Methoxsalen; Photosensitizing | 1998 |
Trimethylpsoralen bath PUVA is a remittive treatment for psoriasis vulgaris. Evidence that epidermal immunocytes are direct therapeutic targets.
Topics: Antigens, CD; Antigens, CD1; B7-2 Antigen; CD3 Complex; Epidermis; Female; Humans; Lymphocyte Activa | 1998 |
PUVA-induced lymphocyte apoptosis: mechanism of action in psoriasis.
Topics: Apoptosis; Cells, Cultured; Flow Cytometry; Humans; Keratinocytes; Methoxsalen; Photosensitizing Age | 1999 |
Cancer incidence among Finnish psoriasis patients treated with 8-methoxypsoralen bath PUVA.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Baths; Carcinoma, Basal Cell; | 1999 |
Hand and foot PUVA soaks: an audit of the Massachusetts General Hospital's experience from 1994 to 1998.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Foot Dermatoses; Hand Dermatoses; Humans; | 1999 |
Carcinogenic risk of bath PUVA in comparison to oral PUVA therapy.
Topics: 5-Methoxypsoralen; Administration, Oral; Administration, Topical; Baths; DNA Adducts; Female; Humans | 1999 |
Hepatitis from 5-methoxypsoralen occurring in a patient with previous flucloxacillin hepatitis.
Topics: 5-Methoxypsoralen; Chemical and Drug Induced Liver Injury; Female; Floxacillin; Humans; Methoxsalen; | 1999 |
Pharmacokinetic behaviour of sublingually administered 8-methoxypsoralen for PUVA therapy.
Topics: Administration, Sublingual; Adult; Aged; Analysis of Variance; Excipients; Female; Humans; Male; Met | 2001 |
Phototherapy of psoriasis: comparative experience of different phototherapeutic approaches.
Topics: Administration, Topical; Adult; Anthralin; Anti-Inflammatory Agents; Baths; Calcitriol; Dermatologic | 2001 |
The risk of melanoma in association with long-term exposure to PUVA.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Female; Humans; Incidence; Male; Melanoma; Methoxsal | 2001 |
Acitretin therapy for palmoplantar pustulosis combined with UVA and topical 8-MOP.
Topics: Acitretin; Administration, Topical; Adult; Combined Modality Therapy; Female; Humans; Keratolytic Ag | 2001 |
Systemic allergic contact dermatitis to 8-methoxypsoralen (8-MOP).
Topics: Adult; Dermatitis, Allergic Contact; Diagnosis, Differential; Female; Humans; Methoxsalen; Patch Tes | 2001 |
[Acute generalized exanthematous pustulosis due to meladinine with positive patch tests].
Topics: Acute Disease; Aged; Biopsy; Drug Eruptions; Female; Humans; Methoxsalen; Psoriasis; PUVA Therapy; S | 2002 |
Can the immersion time of PUVA bath therapy be shortened?
Topics: Baths; Dose-Response Relationship, Drug; Erythema; Female; Follow-Up Studies; Humans; Immersion; Mal | 2002 |
Editorial: Light on psoriasis.
Topics: Administration, Oral; Humans; Methoxsalen; Psoriasis; Time Factors; Ultraviolet Therapy | 1975 |
Letter: Light on Psoriasis.
Topics: Administration, Oral; Anthracenes; Coumarins; Drug Therapy, Combination; Furans; Humans; Methoxsalen | 1975 |
Treatment of psoriasis with oral psoralens and longwave ultraviolet light. Therapeutic results and cytogenetic hazards.
Topics: Administration, Oral; Adult; Chromosome Aberrations; Female; Humans; Leukocytes; Male; Methoxsalen; | 1975 |
Photochemotherapy of psoriasis with relevance to 8-methoxypsoralen plasma level and low intensity irradiation.
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; Radiotherapy Dosage; Ultravi | 1977 |
The binding of 8-methoxypsoralen to nuclear DNA of UVA irradiated human fibroblasts in vitro.
Topics: Animals; Autoradiography; Binding Sites; Cell Nucleus; Cytoplasm; DNA; Fibroblasts; Guinea Pigs; Hum | 1977 |
The pigmentary response to photochemotherapy.
Topics: Adult; Aged; Female; Humans; Male; Melanocytes; Methoxsalen; Middle Aged; Photochemotherapy; Psorias | 1977 |
Treatment of resistant psoriasis with oral 8-methoxypsoralen and longwave ultraviolet light (PUVA). A treatment schedule and a follow-up study.
Topics: Follow-Up Studies; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Recurrence; Ultraviolet Therap | 1977 |
Sister chromatid exchanges in lymphocytes from psoriasis patients treated with 8-methoxypsoralen and longwave ultraviolet light.
Topics: Adolescent; Adult; Chromatids; Chromosomes, Human; Female; Humans; Lymphocytes; Male; Methoxsalen; M | 1978 |
Plasma levels of 8-methoxypsoralen and phototoxicity studies during PUVA treatment of psoriasis with meladinin tablets.
Topics: Adult; Aged; Drug Evaluation; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Pso | 1978 |
Serum levels of 8-methoxypsoralen 2 hours after oral administration.
Topics: Administration, Oral; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Time Factors | 1978 |
Ultrastructural changes in nuclei and nucleoli in psoriatic epidermis during and after PUVA therapy.
Topics: Adolescent; Adult; Cell Nucleolus; Cell Nucleus; Epidermis; Heterochromatin; Humans; Methoxsalen; Mi | 1978 |
DNA interstrand crosslinks visualized by electron microscopy in PUVA-treated psoriasis.
Topics: Adult; Aged; DNA; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Psoriasis; Skin | 1979 |
Antinuclear antibodies during Puva therapy.
Topics: Adult; Aged; Antibodies, Antinuclear; Female; Fluorescent Antibody Technique; Humans; Male; Methoxsa | 1979 |
Lack of dermal changes in uninvolved skin after photochemotherapy of psoriasis: biochemical studies.
Topics: Adolescent; Adult; Age Factors; Aged; Collagen; Female; Humans; Hydroxylysine; Hydroxyproline; Male; | 1979 |
Does photochemotherapy increase the risk of skin cancer?
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Methoxsalen; Photochemotherapy; Psoriasis; | 1979 |
Photochemotherapy for psoriasis.
Topics: Evaluation Studies as Topic; Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1979 |
Liver biopsy in PUVA-treated patients.
Topics: Adult; Female; Humans; Liver; Male; Methoxsalen; Mycosis Fungoides; Photochemotherapy; Psoriasis; Sk | 1979 |
Photochemotherapy and risk of skin cancer.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Neoplasms | 1979 |
Photochemotherapy and the risk of skin cancer.
Topics: Carcinogens; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Risk; Skin Neoplasms | 1979 |
[Inclusion of clinical-dermatological therapy into general practice? (author's transl)].
Topics: Family Practice; Humans; Keratosis; Methotrexate; Methoxsalen; Patient Care Team; Photochemotherapy; | 1979 |
[Experimental bases and primary trials of photochemotherapy of psoriasis by a non-cancerigenic monofunctional furocoumarin, 3-carbethoxypsoralen].
Topics: Animals; DNA; DNA, Mitochondrial; Furocoumarins; Humans; Methoxsalen; Mice; Photochemotherapy; Psori | 1979 |
[Therapeutic results of 8-methoxypsoralen (8-MOP) and UVR (ultraviolet rays)].
Topics: Acne Vulgaris; Adult; Aged; Eczema; Female; Humans; Male; Methoxsalen; Psoriasis; Skin Diseases; Ult | 1975 |
[Utilisation of photochemotherapy by UVA and locally applied psoralens (author's transl)].
Topics: Acne Vulgaris; Eczema; Humans; Methoxsalen; Mycosis Fungoides; Photochemotherapy; Psoriasis; Skin Di | 1977 |
Acne induced by PUVA treatment.
Topics: Acne Vulgaris; Adult; Humans; Male; Methoxsalen; Photochemotherapy; Psoriasis | 1977 |
Histopathologic changes in skin after photochemotherapy.
Topics: Evaluation Studies as Topic; Glycosaminoglycans; Humans; Methoxsalen; Photochemotherapy; Psoriasis; | 1977 |
Photoallergic dermatitis from 8-methoxypsoralen.
Topics: Adult; Drug Eruptions; Female; Humans; Methoxsalen; Photochemotherapy; Photosensitivity Disorders; P | 1978 |
Photochemotherapy for psoriasis--PUVA breaking through "the heartbreak".
Topics: Adult; Drug Eruptions; Erythema; Humans; Methoxsalen; Middle Aged; Photochemotherapy; Psoriasis; Ult | 1978 |
Contact allergy to methoxsalen.
Topics: Dermatitis, Contact; Drug Eruptions; Female; Humans; Methoxsalen; Middle Aged; Photochemotherapy; Ps | 1979 |
Photochemotherapy for psoriasis.
Topics: Adaptation, Psychological; Aged; Female; Humans; Massachusetts; Methoxsalen; Outpatient Clinics, Hos | 1979 |
Psoriasis and recent PUVA therapy.
Topics: Humans; Methoxsalen; Photochemistry; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1978 |
Development of acute myeloid leukaemia in a patient with psoriasis treated with oral 8-methoxypsoralen and longwave ultraviolet light.
Topics: Aged; Carcinogens; Female; Humans; Leukemia, Myeloid, Acute; Methoxsalen; Photochemotherapy; Psorias | 1979 |
Photochemotherapy of psoriasis (PUVA).
Topics: Administration, Oral; Adolescent; Erythema; Female; Humans; Methoxsalen; Nausea; Photochemotherapy; | 1979 |
Serum uric acid levels in untreated and PUVA-treated patients with psoriasis.
Topics: Furocoumarins; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy; Uric Acid | 1979 |
DNA in psoriatic epidermis.
Topics: DNA; Epidermis; Furocoumarins; Humans; Methoxsalen; Microscopy, Electron; Photochemotherapy; Psorias | 1979 |
[Photochemotherapy of psoriasis with oral 8-methoxypsoralen (author's transl)].
Topics: Administration, Oral; Adolescent; Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Photo | 1978 |
Effect of 8-methoxypsoralen plus UVA (PUVA) on lymphocyte transformation and T cells in psoriatic patients.
Topics: Adult; Aged; Female; Humans; Lymphocyte Activation; Male; Methoxsalen; Middle Aged; Photochemotherap | 1979 |
Normal T-lymphocyte function in psoriatic patients undergoing methoxsalen photochemotherapy.
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Psoriasis; T-Lymphoc | 1979 |
T lymphocyte E rosette function during photochemotherapy (PUVA) of psoriasis.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Rosette Formation; T-Lymphocytes; Time Factors | 1979 |
Transient impairment of peripheral blood lymphocyte function during PUVA therapy.
Topics: Adult; B-Lymphocytes; Humans; Leukocyte Count; Lymphocyte Activation; Lymphocytes; Methoxsalen; Midd | 1979 |
Quantification of HTLA-positive lymphocytes during oral photochemotherapy of psoriasis.
Topics: Administration, Oral; Adult; Antigens; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemothe | 1979 |
The psoralens. An historical perspective.
Topics: Coumarins; Egypt; Ficusin; History, 20th Century; History, Ancient; History, Medieval; History, Mode | 1977 |
Bullous pemphigoid induced by PUVA therapy. Is this the aetiology of the acral bullae produced during PUVA treatment?
Topics: Adult; Aged; Antibodies; Fluorescent Antibody Technique; Humans; Male; Methoxsalen; Pemphigus; Photo | 1978 |
Photochemotherapy (PUVA) of psoriasis using 3-carbethoxypsoralen, a non-carcinogenic compound in mice.
Topics: Animals; DNA, Fungal; Drug Evaluation, Preclinical; Female; Furocoumarins; Humans; Male; Methoxsalen | 1979 |
Effect of 8-methoxypsoralen plus UVA on psoriasis leukotactic factor.
Topics: Adult; Aged; Chemotaxis, Leukocyte; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherap | 1979 |
Photochemotherapy in psoriasis.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1979 |
Risk of cutaneous carcinoma in patients treated with oral methoxsalen photochemotherapy for psoriasis.
Topics: Administration, Oral; Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Follow-Up Studies; Hum | 1979 |
Risks and benefits of the treatment of psoriasis.
Topics: Administration, Oral; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Coal Tar; Furocoumar | 1979 |
Bowen's disease and squamous cell carcinoma. Occurrence in a patient with psoriasis after topical, systemic, and PUVA therapy.
Topics: Adult; Carcinoma, Squamous Cell; Coal Tar; Cocarcinogenesis; Glucocorticoids; Humans; Hydroxyurea; M | 1979 |
The effect of PUVA treatment on circulating lymphocytes.
Topics: Adult; Female; Humans; Lymphocyte Activation; Male; Methoxsalen; Middle Aged; Photochemotherapy; Pso | 1979 |
Serum concentration and phototoxic effect of methoxsalen in patients with psoriasis.
Topics: Adult; Humans; Methoxsalen; Photosensitivity Disorders; Psoriasis; Time Factors | 1979 |
Topical methoxsalen administration and sunlamp fluorescent irradiation in psoriasis.
Topics: Administration, Topical; Fluorescence; Humans; Male; Methoxsalen; Photochemotherapy; Psoriasis; Sunl | 1979 |
Initial photochemotherapy of psoriasis with orally administered 8-methoxypsoralen and longwave ultraviolet light (PUVA).
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; | 1979 |
[Psoriasis vulgaris--decrease of serum immune complexes following photochemotherapy (author's transl)].
Topics: Antigen-Antibody Complex; Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1979 |
Epidermal dystrophy. Occurrence after psoriasis therapy with psoralen and long-wave ultraviolet light.
Topics: Epidermis; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin; Skin Diseases | 1979 |
Melanin granula distribution and phagocytosis in psoriasis vulgaris after PUVA therapy.
Topics: Eosinophils; Humans; Mast Cells; Melanins; Methoxsalen; Phagocytes; Photochemotherapy; Plasma Cells; | 1979 |
Riboflavin status in PUVA patients.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Riboflavin Deficiency; Ultraviolet Therapy | 1979 |
PUVA suppresses the proliferative stimulus produced by stripping on hairless mice.
Topics: Animals; Autoradiography; Disease Models, Animal; DNA; Furocoumarins; Methoxsalen; Mice; Mice, Nude; | 1979 |
Skin cancer after PUVA treatment for psoriasis.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Neoplasms; Ultraviolet Therapy | 1979 |
Skin cancer after PUVA treatment for psoriasis.
Topics: Animals; Humans; Methoxsalen; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Photochemothe | 1979 |
Skin cancer after PUVA treatment for psoriasis.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Neoplasms; Ultraviolet Therapy | 1979 |
[Semen analysis under photochemotherapy (PUVA-therapy) (author's transl)].
Topics: Humans; Male; Methoxsalen; Photochemotherapy; Psoriasis; Semen; Spermatozoa | 1979 |
[Skin impedance and phoreographic index in psoriasis. Relationship with action kinetics of three treatments].
Topics: Anthralin; Electric Conductivity; Fluprednisolone; Humans; Keratins; Kinetics; Methoxsalen; Mitotic | 1979 |
[DNA-repair in lymphocytes after 8-MOP + UVA and UVC irradiation (author's transl)].
Topics: DNA Repair; Dose-Response Relationship, Radiation; Humans; In Vitro Techniques; Lymphocytes; Methoxs | 1979 |
Therapy of psoriasis with retinoid plus PUVA: clinical and histologic data.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin; Tretinoin; Vitamin A | 1979 |
Lymphocyte proliferation during PUVA therapy.
Topics: Adolescent; Adult; Aged; Antigens; Cell Division; Female; Humans; Lymphocytes; Male; Methoxsalen; Mi | 1979 |
An estimate of genetic risk from 8-methoxypsoralen photochemotherapy.
Topics: DNA; Humans; Male; Methoxsalen; Mutation; Photochemotherapy; Psoriasis; Risk; Spermatozoa | 1979 |
Polyploidization and hemiploidization induced by PUVA in vivo.
Topics: Cell Division; Cell Nucleus; Chromosome Aberrations; Epidermis; Fibroblasts; Humans; Meiosis; Methox | 1979 |
Clinical side-effects of long-wave ultraviolet light and oral 8-methoxypsoralen in patients treated for psoriasis.
Topics: Female; Hirsutism; Humans; Methoxsalen; Photochemotherapy; Pruritus; Psoriasis; Ultraviolet Therapy | 1979 |
[Disseminated granuloma annulare following puvatherapy].
Topics: Aged; Granuloma; Humans; Male; Methoxsalen; Photochemotherapy; Psoriasis; Skin Diseases | 1979 |
Comparison of crude coal tar and topical methoxsalen in treatment of psoriasis.
Topics: Coal Tar; Humans; Male; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1979 |
Photochemotherapy and psoriatic arthritis. A prospective study.
Topics: Arthritis; Female; Humans; Male; Methoxsalen; Photochemotherapy; Prospective Studies; Psoriasis; Spo | 1979 |
[Psoriasis and PUVA].
Topics: Humans; Methoxsalen; Neoplasms; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1979 |
Amyloid deposition after psoriasis therapy with psoralen and long-wave ultraviolet light.
Topics: Amyloidosis; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin; Skin Diseases | 1979 |
8-MOP plasma levels in PUVA problem cases with psoriasis.
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Psoriasis; Time Fact | 1979 |
Psoralen photochemotherapy of psoriasis.
Topics: Adult; Aged; DNA; Epidermis; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Psor | 1979 |
5-Methoxypsoralen (Bergapten) in photochemotherapy of psoriasis.
Topics: Drug Administration Schedule; Drug Evaluation; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Sk | 1979 |
Effect of PUVA on serum 25-OH vitamin D in psoriatics.
Topics: Humans; Hydroxycholecalciferols; Methoxsalen; Photochemotherapy; Psoriasis | 1979 |
Current status of oral PUVA therapy for psoriasis.
Topics: Administration, Oral; Adolescent; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet The | 1979 |
PUVA therapy status.
Topics: Carcinoma, Squamous Cell; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Neoplasms; Ultravi | 1979 |
[Treatment of psoriasis with long-wave ultraviolet rays combined with photosensitizing agents].
Topics: Adult; Animals; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Psoriasis; Rabbit | 1979 |
[Photochemotherapy and spermiogenesis].
Topics: Adult; Dose-Response Relationship, Drug; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; | 1979 |
[Impetigo herpetiformis and PUVA-treatment (author's transl)].
Topics: Administration, Oral; Adult; Female; Humans; Impetigo; Methoxsalen; Photochemotherapy; Pregnancy; Pr | 1979 |
[Peroral PUVA treatment of psoriasis].
Topics: Administration, Oral; Furocoumarins; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Radiotherapy | 1979 |
[Adverse effects in the treatment of psoriasis].
Topics: Atrophy; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Diseases; Ultraviolet Therapy | 1979 |
[Treatment of psoriasis by photochemotherapy using a Soviet long-wave ultraviolet unit].
Topics: Adult; Chronic Disease; Female; Furocoumarins; Humans; Male; Methoxsalen; Middle Aged; Photochemothe | 1979 |
Inhibition of human blood platelet aggregation by photochemotherapy in vitro and in vivo.
Topics: Adult; Anthralin; Collagen; Humans; Methoxsalen; Photochemotherapy; Platelet Aggregation; Psoriasis; | 1979 |
Photochemotherapy for psoriasis remission times. Psoralens and UV-A and combined photochemotherapy with anthralin.
Topics: Adolescent; Adult; Aged; Anthracenes; Anthralin; Child; Drug Therapy, Combination; Female; Humans; M | 1979 |
[Could PUVA therapy and solar lights provoke ocular lesions?].
Topics: Animals; Cataract; Eye Protective Devices; Eyeglasses; Guinea Pigs; Humans; Lens, Crystalline; Metho | 1979 |
Photosensitizers and radiosensitizers in dermatology and oncology.
Topics: Brain Neoplasms; DNA; Humans; Methoxsalen; Metronidazole; Misonidazole; Mycosis Fungoides; Photochem | 1979 |
Clinical results of photochemotherapy. The Cleveland Clinic experience.
Topics: Evaluation Studies as Topic; Humans; Methoxsalen; Middle Aged; Mycosis Fungoides; Ohio; Photochemoth | 1977 |
Comparison of phototherapy systems for photochemotherapy.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Radiotherapy Dosage; Time Factors; Ultraviolet Th | 1977 |
Essentials for PUVA therapy. Guidelines for photochemotherapy.
Topics: Evaluation Studies as Topic; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Radiation Protection | 1977 |
[New UVA-high-intensity-standing-box--experiences in oral 8-MOP-UVA therapy].
Topics: Humans; Methoxsalen; Photochemotherapy; Posture; Psoriasis; Ultraviolet Therapy | 1977 |
Photochemotherapy for psoriasis.
Topics: Administration, Oral; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1977 |
Toxic effects of 8-methoxypsoralen on lymphocyte division.
Topics: Cell Division; Cells, Cultured; Humans; In Vitro Techniques; Lymphocytes; Methoxsalen; Psoriasis; Ul | 1977 |
[Unusual adverse effects of oral photochemotherapy (PUVA-therapy) in psoriasis].
Topics: Adult; Female; Humans; Hypertrichosis; Light; Male; Methoxsalen; Middle Aged; Nails; Photochemothera | 1977 |
Sister chromatid exchanges in lymphocytes of psoriatics after treatment with 8-methoxypsoralen and long wave ultraviolet radiation.
Topics: Chromatids; Humans; Lymphocytes; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1977 |
[Oral photochemotherapy of psoriasis, clinical findings in 100 patients].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Male; Methoxsalen; Middle Aged; Ph | 1977 |
5-S-cysteinyldopa excretion after treatment with 8-methoxypsoralen and UVA light.
Topics: Adult; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Male; Melanocytes; Methoxsalen; Middle | 1978 |
Dermatology.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy; United States | 1978 |
[Experience with photochemotherapy with 8-methoxypsoralene by mouth and long-wave ultraviolet light (PUVA-treatment) in psoriasis].
Topics: Adolescent; Adult; Aged; Evaluation Studies as Topic; Female; Humans; Male; Methoxsalen; Middle Aged | 1978 |
A new apparatus for the delivery of high intensity UVA and UVA+UVB irradiation, and some dermatological applications.
Topics: Acrodermatitis; Adult; Aged; Erythema; Erythropoiesis; Female; Humans; Male; Methoxsalen; Photochemo | 1978 |
[Photochemical treatment of psoriasis].
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1978 |
Woronoff's rings with PUVA therapy.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Diseases; Ultraviolet Therapy | 1978 |
Photochemotherapy of psoriasis (PUVA) without specialized equipment.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1978 |
Augmentation of oral methoxsalen-photochemotherapy with an oral retinoic acid derivative.
Topics: Dose-Response Relationship, Radiation; Drug Therapy, Combination; Follow-Up Studies; Humans; Methoxs | 1978 |
Photochemotherapy of psoriasis.
Topics: Female; Humans; Methoxsalen; Photochemotherapy; Pregnancy; Psoriasis; Recurrence; Time Factors | 1978 |
Treatment of psoriasis with orally administered 8-methoxypsoralen and long-wavelength ultraviolet radiation.
Topics: Administration, Oral; Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy | 1978 |
Serum uric acid levels in untreated and PUVA-treated patients with psoriasis.
Topics: Cholesterol; DNA; Epidermis; Humans; Methoxsalen; Obesity; Photochemotherapy; Psoriasis; Purines; Tr | 1978 |
PUVA: a review of ultraviolet dosimetry.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Radiation Dosage; Ultraviolet Therapy | 1978 |
PUVA.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1978 |
[Photochemotherapy of psoriasis by means of PUVA].
Topics: Chemical Phenomena; Chemistry; Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1978 |
[Experience with the photochemotherapy of psoriasis in Lausanne (author's transl)].
Topics: Administration, Oral; Cortisone; France; Humans; Methotrexate; Methoxsalen; Photochemotherapy; Psori | 1978 |
[Treatment of psoriasis with 8-methoxypsoralen and ultraviolet A rays].
Topics: Adolescent; Adult; Aged; Drug Evaluation; Humans; Methoxsalen; Middle Aged; Photochemotherapy; Psori | 1978 |
Trioxsalen vs methoxsalen in the treatment of psoriasis.
Topics: Coumarins; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Trioxsalen | 1978 |
Dark effect of 8-methoxypsoralen (8-MOP) on lymphocytes.
Topics: Cell Count; Humans; Lymphocytes; Methoxsalen; Photic Stimulation; Photochemotherapy; Psoriasis; Rose | 1978 |
Serum levels of 8-methoxypsoralen in psoriasis patients using a new fluorodensitometric method.
Topics: Chromatography, Thin Layer; Densitometry; Fluorescence; Humans; Methoxsalen; Psoriasis | 1978 |
Decrease in neutrophils observed in vivo in psoriatics after PUVA therapy.
Topics: Female; Humans; Male; Methoxsalen; Neutrophils; Photochemotherapy; Psoriasis | 1978 |
[May PUVA-therapy be dangerous?].
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1978 |
[Photochemotherapy with 8-methoxypsoralen and longwave ultraviolet light. V. Experiences with a new treatment unit (author's transl)].
Topics: Adult; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Psoriasis; Ultraviolet The | 1978 |
[Use of 8-methoxypsoralen and ultraviolet A rays in the treatment of psoriasis].
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1978 |
[Photochemotherapy, a new therapeutic method in psoriasis].
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1978 |
Committee on Drugs. PUVA: A caution.
Topics: Child; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1978 |
PUVA treatment of psoriasis.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1978 |
[Light microscopy studies in the photochemotherapy of psoriasis vulgaris].
Topics: Humans; Methods; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1978 |
Oral methoxsalen photochemotherapy of recalcitrant dermatoses of the palms and soles.
Topics: Adolescent; Adult; Aged; Eczema; Female; Foot Dermatoses; Hand Dermatoses; Humans; Methoxsalen; Midd | 1978 |
[PUVA-treatment of pustular psoriasis of the von Zumbusch type (author's transl)].
Topics: Adult; Female; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1978 |
[Recommendation for the construction of a photochemotherapy device].
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1978 |
Acute effect of 8-methoxypsoralen and ultraviolet light on sister chromatid exchange.
Topics: Chromatids; Humans; Male; Methoxsalen; Mitosis; Mutagens; Photochemotherapy; Psoriasis; Ultraviolet | 1978 |
Preleukaemia (haemopoietic dysplasia) developing in a patient with psoriasis treated with 8-methoxypsoralen and ultraviolet light (PUVA treatment).
Topics: Aged; Blood Cell Count; Bone Marrow; Chromosome Aberrations; Chromosomes, Human, 6-12 and X; Humans; | 1978 |
[Photochemotherapy of psoriasis by 8-methoxypsoralen in a combination with long-wave ultraviolet radiation (author's transl)].
Topics: Adult; Female; Humans; Male; Methoxsalen; Photochemotherapy; Psoriasis | 1978 |
Generalized pustular psoriasis precipitated by lithium carbonate.
Topics: Adult; Bipolar Disorder; Female; Humans; Lithium; Methotrexate; Methoxsalen; Photochemotherapy; Psor | 1978 |
Stimulation of lymphocytes in patients with psoriasis under photochemotherapy. A study of lymphocyte transformation.
Topics: Adult; Aged; Female; Humans; Lymphocyte Activation; Male; Methoxsalen; Middle Aged; Photochemotherap | 1978 |
Evaluation of PUVA, topical corticosteroids and the combination of both in the treatment of psoriasis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Child; Humans; Methoxsalen; Middle Aged; Occlusive | 1978 |
Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis.
Topics: Adolescent; Adult; Aged; Baths; Blister; Dermatitis, Contact; Female; Furocoumarins; Humans; Male; M | 1978 |
[Phototherapy of psoriasis using emitter UV 300].
Topics: Female; Humans; Male; Methoxsalen; Psoriasis; Ultraviolet Therapy | 1978 |
[Photochemotherapy and cataract formation].
Topics: Animals; Cataract; Guinea Pigs; Humans; Lens, Crystalline; Methoxsalen; Mice; Photochemotherapy; Pso | 1978 |
Photochemotherapy in psoriasis: the first six months in Australia.
Topics: Australia; Darier Disease; Dermatitis; Edema; Erythema; Humans; Methoxsalen; Photochemotherapy; Prur | 1979 |
PUVA-induced bullous pemphigoid.
Topics: Aged; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; Skin Diseases, Vesiculobullous; Ultraviolet | 1976 |
[Treatment of psoriasis (author's transl)].
Topics: Coumarins; Ficusin; Furocoumarins; Humans; Methoxsalen; Mitosis; Psoriasis; Skin; Structure-Activity | 1976 |
Photochemotherapy for psoriasis with orally administered methoxsalen.
Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; Dose-Response Relationship, | 1976 |
Psoriasis: clinical aspects and management.
Topics: Administration, Topical; Age Factors; Azauridine; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine | 1976 |
The human peripheral lymphocyte--a model system for studying the combined effect of psoralen plus black light.
Topics: DNA; Humans; Lymphocyte Activation; Lymphocytes; Methoxsalen; Psoriasis; Ultraviolet Rays; Ultraviol | 1977 |
[Histopathology and histochemistry of psoriasis under photochemotherapy (author's transl)].
Topics: Histocytochemistry; Humans; Melanocytes; Methoxsalen; Psoriasis; Skin; Skin Pigmentation; Ultraviole | 1977 |
Topical methoxsalen and blacklight in the treatment of psoriasis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Blister; Child; Female; Humans; Male; Methoxsalen; | 1977 |
Psoralens.
Topics: Coumarins; Ficusin; Furocoumarins; Humans; Methoxsalen; Psoriasis | 1977 |
PUVA treatment for psoriasis using metal halide quartz lamps.
Topics: Humans; Methoxsalen; Psoriasis; Ultraviolet Therapy | 1977 |
Oral methoxsalen photochemotherapy for the treatment of psoriasis: a cooperative clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; Erythema; Female; Humans; Ma | 1977 |
Photochemotherapy in the treatment of psoriasis.
Topics: Adolescent; Adult; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemistry; Psoriasis; Ultrav | 1977 |
PUVA: using filtered sunlight as an energy source.
Topics: Adolescent; Adult; Female; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; Sunlight; Ultraviolet | 1977 |
Sister chromatid exchanges in photochemotherapy.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anthralin; Child; Chromatids; Chromosome Aberrations; DNA Repa | 1977 |
Effects of 8-methoxypsoralen (8-MOP) and UVA on human lymphocytes.
Topics: Humans; Lymphocyte Activation; Lymphocytes; Methoxsalen; Photochemotherapy; Psoriasis; Rosette Forma | 1977 |
Serum level profiles of 8-methoxypsoralen after oral administration.
Topics: Administration, Oral; Humans; Methoxsalen; Psoriasis | 1977 |
Photochemotherapy for pustular psoriasis (von Zumbusch).
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Methoxsalen; Photochemotherapy; Psoriasi | 1977 |
A dosimeter for long wave ultraviolet radiation.
Topics: Dose-Response Relationship, Radiation; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviole | 1977 |
[Photochemotherapy with 8-methoxypsoralen and UVA. III. Fluorescent microscopy studies of binding and transport of 8-MOP in the human skin].
Topics: Binding Sites; Humans; Methoxsalen; Microscopy, Fluorescence; Photochemotherapy; Psoriasis; Skin | 1977 |
[Photochemotherapy: a new possibility in the treatment of psoriasis (author's transl)].
Topics: Adult; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Psoriasis; Ultraviolet The | 1977 |
[UV-therapy of psoriasis. Half-side comparison between oral photochemotherapy (PUVA) and selective UV-phototherapy (SUP)].
Topics: Evaluation Studies as Topic; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1977 |
Leukocyte chemotaxis after in vitro treatment with 8-methoxypsoralen and UVA.
Topics: Chemotaxis, Leukocyte; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Ultraviolet Rays | 1977 |
[The treatment of psoriasis with oral 8-methoxypsoralen and long-wave ultraviolet light].
Topics: Humans; Methoxsalen; Psoriasis; Ultraviolet Therapy | 1976 |
Therapy of psoriasis 1975.
Topics: Administration, Topical; Adrenal Cortex Hormones; Azauridine; Depression, Chemical; Ficusin; Humans; | 1976 |
[Treatment of psoriasis with 8-methoxypsoralen and black-light (author's transl)].
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Phototherapy; Psoriasis; Ultraviolet Th | 1976 |
[Technical experience with 8-methoxypsoralen photochemotherapy in common psoriasis].
Topics: Administration, Oral; Administration, Topical; Evaluation Studies as Topic; Female; Humans; Male; Me | 1976 |
[Photochemotherapy of psoriasis].
Topics: Humans; Methoxsalen; Psoriasis; Ultraviolet Therapy | 1976 |
[Treatment of psoriasis with 8-methoxypsoralen and long-wave ultraviolet light].
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; Ultraviolet Ther | 1976 |
[Therapy of psoriasis vulgaris with ultraviolet rays].
Topics: Heliotherapy; Humans; Methoxsalen; Phototherapy; Psoriasis; Ultraviolet Therapy | 1976 |
[Photochemotherapy of psoriasis with 8-methoxypsoralen and ultraviolet light. I. Radiation equipment].
Topics: Humans; Methoxsalen; Psoriasis; Ultraviolet Therapy | 1976 |
8-methoxypsoralen and UVA promote sister-chromatid exchanges.
Topics: Cells, Cultured; Chromatids; DNA Repair; Humans; Lymphocytes; Methoxsalen; Psoriasis; Ultraviolet Ra | 1976 |
Photochemotherapy (PUVA) and psoriasis: comparison of 8-MOP and 8-MOP/5-MOP.
Topics: Coumarins; Female; Ficusin; Furocoumarins; Humans; Male; Methoxsalen; Phototherapy; Psoriasis; Ultra | 1976 |
[Changes in enzyme activities during photochemotherapy. Studies on pure glucose-6-phosphate dehydrogenase and on homogenates of human skin].
Topics: Aspartate Aminotransferases; Glucosephosphate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenas | 1976 |
[Therapy of psoriasis].
Topics: Coumarins; Humans; Methoxsalen; Psoriasis; Sunlight; Trioxsalen; Ultraviolet Therapy | 1976 |
[Treatment with 8-methoxypsoralen and long-wave ultraviolet light. Psoriasis on the palms and soles and pustulosis palmaris and plantaris].
Topics: Adult; Aged; Drug Evaluation; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; M | 1976 |
[Clinical experience with the 8-methoxypsoralen-UVA therapy (photochemotherapy) of psoriasis].
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Follow-Up Studies; Humans; M | 1976 |
[Photochemotherapy of psoriasis using 8-methoxypsoralen and UVA. II. Binding of the photosensitizator to protein].
Topics: Cell Membrane Permeability; Humans; Methoxsalen; Protein Binding; Psoriasis; Ultraviolet Therapy | 1976 |
Treatment of psoriasis.
Topics: Adrenal Cortex Hormones; Anthralin; Coal Tar; Humans; Methotrexate; Methoxsalen; Psoriasis; Ultravio | 1976 |
[Pustular psoriasis (Zumbusch) treated with 8-methoxypsoralen phototherapy (author's transl)].
Topics: Adult; Child, Preschool; Female; Humans; Methoxsalen; Psoriasis; Ultraviolet Therapy | 1975 |
Psoriasis and phototherapy.
Topics: Carcinogens; Humans; Methoxsalen; Psoriasis; Ultraviolet Therapy | 1975 |
Editorial: Photochemotherapy for psoriasis.
Topics: Animals; Chronic Disease; DNA Repair; Guinea Pigs; Humans; Methoxsalen; Mice; Psoriasis; Ultraviolet | 1975 |
Psoralens for psoriasis.
Topics: Adolescent; Adult; Anthralin; Coumarins; Ficusin; Humans; Methoxsalen; Middle Aged; Psoriasis; Triox | 1975 |
[Treatment of psoriasis with UV-light, tar and psoralens].
Topics: Coal Tar; Coumarins; Humans; Methoxsalen; Psoriasis; Trioxsalen; Ultraviolet Therapy | 1975 |
[Photochemotherapy of psoriasis: clinical experiences with 152 patients (author's transl)].
Topics: Adolescent; Adult; Aged; Child; Humans; Methoxsalen; Middle Aged; Psoriasis; Remission, Spontaneous; | 1975 |
[Treatment of psoriasis. New possibility of psoriasis treatment using long-wave UV light and a photosensitizer].
Topics: Female; Humans; Male; Methods; Methoxsalen; Psoriasis; Recurrence; Remission, Spontaneous; Ultraviol | 1975 |
[8-Methoxypsoralen phototherapy of psoriasis vulgaris (author's transl)].
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; Ultraviol | 1975 |
Letter: Photochemotherapy using ordinary black light.
Topics: Humans; Male; Methoxsalen; Phototherapy; Psoriasis | 1976 |
Simplification of local therapy of psoriasis with 8-methoxypsoralen. Methods and initial results.
Topics: Erythema; Evaluation Studies as Topic; Female; Humans; Male; Methoxsalen; Oils; Ointment Bases; Pigm | 1976 |
Editorial: Photochemotherapy of psoriasis.
Topics: Humans; Methoxsalen; Psoriasis; Sunlight; Ultraviolet Therapy | 1976 |
Proceedings: Photochemotherapy. A study of its efficacy in fifty patients suffering from psoriasis and other dermatoses.
Topics: Humans; Methoxsalen; Mycosis Fungoides; Parapsoriasis; Psoriasis; Skin Neoplasms; Ultraviolet Therap | 1976 |
Proceedings: Effects and side-effects of 8-methoxypsoralen-blacklight-therapy in more than 1500 patients.
Topics: Humans; Methoxsalen; Psoriasis; Skin Diseases; Ultraviolet Therapy | 1976 |
A review of the 1992 annual meeting of the British Society for Investigative Dermatology.
Topics: Genes, p53; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Diseases; Vitiligo | 1992 |
8-MOP vs 5-MOP.
Topics: 5-Methoxypsoralen; Clinical Trials as Topic; Humans; Methoxsalen; Psoriasis | 1992 |
Immunohistochemical study on the pattern of 50 kd cytokeratin in psoriasis.
Topics: Administration, Topical; Adolescent; Adult; Anthralin; Anti-Inflammatory Agents; Betamethasone; Epid | 1992 |
Effect of psoralen and ultraviolet A on platelet functioning: an in vitro and in vivo study.
Topics: Adenosine Diphosphate; Humans; In Vitro Techniques; Methoxsalen; Platelet Aggregation; Psoriasis; PU | 1992 |
Time course of activity of topical 8-methoxypsoralen on palmoplantar skin.
Topics: Administration, Topical; Adult; Baths; Female; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; PU | 1992 |
Metabolism of the anti-psoriatic agent 5-methoxypsoralen in humans: comparison with rat and dog.
Topics: 5-Methoxypsoralen; Adult; Animals; Bile; Cecum; Chromatography, High Pressure Liquid; Dogs; Feces; G | 1992 |
The history of photochemotherapy.
Topics: History, 20th Century; History, Medieval; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Di | 1991 |
Bath-water delivery of 8-methoxypsoralen therapy for psoriasis.
Topics: Adult; Baths; Female; Humans; Male; Methoxsalen; Patient Acceptance of Health Care; Psoriasis; PUVA | 1991 |
Allergic contact and photocontact dermatitis due to psoralens in patients with psoriasis treated with topical PUVA.
Topics: Adult; Dermatitis, Contact; Female; Furocoumarins; Humans; Incidence; Male; Methoxsalen; Middle Aged | 1991 |
The relationship between plasma psoralen concentration and psoralen-UVA erythema.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiat | 1991 |
[Influence of retinoids on the bioavailability of methoxy-8-psoralen].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biological Availability; Drug Interactions; Etretinate; | 1991 |
8-Methoxypsoralen bath PUVA clears psoriasis after failure of oral PUVA.
Topics: Humans; Methoxsalen; Psoriasis; PUVA Therapy | 1990 |
[8-MOP serum level profile following administration of Geroxalen to patients with psoriasis and a control group].
Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Male; Methoxsalen; Middle Aged; Psoriasis | 1990 |
[8-methoxypsoralen serum content of problem patients in PUVA therapy].
Topics: Humans; Methoxsalen; Psoriasis; PUVA Therapy | 1990 |
6-Methylangelicins: new monofunctional photochemotherapeutic agents for psoriasis.
Topics: Animals; DNA; Female; Furocoumarins; Guinea Pigs; Humans; Male; Methoxsalen; Mice; Mice, Inbred Stra | 1990 |
[Late results of photochemotherapy of patients with psoriasis].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Chronic Disease; Drug Therapy, Combination; Female; Foll | 1990 |
[Pharmacokinetic comparison of 3 8-methoxypsoralen preparations and clinical aspects].
Topics: Capsules; Humans; Metabolic Clearance Rate; Methoxsalen; Psoriasis; PUVA Therapy; Tablets | 1990 |
Interaction between 8-methoxypsoralen and phenytoin. Consequence for PUVA therapy.
Topics: Drug Interactions; Epilepsy; Female; Humans; Methoxsalen; Middle Aged; Phenytoin; Psoriasis; PUVA Th | 1985 |
PUVA therapy for photosensitive psoriasis.
Topics: Female; Humans; Male; Methoxsalen; Middle Aged; Photosensitivity Disorders; Psoriasis; PUVA Therapy; | 1987 |
Autoradiographic study of the effects of psoralen and ultraviolet light on DNA, RNA and protein synthesis in cultured keratinocytes and psoriatic skin.
Topics: Animals; Autoradiography; Cells, Cultured; DNA; Guinea Pigs; Humans; Keratinocytes; Methoxsalen; Pro | 1988 |
A comparison of the dose-response relationship for psoralen-UVA erythema and UVB erythema.
Topics: Adult; Aged; Dose-Response Relationship, Radiation; Humans; Methoxsalen; Middle Aged; Photosensitivi | 1989 |
A modified dosage schedule for increased efficiency in PUVA treatment of psoriasis.
Topics: Humans; Methoxsalen; Psoriasis; PUVA Therapy; Recurrence; Time Factors; Ultraviolet Rays | 1989 |
8-Methoxypsoralen-DNA adducts in patients treated with 8-methoxypsoralen and ultraviolet A light.
Topics: Antibodies, Monoclonal; Biopsy; Chromatography, High Pressure Liquid; DNA Damage; Enzyme-Linked Immu | 1989 |
Oral methoxsalen photochemotherapy for the treatment of psoriasis: a cooperative clinical trial. 1977.
Topics: Administration, Oral; History, 20th Century; Humans; Methoxsalen; Photochemotherapy; Psoriasis | 1989 |
[Experience in the photochemotherapy of psoriasis with rectal administration of the photosensitizer].
Topics: Administration, Oral; Adolescent; Adult; Drug Evaluation; Female; Follow-Up Studies; Humans; Male; M | 1989 |
Melanonychia induced by systemic photochemotherapy.
Topics: 5-Methoxypsoralen; Adolescent; Female; Humans; Male; Methoxsalen; Middle Aged; Nail Diseases; Pigmen | 1989 |
Palmoplantar psoriasis: experience with 8-methoxypsoralen soaks plus ultraviolet A with the use of a high-output metal halide device.
Topics: Adult; Aged; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; Middle Aged; Psori | 1989 |
Density of epidermal Langerhans cells in psoriasis patients treated with an aromatic retinoid (RO 10-9359). An immunoperoxidase study using anti-T6 and anti-Ia monoclonal antibodies.
Topics: Adult; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Cell Count; Etretinate; Hist | 1986 |
An investigation of the ability of antipsoriatic drugs to inhibit calmodulin activity: a possible mode of action of dithranol (anthralin).
Topics: Animals; Anthracenes; Anthralin; Calmodulin; Cattle; Coal Tar; Etretinate; Hydrocortisone; In Vitro | 1986 |
Comparison of the relative therapeutic efficacy of 7-methyl pyridopsoralen and 8-methoxypsoralen in photochemotherapy in psoriasis treatment.
Topics: Adult; Aged; Erythema; Female; Furocoumarins; Humans; Male; Methoxsalen; Middle Aged; Photochemother | 1988 |
Detection and quantification of 8-methoxypsoralen-DNA adducts.
Topics: Animals; DNA; Flow Cytometry; Fluorescent Antibody Technique; Humans; Lymphoma; Methoxsalen; Mice; P | 1988 |
[Photochemotherapy in vitro--direct effect on epidermal lectin-binding of psoriatic and normal skin].
Topics: Epidermis; Humans; In Vitro Techniques; Methoxsalen; Photochemotherapy; Psoriasis; Receptors, Mitoge | 1988 |
Comparative pharmacokinetics of 8-MOP in serum and in suction blister fluid.
Topics: Adult; Aged; Aged, 80 and over; Blister; Female; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; | 1988 |
[Comparative characteristics of the results of photochemotherapy with the external use of psoberan in patients with psoriasis].
Topics: Administration, Oral; Baths; Chronic Disease; Drug Combinations; Drug Evaluation; Ficusin; Furocouma | 1988 |
Incidence of skin cancer in Japanese psoriatic patients treated with either methoxsalen phototherapy, Goeckerman regimen, or both therapies. A 10-year follow-up study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Follow-Up Studies; Humans; Jap | 1988 |
Bronchoconstriction due to 8-methoxypsoralen.
Topics: Asthma; Humans; Male; Methoxsalen; Middle Aged; Peak Expiratory Flow Rate; Psoriasis; PUVA Therapy | 1988 |
Photopheresis--extracorporeal irradiation of 8-MOP containing blood--a new therapeutic modality.
Topics: Combined Modality Therapy; Extracorporeal Circulation; Humans; Lymphoma; Methoxsalen; Plasmapheresis | 1987 |
Combination therapy of oral methoxypsoralen: photochemotherapy (PUVA) and an aromatic retinoid (etretinate, tigason) in the treatment of psoriasis.
Topics: Administration, Oral; Adolescent; Adult; Combined Modality Therapy; Etretinate; Female; Humans; Male | 1986 |
Photobiological activity of certain pyranocoumarin derivatives: potential agents for the photochemotherapy of psoriasis.
Topics: Animals; Benzopyrans; Coumarins; DNA; Escherichia coli; Guinea Pigs; Methoxsalen; Mutagenicity Tests | 1986 |
Methoxsalen is a potent inhibitor of the metabolism of caffeine in humans.
Topics: Adult; Biotransformation; Caffeine; Female; Humans; Male; Metabolic Clearance Rate; Methoxsalen; Mid | 1987 |
Differential effects of treatment with UV-light (365 nm) and 8-methoxypsoralen on chromosomes of healthy persons and psoriatic patients.
Topics: Chromosomes, Human; Humans; Methoxsalen; Psoriasis; PUVA Therapy; Ultraviolet Rays | 1986 |
[Testing the monooxygenase enzyme system of the liver using the antipyrine test in psoriasis patients].
Topics: 5-Methoxypsoralen; Adolescent; Adult; Antipyrine; Female; Ficusin; Furocoumarins; Humans; Male; Meth | 1986 |
Topical (bathwater) PUVA therapy.
Topics: Administration, Topical; Baths; Humans; Methoxsalen; Psoriasis; PUVA Therapy | 1987 |
Anthralin minute entire skin treatment: a follow-up and comparison with methoxsalen plus ultraviolet light.
Topics: Adult; Anthralin; Female; Humans; Male; Methoxsalen; Middle Aged; Psoriasis; PUVA Therapy | 1987 |
Acute myelomonocytic leukaemia developing in a patient with psoriasis treated with oral 8-methoxypsoralen and longwave ultraviolet light.
Topics: Humans; Leukemia, Myeloid, Acute; Male; Methoxsalen; Middle Aged; Photochemotherapy; Psoriasis; PUVA | 1985 |
Comparison of bioavailability and phototoxicity of two oral preparations of 5-methoxypsoralen.
Topics: 5-Methoxypsoralen; Administration, Oral; Adult; Aged; Biological Availability; Capsules; Erythema; F | 1985 |
[Psoriasis phototherapy. Antipsoriatic efficacy of 8-methoxypsoralen and tar baths].
Topics: Administration, Topical; Adult; Aged; Baths; Coal Tar; Female; Humans; Male; Methoxsalen; Middle Age | 1985 |
Lenticular psoralen photoproducts and cataracts of a PUVA-treated psoriatic patient.
Topics: Adult; Cataract; Humans; Lens, Crystalline; Male; Methoxsalen; Photochemotherapy; Psoriasis; PUVA Th | 1985 |
Editorial: Photochemotherapy of psoriasis.
Topics: Cell Division; DNA; Humans; Methoxsalen; Psoriasis; Skin; Ultraviolet Therapy | 1974 |
[Meladinin and black-light treatment of psoriasis].
Topics: Humans; Methoxsalen; Psoriasis; Ultraviolet Therapy | 1974 |
Resistant psoriasis. Combined methoxsalen-anthralin therapy.
Topics: Adult; Anthracenes; Drug Synergism; Humans; Male; Methoxsalen; Middle Aged; Ointments; Psoriasis; So | 1973 |
[Dermatological therapy of dermatoses using long-wave UV following methoxsalen photosensitization of the skin. First results in psoriasis vulgaris].
Topics: Adolescent; Adult; Aged; Deoxyribonucleases; Humans; Methoxsalen; Photosensitivity Disorders; Psoria | 1973 |
Combined 8-methoxypsoralen and black light therapy of psoriasis. Technique and results.
Topics: Adolescent; Adult; Dermatitis; Foot; Hand; Humans; Male; Methods; Methoxsalen; Middle Aged; Psoriasi | 1974 |
[Combined oral meladinine and ultraviolet rays in the treatment of psoriasis. (Preliminary note)].
Topics: Humans; Khellin; Male; Methoxsalen; Middle Aged; Psoriasis; Ultraviolet Therapy | 1967 |