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methoxsalen and Neoplasms

methoxsalen has been researched along with Neoplasms in 17 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Three phototherapeutic regimens with photosensitization are now used in dermatology: PUVA (psoralen + UVA), TUV (crude coaltar + UV), PRT (phototherapy with hematoporphyrin derivative)."2.37[Problems posed by the therapeutic use of photosensitizers in dermatology]. ( Amblard, P; Beani, JC; Reymond, JL, 1986)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199013 (76.47)18.7374
1990's1 (5.88)18.2507
2000's0 (0.00)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Mirzaei, SA1
Gholamian Dehkordi, N1
Ghamghami, M1
Amiri, AH1
Dalir Abdolahinia, E1
Elahian, F1
PATHAK, MA1
DANIELS, F1
HOPKINS, CE3
FITZPATRICK, TB1
HAKIM, RE1
GRIFFIN, AC2
KNOX, JM1
MACDONALD, EJ2
SMITH, L1
GARRETT, H1
BLACK, GL1
BELISARIO, JC1
DAVIS, CT1
VERMEL, EM1
TSETLIN, AL1
Schottenfeld, D1
Urbach, F2
Forbes, PD2
Davies, RE2
Nearn, MR1
Wolff, K1
Santamaria, L1
Arnaboldi, A1
Daffara, P1
Bianchi, A1
Sieber, SM1
Adamson, RA1
Strauss, RG1
Beani, JC1
Amblard, P1
Reymond, JL1

Reviews

5 reviews available for methoxsalen and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Cancer risks of medical treatment. Part II: potentially carcinogenic medications in current use.
    Clinical bulletin, 1981, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents; Contraceptives, Oral; Estrogens; Humans; Methoxsalen; Neoplasms; Phe

1981
Modification of photocarcinogenesis by chemical agents.
    Journal of the National Cancer Institute, 1982, Volume: 69, Issue:1

    Topics: Animals; Carcinogens; Dose-Response Relationship, Radiation; Mechlorethamine; Methoxsalen; Neoplasms

1982
Current status of hemapheresis in the United States.
    Journal of clinical apheresis, 1991, Volume: 6, Issue:2

    Topics: Blood Banks; Blood Component Removal; Blood Transfusion, Autologous; Data Collection; Hematopoietic

1991
[Problems posed by the therapeutic use of photosensitizers in dermatology].
    Biochimie, 1986, Volume: 68, Issue:6

    Topics: 5-Methoxypsoralen; Coal Tar; DNA; Furocoumarins; Hematoporphyrin Derivative; Hematoporphyrin Photora

1986

Other Studies

12 other studies available for methoxsalen and Neoplasms

ArticleYear
ABC-transporter blockage mediated by xanthotoxin and bergapten is the major pathway for chemosensitization of multidrug-resistant cancer cells.
    Toxicology and applied pharmacology, 2017, 12-15, Volume: 337

    Topics: 5-Methoxypsoralen; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B;

2017
Methoxsalen with ultraviolet A therapy.
    Report on carcinogens : carcinogen profiles, 2011, Volume: 12

    Topics: Animals; Carcinogenicity Tests; Carcinogens, Environmental; Environmental Exposure; Government Regul

2011
Ultra-violet carcinogenesis in albino and pigmented mice receiving furocoumarins: psoralen and 8-methoxypsoralen.
    Nature, 1959, Mar-14, Volume: 183, Issue:4663

    Topics: Animals; Carcinogenesis; Coumarins; Ficusin; Furans; Furocoumarins; Methoxsalen; Mice; Neoplasms; Ne

1959
Erythema and tumor formation in methoxsalen-treated mice exposed to flourescent light.
    Archives of dermatology, 1960, Volume: 82

    Topics: Animals; Dermatitis, Phototoxic; Erythema; Humans; Light; Methoxsalen; Mice; Neoplasms; Photosensiti

1960
PSORALEN PROPHYLAXIS AGAINST SKIN CANCER: REPORT OF CLINICAL TRIAL I.
    The Journal of investigative dermatology, 1963, Volume: 41

    Topics: Ficusin; Geriatrics; Methoxsalen; Neoplasms; Skin Neoplasms; Sunburn; Toxicology

1963
PSORALEN PROPHYLAXIS AGAINST SKIN CANCER: REPORT OF CLINICAL TRIAL II.
    The Journal of investigative dermatology, 1963, Volume: 41

    Topics: Ficusin; Humans; Methoxsalen; Neoplasms; Skin Neoplasms; Sunburn; Toxicology

1963
[ON THE ANTINEOPLASTIC ACTIVITY OF SOME FUROCOUMARINS].
    Voprosy onkologii, 1964, Volume: 10

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Coumarins; Furans; Furocoumarins; Khellin;

1964
Sunscreens and their side effects.
    The Medical journal of Australia, 1981, Nov-14, Volume: 2, Issue:10

    Topics: 5-Methoxypsoralen; Humans; Methoxsalen; Neoplasms; Perfume; Sunscreening Agents

1981
[Psoriasis and PUVA].
    Deutsche medizinische Wochenschrift (1946), 1979, Nov-02, Volume: 104, Issue:44

    Topics: Humans; Methoxsalen; Neoplasms; Photochemotherapy; Psoriasis; Ultraviolet Therapy

1979
Photocarcinogenesis by methoxypsoralen, neutral red and proflavine.
    Bollettino chimico farmaceutico, 1979, Volume: 118, Issue:7

    Topics: Acridines; Animals; Breast Neoplasms; Female; Methoxsalen; Mice; Neoplasms; Neutral Red; Phenazines;

1979
Phototoxicity and photocarcinogenesis: comparative effects of anthracene and 8-methoxypsoralen in the skin of mice.
    Food and cosmetics toxicology, 1976, Volume: 14, Issue:4

    Topics: Animals; Anthracenes; Erythema; Methoxsalen; Mice; Neoplasms; Neoplasms, Experimental; Neoplasms, Ra

1976
Letter: Selection of carriers for alkylating moieties to increase their antitumor specificity.
    Cancer treatment reports, 1976, Volume: 60, Issue:3

    Topics: Alkylating Agents; Animals; Biopharmaceutics; Chemical Phenomena; Chemistry; Humans; Methoxsalen; Ne

1976