Page last updated: 2024-10-31

methoxsalen and Maculopapular Cutaneous Mastocytosis

methoxsalen has been researched along with Maculopapular Cutaneous Mastocytosis in 4 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Research Excerpts

ExcerptRelevanceReference
" In one patient who showed a lower absorption rate of 8-MOP plasma levels varied from 0-126 ng/ml."1.26Intraindividual variations of 8-methoxypsoralen plasma levels. ( Korting, HC; Schäfer-Korting, M, 1982)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schäfer-Korting, M1
Korting, HC1
Mackey, S1
Pride, HB1
Tyler, WB1
Godt, O1
Proksch, E1
Streit, V1
Christophers, E2
Hönigsmann, H1
Wolff, K1
Langner, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Single Arm Study of Extracorporeal Photoimmune Therapy With Uvadex For Corticosteroid Sparing in Patients With Corticosteroid-Dependent Crohn's Disease Who May Also Be Refractory or Intolerant to Immunosuppressants and/or Anti-Tumor Necrosis Factor Agen[NCT00056355]Phase 110 participants Interventional2003-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for methoxsalen and Maculopapular Cutaneous Mastocytosis

ArticleYear
Intraindividual variations of 8-methoxypsoralen plasma levels.
    Archives of dermatological research, 1982, Volume: 272, Issue:1-2

    Topics: Adult; Aged; Biological Availability; Female; Humans; Intestinal Absorption; Liver; Male; Metabolic

1982
Diffuse cutaneous mastocytosis. Treatment with oral psoralen plus UV-A.
    Archives of dermatology, 1996, Volume: 132, Issue:12

    Topics: Administration, Oral; Beverages; Female; Fruit; Humans; Infant; Methoxsalen; Photosensitizing Agents

1996
Short- and long-term effectiveness of oral and bath PUVA therapy in urticaria pigmentosa and systemic mastocytosis.
    Dermatology (Basel, Switzerland), 1997, Volume: 195, Issue:1

    Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Age of Onset; Baths; Body Surfac

1997
PUVA-treatment of urticaria pigmentosa.
    The British journal of dermatology, 1978, Volume: 98, Issue:6

    Topics: Adult; Aged; Child; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Ultraviolet T

1978