methoxsalen has been researched along with Lung Neoplasms in 6 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Despite progress in diagnostics and treatment of hepatocellular carcinoma (HCC), its prognosis remains poor." | 1.43 | The anti-metastatic effect of 8-MOP on hepatocellular carcinoma is potentiated by the down-regulation of bHLH transcription factor DEC1. ( Liu, J; Luo, W; Shan, E; Xi, T; Xiong, J; Yang, H; Yang, J; Zhang, F, 2016) |
| "Pretreatment of methoxsalen significantly reduced tumor incidence from 93." | 1.32 | Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice. ( Ikeda, M; Imaida, K; Kamataki, T; Maeta, H; Miyazaki, M; Saoo, K; Takeuchi, H; Yamazaki, H; Yokohira, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Vrzal, R | 1 |
| Xiong, J | 1 |
| Yang, H | 1 |
| Luo, W | 1 |
| Shan, E | 1 |
| Liu, J | 1 |
| Zhang, F | 1 |
| Xi, T | 1 |
| Yang, J | 1 |
| Kuno, T | 1 |
| Yokohira, M | 4 |
| Matsuda, Y | 2 |
| Suzuki, S | 1 |
| Hashimoto, N | 1 |
| Yamakawa, K | 2 |
| Saoo, K | 4 |
| Imaida, K | 4 |
| Takeuchi, H | 3 |
| Ikeda, M | 1 |
| Maeta, H | 1 |
| Miyazaki, M | 3 |
| Yamazaki, H | 2 |
| Kamataki, T | 3 |
| Zeng, Y | 1 |
| Fujieda, M | 1 |
| Masumura, K | 1 |
| Nohmi, T | 1 |
| Funae, Y | 1 |
1 review available for methoxsalen and Lung Neoplasms
| Article | Year |
|---|---|
Genetic and Enzymatic Characteristics of CYP2A13 in Relation to Lung Damage.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Gene Expression Regulation, Enzymologic; Gene Expression Reg | 2021 |
5 other studies available for methoxsalen and Lung Neoplasms
| Article | Year |
|---|---|
The anti-metastatic effect of 8-MOP on hepatocellular carcinoma is potentiated by the down-regulation of bHLH transcription factor DEC1.
Topics: Animals; Antineoplastic Agents; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Hepatocellu | 2016 |
Lack of modifying potential of 8-methoxypsoralen in the promotion or progression stages of lung carcinogenesis in A/J female mice.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P450 Family 2; Disease P | 2008 |
Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice.
Topics: Animals; Anticarcinogenic Agents; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cytochrome P-450 CYP2A | 2003 |
Dose dependent inhibitory effects of dietary 8-methoxypsoralen on NNK-induced lung tumorigenesis in female A/J mice.
Topics: Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cytochrome P-450 CYP2A6; | 2006 |
Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung adenomas.
Topics: Adenoma; Animals; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Carcinogens; Chemoprevention | 2005 |