Page last updated: 2024-10-31

methoxsalen and Itching

methoxsalen has been researched along with Itching in 11 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Research Excerpts

ExcerptRelevanceReference
"Thirty patients with recalcitrant psoriasis were treated with topical methoxsalen and blacklight (UVA)."7.65Topical methoxsalen and blacklight in the treatment of psoriasis. ( Kaidbey, KM; Kligman, AM; Petrozzi, JW, 1977)
"Thirty patients with recalcitrant psoriasis were treated with topical methoxsalen and blacklight (UVA)."3.65Topical methoxsalen and blacklight in the treatment of psoriasis. ( Kaidbey, KM; Kligman, AM; Petrozzi, JW, 1977)
"Aquagenic pruritus is a rare but distinct entity in which intense itching develops after contact with water, in the absence of cutaneous signs or underlying disorders that could explain the symptoms."1.31Aquagenic pruritus responding to intermittent photochemotherapy. ( Anstey, AV; Holme, SA, 2001)
"The results of the first six months of treatment of psoriasis with photochemotherapy in the Skin and Cancer Foundation's clinic resulted in 30 out of 53 patients being completely clear of psoriasis lesions, 14 showing progressive improvement (and subsequently clearing), four failures, and five withdrawals."1.26Photochemotherapy in psoriasis: the first six months in Australia. ( King, R; O'Brien, H; Paver, K; Poyzer, K, 1979)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's3 (27.27)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rodríguez-Granados, MT1
Carrascosa, JM1
Gárate, T1
Gómez-Díez, S1
Guimaraens-Juantorena, D1
Jeanmougin, M1
Rain, JD1
Najean, Y1
Godt, O1
Proksch, E1
Streit, V1
Christophers, E1
Calzavara-Pinton, P1
Holme, SA1
Anstey, AV1
Rosten, M1
Mackey, JP1
King, R1
Poyzer, K1
Paver, K1
O'Brien, H1
Warin, AP1
Carruthers, JA1
Petrozzi, JW1
Kaidbey, KM1
Kligman, AM1
Melski, JW1
Tanenbaum, L1
Parrish, JA1
Fitzpatrick, TB1
Bleich, HL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Adaption of the Skin Sun Sensitivity Scale for People With All Pigment Varieties[NCT01975038]292 participants (Actual)Observational2013-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for methoxsalen and Itching

ArticleYear
Editorial: Photochemotherapy in psoriasis.
    Clinical and experimental dermatology, 1976, Volume: 1, Issue:2

    Topics: Animals; Cataract; Coumarins; Ficusin; Furocoumarins; Humans; Methoxsalen; Mice; Nausea; Pruritus; P

1976

Trials

2 trials available for methoxsalen and Itching

ArticleYear
Efficacy of photochemotherapy on severe pruritus in polycythemia vera.
    Annals of hematology, 1996, Volume: 73, Issue:2

    Topics: Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemotherapy; Photosensitizing Agents; Po

1996
Narrow band UVB (311 nm) phototherapy and PUVA photochemotherapy: a combination.
    Journal of the American Academy of Dermatology, 1998, Volume: 38, Issue:5 Pt 1

    Topics: Administration, Cutaneous; Adult; Aged; Dermatitis, Phototoxic; Erythema; Humans; Male; Methoxsalen;

1998

Other Studies

8 other studies available for methoxsalen and Itching

ArticleYear
[Consensus document on bath-PUVA therapy. The Spanish Photobiology Group of the Spanish Academy of Dermatology and Venereology].
    Actas dermo-sifiliograficas, 2007, Volume: 98, Issue:3

    Topics: Administration, Cutaneous; Baths; Dermatitis, Phototoxic; Dose-Response Relationship, Drug; Dose-Res

2007
Short- and long-term effectiveness of oral and bath PUVA therapy in urticaria pigmentosa and systemic mastocytosis.
    Dermatology (Basel, Switzerland), 1997, Volume: 195, Issue:1

    Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Age of Onset; Baths; Body Surfac

1997
Aquagenic pruritus responding to intermittent photochemotherapy.
    Clinical and experimental dermatology, 2001, Volume: 26, Issue:1

    Topics: Administration, Oral; Humans; Male; Methoxsalen; Middle Aged; Pruritus; PUVA Therapy; Treatment Outc

2001
Photochemotherapy of psoriasis (PUVA).
    The New Zealand medical journal, 1979, Aug-08, Volume: 90, Issue:641

    Topics: Administration, Oral; Adolescent; Erythema; Female; Humans; Methoxsalen; Nausea; Photochemotherapy;

1979
Clinical side-effects of long-wave ultraviolet light and oral 8-methoxypsoralen in patients treated for psoriasis.
    Irish journal of medical science, 1979, Volume: 148, Issue:2

    Topics: Female; Hirsutism; Humans; Methoxsalen; Photochemotherapy; Pruritus; Psoriasis; Ultraviolet Therapy

1979
Photochemotherapy in psoriasis: the first six months in Australia.
    The Medical journal of Australia, 1979, Jan-13, Volume: 1, Issue:1

    Topics: Australia; Darier Disease; Dermatitis; Edema; Erythema; Humans; Methoxsalen; Photochemotherapy; Prur

1979
Topical methoxsalen and blacklight in the treatment of psoriasis.
    Archives of dermatology, 1977, Volume: 113, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Aged; Blister; Child; Female; Humans; Male; Methoxsalen;

1977
Oral methoxsalen photochemotherapy for the treatment of psoriasis: a cooperative clinical trial.
    The Journal of investigative dermatology, 1977, Volume: 68, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; Erythema; Female; Humans; Ma

1977