methoxsalen has been researched along with Lupus Erythematosus, Systemic in 5 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ten patients with systemic lupus erythematosus (SLE) were treated with ECP in an open clinical trial." | 2.67 | Extracorporeal photochemotherapy for the treatment of systemic lupus erythematosus. A pilot study. ( Graninger, W; Knobler, RM; Lindmaier, A; Smolen, JS; Trautinger, F, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arjumand, S | 1 |
| Ali, A | 1 |
| Stern, RS | 1 |
| Morison, WL | 1 |
| Thibodeau, LA | 1 |
| Kleinerman, RA | 1 |
| Parrish, JA | 1 |
| Geer, DE | 1 |
| Fitzpatrick, TB | 1 |
| Knobler, RM | 2 |
| Graninger, W | 3 |
| Lindmaier, A | 2 |
| Trautinger, F | 2 |
| Smolen, JS | 1 |
| Berry, CZ | 1 |
| Goldberg, LC | 1 |
| Shepard, WL | 1 |
2 trials available for methoxsalen and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
Antinuclear antibodies and oral methoxsalen photochemotherapy (PUVA) for psoriasis.
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Child; Child, Preschool; Clinical Trials as Topic; | 1979 |
Extracorporeal photochemotherapy for the treatment of systemic lupus erythematosus. A pilot study.
Topics: Adult; Aged; Biopsy; Cell Survival; Humans; Hypotension; Immunity, Cellular; Leukapheresis; Lupus Er | 1992 |
3 other studies available for methoxsalen and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
Cross-reactions of human lupus autoantibodies with 8-methoxypsoralen photomodified DNA fragments.
Topics: Animals; Autoantibodies; Cross Reactions; Cross-Linking Reagents; DNA; Enzyme-Linked Immunosorbent A | 1994 |
Photopheresis for the treatment of lupus erythematosus. Preliminary observations.
Topics: Adult; Aged; Cell Survival; Humans; Leukapheresis; Lupus Erythematosus, Systemic; Methoxsalen; Middl | 1991 |
Systemic lupus erythematosus complicated by coccidioidomycosis.
Topics: Adrenocorticotropic Hormone; Adult; Amphotericin B; Chloroquine; Coccidioidomycosis; Cortisone; Fema | 1968 |