methoxsalen has been researched along with Liver Neoplasms in 4 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The chemopreventive role of 5-methoxypsoralen (5-MOP) in the human hepatocellular carcinoma (HCC) cell line was investigated by studying the regulation of proliferation and apoptosis in HCC (J5) cells." | 7.72 | Effect of 5-methoxypsoralen (5-MOP) on cell apoptosis and cell cycle in human hepatocellular carcinoma cell line. ( Chen, SF; Chung, JG; Lee, YM; Wu, TH, 2003) |
| "The chemopreventive role of 5-methoxypsoralen (5-MOP) in the human hepatocellular carcinoma (HCC) cell line was investigated by studying the regulation of proliferation and apoptosis in HCC (J5) cells." | 3.72 | Effect of 5-methoxypsoralen (5-MOP) on cell apoptosis and cell cycle in human hepatocellular carcinoma cell line. ( Chen, SF; Chung, JG; Lee, YM; Wu, TH, 2003) |
| "Despite progress in diagnostics and treatment of hepatocellular carcinoma (HCC), its prognosis remains poor." | 1.43 | The anti-metastatic effect of 8-MOP on hepatocellular carcinoma is potentiated by the down-regulation of bHLH transcription factor DEC1. ( Liu, J; Luo, W; Shan, E; Xi, T; Xiong, J; Yang, H; Yang, J; Zhang, F, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, H | 2 |
| Xiong, J | 3 |
| Luo, W | 2 |
| Yang, J | 3 |
| Xi, T | 2 |
| Shan, E | 1 |
| Liu, J | 1 |
| Zhang, F | 1 |
| Peng, Y | 1 |
| Liu, W | 1 |
| Gui, HY | 1 |
| Feng, XM | 1 |
| Chen, RN | 1 |
| Hu, G | 1 |
| Lee, YM | 1 |
| Wu, TH | 1 |
| Chen, SF | 1 |
| Chung, JG | 1 |
4 other studies available for methoxsalen and Liver Neoplasms
| Article | Year |
|---|---|
8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition.
Topics: Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Li | 2015 |
The anti-metastatic effect of 8-MOP on hepatocellular carcinoma is potentiated by the down-regulation of bHLH transcription factor DEC1.
Topics: Animals; Antineoplastic Agents; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Hepatocellu | 2016 |
Down regulation of differentiated embryonic chondrocytes 1 (DEC1) is involved in 8-methoxypsoralen-induced apoptosis in HepG2 cells.
Topics: Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Hepatocellular; Caspase 3; Caspa | 2012 |
Effect of 5-methoxypsoralen (5-MOP) on cell apoptosis and cell cycle in human hepatocellular carcinoma cell line.
Topics: 5-Methoxypsoralen; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Chemoprevention; Cyclin B; Cycl | 2003 |