methoxsalen has been researched along with Inflammation in 13 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Analog 19 was a more potent anti-inflammatory agent than the reference compound indomethacin and of comparable cytocompatibility to 8-MOP whereas analog 24 was a weaker inhibitor of inflammation than indomethacin and significantly more cytotoxic than 8-MOP." | 3.79 | Syntheses and evaluation of the antioxidant activity of novel methoxypsoralen derivatives. ( Athanassopoulos, CM; Avgoustakis, K; Bariamis, SE; Hadjipavlou-Litina, D; Kontogiorgis, C; Marin, M; Papaioannou, D; Romeo, G; Sindona, G; Tsimali, Z, 2013) |
| "Heat and mechanical hyperalgesia were evaluated by radiant heat and von Frey filament tests, respectively." | 1.91 | Mechanisms involved in the antinociceptive and anti-inflammatory effects of xanthotoxin. ( Guo, J; Song, Y; Tang, J; Tang, Z; Yang, Y; Yu, G; Zhu, C, 2023) |
| "Bovine mastitis is the most common disease in dairy cattle." | 1.51 | 8-Methoxypsoralen protects bovine mammary epithelial cells against lipopolysaccharide-induced inflammatory injury via suppressing JAK/STAT and NF-κB pathway. ( Gong, P; Li, J; Liu, F; Lv, A; Yin, P; Zhang, Z, 2019) |
| "These blebs also displayed a high exposure of the antigens CD5 and CD8 as well as a low exposure of CD28 and CD86." | 1.35 | Photopheresis with UV-A light and 8-methoxypsoralen leads to cell death and to release of blebs with anti-inflammatory phenotype in activated and non-activated lymphocytes. ( Fietkau, R; Finzel, S; Frey, B; Gaipl, US; Herrmann, M; Hueber, A; Munoz, LE; Rech, J; Stadler, K, 2009) |
| "Erythema was graded visually." | 1.28 | Photoinduced cutaneous inflammatory response by psoralens. ( Haberman, HF; Kumar, JR; Menon, IA; Ranadive, NS, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Bariamis, SE | 1 |
| Marin, M | 1 |
| Athanassopoulos, CM | 1 |
| Kontogiorgis, C | 1 |
| Tsimali, Z | 1 |
| Papaioannou, D | 1 |
| Sindona, G | 1 |
| Romeo, G | 1 |
| Avgoustakis, K | 1 |
| Hadjipavlou-Litina, D | 1 |
| Sayed, AS | 1 |
| El Sayed, NS | 1 |
| Budzyńska, B | 1 |
| Skalicka-Woźniak, K | 1 |
| Ahmed, MK | 1 |
| Kandil, EA | 1 |
| Zhu, C | 1 |
| Yang, Y | 2 |
| Song, Y | 1 |
| Guo, J | 1 |
| Yu, G | 1 |
| Tang, J | 1 |
| Tang, Z | 1 |
| Zheng, K | 1 |
| Mei, W | 1 |
| Wang, Y | 1 |
| Yu, C | 1 |
| Yu, B | 1 |
| Deng, S | 1 |
| Hu, J | 1 |
| Li, J | 1 |
| Yin, P | 1 |
| Gong, P | 1 |
| Lv, A | 1 |
| Zhang, Z | 1 |
| Liu, F | 1 |
| Kuzmina, Z | 1 |
| Stroncek, D | 1 |
| Pavletic, SZ | 1 |
| Di Biaso, I | 1 |
| Di Maio, L | 1 |
| Bugarin, C | 1 |
| Gaipa, G | 1 |
| Dander, E | 1 |
| Balduzzi, A | 1 |
| Parma, M | 1 |
| D'Amico, G | 1 |
| Perseghin, P | 1 |
| Biondi, A | 1 |
| Biagi, E | 1 |
| Stadler, K | 1 |
| Frey, B | 1 |
| Munoz, LE | 1 |
| Finzel, S | 1 |
| Rech, J | 1 |
| Fietkau, R | 1 |
| Herrmann, M | 1 |
| Hueber, A | 1 |
| Gaipl, US | 1 |
| Muret, P | 1 |
| Makki, S | 1 |
| Urien, S | 1 |
| Agache, P | 1 |
| Bechtel, P | 1 |
| Tillement, JP | 1 |
| Greaves, MW | 1 |
| Hensby, CN | 1 |
| Black, AK | 1 |
| Plummer, NA | 1 |
| Fincham, N | 1 |
| Warin, AP | 1 |
| Camp, R | 1 |
| Eaglstein, WH | 1 |
| Sakai, M | 1 |
| Mizuno, N | 1 |
| Kumar, JR | 1 |
| Ranadive, NS | 1 |
| Menon, IA | 1 |
| Haberman, HF | 1 |
1 review available for methoxsalen and Inflammation
| Article | Year |
|---|---|
Extracorporeal photopheresis as a therapy for autoimmune diseases.
Topics: Apoptosis; Autoimmune Diseases; Blood Component Removal; Clinical Trials as Topic; Humans; Immune To | 2015 |
12 other studies available for methoxsalen and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Syntheses and evaluation of the antioxidant activity of novel methoxypsoralen derivatives.
Topics: Anti-Inflammatory Agents; Antioxidants; Dose-Response Relationship, Drug; Furocoumarins; Glycine max | 2013 |
Xanthotoxin modulates oxidative stress, inflammation, and MAPK signaling in a rotenone-induced Parkinson's disease model.
Topics: alpha-Synuclein; Animals; Antioxidants; Dopamine; Dopaminergic Neurons; Inflammation; Methoxsalen; M | 2022 |
Mechanisms involved in the antinociceptive and anti-inflammatory effects of xanthotoxin.
Topics: Acute Pain; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Chronic Pain; Formaldehyde; Ga | 2023 |
Anti-inflammatory and proresolution activities of bergapten isolated from the roots of Ficus hirta in an in vivo zebrafish model.
Topics: 5-Methoxypsoralen; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Female; Ficus; Inflamm | 2018 |
8-Methoxypsoralen protects bovine mammary epithelial cells against lipopolysaccharide-induced inflammatory injury via suppressing JAK/STAT and NF-κB pathway.
Topics: Animals; Cattle; Epithelial Cells; Female; Inflammation; Janus Kinases; Lipopolysaccharides; Mammary | 2019 |
Regulatory T cells and extracorporeal photochemotherapy: correlation with clinical response and decreased frequency of proinflammatory T cells.
Topics: Graft vs Host Disease; Humans; Inflammation; Methoxsalen; Photopheresis; T-Lymphocytes; T-Lymphocyte | 2009 |
Photopheresis with UV-A light and 8-methoxypsoralen leads to cell death and to release of blebs with anti-inflammatory phenotype in activated and non-activated lymphocytes.
Topics: Antigens, Surface; Apoptosis; Blister; Cells, Cultured; Humans; Inflammation; Lymphocyte Activation; | 2009 |
Binding of 5-methoxypsoralen to blood fractions. Influence of albumin and free fatty acids: an in vitro study.
Topics: 5-Methoxypsoralen; Blood Proteins; Erythrocytes; Extracellular Space; Fatty Acids; gamma-Globulins; | 1993 |
Inflammatory reactions induced by ultraviolet irradiation.
Topics: Arachidonic Acids; Cell Differentiation; Cyclic AMP; Erythema; Humans; Indomethacin; Inflammation; M | 1978 |
Ultraviolet radiation-induced inflammation and leukocytes.
Topics: Animals; Cell Count; Cyclophosphamide; Erythema; Guinea Pigs; Inflammation; Leukocytes; Leukopenia; | 1979 |
Photoinduced cutaneous inflammatory response by psoralens.
Topics: Administration, Topical; Animals; Darkness; Dose-Response Relationship, Drug; Erythema; Inflammation | 1992 |