methoxsalen has been researched along with Nausea in 10 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-eight patients with plaque-type psoriasis were enrolled in a double-blind psoralen plus ultraviolet A (PUVA) treatment study comparing the efficacy and side effects of 5-methoxypsoralen (5-MOP) and 8-methoxypsoralen (8-MOP)." | 9.07 | Treatment of psoriasis with psoralens and ultraviolet A. A double-blind comparison of 8-methoxypsoralen and 5-methoxypsoralen. ( Berg, M; Ros, AM, 1994) |
| "Thirty-eight patients with plaque-type psoriasis were enrolled in a double-blind psoralen plus ultraviolet A (PUVA) treatment study comparing the efficacy and side effects of 5-methoxypsoralen (5-MOP) and 8-methoxypsoralen (8-MOP)." | 5.07 | Treatment of psoriasis with psoralens and ultraviolet A. A double-blind comparison of 8-methoxypsoralen and 5-methoxypsoralen. ( Berg, M; Ros, AM, 1994) |
| "The purpose of this study was to investigate a possible effect of metoclopramide on the bioavailability of 8-MOP since these drugs are frequently combined to prevent nausea, a common side effect of systemic 8-MOP." | 3.69 | Influence of metoclopramide on the pharmacokinetics of 8-methoxypsoralen. ( Fathi, M; Piletta, PA; Salomon, D; Saurat, JH; Studer-Sachsenberg, EM, 1997) |
| "Ten patients with systemic lupus erythematosus (SLE) were treated with ECP in an open clinical trial." | 2.67 | Extracorporeal photochemotherapy for the treatment of systemic lupus erythematosus. A pilot study. ( Graninger, W; Knobler, RM; Lindmaier, A; Smolen, JS; Trautinger, F, 1992) |
| "Phototoxicity is the most significant short-term adverse effect of PUVA therapy." | 1.30 | PUVA-induced phototoxicity: incidence and causes. ( Beck, L; Marwaha, S; Morison, WL, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wackernagel, A | 1 |
| Hofer, A | 1 |
| Legat, F | 1 |
| Kerl, H | 1 |
| Wolf, P | 1 |
| Berg, M | 1 |
| Ros, AM | 1 |
| Knobler, RM | 2 |
| Trautinger, F | 2 |
| Graninger, W | 3 |
| Macheiner, W | 1 |
| Gruenwald, C | 1 |
| Neumann, R | 1 |
| Ramer, W | 1 |
| Bolognia, JL | 1 |
| Freije, L | 1 |
| Amici, L | 1 |
| Dellostritto, J | 1 |
| Gasparro, FP | 1 |
| Morison, WL | 1 |
| Marwaha, S | 1 |
| Beck, L | 1 |
| Studer-Sachsenberg, EM | 1 |
| Piletta, PA | 1 |
| Fathi, M | 1 |
| Saurat, JH | 1 |
| Salomon, D | 1 |
| Rosten, M | 1 |
| Warin, AP | 1 |
| Carruthers, JA | 1 |
| Melski, JW | 1 |
| Tanenbaum, L | 1 |
| Parrish, JA | 1 |
| Fitzpatrick, TB | 1 |
| Bleich, HL | 1 |
| Lindmaier, A | 1 |
| Smolen, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Adaption of the Skin Sun Sensitivity Scale for People With All Pigment Varieties[NCT01975038] | 292 participants (Actual) | Observational | 2013-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for methoxsalen and Nausea
| Article | Year |
|---|---|
Editorial: Photochemotherapy in psoriasis.
Topics: Animals; Cataract; Coumarins; Ficusin; Furocoumarins; Humans; Methoxsalen; Mice; Nausea; Pruritus; P | 1976 |
2 trials available for methoxsalen and Nausea
| Article | Year |
|---|---|
Treatment of psoriasis with psoralens and ultraviolet A. A double-blind comparison of 8-methoxypsoralen and 5-methoxypsoralen.
Topics: 5-Methoxypsoralen; Absorption; Adult; Aged; Chemical and Drug Induced Liver Injury; Double-Blind Met | 1994 |
Extracorporeal photochemotherapy for the treatment of systemic lupus erythematosus. A pilot study.
Topics: Adult; Aged; Biopsy; Cell Survival; Humans; Hypotension; Immunity, Cellular; Leukapheresis; Lupus Er | 1992 |
7 other studies available for methoxsalen and Nausea
| Article | Year |
|---|---|
Efficacy of 8-methoxypsoralen vs. 5-methoxypsoralen plus ultraviolet A therapy in patients with mycosis fungoides.
Topics: 5-Methoxypsoralen; Adult; Aged; Aged, 80 and over; Epidemiologic Methods; Female; Humans; Male; Meth | 2006 |
Parenteral administration of 8-methoxypsoralen in photopheresis.
Topics: Administration, Oral; Capsules; Cell Survival; Chromatography, High Pressure Liquid; Humans; Infusio | 1993 |
Rectal suppositories of 8-methoxsalen produce fewer gastrointestinal side effects than the oral formulation.
Topics: Abdominal Pain; Administration, Oral; Administration, Rectal; Crystallization; Headache; Humans; Int | 1996 |
PUVA-induced phototoxicity: incidence and causes.
Topics: Clinical Protocols; Dermatitis, Phototoxic; Doxycycline; Drug Interactions; Female; Herpes Zoster; H | 1997 |
Influence of metoclopramide on the pharmacokinetics of 8-methoxypsoralen.
Topics: Administration, Oral; Adult; Age Factors; Antiemetics; Area Under Curve; Biological Availability; Ch | 1997 |
Photochemotherapy of psoriasis (PUVA).
Topics: Administration, Oral; Adolescent; Erythema; Female; Humans; Methoxsalen; Nausea; Photochemotherapy; | 1979 |
Oral methoxsalen photochemotherapy for the treatment of psoriasis: a cooperative clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; Erythema; Female; Humans; Ma | 1977 |